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kevinbolding.bsky.social @kevinbolding.bsky.social · Jul 15

I really enjoy this paper, but I was wondering if there is any demonstration of PV and SOM cells producing different inhibitory dynamics in putative post-synaptic partners.

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kevinbolding.bsky.social @kevinbolding.bsky.social · Jul 15

Anyone know where to find an example of an inhibitory cross-correlogram produced by a somatostatin interneuron? #neuroskyence

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kevinbolding.bsky.social @kevinbolding.bsky.social · Mar 28

youtu.be/JZIv0KV71S4?...

김정미 - 추억 (1973 초판), Kim Jung Mi, Memories

YouTube video by 집고양이

youtu.be

Reposted by kevinbolding.bsky.social

Matteo Carandini @carandinilab.net · Feb 7

Neuropixels and Optogenetics are delighted to announce the birth of

Neuropixels Opto

Combining high-resolution electrophysiology and optogenetics

Today in bioRxiv

960 sites, 28 emitters, 2 colors

By Lakunina, @karolinazsocha.bsky.social, Ladd, et al

www.biorxiv.org/content/10.1...

(1/2)

A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.

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Reposted by kevinbolding.bsky.social

Tim Kietzmann @timkietzmann.bsky.social · Feb 6

This year we ran another meme contest as part of my ML4CCN lecture series. Student submissions were fantastic.

Guess the paper...

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Reposted by kevinbolding.bsky.social

gtavosanis.bsky.social @gtavosanis.bsky.social · Jan 27

Excited to share our new preprint: How does the fly mushroom body support odour categorisation and discrimination? 🧠✨ Dive into Ivy Chan's @ivychanchiwai.bsky.social findings on how neural circuits enable complex olfactory processing in flies. Check it out here:
www.biorxiv.org/content/10.1...

Odour representations supporting ethology-relevant categorisation and discrimination in the Drosophila mushroom body

Neural representations of sensory stimuli serve multiple distinct purposes, from the rapid recognition of familiar environments, to the precise identification of individual salient cues. In the insect...

www.biorxiv.org

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Reposted by kevinbolding.bsky.social

@dlp. @umadlp.bsky.social · Feb 2

John Cohen, Painter/Collage Artist/Graphic Designer Robert Rauschenberg Preparing for a Show at the Tanager Gallery, 10th St, New York City, 1959.

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Reposted by kevinbolding.bsky.social

Jonathan Lambert @jonlambert.bsky.social · Feb 2

NSF’s cash management service is now back up and running.

Seems like they responded to the court order.

new.nsf.gov/executive-or...

NSF Implementation of Recent Executive Orders

Information for the NSF community regarding executive orders.

new.nsf.gov

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Reposted by kevinbolding.bsky.social

Christopher Dornan @chrisdornan.bsky.social · Feb 2

Here's the speech if you haven't heard it. 13 minutes of your time. Share it with your American friends and neighbours, because they won't see it otherwise. Circulate it in Mexico and Denmark, France and the UK, Panama and Germany, Poland and Estonia, and especially -- especially -- Ukraine.

Trudeau: Canada will retaliate with 25% tariffs on $155B of U.S. goods

YouTube video by CBC News

youtu.be

190 4.3K 7.3K

Reposted by kevinbolding.bsky.social

Daniel Gonzales @dgonzales1990.bsky.social · Jan 31

Really proud to see my postdoc work out!!

We used flexible, semi-transparent NeuroGrids to record traveling waves while simultaneously mapping cellular and subcellular dynamics with two-photon imaging

www.science.org/doi/10.1126/...

Touch-evoked traveling waves establish a translaminar spacetime code

Translaminar spacetime patterns organized by feedback-dependent cortical circuits support sparse traveling waves.

www.science.org

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Reposted by kevinbolding.bsky.social

Caitlin Mallory @caitlinmallory.bsky.social · Jan 31

1/19 I’m thrilled that my postdoctoral work, with John Widloski and David Foster is now out in @science.org, along with a wonderful preview by Daniel Bendor!

The time course and organization of hippocampal replay

The mechanisms by which the brain replays neural activity sequences remain unknown. Recording from large ensembles of hippocampal place cells in freely behaving rats, we observed that replay content i...

www.science.org

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Reposted by kevinbolding.bsky.social

Julian Meeks @meeksandmilds.bsky.social · Jan 31

Someone needs to be reaching out to these philanthropies to make it VERY CLEAR that the return on investment from their donations will TANK with NIH and NSF being affected, and that THEIR GOOD MONEY and investment is being being WASTED by these inexcusable (from a business angle) actions.

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Reposted by kevinbolding.bsky.social

Julian Meeks @meeksandmilds.bsky.social · Jan 31

Sources of philanthropic giving to biomedical science and training programs (graduate and medical school programs, etc.) are NOT going to backstop the loss of NIH, NSF Funding. They aren't able to do so, and many of them may not want attention.

BUT they have sway, and have money in the game.

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Reposted by kevinbolding.bsky.social

Karl Herrup @asparatics.bsky.social · Jan 30

My first science post here on BlueSky is a long one. Setting the contrarian tone from the very beginning, I take strong issue with the recent op-ed by Charles Piller published in the January 24th NY Times on #Alzheimer's disease (nam12.safelinks.protection.outlook.com?url=https%3A...)

Opinion | The Devastating Legacy of Lies in Alzheimer’s Science

Fraud in research needs to end.

nam12.safelinks.protection.outlook.com

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Reposted by kevinbolding.bsky.social

Alice Ting @aliceyting.bsky.social · Jan 30

Tetanus on demand! (not for bioweapons, but for neuroscience research)

Tetanus toxin induces paralysis by using a protease to cleave VAMP2, a protein required for synaptic vesicle fusion and neurotransmitter release.

To harness this toxicity and use it as a beneficial tool for neuroscience,

Painting by Sir Charles Bell depicting opisthotonos, which can be caused by tetanus (1809)

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Reposted by kevinbolding.bsky.social

Kindra Crick 🧩 @kindracrick.com · Jan 29

Capturing the detail of this monoprint as the writing reveals itself when viewed at an angle.

Writing is from a 1953 letter from my grandad, Francis Crick, to his 12 year old son detailing in simple terms how DNA was a code and how it might copy itself.

#sciart #dna

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Reposted by kevinbolding.bsky.social

Adrien Peyrache @apeyrache.bsky.social · Jan 28

🚨Important paper alert (a bit late, but see below)
Guo et al show that while place cells may not initially form a manifold reflecting the environment's topology, the topology is learned across days, during sleep.

www.cell.com/cell-reports...

Another story to tell about this paper 👇
1/5

Latent learning drives sleep-dependent plasticity in distinct CA1 subpopulations

Guo et al. find that when mice repeatedly explore a novel environment, a distinct subset of neurons in the CA1 region of the hippocampus, which initially exhibits weak spatial selectivity, gradually d...

www.cell.com

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Reposted by kevinbolding.bsky.social

Dinu F Albeanu @dinanthos.bsky.social · Jan 14

Interested in understanding how things work? In particular the tools you use to study the brain? Join us at TENSS 2025 where we brainstorm ideas, build and debug microscopes, electrophysiology and behavior rigs amidst the picturesque Transylvanian hills! tenss.ro
Apply by: February 16th!

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Reposted by kevinbolding.bsky.social

Bob Pellegrino @kingfunk.bsky.social · Jan 26

Alexander Fjaeldstad and I have a new chapter in the book Smell, Taste, Eat: The Role of the Chemical Senses in Eating Behaviour, edited by @LorenzoDStafford. Lots of great insights here.

From our chapter, it’s clear that smell loss and its impact on ingestion remain vastly underexplored."

The Effect of Olfactory Disorder (and Other Chemosensory Disorders) on Perception, Acceptance, and Consumption of Food

People with changes in the overall sensory experience of food often complain of taste disturbances, although the problem is normally caused by the loss of aroma in the food (thus an olfactory disorder...

link.springer.com

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kevinbolding.bsky.social @kevinbolding.bsky.social · Jan 26

The reveal of what she created here (the strings, the screamed chorus) had me crying laughing. Truly bonkers.

youtu.be/DwhbnN9hCtI

I Made Good Luck Babe By Chappell Roan Without Hearing It

YouTube video by Dev Limes

youtu.be

Reposted by kevinbolding.bsky.social

kevinbolding.bsky.social @kevinbolding.bsky.social · Jan 22

Does anybody have a favorite Cre recombinase antibody and staining protocol?
#neuroskyence

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Reposted by kevinbolding.bsky.social

Dayu Lin @moccalin.bsky.social · Jan 22

Antipsychotics is often used to suppress hyper-aggression. Does it really suppress aggression or just cause sedation? Antipsychotics targets dopamine receptors. Our new study revealed that dopamine modulates aggression based on animals' fighting experience.

www.nature.com/articles/s41...

Experience-dependent dopamine modulation of male aggression - Nature

Dopaminergic neurons in the ventral tegmental area have a role in modulating aggression in adult male mice, and this effect of dopamine depends strongly on fighting experience.

www.nature.com

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Reposted by kevinbolding.bsky.social

Dinu F Albeanu @dinanthos.bsky.social · Jan 23

New paper from the lab: feedback from piriform cortex to the olfactory bulb carries identity and reward contingency signals in a multimodal (odor and sound) rule-reversal task. Feedback is re-formatted within seconds and reflects changes in the perceived rules of engagement.
doi.org/10.1038/s414...

Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal - Nature Communications

Hernandez-Trejo, Ciuparu, and Garcia da Silva et al. report that the piriform-to-olfactory bulb feedback in the mouse carries multimodal identity and reward contingency signals, which are re-formatted...

doi.org

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kevinbolding.bsky.social @kevinbolding.bsky.social · Jan 22

Does anybody have a favorite Cre recombinase antibody and staining protocol?
#neuroskyence

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