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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡
@klausenhauser.bsky.social
2K followers 2K following 880 posts
🇨🇦🇭🇰 @EPFL_en protein production + structure facility 🇨🇭| ex @ubc @uwaterloo @unige_en | here for #proteins #structuralbiology #xray #cryoem #plants #mountains #politics #transit #urbanism 🐱🐈 staying for the #hottakes | My views here🧪🧬🌱🔬🏳️‍🌈
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Reposted by Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡
mitsenkov.bsky.social
Maxim Tsenkov @mitsenkov.bsky.social · 1d
The latest #AlphaFold DB update is out!

We synchronised with UniProt release 2025_03, predicted protein isoforms across all species, and provide MSAs used to generate each prediction.

Proud of the team at the PDBe for the hard work that went into this. Grateful to play my part in it!
ebi.embl.org
EMBL-EBI @ebi.embl.org · 1d
We’re renewing our collaboration with Google DeepMind!

We'll keep developing the AlphaFold Database to support protein science worldwide 🎉

To mark the moment we’ve synchronised the database with UniProtKB release 2025_03.

www.ebi.ac.uk/about/news/t...

🖥️🧬 #AlphaFold
@pdbeurope.bsky.social
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 1d
There’s always enough PDL1, EGFR… it’s the new lysozyme
klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 1d
Yes I think they’re just mining from the data they have from previous competitions and also from papers to retest. But it’s still nice to see. I guarantee many of these designs would’ve never been tested again especially in a different lab.
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 2d
Have heard this being suggested by many, but haven’t seen anything real until now
klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 2d
Hmmm a library of protein designs all assessed for binding on the same platform. All with sequences, both positive and negative data. Makes for much better comparison than those made via paper claims.

proteinbase.com
Proteinbase
The home of protein design data
proteinbase.com
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 13d
Shiver
Reposted by Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡
conradhackett.bsky.social
Conrad Hackett @conradhackett.bsky.social · 13d
NEW: In 2025, 43% of young American adults regularly get their news from TikTok.
www.pewresearch.org/short-reads/...
A bar chart showing that TikTok is increasingly a place for news, especially among young U.S. adults. Adults ages 30 to 49 have also increasingly been getting news on TikTok: A quarter now say they do so regularly, up from just 2% five years ago. Much smaller shares of adults ages 50 to 64 and 65 and older say they regularly get news there (10% and 3%, respectively, as of this year).
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Reposted by Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡
mclellanlab.bsky.social
Jason McLellan @mclellanlab.bsky.social · Jun 18
Our latest preprint is now available doi.org/10.1101/2025...! Led by my postdoc, Luqiang Guo @luqiang.bsky.social, we determined a ~2.4 A resolution structure of the hantavirus glycoprotein tetramer on the surface of VLPs. Also determined structures of dimers of tetramers and Fab-bound tetramers.
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Reposted by Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡
computingcaitie.bsky.social
Caitie McCafferty @computingcaitie.bsky.social · 15d
I am excited to share our new preprint on the CAGE complex, a mysterious hollow protein complex that I first saw years ago while surveying Tetrahymena ciliary lysate www.biorxiv.org/content/10.1... #cilia #protistsonsky 🧬🧪
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Reposted by Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡
dudinlab.bsky.social
Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 15d
Be our neighbour !
centriolelab.bsky.social
Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 23d
Be our new colleague! 🎉
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.

👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch

Please feel free to share this opportunity with your network.
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 15d
tell that to my other neighbour where I can hear their laundry machine turn and shake
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 15d
I even take baths at night sometimes ☠️ no no no no no
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 15d
not in geneva!
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 15d
i just checked, its 2100. www.ge.ch/bruit-voisin...

Ive been living my whole life wrong for the past 10 years 😂
klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 15d
no the correct answer is 2100 with the green check. I put 2200 with the blue dot
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 15d
Rejected for nationality because I make noise after hours. 😭
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 17d
But I think these are my fave varieties
‘just marries’, ‘pink suffision’, ‘café au lait’
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 17d
Long weekend dump. Torn between going to the 🏔️ or my garden. What did I choose?….
Tomatoes the size of my full extended palm Salsa batch #2 of the year A bouquet of dahlias View of dahlia plot
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 18d
I’m only on epi 4! But I feel similar ways. I still don’t understand this interplay of cyborg, synths and hybrids
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Reposted by Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡
esqueer.net
Alejandra Caraballo @esqueer.net · 20d
Heritage Foundation has released an absolutely insane policy proposal to label all trans people as domestic terrorists. It uses completely made up instances of terrorism and made up statistics but facts don't matter to them.

They want us all eradicated.
Page 1: Flyer from The Heritage Foundation Oversight Project titled “Transgender Ideology-Inspired Violent Extremism (TIVE): Background and FAQs on Need for an FBI Domestic Terrorism Designation.” The page defines “Transgender Ideology” and “TIVE,” outlining beliefs allegedly associated with them. It claims such ideology justifies violence against opponents or frames opposition as violence. The text references the alleged assassination of Charlie Kirk, urging the FBI to classify TIVE as domestic terrorism. Page 2: Continuation of flyer with a section titled “Recent Instances of TIVE-Motivated Acts of Domestic Terrorism.” Lists multiple violent events from 2018 to 2025, attributing them to transgender ideology. Includes mugshots of two alleged attackers. Followed by a “Frequently Asked Questions and Key Terms” section, addressing whether transgender people are terrorists, comparing TIVE with “Nihilistic Violent Extremism,” and discussing FBI designations. Page 3: Flyer continues with questions about Antifa and FBI terrorism classifications. States that Antifa and TIVE are separate categories. Lists ways the FBI classifies domestic terrorism and identifies typical characteristics of “TIVEs,” such as targeting Christians, mental illness, and online radicalization. Includes images: a “Trans Antifa” logo, a pink-blue-white-striped slogan image reading “Protect Their Right to Exist,” a photo of Audrey Hale with a firearm, and a close-up of a magazine with the words “Where is your God?” Page 4: Section titled “Terminology Used by TIVE.” Defines terms including cisgender, deadnaming, Gillick competence, misgendering, “Right to Exist,” “Trans genocide,” and a phrase “You either have a live boy or dead girl, you choose.” Each is presented as terminology used in or associated with TIVE. Page layout is text-heavy, no additional graphics.
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 18d
Now they just need to get a HK cafe style food trend happening
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 18d
I was just listening to the soundtrack yesterday! And I just applied this today. What’s going on!!
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 21d
Shouldn’t have been that difficult… found press release before the preprint.. and that link I had to find on X
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 21d
found it! www.biorxiv.org/content/10.1...
Generative design of novel bacteriophages with genome language models
Many important biological functions arise not from single genes, but from complex interactions encoded by entire genomes. Genome language models have emerged as a promising strategy for designing biol...
www.biorxiv.org
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klausenhauser.bsky.social
Kelvin Lau @klausenhauser on 🙅‍♂️🐘🪡 @klausenhauser.bsky.social · 21d
anyone can find the preprint? I only found : arcinstitute.org/news/hie-kin...
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