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Reposted by Joanna Smeeton

NY-CURES @nycures.bsky.social · 6d

The BIGGEST impact you can have with 1 minute today ⏱️

Add your name to show NY is ready for a statewide biomedical institute.

CA’s CIRM & TX’s CPRIT proved it works—billions returned, jobs created, cures accelerated. Let’s do even better for New York.

✍️ www.nycures.org/

New York Cures – NY-CURESNew York Cures Website

NY-CURES is working to advance bold, state-backed investment in biomedical research—on the scale of successful initiatives in California and Texas—to grow New York’s leadership in science, innovation, and health.

www.nycures.org

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Joanna Smeeton @smeetonlab.bsky.social · 9d

📣🧪 Read our latest #research on joint regeneration in #zebrafish, published today in @natcomms.nature.com www.nature.com/articles/s41... @columbiauniversity.bsky.social

Dynamic cell fate plasticity and tissue reintegration drive functional adult synovial joint regeneration after complete resection - Nature Communications

Joint injury and disease are leading causes of disability, with mammalian joints exhibiting poor regenerative capacity. Here the authors showed that after loss of a whole joint, adult zebrafish regenerate de novo articular cartilage, ligament, and synovium into a complex joint organ.

www.nature.com

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Joanna Smeeton @smeetonlab.bsky.social · 14d

🍾🧪The end of an era! Today we said so long to Dr. Troy Anderson. Troy was the very first person to join me in the Smeeton lab. He just defended his PhD and is off to start his postdoc next month. We will miss you Troy!! #proudPI @troy-anderson.bsky.social #zebrafish

A photo of Joanna Smeeton and Troy Anderson. Joanna is pointing to the PhD celebration champagne cork from Troy's defense that he is holding

Troy smiling and holding a box after packing up his desk.

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Orthopaedic Research Society @orssociety.bsky.social · Aug 28

Register now for an ORS Tendon Section #WebinarWednesday on Sept 24, 12 PM CST, A Tendon-cy to Heal: Regenerating Tendons & Ligaments in Zebrafish. Hear from Thomas Schilling, Jenna Galloway & Joanna Smeeton on the latest #tendon & ligament regeneration. 🔗 ors.memberclicks.net/ten092425web#/

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Joanna Smeeton @smeetonlab.bsky.social · Jun 30

Thank you Kevin for all that you have done to get our community schooling together online. I really appreciate all your hard work and engaging posts!! See you over on the Slack channel to keep the conversations going.

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Zebrafish Rock! @zebrafishrock.bsky.social · Jun 6

Due to their aquatic environment, #zebrafish are perfect for small molecule drug screens. Many drugs have been repurposed for novel treatments such as COX inhibitors in leukemia & glucocorticoids in long QT syndrome. For more, read this Nature review ($): doi.org/10.1038/nrd4... #ZebrafishFunFacts 🧪

Figure taken from MacRae & Peterson (2015): How suitable are zebrafish for discovering human drugs? Although zebrafish enable in vivo studies on a large scale, questions remain about how relevant the findings are for drug discovery. Recent studies have begun to elucidate the degree of conservation between humans and zebrafish, which share 82% of disease-associated targets and a large number of drug metabolism pathways (as illustrated by the mass spectrometry of metabolic by-products). Zebrafish physiology is often well conserved (sometimes more so than rodent physiology); for example, cardiac electrophysiology (illustrative electrocardiogram (ECG) tracings from each organism are shown). Several compounds discovered in zebrafish screens have been shown to exhibit similar effects in rodent models and humans, including eight out of ten compounds tested by our groups. m/z, mass to charge ratio.

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Zebrafish Rock! @zebrafishrock.bsky.social · Jun 1

Revascularization of coronary endothelial cells during zebrafish heart regeneration. Credit to @harrisonlab.bsky.social. #ZebrafishZunday 🧪

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Shawn Burgess @burgesslab.bsky.social · May 15

Some exciting news! NCBI has finished the annotation pipeline for our new #zebrafish reference sequence GRCz12tu:
www.ncbi.nlm.nih.gov/refseq/annot...

This is a big step up in data depth and quality and should be super helpful going forward.

Danio rerio Annotation ReportTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube

www.ncbi.nlm.nih.gov

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International Zebrafish Society @izfs.bsky.social · Apr 17

We are excited to announce our next issue of #NewsSplash has been published! To keep up with all the latest #zebrafish news, be sure to check it out here: www.izfs.org/newssplash/n...

News Splash Issue 19 Spring 2025 | IZFS - International Zebrafish Society

www.izfs.org

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Joanna Smeeton @smeetonlab.bsky.social · Apr 4

Congratulations Olena!!

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Joanna Smeeton @smeetonlab.bsky.social · Apr 2

Congratulations Peter!!

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Ele Willoughby @minouette.bsky.social · Mar 20

Happy birthday to Canadian medical researcher & #biochemist Maud Menten (1879-1960). 🧪🐡👩🏼‍🔬 #histscj Not only was she an author of Michaelis-Menten equation for enzyme kinetics, she invented the azo-dye coupling for alkaline phosphatase, 1st example of enzyme histochemistry, still used in imaging of 🧵

Linocut portrait of biochemist and medical researcher Maud Menten (1879-1960) with the Michalis-Menten equation in blue and a histology image in pinks and purples in the background.

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Joanna Smeeton @smeetonlab.bsky.social · Mar 6

Heading back to NYC full of fresh ideas and new questions to explore after a wonderful visit with the fantastic faculty and trainees @cuanschutz.bsky.social Thanks again for the invitation to share our work on craniofacial joint regeneration!

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International Zebrafish Society @izfs.bsky.social · Feb 10

Abstract submissions for the 19th IZFC are now open! Registration to the conference is required to submit an abstract. Register and submit here today! www.izfs.org/education/19...

Abstracts | IZFS

www.izfs.org

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Science Magazine @science.org · Feb 10

Breaking news: 22 states are suing to block NIH’s cutting of indirect costs.

See our updated story on the Friday night news and its aftermath. scim.ag/4hTJQ6v

NIH slashes overhead payments for research, sparking outrage and lawsuit

Move to cut indirect cost rate to 15% could cost universities billions of dollars

scim.ag

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Joanna Smeeton @smeetonlab.bsky.social · Feb 8

These opening sessions talks were exactly what I needed after the week we have had.

Joanna Smeeton @smeetonlab.bsky.social · Feb 8

"We need eachother more than ever before" #ORS2025

ORS President at a podium in front of a screen showing the word Community

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Carl T. Bergstrom @carlbergstrom.com · Feb 8

1. Today the NIH director issued a new directive slashing overhead rates to 15%.

I want to provide some context on what that means and why it matters.

grants.nih.gov/grants/guide...

NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD

grants.nih.gov

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Zebrafish Information Network (ZFIN) @zfinmod.bsky.social · Feb 3

ZFIN is now on Bluesky!

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Katie Mack @astrokatie.com · Jan 28

I think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service.

“Pausing” grants means people don’t eat.

White House pauses all federal grants, sparking confusion

The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.

www.washingtonpost.com

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Crump Lab @crumplab.bsky.social · Jan 22

Nice article in Scientific American about our work on outer ear evolution and a complimentary study from the lab of Maksim Plikus on role of unique lipids in mammalian ear cartilage. www.scientificamerican.com/article/our-...

Our Ears Share a Common Ancestry with Fish Gills

The genes that build the cartilage of fish gills were repurposed to build the cartilage in mammals’ outer ears

www.scientificamerican.com

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Development @dev-journal.bsky.social · Jan 22

Sox10 is required for systemic initiation of bone mineralization

Read this #OpenAccess Research Article by Stefani Gjorcheska, Lindsey Barske & co. @cincyresearch.bsky.social :
https://journals.biologists.com/dev/article/152/2/dev204357/365396/Sox10-is-required-for-systemic-initiation-of-bone

Figure 1 (A) Example images illustrating a major delay in initiation of bone mineralization in sox10 mutants between 3 and 7 dpf revealed by Alizarin Red staining. Some mineralization is present by 5 dpf but never achieves control levels before lethality at 8 dpf.

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Megan Killian @megankillian.bsky.social · Jan 14

Are you a trainee in the @orssociety.bsky.social Tendon Section, and are the presenting author on an abstract at this year's meeting? If you are going to be at the annual meeting, sign up to compete in the 3-minute-thesis competition! $$ prizes will be awarded! forms.gle/WneTNbVpuECP...

2025 ORS Tendon Section: 3 Minute Thesis competition

We invite you to apply to give a short presentation (think “elevator pitch” or short TED talk) to share your thesis research/concept to your peers! This contest is designed for you to communicate your...

forms.gle

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Science Magazine @science.org · Jan 15

Slow-motion videos reveal tree frogs making some of the most dramatic landings in nature.

Learn more: scim.ag/4gTAurn

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Gettin' Fishy With It Podcast @gettinfishypod.bsky.social · Jan 10

Season 3 is here! Hear about our thoughts on season 2, and what we look forward to in season 3! From live streams to live panels at massive gaming conventions, 2024 was so incredible! 2025 is already shaping up to be an amazing year for the podcast, so be sure to tune in!

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