Lightnews — Scholar-powered news

Prasanna Satpute-Krishnan @pskcellbio.bsky.social · 9d

I can’t wait to read this!

Nature Reviews Molecular Cell Biology @natrevmcb.nature.com · 9d

New Online! Towards a unified framework for the function of endoplasmic reticulum exit sites

Towards a unified framework for the function of endoplasmic reticulum exit sites

Nature Reviews Molecular Cell Biology, Published online: 29 September 2025; doi:10.1038/s41580-025-00899-0Endoplasmic reticulum exit sites (ERES) are specialized ER subdomains that regulate the export of secreted cargo. This Roadmap explores how ERES integrate biochemical and mechanical signals to coordinate trafficking and proposes a multidisciplinary strategy to investigate their function, including in disease.

bit.ly

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Reposted by Prasanna Satpute-Krishnan

Women in Autophagy @womeninautophagy.bsky.social · 23d

📣 Deadline Extended! 📆

Abstract submissions for the WIA Symposium Webinar are now due Friday, Sept 19. Don’t miss your chance to showcase your work to the autophagy community!

👇Submit here:

forms.office.com/pages/respon...

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Reposted by Prasanna Satpute-Krishnan

The Company of Biologists @biologists.bsky.social · Aug 27

Our first extraordinary biologist featured this week is Jennifer Lippincott-Schwartz, a @jcellsci.bsky.social Editor, @focalplane.bsky.social Scientific Advisory Board member and plenary speaker at the Biologists @ 100 conference. #biologists100 #100biologists

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Reposted by Prasanna Satpute-Krishnan

Erik A. Rodriguez @erin-rod.bsky.social · Aug 22

Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday
www.nature.com/articles/nme...

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Reposted by Prasanna Satpute-Krishnan

John Cooper @johncooper314.bsky.social · Aug 20

internalmedicine.wustl.edu/obituary-stu...

Obituary: Stuart Arthur Kornfeld, MD - John T. Milliken Department of Medicine

October 4, 1936 – August 17, 2025 It is with deep sadness that I share the news that Dr. Stuart Arthur Kornfeld, Professor Emeritus, passed away on Sunday, August 17, 2025, from complications of Parki...

internalmedicine.wustl.edu

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Aug 15

Good luck! I’ve had a similar thing happened to me and in the end FedEx was not helpful. Only the sales rep was.

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Aug 15

Very frustrating! I hope that the sales rep will make this right for you.

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Reposted by Prasanna Satpute-Krishnan

Anna Leder @annaleder.bsky.social · Aug 11

Happy to share my first publication, where we present our discovery of multi-chaperone condensates that orchestrate protein folding in the endoplasmic reticulum!
www.nature.com/articles/s41...

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Aug 7

Congratulations @cohenlaboratory.bsky.social, @ibudin.bsky.social and all the 2025 ASCB award winners! This is a major achievement!

American Society for Cell Biology @ascbiology.bsky.social · Aug 4

Meet the 2025 ASCB Award Winners—trailblazing scientists honored for research, mentoring, education, and innovation. Celebrate excellence across all career stages in cell biology. Read more: www.ascb.org/society-news...

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Reposted by Prasanna Satpute-Krishnan

Marine Biological Laboratory @mblscience.bsky.social · Jul 28

We're thrilled to announce the largest private gift in our 137-year history: a $25 million unrestricted donation from MBL Whitman Scientist Mark Terasaki.

His extraordinary generosity will bolster our renowned research and education programs. 🔬

Learn more: bit.ly/452WL1m

MBL Announces Largest Ever Gift for Its Renowned Biological Education and Research Programs | Marine Biological Laboratory

Cell Biology Researcher Mark Terasaki’s $25 Million Unrestricted Gift Will Support Operations and Infrastructure Contact: Samantha Cummis [email protected]; 973.800.4119

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Jun 24

#Golgi folks, cannot miss this!

Felix Campelo @felixmendu.bsky.social · Jun 23

The #MembraneTrafficking online seminars are back this Thursday (June 26th, 5pm CEST). We'll hear from @jnuechel.bsky.social about how to find the right partner for a TANGO, and from Maohan Su about the organizational principles of the Golgi. @ishier.bsky.social @franbottanelli.bsky.social

MEMBRANE TRAFFICKING | Membrane Trafficking

felixcampelo.wixsite.com

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Reposted by Prasanna Satpute-Krishnan

Science Magazine @science.org · Jun 20

What do you see when you stare at this grid of line segments: a series of rectangles, or a series of circles?

The way you perceive this optical illusion may tie back to the visual environment that surrounds you, a recent preprint suggests. scim.ag/4kTxbmd

Culture literally changes how we see the world

Where city dwellers see rectangles, people who live in round huts see circles

scim.ag

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · May 24

Thank you so much for posting this, @xianglab.bsky.social

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · May 22

💯

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Reposted by Prasanna Satpute-Krishnan

Kara Marshall @karalmarshall.bsky.social · May 3

Gave a talk at my parents’ retirement community to describe how science is done, and what is at stake. There was a ton of interest, and anyone can do this. Get the word out about how science affects everyone. I’m happy to share slides with anyone who asks- just get in touch! youtu.be/BY_SFgi-Cig

Kara Marshall PHD-History of Science in America - Trilogy at Tehaleh 04/27/25

YouTube video by Steve Lawson

youtu.be

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Reposted by Prasanna Satpute-Krishnan

Roberto Zoncu Lab @robzonculab.bsky.social · Apr 28

tinyurl.com/mrce6bbb Fun to write this N&V together with Regina @hrshin.bsky.social, on the several cryoEM papers that build on her discovery of the fascinating LYCHOS protein and its role in cholesterol sensing and mTORC1 regulation!

Cholesterol finds its pocket in LYCHOS - Nature Structural & Molecular Biology

The lysosomal transmembrane protein LYCHOS enables activation of the master growth regulator mTORC1 kinase by cholesterol. Here we summarize recent structural findings that shed light on the LYCHOS ch...

tinyurl.com

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Reposted by Prasanna Satpute-Krishnan

Anirban Banerjee @banirbn.bsky.social · Apr 8

Interested in chemical mechanisms of membrane proteins ?We have an opening for postbac fellows. Please share and repost. Thanks !
Our research focuses on understanding the chemical and cellular mechanisms of integral membrane enzymes and transition metal transporters.
bit.ly/42jWXYD.
/n

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Apr 24

Congratulations to Emmanuel and the team!

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Reposted by Prasanna Satpute-Krishnan

Guillaume Thibault @gthibault.bsky.social · Apr 21

Visiting Cambridge/Oxford/London w/ @sim0nredfern.bsky.social to connect w/ potential applicants for Nanyang Assistant Professorship (NAP) @ NTU SG. NAP offers tenure-track position w/ up to S$2.75M start-up. Join us and register at one of our recruitment events 👇
www.ntu.edu.sg/science/rese...

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Apr 20

Happy Golgi Day, Ishier! Now I expect to celebrate yearly :)

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Apr 20

Happy Golgi Day!!
I’m celebrating in the lab!

Ishier Raote @ishier.bsky.social · Apr 16

On April 19, 1898, Camillo Golgi described what we now know as the #Golgi apparatus - a structure so pretty and unusual it took over fifty years for the scientific community to agree it wasn’t just an artefact.
April 19 is #GolgiDay! Mark your calendars to honour the best organelle.

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Apr 11

This is a well written spotlight piece by Xin Xiang @xianglab.bsky.social highlighting a new discovery by Aquino et al in McNally lab. It describes a novel mechanism by which the kinesin-1-driven inward organelle packing pushes the spindle out towards the cortex. Interesting mechanism and biology!

Xin Xiang @xianglab.bsky.social · Apr 10

Happy to share this short spotlight piece kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F... published online by @cp-trendscellbio.bsky.social
for an interesting paper about an unexpected mechanism behind Kinesin-1-mediated meiotic spindle positioning in C. elegans @cp-cellreports.bsky.social

kwnsfk27.r.eu-west-1.awstrack.me

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Mar 30

Exciting discovery by Aakriti Jain @aakritijain.bsky.social et al of the @robzonculab.bsky.social lab that LyLAP processively and rapidly proteolyses membrane-spanning hydrophobic domains of transmembrane proteins!

Aakriti Jain @aakritijain.bsky.social · Mar 27

SO excited to share that a major part of the postdoctoral work in @robzonculab.bsky.social lab is now published: “Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins” www.science.org/doi/10.1126/...

Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Breakdown of every transmembrane protein trafficked to lysosomes requires proteolysis of their hydrophobic helical transmembrane domains. Combining lysosomal proteomics with functional genomic dataset...

www.science.org

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Prasanna Satpute-Krishnan @pskcellbio.bsky.social · Mar 30

Congratulations Aakriti! It’s great to see this exciting story published!

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Reposted by Prasanna Satpute-Krishnan

Fran Bottanelli @franbottanelli.bsky.social · Mar 26

Hey #scisky has anybody made the move to FBS substitutes for their research and is happy??? I soon may need a grant just to fund lab FBS 😭

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