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pgtb.bsky.social
PGTB
@pgtb.bsky.social
Genome Transcriptome core facility of Bordeaux. Offering cutting-edge technologies in short and long read sequencing / genotyping to everyone
https://pgtb.fr/
Reposted by PGTB
Do you want to annotate your #pangenome graph and its embedded genome ? Then GrAnnoT is for you !
🖥️🧬 🧪

In the present paper, our PhD student Nina Marthe developed a Python tool, a user friendly one, that allows to
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www.biorxiv.org/content/10.1...
www.biorxiv.org
March 3, 2025 at 9:51 AM
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Comment est-ce que ça pourrait mal se passer ?...
"The universities control the knowledge in our society (...) We have to agressivly attack the universities (...). Fundamental lies that feminism is liberating (...) There is wisdom in what Nixon said, the professors are the enemy "

bryanalexander.org/politics/the...

www.youtube.com/watch?v=0FR6...
J.D. Vance | The Universities are the Enemy | National Conservatism Conference II
YouTube video by National Conservatism
www.youtube.com
March 3, 2025 at 1:29 PM
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🇺🇸 Aux Etats-Unis, Trump et Musk déciment à coups de licenciements la NOAA, vigie de la météo et du climat

En une semaine, l’Agence d’observation océanique et atmosphérique a perdu 10 % de ses 12 000 employés, licenciés sur fond de croisade antiscience du gouvernement américain.

Lire 👇
Aux Etats-Unis, Trump et Musk déciment à coups de licenciements la NOAA, vigie de la météo et du climat
En une semaine, l’Agence d’observation océanique et atmosphérique a perdu 10 % de ses 12 000 employés, licenciés sur fond de croisade antiscience du gouvernement américain. Une manifestation mondiale de chercheurs est prévue le 7 mars.
www.liberation.fr
March 4, 2025 at 7:41 AM
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New preprint is out!
We investigate how well you can call variants directly from genome assemblies compared to traditional read-based variant calling.

Read it here: www.biorxiv.org/content/10.1...
Data & code: github.com/rrwick/Are-r...
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Are reads required? High-precision variant calling from bacterial genome assemblies
Accurate nucleotide variant calling is essential in microbial genomics, particularly for outbreak tracking and phylogenetics. This study evaluates variant calls derived from genome assemblies compared...
www.biorxiv.org
March 3, 2025 at 3:24 AM
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Roche SBX sequencing by expansion preprint out for everyone to read. #NGS #NextGenSequencing
February 25, 2025 at 3:04 PM
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#SBX Fast WGS Clinical Benchmarking: Successfully detects small variants (SNV, Indel), large CNVs (duplications, deletions), and STR expansions in clinical samples, including Fragile X (856 CGG repeats in FMR1), Duchenne MD, and DiGeorge Syndrome. #AGBT25 #AGBT2025 #AGBT @AGBT @Roche
February 25, 2025 at 6:52 PM
New Roche sequencing process to come. Promising!
youtu.be/G8ECt04qPos?...
Introducing Roche Sequencing by Expansion (SBX) Technology
YouTube video by Roche
youtu.be
February 23, 2025 at 1:25 PM
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m.genome.cshlp.org/content/earl... Matt Loose in Nottingham publishes a method for Adaptive Sampling with Oxford @nanoporetech.com sequencing.
Genome Res | Mobile
m.genome.cshlp.org
February 18, 2025 at 5:26 PM
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Incroyable.

Les sbires de Trump et Musk sont entrés de force au sein de l'agence météorologique nationale (NOAA), pour lui couper les vivres et bloquer l'information climatique.

Une atteinte gravissime aux sciences, à la démocratie, à l'avenir.

www.theguardian.com/us-news/2025...
Doge staffers enter Noaa headquarters and incite reports of cuts and threats
Members reportedly sought access to IT systems at agency that Project 2025 has called ‘harmful to US prosperity’
www.theguardian.com
February 5, 2025 at 10:03 AM
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Testing a new DNA extraction protocol on a bee sample @lipme-toulouse.bsky.social.
@nanoporetech.com assembly is impressive. Looks like most of the 16 chromosomes are single T2T contigs!
Thanks @tiboleroyinen.bsky.social and your team for providing the larvae sample!
January 21, 2025 at 9:53 AM
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"➕de 50% des chercheurs et enseignants chercheurs vont partir à la retraite d'ici 2030.
Si la France ne réinvestit pas pour rendre ces métiers attractifs, elle décrochera à l'international".
Dean Lewis.
👉 @franceinter.fr : www.radiofrance.fr/franceinter/...
Baisse annoncée du budget de la recherche et de l’enseignement supérieur : quel avenir pour la recherche scientifique ?
Le projet de loi de finances 2025, adopté hier au Sénat, prévoit un coup de rabot conséquent sur le budget de la recherche et de l’enseignement supérieur, avec 630 millions d’euros d’économies. Ces re...
www.radiofrance.fr
January 24, 2025 at 9:52 PM
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Je viens de faire mon #eXit! L’exode de X est massif. Ne perdez pas un seul de vos abonnés. Grâce à #OpenPortability j’ai inscrit 1682 nouveaux passagers pour partir vers #BlueSky & #Mastodon. Retrouvez automatiquement vos communautés le #20Janvier via app.openportability.com !
app.OpenPortability.com
January 25, 2025 at 9:42 AM
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🌟 Excited to share my latest preprint with @lachlanjmc.bsky.social on @biorxivpreprint.bsky.social: "Genome size estimation from long read overlaps”! 🚀

Check it out here: doi.org/10.1101/2024...
And find the code here: github.com/mbhall88/lrge

🧵👇
doi.org
December 3, 2024 at 1:38 AM
Reposted by PGTB
Despite being listed as an author, I had no involvement in "writing" this book. It appears to include content taken from freely available CC BY publications, including ours. To save $69, you can access our study for free in @newphyt.bsky.social:
doi.org/10.1111/nph....
#OpenAccess #Anthocyanins
January 6, 2025 at 9:52 PM
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New year, new assemblies!
I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes!
It's the successor to Trycycler, designed to be faster and less reliant on user intervention.
Check it out: github.com/rrwick/Autoc...
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Home
A tool for generating consensus long-read assemblies for bacterial genomes - rrwick/Autocycler
github.com
December 31, 2024 at 11:43 PM
Reposted by PGTB
If you've never donated to Wikipedia, now's the time. Elon Musk is attacking it because it's one of the only sources of honest, curated information that he can't control.
www.newsweek.com/elon-musk-ta...
Elon Musk takes aim at Wikipedia
The billionaire has become one of the most prominent supporters of President-elect Donald Trump.
www.newsweek.com
December 25, 2024 at 3:54 AM
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December 22, 2024 at 12:12 PM
Genomes | ATCC Genome Portal
Complete Genomes Collection
genomes.atcc.org
December 22, 2024 at 12:01 PM
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December 22, 2024 at 11:58 AM
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December 22, 2024 at 11:57 AM
Reposted by PGTB
If you’re doing DNA barcoding in a fieldwork or resource-limited context and you want to improve phylogenetic resolution at lower cost, here’s a method that allows the sequencing of 3 unlinked regions using long amplicon PCR and @nanoporetech.com MinION for ~€5 a sample.

📷 Timothy Dykes
December 19, 2024 at 12:16 PM