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mchatzigeorgiou.bsky.social
Marios Chatzigeorgiou
@mchatzigeorgiou.bsky.social
150 followers 340 following 5 posts
Neurobiologist, Group Leader @msarscentre.bsky.social https://www.chatzigeorgioulab.com/
www.chatzigeorgioulab.com
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mchatzigeorgiou.bsky.social
Marios Chatzigeorgiou @mchatzigeorgiou.bsky.social · Apr 22
Super excited for our new preprint on the role of tissue mechanics on the neurophysiology and behavior of Ciona. A tour de force by @midlangandreas.bsky.social and other lab members combining tension sensors, calcium imaging, optogenetic tools and of course behavior. More to come soon.
msarscentre.bsky.social
Michael Sars Centre @msarscentre.bsky.social · Apr 22
Congratulations to the Chatzigeorgiou lab @mchatzigeorgiou.bsky.social for a new preprint 🤩👏 @midlangandreas.bsky.social and team studied the mechanical forces at play during #Ciona postembryonic development, and found links to larval chemosensation and settlement behavior 🧪 Read the article ⤵️
Mechanics regulate the postembryonic developmental maturation and function of sensory neurons in a pre-vertebrate chordate
Physical forces are emerging as important contributors to a wide diversity of biological processes across multiple scales and contexts. The development of the nervous system is infuenced by mechanical...
www.biorxiv.org
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Reposted by Marios Chatzigeorgiou
oceanetourniere.bsky.social
Océane Tournière @oceanetourniere.bsky.social · 1d
Still can’t quite believe it 💫 I’ve received the L’Oréal-UNESCO For Women in Science “Jeunes Talents” France 2025 award!
I’m so deeply honored — this recognition means so much to me, both as a scientist and as a woman who loves research. 💙🔬 1/3
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Reposted by Marios Chatzigeorgiou
micromotility.bsky.social
Kirsty Wan @micromotility.bsky.social · 3d
Very sad to hear that Sir John Gurdon, former Master of Magdalene College, has passed away at the age of 92. www.cam.ac.uk/research/new...

Here is a powerful reminder that you should never give up on your dreams.
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Reposted by Marios Chatzigeorgiou
msarscentre.bsky.social
Michael Sars Centre @msarscentre.bsky.social · 23d
Huge congratulations to postdoc Guillaume Poncelet @guillaumeponcelet.bsky.social who was awarded a UiB Early Idea innovation grant 🤩🎉 Inspired by his work in the @lionlchristiaen.bsky.social lab, he will be developing a new product derived from naturally occurring compounds 🔬 Read more below ⤵️
Michael Sars Centre researcher awarded UiB Idé innovation grant
Guillaume Poncelet, postdoctoral researcher in the Christiaen group, will receive funding from the UiB Idé innovation program to develop a novel product inspired by marine life.
tinyurl.com
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Reposted by Marios Chatzigeorgiou
skatsanevakis.bsky.social
Stelios Katsanevakis @skatsanevakis.bsky.social · 23d
Our Editorial concludes a Research Topic with 26 insightful articles on how #ecosystems respond to human pressures & #ClimateChange: www.frontiersin.org/journals/mar...

Explore the full collection: www.frontiersin.org/research-top...

#MarineScience #Conservation #Biodiversity #MarineEcology
🧪🌍🌐🌊
Frontiers | Understanding the Response of Ecosystems to Increasing Human Pressures and Climate Change – Management Options
The human footprint on the world's oceans has grown significantly in recent years, exerting immense pressure on marine ecosystems and leading to a decline in...
www.frontiersin.org
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rnadoctor.bsky.social
Matteo Ruggiu, PhD @rnadoctor.bsky.social · 24d
This was a collaborative project with Alberto Stolfi at GeorgiaTech and @lionlchristiaen.bsky.social at @nyu.edu, @msarscentre.bsky.social, and @unibergen.bsky.social .

Alberto also created a song for this paper, in the style of 80s hard rock. Check it out 🔈
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Reposted by Marios Chatzigeorgiou
lionlchristiaen.bsky.social
Lionel Christiaen, PhD (he/him/his) @lionlchristiaen.bsky.social · 25d
Another tour-de-force paper led by Bluesky-free Alberto Stolfi, who pushed it through the finish line in his lab at Georgia Tech 🙌🏻🙏🏻 From transcription to alternative RNA splicing, AchR aggregation and neuromuscular junction formation #Ciona neurodevelopment at its best 🤩 @msarscentre.bsky.social
plosbiology.org
PLOS Biology @plosbiology.org · 25d
Neuron-specific splicing of Agrin by Nova is essential for AChR clustering at the NMJ. @rnadoctor.bsky.social @lionlchristiaen.bsky.social &co show that this pathway is conserved in tunicates & that the transcription factor Ebf is a key activator of Nova expression @plosbiology.org 🧪 plos.io/3VhTwig
Top left: Two-color double ISH of Nova (green) and Islet (magenta) showing co-expression in the bilaterally symmetric Motor Neuron 2 (MN2) pair of cells (arrows). Note that Nova mRNA distribution appears more nuclear than Islet in these cells at this stage. Top right: Summary model diagram of a conserved Nova-Agrin-Lrp4 pathway for AChR clustering in Ciona. Upper panel: Summary of conserved pathway, and previously unidentified Ebf-Nova regulatory connection identified in Ciona. Lower panel: Model of proposed mechanism for Ciona Nova-dependent alternative Agrin splicing via binding of KH1 and KH2 domains to two YCAY-rich NISEs identified in the intron 3′ to the Z exons (though not known in what exact orientation or configuration). Inhibitory effect of KH3 domain is relieved by the N- and C-termini. Diagram not drawn to scale. Bottom: Neural-specific CRISPR-mediated disruption of Agrin using sgRNAs results in loss of Acetylcholine receptor A1::GFP clusters (AChRA1::GFP, green) in tail muscles, driven by the Tbx6-r.b promoter. Motor neuron axons labeled by VAChT > Unc-76::mCherry in magenta.
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Reposted by Marios Chatzigeorgiou
skatsanevakis.bsky.social
Stelios Katsanevakis @skatsanevakis.bsky.social · 24d
New preprint! 🎶🌊 We built a low-cost (€50) passive acoustic toolkit for underwater recordings—robust, DIY, and ideal for #CitizenScience & education. Testing shows strong potential for large-scale #soundscape #monitoring.
www.preprints.org/manuscript/2...
#MarineEcology #hydroacoustics 🧪🌍🌐
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Reposted by Marios Chatzigeorgiou
evodevogenomeub.bsky.social
EvodevogenomeUB- Cañestro’s lab @evodevogenomeub.bsky.social · Sep 9
Congrats Esteve 👏🏻👏🏻 for your excellent defense of your TFG studying how marine noise contamination affects #Oikopleura, #deuteronoise project cosupervised by @evadevo.bsky.social @esteeve.bsky.social @geneticsub.bsky.social @irbio-ub.bsky.social @ub.edu
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thibautbrunet.bsky.social
Thibaut Brunet @thibautbrunet.bsky.social · Sep 9
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Flagellar gliding in choanoflagellates
Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates, the closest relatives of animals. Under mild confinement, choanoflagellate move over surfaces without cell deformat...
www.cell.com
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Reposted by Marios Chatzigeorgiou
msarscentre.bsky.social
Michael Sars Centre @msarscentre.bsky.social · Sep 4
"A reminder of why I fell in love with biology in the first place" 🔬✨ This summer, PhD candidate Max Jordi Makem Pekouankouang from the @lionlchristiaen.bsky.social lab participated in the Embryology course at @mblscience.bsky.social. He shares how this experience enriched his approach to science ⤵️
A transformative embryology summer course
This summer, PhD candidate Max Jordi Makem Pekouankouang from the Christiaen group at the Michael Sars Centre attended the prestigious Embryology summer course at the Marine Biological Laboratory in W...
shorturl.at
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Reposted by Marios Chatzigeorgiou
andrewclin.bsky.social
Andrew Lin @andrewclin.bsky.social · Sep 1
Excited to share our latest work - expressing the bacterial sodium channel in fly Kenyon cells surprisingly *decreases* their excitability, thanks partly to decreased endogenous sodium channels. This prevents learning and decreases odor-evoked calcium influx doi.org/10.1113/JP28...
Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells
Abstract figure legend: We tested the effects of expressing the bacterial voltage-gated sodium channel NaChBac in the Kenyon cells of the Drosophila memory centre, the mushroom body. NaChBac expressi...
doi.org
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Reposted by Marios Chatzigeorgiou
ulrichtechnau.bsky.social
ulrichtechnau.bsky.social @ulrichtechnau.bsky.social · Aug 29
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins. www.nature.com/articles/s41...
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Reposted by Marios Chatzigeorgiou
micromotility.bsky.social
Kirsty Wan @micromotility.bsky.social · Aug 23
Complex behaviour is not limited to animals! Here we map the entire spectrum of waveforms dynamics on a quadriflagellate single cell with 4x 70um (!) #cilia, to a low dimensional behavioural manifold with surprising structure! #protistsonsky

All revealed in our new preprint doi.org/10.1101/2025...
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Reposted by Marios Chatzigeorgiou
msarscentre.bsky.social
Michael Sars Centre @msarscentre.bsky.social · Aug 21
Congratulations @appygenetics.bsky.social on a new preprint 🤩 🧪 Read the whole paper below ⤵️
appygenetics.bsky.social
Chourrout lab @appygenetics.bsky.social · Aug 18
Check the last preprint from @simonhenriet.bsky.social & colleagues‬. By studying appendicularians, they revealed the events that permitted non-canonical splicing in these organisms:

. Duplication & divergence of U2AF splicing factors
. Gain & loss of chemical modifications on the spliceosomal RNA
Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and re-patterning of snRNA m6A modification
In eukaryotes, splicing is a critical step of gene expression that produces transcripts competent for protein synthesis by removing introns from pre-mRNA. The spliceosome defines target splice sites b...
www.biorxiv.org
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emclaereboudt.bsky.social
Emily Claereboudt @emclaereboudt.bsky.social · Aug 20
🌊🧪 Big day at #chemecol2025!
I presented my talk:
“Chemical cues & larval behaviour in the tunicate Ciona intestinalis 🪸✨

I had the pleasure of chairing the Aquatic Chemical Ecology session — featuring amazing talks on annelids, cnidarians, oysters, and red algae. 🌿🦪🪼🪱
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Reposted by Marios Chatzigeorgiou
amunts.bsky.social
Alexey Amunts @amunts.bsky.social · Jul 7
Our new preprint: how photoprotection is spatially coordinated with energy metabolism. Photosystem I is major source of radicals. We report EM structure of PSI in complex with superoxide dismutase SOD: direct link between energy conversion & oxidative stress defence
www.biorxiv.org/content/10.1...
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Reposted by Marios Chatzigeorgiou
focalplane.bsky.social
FocalPlane @focalplane.bsky.social · Jun 13
🔬Our preprint list is now up on FocalPlane.
This week we focus on new tools and techniques in imaging. Let us know if we are missing any recent preprints that you've enjoyed reading.
focalplane.biologists.com/2025/06/13/m...
Microscopy preprints – new tools and techniques in imaging - FocalPlane
Microscopy preprints – new tools and techniques in imaging - News
focalplane.biologists.com
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Reposted by Marios Chatzigeorgiou
focalplane.bsky.social
FocalPlane @focalplane.bsky.social · Jun 27
📢Our latest preprint list is now up on FocalPlane.
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...
Microscopy preprints - applications in biology - FocalPlane
Microscopy preprints - applications in biology - News
focalplane.biologists.com
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predator-smarts.bsky.social
Eamonn Wooster @predator-smarts.bsky.social · Jun 29
The Predatory Intelligence Hypothesis. Happy to share this new preprint about how predator-prey interactions drive cognitive evolution and maintain cognitive variation.

ecoevorxiv.org/repository/d...
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zolotarg.bsky.social
Grisha Zolotarov 🐙🇺🇦 @zolotarg.bsky.social · Jun 29
Suddenly ran into a sketch I’ve made for the placozoan peptidergic cells paper:

www.cell.com/cell/fulltex...
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Reposted by Marios Chatzigeorgiou
jekely.biologists.social.ap.brid.gy
Gaspar Jekely @jekely.biologists.social.ap.brid.gy · Jun 30
In our new preprint we describe the synaptic #connectome of the nerve net in the ctenophore gravisensory organ. https://www.biorxiv.org/content/10.1101/2025.06.26.661250v1 #biology #neuroscience #ctenophore #vem
Volume rendering of the ctenophore aboral organ reconstructed by volume EM, showing the gravisensory balancers and the four quadrants.
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Reposted by Marios Chatzigeorgiou
amunts.bsky.social
Alexey Amunts @amunts.bsky.social · Jun 30
Excited to contribute to the Mitoribosome collaborative study led by @wredenberglab.bsky.social in @natcomms.nature.com🎉 "The mitochondrial methylation potential gates mitoribosome assembly"
The assembly starts before the completion of the rRNA gene cluster processing🧵
www.nature.com/articles/s41...
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Reposted by Marios Chatzigeorgiou
msarscentre.bsky.social
Michael Sars Centre @msarscentre.bsky.social · Jun 17
The 4th edition of the Michael Sars Symposium was a success 🤩 A big thank you to our fantastic speakers, engaged audience and organizing team ✨ Have a look below for a throwback to the #MSS2025 highlights! 📸⤵️
Exploring evolution across scales at the Michael Sars Symposium 2025
The fourth edition of the Michael Sars Symposium brought together experts from a variety of research fields within biology, all united by a common theme – evolution.
tinyurl.com
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ncmbm.bsky.social
Norwegian Centre for Molecular Biosciences and Medicine (NCMBM) @ncmbm.bsky.social · Jun 30
🔬 Research programmes should align with one or both of our scientific pillars:

- Molecular and cellular basis of disease and therapy

- Computational biology, functional genomics, and systems biology

🗓️ Deadline: 8 September 2025

👉 Find out more and apply: tinyurl.com/yc8bb4f7
Group Leader (282908) | University of Oslo
Job title: Group Leader (282908), Employer: University of Oslo, Deadline: Monday, September 8, 2025
tinyurl.com
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ncmbm.bsky.social
Norwegian Centre for Molecular Biosciences and Medicine (NCMBM) @ncmbm.bsky.social · Jun 30
📣 We’re recruiting 1-2 Group Leaders! NCMBM is looking for early-career researchers ready to establish their independent research groups!

🧬 With an attractive start-up package, help us shape the future of molecular biosciences and medicine in 🇳🇴 and be part of the @nordicembl.bsky.social!
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