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petrosligoxygakis.bsky.social
Petros Ligoxygakis
@petrosligoxygakis.bsky.social
1.9K followers 1.3K following 94 posts
Studying host-pathogen interactions, immunity beyond infection. Prof of Immunology at Oxford University and Fellow/Tutor at Hertford College. #Innate Immunity #Drosophila
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · 1d
Huge loss of an absolute scientific giant www.magd.cam.ac.uk/news/profess...
Professor Sir John Gurdon FRS (1933-2025) | Magdalene College
Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.
www.magd.cam.ac.uk
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · 4d
This sounds fun (Synths, Sax & Situationists by Ian Thompson-Roundtable Books) thequietus.com/culture/book...
Demolishing the Outmoded Society: Michel Faber on Situationism and the French Rock Underground | The Quietus
Ian Thompson’s new book Synths, Sax & Situationists explores the legacy of soixante-huit through the music of bands like Cheval Fou, Barricade, Maajun and Fille Qui Mousse. It offers a “vivid” account...
thequietus.com
petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · 9d
Dear Academic Bluesky: my department is recruiting two associate professors. We are a diverse and multidisciplinary biochemistry department (with “biochemistry” defined in the widest possible sense). my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
Reposted by Petros Ligoxygakis
tg128.bsky.social
Tassos @tg128.bsky.social · 11d
Γιατί είναι σημαντικό το πρόσφατα δημοσιευμένο paper με τίτλο Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues 1/6 >
elifesciences.org/articles/99602
Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues
Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.
elifesciences.org
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Reposted by Petros Ligoxygakis
gregpriest.bsky.social
Greg Priest @gregpriest.bsky.social · 13d
Thomas Hunt Morgan was born OTD in 1866.

If you're ever feeling that your work is uending and unedifying, remember that he once said this: "Two years work wasted, I have been breeding those flies for all that time and I've got nothing out of it."

🌱🐋🧪 #HistSTM
Photograph of Morgan's Fly Room at Columbia University, around 1920. American Philosophical Society.
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Reposted by Petros Ligoxygakis
cahirokane.bsky.social
Cahir O'Kane @cahirokane.bsky.social · 13d
59 mutations that suppress neurodegeneration induced by dNmant depletion in a Drosophila screen, including the known pro-degenerative molecule dSarm. Lots of new potential anti-degeneration drug targets to explore here.
biorxiv-neursci.bsky.social
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 13d
A dNmnat-sensitized in vivo platform for unbiased discovery of regulators of neurodegeneration https://www.biorxiv.org/content/10.1101/2025.09.25.678663v1
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Reposted by Petros Ligoxygakis
kranzuschlab.bsky.social
Kranzusch Lab @kranzuschlab.bsky.social · 20d
Cell death plays important roles in antiviral immunity across all kingdoms of life. Great panel discussion in @natsmb.nature.com from leading experts in the field highlight open mysteries in how and why cell death functions:

www.nature.com/articles/s41...
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Reposted by Petros Ligoxygakis
erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 22d
A clever way to activate the immune system against cancer via the STING pathway
www.nature.com/articles/s41...
Tumour-specific STING agonist synthesis via a two-component prodrug system - Nature Chemistry
STING is a promising drug target, but selective activation is necessary for safety and efficacy. Researchers have developed a two-component prodrug system for potent pharmacological activation of STIN...
www.nature.com
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · 23d
Hands down the best record for 2025 yet.
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · Sep 8
Plus Max Roach’s music (very prominent in the soundtrack of the Soundtrack) is incredible!
toddntucker.com
Todd Tucker @toddntucker.com · Sep 8
Highly recommend the Soundtrack to a Coup d’Etat movie to folks teaching international relations and history courses.

It really brings to life the Non Aligned Movement - and connection to US culture and civil rights leaders like Malcolm X.
www.theguardian.com/film/2024/no...
Soundtrack to a Coup d’Etat review – superb study of how jazz got caught between the cold war and the CIA
Johan Grimonprez’s fascinating documentary uses the assassination of DRC prime minister Patrice Lumumba to launch a dizzying look into the politics of jazz in the 1950s and 60s
www.theguardian.com
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · Sep 6
Choano’s are cool!
audeber.bsky.social
Aude Bernheim @audeber.bsky.social · Sep 5
YAYYYY, Immune systems of choano !!!!
Beautiful to see how knowledge about bacterial immune systems illuminate immunology in diverse organisms with the always incredible biochemistry and structural approaches of @kranzuschlab.bsky.social.
Wonderful work @yao-li.bsky.social 👏
kranzuschlab.bsky.social
Kranzusch Lab @kranzuschlab.bsky.social · Sep 5
How can we understand the earliest events in evolution of eukaryotic immunity? @yao-li.bsky.social reports incredible molecular fossils of complete bacterial-like operons in eukaryotes that illuminate how animal immunity was first acquired from anti-phage defense

www.biorxiv.org/content/10.1...
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Reposted by Petros Ligoxygakis
throwingmuses.bsky.social
Throwing Muses @throwingmuses.bsky.social · Sep 2
Athens
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Reposted by Petros Ligoxygakis
labwaggoner.bsky.social
Waggoner Lab @labwaggoner.bsky.social · Sep 4
Waning immunity to Japanese encephalitis virus was associated with increased severity of dengue disease in a cohort of patients from Nepal @stjohnlab.bsky.social www.science.org/doi/10.1126/...
Dengue disease severity in humans is augmented by waning Japanese encephalitis virus immunity
Waning immunity to Japanese encephalitis virus was associated with increased severity of dengue disease in a cohort of patients from Nepal.
www.science.org
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · Sep 2
One of my favourites from the beginning of the 90s: The magnificent Kristin Hersh and her band the Throwing Muses playing Athens yesterday.
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Reposted by Petros Ligoxygakis
cyrilpedia.bsky.social
Thiago Carvalho @cyrilpedia.bsky.social · Sep 1
'Early on in her life, Esther defied societal conventions by pursuing biochemistry, against recommendations from her teachers who believed that a career in science was too difficult for women'
academic.oup.com/genetics/adv...
Pioneer of bacterial genetics: the legacy of Esther Miriam Lederberg
Abstract. Esther Miriam Lederberg's brilliant scientific lifework, from the discovery of phage lambda, bacterial conjugation, and replica plating, provided
academic.oup.com
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Reposted by Petros Ligoxygakis
cyrilpedia.bsky.social
Thiago Carvalho @cyrilpedia.bsky.social · Aug 27
'Here, we identify the immunometabolic crosstalk that generates homocysitaconate, a metabolite formed by homocysteine & itaconate adduction catalyzed by S-adenosyl-L-homocysteine hydrolase. Homocysitaconate increases 152-fold during #inflammation and exhibits anti-inflammatory effects.'
#Immunology
Homocysitaconate controls inflammation through reshaping methionine metabolism and N-homocysteinylation
Lin et al. discover homocysitaconate, an anti-inflammatory metabolite formed during inflammation via AHCY-catalyzed adduction of homocysteine and itaconate. Homocysitaconate is recognized by MARS, ind...
www.cell.com
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · Aug 17
Home
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Reposted by Petros Ligoxygakis
hansonmark.bsky.social
Mark A. Hanson @hansonmark.bsky.social · Aug 14
A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate.

www.philanthropy.cam.ac.uk/give-to-camb...
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · Aug 11
Ανικανότητα για γερό στομάχι…Κονδύλια για «άριστη» έρευνα που προκηρύσσονται ένα χρόνο πριν τελειώσει η προθεσμία του Ταμείου Ανάκαμψης *για δίχρονα πρότζεκτ!* με αξιολογητές που ο καθένας (!) διαβάζει 100 προτάσεις σε 2 μήνες και πανομοιότυπες-AI chatbox αναφορές με ανεξήγητες βαθμολογίες.
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Reposted by Petros Ligoxygakis
birmingham81.bsky.social
Birmingham 81 @birmingham81.bsky.social · Aug 10
Remembering Mark Stewart on his birthday. Here's a playlist of 20 tracks by Bristol's post-punk pioneer
open.spotify.com/playlist/4au...
Remembering Mark Stewart 1960-2023
Playlist · andychislehurst · 20 items · 39 saves
open.spotify.com
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petrosligoxygakis.bsky.social
Petros Ligoxygakis @petrosligoxygakis.bsky.social · Aug 9
What a song. Devastating innocence personified. Somehow it was always hard to listen to this wonderful record from beginning to end without breaking down. Radio on!
remain-in-light.bsky.social
Remain In Light @remain-in-light.bsky.social · Aug 9
That Summer Feeling
youtu.be/wIsfGPsd-SQ?...
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Reposted by Petros Ligoxygakis
teralevin.bsky.social
Tera Levin @teralevin.bsky.social · Aug 5
I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/
www.biorxiv.org/content/10.1...
Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium
Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...
www.biorxiv.org
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Reposted by Petros Ligoxygakis
erictopol.bsky.social
Eric Topol @erictopol.bsky.social · Aug 4
One in 4 people carry one copy of the APOE4 allele, the strongest known genetic risk factor for Alzheimer's disease. We've just learned how that risk is mediated—the immune system
erictopol.substack.com/p/our-braini...
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Reposted by Petros Ligoxygakis
erictopol.bsky.social
Eric Topol @erictopol.bsky.social · Aug 4
The preeminence of the human brain-immune axis is emerging in some unforeseen ways, no less the dawn of an FDA-approved device treatment for autoimmune diseases.
erictopol.substack.com/p/our-braini...
Our Brain—Immune Axis Gets A Jolt
Facts, data and analytics about biomedical matters
erictopol.substack.com
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Reposted by Petros Ligoxygakis
birmingham81.bsky.social
Birmingham 81 @birmingham81.bsky.social · Aug 4
Happy birthday to Vini Reilly. Here are The Durutti Column performing a beautiful version of Royal Infirmary from Circuses and Bread on BBC2's The Review Show in 2011
youtu.be/ZzQe7bjnSrI
The Durutti Column on The Review Show
YouTube video by iamsoftlad
youtu.be
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