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Melissa Gammons @melissa-gammons1.bsky.social · Jun 6

Thanks and yes, I meant to tag @cancerresearchuk.org for funding, apologies 😅

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Melissa Gammons @melissa-gammons1.bsky.social · Jun 3

Scientific tweetorial to follow…

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Melissa Gammons @melissa-gammons1.bsky.social · Jun 3

Finally a massive thanks to all coauthors who aren’t on this platform but all helped get this over the line despite retirement, pregnancy/new children and surgery! It was huge endeavour.

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Melissa Gammons @melissa-gammons1.bsky.social · Jun 3

The review process at @natcomms.nature.com was thorough and thanks to the exceptional reviewers (all 5 of them) for their in depth review which challenged us and ultimately improved the manuscript

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Melissa Gammons @melissa-gammons1.bsky.social · Jun 3

Thanks to funding from the @wellcometrust.bsky.social, @cruk-mi.bsky.social and @mrclmb.bsky.social core support

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Melissa Gammons @melissa-gammons1.bsky.social · Jun 3

This project spanned 7-years starting in the Bienz lab @mrclmb.bsky.social and finishing in my own lab @thecimr.bsky.social, with huge thanks to both institutes for support in administration and core facilities

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Melissa Gammons @melissa-gammons1.bsky.social · Jun 3

Excited to share our recent paper on the Wnt signalosome www.nature.com/articles/s41...

Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor - Nature Communications

Gammons et al. describe how the clustering of the Wnt receptor complex in clathrin-coated locales allows Axin and GSK3 to dock at adjacent tails of the LRP6 co-receptor to assemble a signalosome that ...

www.nature.com

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Melissa Gammons @melissa-gammons1.bsky.social · Jun 3

So many congratulations! And super excited to be lab neighbours 😀 well done x

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Melissa Gammons @melissa-gammons1.bsky.social · Mar 23

Congrats @abelljonny.bsky.social and colleagues 👏

David Kuster @rnadavid.bsky.social · Mar 23

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes!

Annexin A11 tethers RNP granules to membranes in a Ca2+ dependent manner.

@abelljonny.bsky.social, @michael-e-ward.bsky.social, et al.

www.nature.com/articles/s41...

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes - Nature Communications

Nixon-Abell et al. show that ANXA11 condensation on lysosomal membranes causes a coupled phase transition of the underlying lipids and mechanical stiffening of the overall ensemble involved in RNP gra...

www.nature.com

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Reposted by Melissa Gammons

Cambridge Institute for Medical Research @thecimr.bsky.social · Mar 4

We loved hosting the latest cohort of students to our ISAC/M programme over half term, along with @mrc-mbu.bsky.social and St Catharine's College. What a fantastic group of young people! www.cimr.cam.ac.uk/news/inspiri...

Inspiring Scientists at CIMR-MBU 2025 | Cambridge Institute for Medical Research

During February half term we welcomed the latest cohort of sixth-form students to our Inspiring Scientists programme (ISAC/M), run in collaboration with the MRC MBU and St Catharine’s College.

www.cimr.cam.ac.uk

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Reposted by Melissa Gammons

Nivedita Sarveswaran @neuroniv.bsky.social · Feb 28

Rare Disease Day honours 300 million extraordinary individuals worldwide. Proud of our work in Geoff Woods’ lab @thecimr.bsky.social to help patients with rare sensory disorders, and hugely grateful for their engagement in research that advances knowledge & healthcare systems to benefit us all.

Zebra striped ribbon pin on lanyard to raise awareness for rare disease patients.

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Reposted by Melissa Gammons

Pierfrancesco Pagella @ppagella86.bsky.social · Feb 26

Hej everyone out there! The registration for this year’s Wnt Signaling Gordon Research Seminar (GRS) and Conference (GRC) is open!
Looking forward to see the whole #WNT community with us in Maine this year!

www.grc.org/wnt-signalin...

2025 Wnt Signaling (GRS) Seminar GRC

The 2025 Gordon Research Seminar on Wnt Signaling (GRS) will be held in Lewiston, Maine. Apply today to reserve your spot.

www.grc.org

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Reposted by Melissa Gammons

WntUK @wntuk.bsky.social · Feb 5

Welcome to #2 of our 'Wnt Researcher of the Week' series where we profile an active researcher in the WntUK network!

Next up is Dr Yeon Kim, PostDoc in the @ianmcgough.bsky.social lab at the @babrahaminst.bsky.social and selected ECR speaker for #WNTUK2025

Yeon's Quickfire Q&A below 🧵1/

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Reposted by Melissa Gammons

WntUK @wntuk.bsky.social · Jan 24

Early bird registration discount may have passed but #WNTUK2025 is still open for standard registration and abstract submission. Still plenty of speaker/poster slots available for all career levels and areas of Wnt signalling.

Abstract deadline Feb 1st and we are just over 8 weeks from the big day!

WntUK @wntuk.bsky.social · Jan 9

What better way to start 2025 than signing up for the #WNTUK2025 meeting on 24th March in @ox.ac.uk sponsored by @oxfordcancer.bsky.social and @cambridgebio.bsky.social. Early bird discount rates only available until Jan 17th and abstract deadline is Feb 1st!

www.cancer.ox.ac.uk/news/oxford-...

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Reposted by Melissa Gammons

Cambridge Institute for Medical Research @thecimr.bsky.social · Jan 23

Great new paper from Jennifer Dickens and @profmarciniak.bsky.social lab

The EMBO Journal @embojournal.org · Jan 15

A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
Jennifer Dickens, Emma Rawlins and collaborators
www.embopress.org/doi/full/10....

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Melissa Gammons @melissa-gammons1.bsky.social · Dec 5

Welcome to Bluesky WntUK! Please follow!

WntUK @wntuk.bsky.social · Dec 4

Please welcome us to BlueSky and give us a follow!

We are newly formed UK scientific society with interests in the structural, molecular and cellular mechanisms of Wnt signalling in development and disease.

We are represented by all four corners of the UK and cover all aspects of Wnt signalling!

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