Melike Lakadamyali
@melikel.bsky.social
1.7K followers
780 following
17 posts
Professor, Physiology Department, Perelman School of Medicine, University of Pennsylvania. https://www.lakadamyali-lab.com
Super resolution microscopy, single molecule biophysics, microtubules, organelles, nucleus and chromatin
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Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Eric Joyce
@ericjoyce.bsky.social
· Aug 14
Mechanistic and Epigenetic Partitioning of Lamina-Associated Chromatin Revealed by a Genome-Wide Imaging Screen
The nuclear periphery is a key site for heterochromatin organization in eukaryotic cells, where lamina-associated domains (LADs) promote transcriptional repression and genome stability. Despite their ...
www.biorxiv.org
Melike Lakadamyali
@melikel.bsky.social
· Aug 10
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Ellenberg Lab
@ellenberglab.bsky.social
· Jul 21
Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ - Nature Communications
A nanoscale 3D DNA tracing workflow visualizes Cohesin-dependent loops in single, structurally well-preserved cells. Computer simulations based on the tracing data give further insight into how Cohesi...
www.nature.com
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
Felix Campelo
@felixmendu.bsky.social
· Jul 4
Intracellular mechanics and organelle mechanobiology
Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…
meetings.embo.org
Reposted by Melike Lakadamyali
Reposted by Melike Lakadamyali
SMLMS 2025
@smlm-symposium.bsky.social
· Jun 11
Reposted by Melike Lakadamyali