Kjetill S Jakobsen
@kjetillsj.bsky.social
84 followers 79 following 13 posts
Evolutionary biologist studying functional, comparative and populations diversity processes
Posts Media Videos Starter Packs
Reposted by Kjetill S Jakobsen
naturalselection.bsky.social
🧨 The Naturhistoriska riksmuseet has a position open for a Tenure-Track group Leader position (DDLS fellow).

17 M SEK start-up (1.6 million euros, which will account for your salary / 2 PhDs / 2 Postdocs / plenty of money for starting projects and sending peoeple to conferences).

lnkd.in/d5jNr_Ti
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
Reposted by Kjetill S Jakobsen
genomebiolevol.bsky.social
The recent GBE Review on approaches to phylogenetic genotype to phenotype mapping is the focus of a new Highlight.

Highlight: Leveraging Phylogenomics to Uncover the Loci of Repeated Evolution

🔗 doi.org/10.1093/gbe/evaf164

#genome #evolution #phylogenetics
GBE | Highlight: Leveraging Phylogenomics to Uncover the Loci of Repeated Evolution
Reposted by Kjetill S Jakobsen
genomebiolevol.bsky.social
In a new Review article in GBE, @scientific-arlie.bsky.social et al delve into the growing field of phylogenetic genotype to phenotype mapping (PhyloG2P), discussing advances and future directions for using phylogenomic data to map traits to genomes

🔗 doi.org/10.1093/gbe/evaf150

#genome #evolution
GBE | From Trees to Traits: A Review of Advances in PhyloG2P Methods and Future Directions
Reposted by Kjetill S Jakobsen
plosbiology.org
Neuron-specific splicing of Agrin by Nova is essential for AChR clustering at the NMJ. @rnadoctor.bsky.social @lionlchristiaen.bsky.social &co show that this pathway is conserved in tunicates & that the transcription factor Ebf is a key activator of Nova expression @plosbiology.org 🧪 plos.io/3VhTwig
Top left: Two-color double ISH of Nova (green) and Islet (magenta) showing co-expression in the bilaterally symmetric Motor Neuron 2 (MN2) pair of cells (arrows). Note that Nova mRNA distribution appears more nuclear than Islet in these cells at this stage. Top right:  Summary model diagram of a conserved Nova-Agrin-Lrp4 pathway for AChR clustering in Ciona. Upper panel: Summary of conserved pathway, and previously unidentified Ebf-Nova regulatory connection identified in Ciona. Lower panel: Model of proposed mechanism for Ciona Nova-dependent alternative Agrin splicing via binding of KH1 and KH2 domains to two YCAY-rich NISEs identified in the intron 3′ to the Z exons (though not known in what exact orientation or configuration). Inhibitory effect of KH3 domain is relieved by the N- and C-termini. Diagram not drawn to scale. Bottom: Neural-specific CRISPR-mediated disruption of Agrin using sgRNAs results in loss of Acetylcholine receptor A1::GFP clusters (AChRA1::GFP, green) in tail muscles, driven by the Tbx6-r.b promoter. Motor neuron axons labeled by VAChT > Unc-76::mCherry in magenta.
Reposted by Kjetill S Jakobsen
friedmanlab.bsky.social
Do you like cichlids? Fossils? Fossil cichlids? Would you like to study them as part of a graduate degree at the University of Michigan, joining an NSF-funded project? Get in touch.
Multicolored CT model of a fossil cichlid skeleton. Image credit: Austin Babut (project technician).
Reposted by Kjetill S Jakobsen
animalculum.bsky.social
#Arctic #algae aren't immobile or entombed. They're not just surviving either—they're gliding into record books phys.org/news/2025-09...

Ice gliding #diatoms establish record-low temperature limits for motility in a eukaryotic cell www.pnas.org/doi/10.1073/...

#protists #microbes #extremophiles
schematic pictures and microscopic photos showing various aspects of movement in single-celled algae
Reposted by Kjetill S Jakobsen
Reposted by Kjetill S Jakobsen
crouxevo.bsky.social
Hybridization and introgression are major evolutionary processes. Since the 1940s, the prevailing view has been that they shape plants far more than animals. In our new study (www.science.org/doi/10.1126/...
), we find the opposite: animals exchange genes more, and for longer, than plants
Reposted by Kjetill S Jakobsen
relenski.bsky.social
Curious to hear thoughts from #popgen, #humangenetics, #genomics folks on recent paper:

www.pnas.org/doi/10.1073/...

"Directed mutation" in specific human pop'ns seems unlikely to me. DM didn't stand up as proposed in bacteria, but there are hot spots shaped by past selection. Plausible here?
Reposted by Kjetill S Jakobsen
biorxiv-evobio.bsky.social
Parallel but distinct adaptive routes in the budding and fission yeasts after 10,000 generations of experimental evolution https://www.biorxiv.org/content/10.1101/2025.09.11.675703v1
Reposted by Kjetill S Jakobsen
rose.bsky.team
People are talking about Bluesky! From data analyzed between Jan 1 — Aug 18, 2025, we captured 85.5% of share of voice across social, digital, and traditional media, according to Meltwater. This is what death looks like 💀
Screenshot of Meltwater report showing Bluesky is 85.5% of mentions across platforms while other social platforms are much lower Screenshot of Meltwater report showing Bluesky mentions by search is 10x higher than the alt platform, Threads
Reposted by Kjetill S Jakobsen
vdbijl.bsky.social
Our paper on the genetics of guppy color patterns has now been assigned an issue in NEE: doi.org/10.1038/s415...

With this paper, we also publish all 14,100 guppy photos used in the study, including before and after alignment and ornament extraction:
doi.org/10.20383/103...
Reposted by Kjetill S Jakobsen
rmwaterhouse.bsky.social
Earth BioGenome Project Frontiers Online Forum Deep Dive on September 18, 2025 (07:00 PT | 16:00 CEST), where we will discuss the article and chart next steps for the field. 📌 Register here: events.frontiersin.org/earth-biogen...
Reposted by Kjetill S Jakobsen