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Lydia Lynch @lydialynch.bsky.social · 7d

Super brilliant talk by Shruti @drshrutinaik.bsky.social visiting us in Princeton today 🐅 @princetonmolbio.bsky.social on new frontiers for the immune system in health, and co-opted in disease

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Lydia Lynch @lydialynch.bsky.social · 19d

He’s a doctor 🎉 Congratulations Dr Martin Brennan @princetonmolbio.bsky.social @tbsi-tcd.bsky.social We’re going to miss him so much! Onwards and upwards

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Reposted by Lydia Lynch

Science Blog @scienceblog.com · Mar 18

Diabetes drug metformin causes weight loss by triggering the production of an "anti-hunger" molecule called lac-phe, also produced after vigorous exercise. #Metformin #WeightLoss #LacPhe #GutBrainConnection

Metformin's Weight Loss Effect Linked to "Anti-Hunger" Molecule Produced During Exercise

A new study conducted by researchers at Stanford Medicine and Harvard Medical School has found that the diabetes medication metformin causes weight loss

scienceblog.com

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Lydia Lynch @lydialynch.bsky.social · Jul 29

And thank YOU Amanda for all your help on this team project for many years! It takes a village (to publish these days)

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Lydia Lynch @lydialynch.bsky.social · Jul 28

And funding from @nih niaid @themarkfdn.bsky.social @ludwigcancer.bsky.social @irishresearchcouncil

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Lydia Lynch @lydialynch.bsky.social · Jul 28

Special thanks to @hannahprendeville.bsky.social @britta, @clairemci.bsky.social @roisin @ayantu and collaborators @edchouchani, @marciahaigis, @susankaech @evannamills

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Lydia Lynch @lydialynch.bsky.social · Jul 28

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...

The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism

This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.

www.nature.com

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Lydia Lynch @lydialynch.bsky.social · Jul 25

Happy summer from Princeton. Feeling very lucky ☘️🐅

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Reposted by Lydia Lynch

Lisa Situ @lisasitu.bsky.social · Jun 11

ICYMI: Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer, a #ResearchWatch summary of a new study by @karen--s.bsky.social, @lydialynch.bsky.social, and colleagues at @ludwigcancer.bsky.social @princetonmolbio.bsky.social

aacrjournals.org/cdnews/news/...

Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer

Major Finding: Lipids derived from ascites are taken up by NK cells and drive NK cell dysfunction in ovarian cancer. Concept: Polar lipids such as phosphatidylcholine disrupt NK plasma membrane order ...

aacrjournals.org

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Reposted by Lydia Lynch

γδ T cell Forum @forum-gd.bsky.social · Jun 4

www.nature.com/articles/s41...

@jkuball.bsky.social @sotnom.bsky.social @lydialynch.bsky.social @labminguet.bsky.social

Disrupting the balance between activating and inhibitory receptors of γδT cells for effective cancer immunotherapy

Nature Reviews Cancer - In this Review, Beringer and colleagues highlight how future strategies for developing immunotherapies using γδT cells and their receptors will depend on creating...

www.nature.com

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Reposted by Lydia Lynch

Harvard T.H. Chan School of Public Health @hsph.harvard.edu · May 16

With nearly all of Harvard Chan School’s direct federal grants terminated, we are relying on philanthropy to power our research and support our educational programs. Every gift, regardless of size, advances our vision of health, dignity, and justice for every human. Support our work: hsph.me/whygive

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Lydia Lynch @lydialynch.bsky.social · May 12

Our paper @sciimmunology.bsky.social shows certain lipids are responsible for the immunosupression of ascites & propose blocking lipid uptake thru SCARB1 may help immunotherapy in ovarian cancer. Wonderful to collaborate with Donal Brennan, Marcia Haigis & super postdoc @karen--s.bsky.social

Ludwig Cancer Research @ludwigcancer.bsky.social · May 9

Researchers led by Ludwig Princeton’s @lydialynch.bsky.social report that certain fats in ascites fluid—which accumulates as ovarian cancer spreads from the ovaries into the abdomen—sabotage anti-tumor immune responses and show how this effect might be blocked for immunotherapy. bit.ly/4jGuUtU

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Reposted by Lydia Lynch

Ludwig Cancer Research @ludwigcancer.bsky.social · May 9

Researchers led by Ludwig Princeton’s @lydialynch.bsky.social report that certain fats in ascites fluid—which accumulates as ovarian cancer spreads from the ovaries into the abdomen—sabotage anti-tumor immune responses and show how this effect might be blocked for immunotherapy. bit.ly/4jGuUtU

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Lydia Lynch @lydialynch.bsky.social · May 2

Wooo congrats Kivanc! Totally deserving winner of this great community award 🏆 Sad to miss a great meeting!

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Lydia Lynch @lydialynch.bsky.social · Apr 24

A beautiful day in Princeton @princeton.bsky.social to host our Ludwig Distinguished speaker Dr Kivanc Birsoy from Rockefeller @ludwigcancer.bsky.social

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Lydia Lynch @lydialynch.bsky.social · Apr 24

Delighted to have taken part in this project that was published today led by Tomas Ryan’s lab @tjryan.bsky.social @tcddublin.bsky.social @tbsi-tcd.bsky.social ….. mice remember cold 🐭📝❄️

Princeton MolBio @princetonmolbio.bsky.social · Apr 23

Immunologists and neuroscientists collaborate to show experience of cold temps leaves a lasting impression on the brain. In Nature paper today by labs of Princeton's Lydia Lynch @lydialynch.bsky.social and Trinity College Dubin's Tomás Ryan @tjryan.bsky.social. molbio.princeton.edu/news/2025/co...

Cold comforts: animals form memories about temperature

The experience of cold temperatures leaves a lasting impression on the brain, according to a new study published April 23, 2035 in the journal Nature. The study was conducted through a collaborative e...

molbio.princeton.edu

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Reposted by Lydia Lynch

Dr. Jessie Christiansen @aussiastronomer.bsky.social · Mar 9

HANG IT IN THE LOUVRE.

(President of Mexico on International Women’s Day)

Claudia Scheinbaum, President of Mexico, in the centre of the image in a purple dress on International Women’s Day, 2025. A search around on google fails to turn up an image credit unfortunately, I found it on Reddit: https://www.reddit.com/r/AccidentalRenaissance/s/MGhF9O80FL

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Reposted by Lydia Lynch

Jack Iwashyna @iwashyna.bsky.social · Mar 8

NIH budget: $ 48b
Musk wealth: $351b

Both are mostly funded by your tax dollars

But only one might save your life
.
.
.
.
Sources:
www.nih.gov/about-nih/wh...

Search results: elon musk net worth g.co/kgs/6c8YEuB

@standupforscience.bsky.social

Google Search

g.co

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Lydia Lynch @lydialynch.bsky.social · Mar 7

Thank you to our colleagues in France ❤️🇫🇷❤️🇺🇸❤️ #standupforscience

Anonymous @youranoncentral.bsky.social · Mar 6

France is showing up, will you? #3E #USProtests #March7Science #StandUpForScience

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Lydia Lynch @lydialynch.bsky.social · Mar 7

Thank you to our colleagues @pasteur.fr Paris 🇫🇷🥼🧪 #standupforscience

Institut Pasteur Education @pasteuredu.bsky.social · Mar 7

📢Aujourd'hui l'Institut Pasteur se mobilise pour la science, l'inclusion & l'avenir du savoir avec l'organisation du symposium «Excellence Scientifique : et si l'inclusion était la clé ?» en écho avec la Journée Internationale des Droits des Femme & la participation au mouvement #StandUpForScience !

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Lydia Lynch @lydialynch.bsky.social · Mar 7

Thank you to our colleagues in Geneva #standupforscience

Angela Huttner @angelahuttner.bsky.social · Mar 7

Good morning, US colleagues!

In Switzerland, we'll speak up for you and #science everywhere!

#Standupforscience walkout in #Geneva

So many came even with little notice ☺️

We'll stay with you, and we'll only grow

🙏🏼 to the great leadership of #unige

#ScienceSky #MedSky #EpiSky

Photo shows a Swiss scientist holding a flyer for Stand Up for Science.

Photo shows Swiss scientists holding flyers for Stand Up for Science.

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Reposted by Lydia Lynch

Eric Topol @erictopol.bsky.social · Mar 1

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...

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Lydia Lynch @lydialynch.bsky.social · Feb 27

So happy to have @aiinglim.bsky.social as a colleague at Princeton! Her immunology is so exciting and original 😍 Great talk at Princetons ‘Quantitative Immunology’ Symposium today @princetonmolbio.bsky.social

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Reposted by Lydia Lynch

E John Wherry @ejohnwherry.bsky.social · Feb 26

First measles death in Texas. Unfortunately, not surprising. Number of cases likely to increase and we may see more deaths. A tragic, preventable death of a school aged child. But the outbreak is called "not so unusual" by RFK. Simply not true. This is both unusual AND preventable. #vaccineswork

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Lydia Lynch @lydialynch.bsky.social · Feb 24

Congratulations to the amazing @karen--s.bsky.social ! And many thanks to @irishcancersociety and Prof Donal Brennan in @ucddublin.bsky.social for continued collaboration on gynaecological cancer research

Karen Slattery @karen--s.bsky.social · Feb 24

I was honored to recieve the Translational Project of the Year Award at the Irish Cancer Society Awards last week! Thanks so much to the ICS for funding and acknowledging this work, and to @lydialynch.bsky.social for all of the support over the years! 😊🥰

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