Megan Bergkessel
@slowgoing.bsky.social
Microbiologist at the University of Dundee studying bacterial life "in the slow lane", under stressful conditions that limit growth.
Reposted by Megan Bergkessel
Regulatory Rewiring Drives Intraspecies Competition in Bacillus subtilis
bioRxiv from @bacteriacities.bsky.social
#competition #rapP #comP
www.biorxiv.org/content/10.1...
bioRxiv from @bacteriacities.bsky.social
#competition #rapP #comP
www.biorxiv.org/content/10.1...
Regulatory Rewiring Drives Intraspecies Competition in Bacillus subtilis
Intraspecies interactions shapes microbial community structure and evolution, yet the mechanisms determining competitive outcomes among closely related strains remain unclear. The soil bacterium Bacil...
www.biorxiv.org
December 1, 2025 at 1:33 PM
Regulatory Rewiring Drives Intraspecies Competition in Bacillus subtilis
bioRxiv from @bacteriacities.bsky.social
#competition #rapP #comP
www.biorxiv.org/content/10.1...
bioRxiv from @bacteriacities.bsky.social
#competition #rapP #comP
www.biorxiv.org/content/10.1...
Reposted by Megan Bergkessel
Identification of Previously Unknown DNA-Binding Proteins Using DNA Affinity/Pull-Down Methods Followed by Mass Spectrometry
Jutras, Babb, Jusufovic, Krusenstjerna, Saylor, Verma, and Stevenson
Current Protocols 2025, 5:e70264
doi: 10.1002/cpz1.70264
#MicroSky
Jutras, Babb, Jusufovic, Krusenstjerna, Saylor, Verma, and Stevenson
Current Protocols 2025, 5:e70264
doi: 10.1002/cpz1.70264
#MicroSky
November 26, 2025 at 4:00 PM
Identification of Previously Unknown DNA-Binding Proteins Using DNA Affinity/Pull-Down Methods Followed by Mass Spectrometry
Jutras, Babb, Jusufovic, Krusenstjerna, Saylor, Verma, and Stevenson
Current Protocols 2025, 5:e70264
doi: 10.1002/cpz1.70264
#MicroSky
Jutras, Babb, Jusufovic, Krusenstjerna, Saylor, Verma, and Stevenson
Current Protocols 2025, 5:e70264
doi: 10.1002/cpz1.70264
#MicroSky
Reposted by Megan Bergkessel
🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages.
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
November 20, 2025 at 8:40 PM
🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages.
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.
A thread 1/8
Reposted by Megan Bergkessel
An Rhs effector uses distinct target cell functions to intoxicate bacterial and fungal competitors https://www.biorxiv.org/content/10.1101/2025.10.28.685041v1
October 29, 2025 at 2:18 AM
An Rhs effector uses distinct target cell functions to intoxicate bacterial and fungal competitors https://www.biorxiv.org/content/10.1101/2025.10.28.685041v1
Reposted by Megan Bergkessel
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
October 3, 2025 at 4:06 PM
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
New preprint from the lab! @findunmun1.bsky.social @chemsley.bsky.social We looked at new protein synthesis and genetic fitness during starvation in P. aeruginosa. Resources are dynamically redistributed to support ongoing activity, even over days of total starvation: www.biorxiv.org/content/10.1...
Analyses of protein expression and genetic fitness determinants reveal dynamic pathways active in starved Pseudomonas aeruginosa
Heterotrophic bacteria rapidly deplete essential macronutrients during growth and must navigate subsequent periods of growth arrest imposed by starvation. Nutrient limitations can be dynamic in nature...
www.biorxiv.org
September 29, 2025 at 7:23 PM
New preprint from the lab! @findunmun1.bsky.social @chemsley.bsky.social We looked at new protein synthesis and genetic fitness during starvation in P. aeruginosa. Resources are dynamically redistributed to support ongoing activity, even over days of total starvation: www.biorxiv.org/content/10.1...
Reposted by Megan Bergkessel
yes, the MMBs studied by george schaible and roland hatzenpichler are fascinating 𝗼𝗯𝗹𝗶𝗴𝗮𝘁𝗲 𝗺𝘂𝗹𝘁𝗶𝗰𝗲𝗹𝗹𝘂𝗹𝗮𝗿 bacteria 🤩
STC had mentioned them first in 2007 > schaechter.asmblog.org/schaechter/2...
and recently in > schaechter.asmblog.org/schaechter/2...
#MicroSky
STC had mentioned them first in 2007 > schaechter.asmblog.org/schaechter/2...
and recently in > schaechter.asmblog.org/schaechter/2...
#MicroSky
April 9, 2025 at 12:04 PM
yes, the MMBs studied by george schaible and roland hatzenpichler are fascinating 𝗼𝗯𝗹𝗶𝗴𝗮𝘁𝗲 𝗺𝘂𝗹𝘁𝗶𝗰𝗲𝗹𝗹𝘂𝗹𝗮𝗿 bacteria 🤩
STC had mentioned them first in 2007 > schaechter.asmblog.org/schaechter/2...
and recently in > schaechter.asmblog.org/schaechter/2...
#MicroSky
STC had mentioned them first in 2007 > schaechter.asmblog.org/schaechter/2...
and recently in > schaechter.asmblog.org/schaechter/2...
#MicroSky
Reposted by Megan Bergkessel
In @molecularmicro.bsky.social: two special issues on Prokaryotic Chromosome Organization. Many excellent contributions, including a vision article: 'Future directions of the Prokaryotic Chromosome Field', outcome of BioPhyChrom 2023 @biophychrom.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
Future Directions of the Prokaryotic Chromosome Field
In September 2023, the Biology and Physics of Prokaryotic Chromosomes meeting ran at the Lorentz Center in Leiden, The Netherlands. As part of the workshop, those in attendance developed a series of ....
onlinelibrary.wiley.com
February 20, 2025 at 8:14 PM
In @molecularmicro.bsky.social: two special issues on Prokaryotic Chromosome Organization. Many excellent contributions, including a vision article: 'Future directions of the Prokaryotic Chromosome Field', outcome of BioPhyChrom 2023 @biophychrom.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Megan Bergkessel
Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure onlinelibrary.wiley.com/doi/10.1111/... #jcampubs
Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure
Polyphosphate condensates and their contributions to nucleoid structure. Polyphosphate condensates form in the ribosome-depleted nucleoid region of bacterial cells, particularly under stress (in this...
onlinelibrary.wiley.com
February 19, 2025 at 2:17 PM
Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure onlinelibrary.wiley.com/doi/10.1111/... #jcampubs
Reposted by Megan Bergkessel
January 23, 2025 at 10:56 PM
Congrats to Findlay and many thanks to examiners Dan Neill and Martin Welch for their work on a successful viva today! Findlay has worked so hard and accomplished so much while blazing the trail as the first PhD student in the lab :)
January 16, 2025 at 5:22 PM
Congrats to Findlay and many thanks to examiners Dan Neill and Martin Welch for their work on a successful viva today! Findlay has worked so hard and accomplished so much while blazing the trail as the first PhD student in the lab :)
Reposted by Megan Bergkessel
Together with @frimanscience.bsky.social and our Chinese colleagues, we have worked out how to predict
(i) siderophore molecular structures
www.biorxiv.org/content/10.1...
and
(ii) siderophore interaction networks in communities
www.biorxiv.org/content/10.1...
from sequence data!
(i) siderophore molecular structures
www.biorxiv.org/content/10.1...
and
(ii) siderophore interaction networks in communities
www.biorxiv.org/content/10.1...
from sequence data!
November 14, 2024 at 1:37 PM
Together with @frimanscience.bsky.social and our Chinese colleagues, we have worked out how to predict
(i) siderophore molecular structures
www.biorxiv.org/content/10.1...
and
(ii) siderophore interaction networks in communities
www.biorxiv.org/content/10.1...
from sequence data!
(i) siderophore molecular structures
www.biorxiv.org/content/10.1...
and
(ii) siderophore interaction networks in communities
www.biorxiv.org/content/10.1...
from sequence data!