Özge Özgüç
@oozguc.bsky.social
290 followers 340 following 18 posts
Studying the tiny forces that shape life 🔬 || Postdoc with @xaviertrepat.bsky.social , @maitrejl.bsky.social lab alumna.
Posts Media Videos Starter Packs
Reposted by Özge Özgüç
tomgolde.bsky.social
Check out the preprint of my main work in the lab of @xaviertrepat.bsky.social @IBECBarcelona. Many thanks to all the people involved!
xaviertrepat.bsky.social
New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tomgolde.bsky.social‬ 🙌
@IBECBarcelona
www.biorxiv.org/content/10.1...
Reposted by Özge Özgüç
redpenblackpen.bsky.social
Really just had something like this feeling this afternoon. It’s the high that keeps you coming back for more
Cartoon of a scientist peering through a microscope saying "Whoaah!!!". Title says "The best part of Science is knowing, for a moment, something that nobody else in the world knows."
Reposted by Özge Özgüç
marija-matejcic.bsky.social
On cell extrusion in the #intestine!
After 80 years of observations, we finally took a deeper look thanks to 2D #organoids. We report:

3D #forces, #extrusion still only in the villus even without curvature, #lamellipodia generate 3D force.. and more. Have a look!
www.biorxiv.org/content/10.1...
Reposted by Özge Özgüç
onenimesa.bsky.social
Have you ever thought about inflating tissues?
Or maybe quickly deflating those inflated tissues?

New #EpithelialMechanics pre-print: doi.org/10.1101/2025...
🧵 with pressure control, multiscale buckling, controlled wrinkling
Reposted by Özge Özgüç
xaviertrepat.bsky.social
🚨 Second preprint of the week!

We uncover the multiscale dynamics of active viscoelastic buckling in epithelia.

We harness these mechanical instabilities for synthetic morphogenesis.

Led by @onenimesa.bsky.social 🙌. Theory by Marino Arroyo etal. @ibecbarcelona.eu

www.biorxiv.org/content/10.1...
Reposted by Özge Özgüç
pauguillamat.bsky.social
New preprint out! We show how cellular nematic order can be harnessed to program tissue-wide force fields and guide 3D shape transformations.

The tissue morphogenesis logic, now engineered into living, programmable materials.

www.biorxiv.org/content/10.1...

#ActiveMatter #TissueEngineering
oozguc.bsky.social
highly recommended! 👇
bardinlab.bsky.social
Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included.

training.institut-curie.org/courses/deve...
Reposted by Özge Özgüç
the-node.bsky.social
Featured image with Özge Özgüç: the Node–FocalPlane image competition

Find out more about @oozguc.bsky.social and the story behind "Cell-estial bloom", which won the image competition we organised with @focalplane.bsky.social:
thenode.biologists.com/featured-ima...
A ‘Cell-estial Bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labeled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape.
oozguc.bsky.social
From Turkiye’s Children’s Day to San Jordi in Catalonia, today is all about love, knowledge, and the future.
@ibecbarcelona.eu turned my microscopy image into a bookmark for the occasion🎈

23 Nisan kutlu olsun & Feliç Diada de Sant Jordi!
Reposted by Özge Özgüç
epimechfc.bsky.social
How do hydraulic forces impact critical processes such as tissue integrity, cell fate decisions, and embryo development?

Hydraulics studies how fluids move and exert forces.

Join me in exploring few articles on hydraulics in #EpithelialMechanics
Reposted by Özge Özgüç
kstapornwongkul.bsky.social
We’re looking for PhD students to join the lab! 🧫🧑‍🔬
Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/

‼️Deadline: April 15‼️
PhD Program
Empowering Curious Researchers at the Vienna BioCenter PhD Program Are you a curious and motivated student looking to launch a successful scientific career? Look no further than the Vienna BioCenter P...
training.vbc.ac.at
Reposted by Özge Özgüç
jcellsci.bsky.social
In their Review, Laura Faure, Valeria Venturini @valeriaventurini.bsky.social and Pere Roca-Cusachs discuss the biological contexts of cell mechanical compression, the associated mechanisms and the experimental systems engineered to compress cells in vitro.
journals.biologists.com/jcs/article/...
Cartoon of techniques to apply one-dimensional, in-plane or volumetric cell compression in vitro.
Reposted by Özge Özgüç
the-node.bsky.social
🎉Congratulations to the Top 3 images from the Node–FocalPlane image competition!

1️⃣"Cell-estial bloom" by @oozguc.bsky.social
2️⃣"Dancing actinotroch" by @allancarbal.bsky.social
3️⃣"Who’s active?" by @jupeloggia.bsky.social

thenode.biologists.com/results-from...

@focalplane.bsky.social #biologists100
"Cell-estial bloom" Image from Özge Özgüç:
A ‘Cell-estial bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labelled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape. "Dancing actinotroch" by Allan Carrillo-Baltodano:
Actinotroch larva of a phoronid worm with phalloidin shown in yellow and acetylated tubulin in magenta. Imaged with a Zeiss LSM 800 at 10 x magnification. "Who’s active?" by Julia Peloggia de Castro:
The image depicts a zebrafish embryo at 9 hours post-fertilisation on a lateral view. Cells are stained with MitoTracker, which labels active mitochondria, and cell membranes are labelled in cyan with a EGFP transgenic membrane tag. Image was taken using a 20x objective on a spinning disk confocal microscope.
oozguc.bsky.social
Thank you🥰🥰
oozguc.bsky.social
Whaaat?! Cell-estial Bloom took 1st place in the Node–FocalPlane image competition! 🤯🤯🤯
the-node.bsky.social
🎉Congratulations to the Top 3 images from the Node–FocalPlane image competition!

1️⃣"Cell-estial bloom" by @oozguc.bsky.social
2️⃣"Dancing actinotroch" by @allancarbal.bsky.social
3️⃣"Who’s active?" by @jupeloggia.bsky.social

thenode.biologists.com/results-from...

@focalplane.bsky.social #biologists100
"Cell-estial bloom" Image from Özge Özgüç:
A ‘Cell-estial bloom’ of human induced pluripotent stem cells (hiPSCs) flourishes on a micropatterned island. This image presents a colony of live hiPSCs, with fluorescently labelled Lamin B delineating the nuclear lamina within each cell. Acquired with a Zeiss LSM 880 Airyscan microscope, this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape. "Dancing actinotroch" by Allan Carrillo-Baltodano:
Actinotroch larva of a phoronid worm with phalloidin shown in yellow and acetylated tubulin in magenta. Imaged with a Zeiss LSM 800 at 10 x magnification. "Who’s active?" by Julia Peloggia de Castro:
The image depicts a zebrafish embryo at 9 hours post-fertilisation on a lateral view. Cells are stained with MitoTracker, which labels active mitochondria, and cell membranes are labelled in cyan with a EGFP transgenic membrane tag. Image was taken using a 20x objective on a spinning disk confocal microscope.
oozguc.bsky.social
On my way to to the International Dutch Embryo Model Meeting 2025! 🚆
Excited to dive into the latest advances and have some great discussions.
If you’re around and curious about mechanics in development / mechanically accessible models, come find my poster!!
#IDEMM25
oozguc.bsky.social
My image on display at #Biologists100! 🖼️🔬
So surreal to see “Cell-estial Bloom” showcased in this gallery among so many stunning images! Huge thanks to @LFort8 for the photo!

Also: ✨ it is the last day to vote! ✨
thenode.biologists.com/vote-for-you...
@the-node.bsky.social @focalplane.bsky.social
Reposted by Özge Özgüç
kstapornwongkul.bsky.social
Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!

Thankful for any retweet! 🫶

imba.onlyfy.jobs/job/l6u2m980
Reposted by Özge Özgüç
the-node.bsky.social
Together with @focalplane.bsky.social, we're having an image competition to accompany the #Biologists100 conference.

Thank you everyone who submitted their images. Shortlisting only 15 was tough!

Browse through the gallery and vote for your favourite image:
thenode.biologists.com/vote-for-you...
Vote for your favourite image in the Node–FocalPlane image competition - the Node
Browse through the gallery of the 15 shortlisted images and vote for your favourite image by Wednesday 26 March.
thenode.biologists.com
oozguc.bsky.social
My image is shortlisted and will be displayed at #100Biologists! 🎉

This “Cell-estial Bloom” features LaminB-labeled cells from @alleninstitute.bsky.social glowing in all their fluorescent glory! ✨

All very incredible images—check them out and vote for your favorite (Hope it’s mine! 🤞)!
a colony of live hiPSCs, with fluorescently labeled Lamin B delineating the nuclear lamina within each cell. this maximum intensity projection is enhanced with depth-coded coloring to reveal the captivating three-dimensional landscape.
Reposted by Özge Özgüç
jbwallingford.bsky.social
A woman studies embryos for decades, struggles for funding and respect. She publishes under her husband’s name, until they divorce. A single mother, she moves across an ocean to continue her studies. It all sounds quite modern, until you learn that she also worried she’d be burned as a witch. 🧵 1/15
Reposted by Özge Özgüç
focalplane.bsky.social
Voting is open in our image competition with @the-node.bsky.social.

Thanks to everyone that entered, and congratulations to our final 15. Now it's your turn to pick your favourite!

Look out for our gallery of images at the Biologists @ 100 conference #biologists100.
Vote for your favourite image - FocalPlane
Vote for your favourite image - News
focalplane.biologists.com
Reposted by Özge Özgüç
Reposted by Özge Özgüç
epimechfc.bsky.social
Tissues are dynamic and investigating cellular mechanical states can be crucial for understanding biological processes. But how to do it?

We are @andreasschoenit.bsky.social and @luanger.bsky.social from @bladoux.bsky.social / @rmmege.bsky.social lab highlighting ways to assess tissue stresses.