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ryanase.bsky.social
Ryuji Yanase
@ryanase.bsky.social
270 followers 420 following 4 posts
Research Associate at Uni of Leicester & Uni of Nottingham. Interested in protozoan parasites, parasite-vector interactions, and meiosis.
Posts Media Videos Starter Packs
Reposted by Ryuji Yanase
cellarchlab.com
Ben Engel @cellarchlab.com · 13d
Time for a thread!🧵 How different is the molecular organization of thylakoids in “higher” plants🌱? To find out, we teamed up with @profmattjohnson.bsky.social to dive into spinach chloroplasts with #CryoET ❄️🔬. Curious? ..Read on!

#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
1/🧵
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Reposted by Ryuji Yanase
elife.bsky.social
eLife @elife.bsky.social · 18d
🌱 Using ‘compelling’ methods, including #CryoET, researchers mapped spinach thylakoid membranes at single-molecule precision, revealing how photosynthetic complexes are organised and settling long-standing debates on chloroplast architecture.
buff.ly/j3TSIkn
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Reposted by Ryuji Yanase
cp-trendsparasitol.bsky.social
Trends in Parasitology @cp-trendsparasitol.bsky.social · Sep 4
Our 2025 Sep issue bit.ly/2N9R8Es reviews species sanitation & structural resilience in malaria control, animal trypanosomosis control, parasite genome organization, Leishmania attachment in sandflies, nonchemotherapeutic nematode control, tick & host microbiotas, parasitic neural manipulation &more
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Reposted by Ryuji Yanase
bspparasitology.bsky.social
British Society for Parasitology @bspparasitology.bsky.social · Sep 1
A big welcome to everyone who has joined us for the @bspparasitology.bsky.social trypanosomiasis and leishmaniasis meeting this week in the beautiful city of Ceske Budějovice!
Title slide being projected on a screen for the BSP trypanosomiasis and leishmaniasis seminar View of Ceske Budějovice from above. Beautiful city with coloured houses on a clear sunny day
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Reposted by Ryuji Yanase
tbharat-lab.bsky.social
Tanmay Bharat @tbharat-lab.bsky.social · Aug 31
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
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Reposted by Ryuji Yanase
eelcotromer.bsky.social
Eelco Tromer @eelcotromer.bsky.social · Aug 31
New work on ARK1 (AURKB?) in Plasmodium (malaria parasite) with @ritatewari.bsky.social and Pushkar Sharma. CPC in Plasmodium is (ofcourse..) different compared to conventional models: two INCENPs, no borealin/survivin - mainly at spindle microtubules/MTOCs. Special thanks to @ryanase.bsky.social!
ryanase.bsky.social
Ryuji Yanase @ryanase.bsky.social · Aug 28
Pleased to share our new preprint: "Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex". Many thanks to our collaborators.
@ritatewari.bsky.social @eelcotromer.bsky.social @davidguttery.bsky.social

www.biorxiv.org/content/10.1...
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ryanase.bsky.social
Ryuji Yanase @ryanase.bsky.social · Aug 28
Pleased to share our new preprint: "Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex". Many thanks to our collaborators.
@ritatewari.bsky.social @eelcotromer.bsky.social @davidguttery.bsky.social

www.biorxiv.org/content/10.1...
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Reposted by Ryuji Yanase
kristina-prokina.bsky.social
Kristina Prokina @kristina-prokina.bsky.social · Aug 26
New paper is out! We have studied the cute tiny Discocelia plataet sp. n. to obtain the first molecular data of the order Discocelida and clarify its cell structure. All this for a better understanding of the evolution of Cercozoa.

onlinelibrary.wiley.com/doi/epdf/10....
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Reposted by Ryuji Yanase
juanquintana.bsky.social
Quintana Lab @juanquintana.bsky.social · Aug 16
Such a great story! A pathogen within a pathogen 🤯. Made me think of all Totiviridea family that infect protozoan parasites including Trichomonas vaginalis and Giardia lamblia. Always wondered if Tryps have these too and whether the pathology is partly due to a hidden bug.
shlezingerlab.bsky.social
Neta Shlezinger @shlezingerlab.bsky.social · Aug 14
🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️
Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology
A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.
doi.org
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Reposted by Ryuji Yanase
fariatrypslab.bsky.social
Faria Tryps Lab @fariatrypslab.bsky.social · Aug 11
How do parasites strategically organise their genomes to influence gene expression? If you’re curious, check our latest review in @cp-trendsparasitol.bsky.social !

@biologyatyork.bsky.social @ybri-uoy.bsky.social @pasteur.fr

www.sciencedirect.com/science/arti...
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Reposted by Ryuji Yanase
bungoakiyoshi.bsky.social
Bungo Akiyoshi @bungoakiyoshi.bsky.social · Aug 6
My attempt to become a professor was unsuccessful again but the diplonema tagging paper is now published in Open Biology. royalsocietypublishing.org/doi/10.1098/...
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Reposted by Ryuji Yanase
micromotility.bsky.social
Kirsty Wan @micromotility.bsky.social · Aug 6
We have a postdoc opening for a protistologist with biophysics inclinations to join our @hfspo.bsky.social project! (focus will be on characterising the morphology, ultrastructure and behaviour of excavates) #protistsonsky

Apply by Sept 17th (RTs appreciated!)
jobs.exeter.ac.uk/hrpr_webrecr...
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Reposted by Ryuji Yanase
ghostpathogen.bsky.social
bishara marzook @ghostpathogen.bsky.social · Jul 24
Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now! www.cell.com/cell/fulltex...
The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment
An arrayed microscopy-based CRISPR screen revealed host genes affecting multiple infection phenotypes of the intracellular parasite Cryptosporidium. Hits in the host cholesterol biosynthesis pathway a...
www.cell.com
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Reposted by Ryuji Yanase
zlatogursky.bsky.social
Vasily Zlatogursky @zlatogursky.bsky.social · Jul 24
Promethea = PROvora + MEteora + HEmimastigophora. The new supergroup, unifying previously “orphan” lineages with gene-rich mitogenomes. Position of #telonemids is still uncertain. #protistsonsky tinyurl.com/yk9xkt49
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Reposted by Ryuji Yanase
cp-trendsparasitol.bsky.social
Trends in Parasitology @cp-trendsparasitol.bsky.social · Jul 23
Drs Petr Volf, Katerina Pruzinova @ryanase.bsky.social‬ & Jack Sunter review #midgut & #stomodeal #valve #attachment of #Leishmania in #sandflies. #Kinetoplastid #Haptomonad #Promastigote #SecretoryGel @sciencecharles.bsky.social‬ @charlesuni.cuni.cz‬

authors.elsevier.com/a/1lTsW5Eb1x...
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Reposted by Ryuji Yanase
ellenberglab.bsky.social
Ellenberg Lab @ellenberglab.bsky.social · Jul 21
Our new non-denaturing nanoscale 3D DNA tracing technology provides single-cell (and sister-chromatid specific!) readout of chromatin structure with 10kb genomic resolution - Check it out!

www.nature.com/articles/s41...

Congratulations to Kai and Oyvind!!
Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ - Nature Communications
A nanoscale 3D DNA tracing workflow visualizes Cohesin-dependent loops in single, structurally well-preserved cells. Computer simulations based on the tracing data give further insight into how Cohesi...
www.nature.com
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Reposted by Ryuji Yanase
maxhaase.bsky.social
Max Haase @maxhaase.bsky.social · Apr 25
It’s out! The evolutionary origins of yeast point centromeres uncovered!

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.biorxiv.org/content/10.1...
Ancient co-option of LTR retrotransposons as yeast centromeres
The evolutionary origins of the genetic point centromere in the brewer's yeast Saccharomyces cerevisiae, a member of the order Saccharomycetales, are still unknown. Competing hypotheses suggest that t...
www.biorxiv.org
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Reposted by Ryuji Yanase
eelcotromer.bsky.social
Eelco Tromer @eelcotromer.bsky.social · Jun 23
Happy to see our work published and glad to have contributed together with @maxraas.bsky.social ! Looking forward to all the projects that will come out of this work!
lauraeme.bsky.social
Laura Eme @lauraeme.bsky.social · Jun 22
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.

🔗: doi.org/10.1016/j.ce...

#Genomics #Evolution #CellBiology #LECA
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Reposted by Ryuji Yanase
lauraeme.bsky.social
Laura Eme @lauraeme.bsky.social · Jun 22
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.

🔗: doi.org/10.1016/j.ce...

#Genomics #Evolution #CellBiology #LECA
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Reposted by Ryuji Yanase
biorxiv-microbiol.bsky.social
bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Jun 17
Genome-wide CRISPR base-editing screening defines drug response networks in Leishmania https://www.biorxiv.org/content/10.1101/2025.06.16.659792v1
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Reposted by Ryuji Yanase
enniscath.bsky.social
🇨🇦Cath Ennis🇨🇦 @enniscath.bsky.social · Jun 16
This is wild! Stay weird, evolution | Microbe with bizarrely tiny genome may be evolving into a virus | Science | AAAS www.science.org/content/arti...
Microbe with bizarrely tiny genome may be evolving into a virus
With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses
www.science.org
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Reposted by Ryuji Yanase
parasitematt.bsky.social
Matt Higgins @parasitematt.bsky.social · Jun 13
Our latest story describes the amazing evolutionary battle between malaria parasite and human. The parasite evolved RIFINs to bind inhibitory KIR receptors and suppress immune cell function while humans have activating KIR receptors to bind these RIFINs to kill parasites!
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Reposted by Ryuji Yanase
francoismayer.bsky.social
François Mayer @francoismayer.bsky.social · Jun 13
Awesome malaria study out now in Nature Microbiology:

An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission

By Franziska Hentzschel, Matthias Marti, Freddy Frischknecht & colleagues!

@freddyfrischknecht.bsky.social

www.nature.com/articles/s41...
An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission - Nature Microbiology
A unique Arp2/3 complex in malaria parasites enables DNA segregation during the rapid formation of male gametes by safeguarding the attachment of chromosomes to the mitotic spindle.
www.nature.com
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Reposted by Ryuji Yanase
strassert.bsky.social
Jürgen Strassert @strassert.bsky.social · Jun 13
Happy to have contributed to this great article: #Protist genomics: key to understanding eukaryotic evolution. Congrats Alexandra Schoenle et al. #ProtistsOnSky
authors.elsevier.com/sd/article/S...
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Reposted by Ryuji Yanase
bastinlab.bsky.social
Philippe Bastin's Lab @bastinlab.bsky.social · Jun 12
Daniel's paper is now published in @jcellsci.bsky.social, great experience with @reviewcommons.org 😀

Want to know everything tubulin assembly in trypanosome flagella and other microtubules? Here is the link:

journals.biologists.com/jcs/article/...
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