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souvik-uthealth.bsky.social
Souvik Bhattacharyya
@souvik-uthealth.bsky.social
2.1K followers 1K following 250 posts
Assistant Professor @University of Texas Health Science Center at Houston; #NewPI Bacterial behavior, Antibiotics, Bacterial Memory, Necrosignal; GGMU, Chess, Photography; ⚽ ♟️ 📷 he/him www.souvikbhattacharyyalab.org
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souvik-uthealth.bsky.social
Souvik Bhattacharyya @souvik-uthealth.bsky.social · Aug 15
We are hiring, spread the word!
Tenure-Track Assistant Professor positions — join our fantastic Department of Microbiology and Molecular Genetics at UTHealth McGovern Med, in the beautiful city of Houston! Applicants from all areas of microbiology are welcome. #microsky

careers.uth.tmc.edu/HRzUmB5
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Reposted by Souvik Bhattacharyya
laurahelmuth.bsky.social
Laura Helmuth @laurahelmuth.bsky.social · 7h
Six of the nine Nobel Prize winners this year work in the U.S.
Three of the six were born outside the U.S., which is the pattern most years. No country has benefited more from welcoming immigrants from around the world.
www.nobelprize.org
The official website of the Nobel Prize - NobelPrize.org
The Nobel Prize rewards science, humanism and peace efforts. This is one of the central concepts in the will of Alfred Nobel, and it also permeates the outreach activities that have been developed for...
www.nobelprize.org
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Reposted by Souvik Bhattacharyya
phillewis.bsky.social
Phil Lewis @phillewis.bsky.social · 7d
Jane Goodall, ethologist and conservationist, has died. She was 91
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Reposted by Souvik Bhattacharyya
peiferlabunc.bsky.social
Mark Peifer (He, him) @peiferlabunc.bsky.social · 11d
Here's my comment--join me. This would effectively remove foreign PhD students and postdocs from our labs. please share
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Reposted by Souvik Bhattacharyya
campy-bara.bsky.social
Sarah Svensson @campy-bara.bsky.social · 12d
Dual transposon sequencing profiles the genetic interaction landscape in bacteria | Science www.science.org/doi/10.1126/...
Dual transposon sequencing profiles the genetic interaction landscape in bacteria
Gene redundancy complicates systematic characterization of gene function as single-gene deletions may not produce discernible phenotypes. We report dual transposon sequencing (dual Tn-seq), a platform...
www.science.org
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Reposted by Souvik Bhattacharyya
drugmonkey.bsky.social
Drug Monkey @drugmonkey.bsky.social · 12d
This may be the most important paper ever published about NIH funded research.

www.science.org/doi/10.1126/...
What if NIH had been 40% smaller?
Replaying history with less NIH funding shows widespread impacts on drug-linked research
www.science.org
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Reposted by Souvik Bhattacharyya
zaminiqbal.bsky.social
Zamin Iqbal @zaminiqbal.bsky.social · 12d
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n
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hannahmrowland.bsky.social
Dr Hannah M. Rowland @hannahmrowland.bsky.social · 13d
🌍🦋 Across 6 continents, 21 sites & 15,000 paper moths, we joined a worldwide experiment led by @wlallen.bsky.social & Iliana Medina, showing how ecological context shapes the evolution of animal colouration.

Proud to be part of this global team effort: doi.org/10.1126/scie...
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Reposted by Souvik Bhattacharyya
adamrutherford.bsky.social
Adam Rutherford @adamrutherford.bsky.social · 14d
Phenomenal. In my 10 year update of A Brief History, I make the point that in the first edition, not one disease had been successfully treated using gene therapy. Today that number is at least 7.
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Reposted by Souvik Bhattacharyya
patchthompson.bsky.social
Patch Thompson @patchthompson.bsky.social · 14d
Anyway, here is some actually incredible news

www.bbc.co.uk/news/article...
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
www.bbc.co.uk
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souvik-uthealth.bsky.social
Souvik Bhattacharyya @souvik-uthealth.bsky.social · 16d
Sure, done!
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juliusbrennecke.bsky.social
Julius Brennecke @juliusbrennecke.bsky.social · 21d
PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity.

But how does piRNA-guided target interaction translate into silencing?

PhD student Júlia Portell Montserrat has an intriguing answer

www.cell.com/molecular-ce...
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Reposted by Souvik Bhattacharyya
theonion.com
The Onion @theonion.com · 22d
NIH Director’s Pulsing Neck Tumor Announces Cancer Research Cuts
NIH Director’s Pulsing Neck Tumor Announces Cancer Research Cuts
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drmikewiser.bsky.social
Mike Wiser @drmikewiser.bsky.social · 23d
This is the graph we show whenever someone talks about how back in the old days there weren't (people who are not whoever the person speaking thinks are the default).

Mostly we do this to underscore that a rise in apparent frequency isn't always a rise in real frequency.
A graph of the US population that is left-handed, by birth year. It drops from about 5% to a low of a little more than 3% from ~1890 to ~1910. It then rises steadily to about 12% around 1950, and stays at 12% out to 2000.
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jeremymberg.bsky.social
Jeremy Berg @jeremymberg.bsky.social · 24d
My quote of the day

A new breed of Republicans has taken over the GOP. It is a new breed which is seeking to sell to Americans a doctrine which is as old as mankind - the doctrine of racial division, the doctrine of racial prejudice, the doctrine of white supremacy.

Jackie Robinson (1963)
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abaumler.bsky.social
Andreas Bäumler @abaumler.bsky.social · 25d
Hydrogen sulfide production distinguishes Salmonella from close relatives, but its biological significance remains obscure. This study uncovers the secret: Salmonella uses hydrogen sulfide production as a weapon to outcompete E. coli and gain a foothold in the gut.
www.pnas.org/doi/10.1073/...
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redrockcity.bsky.social
Petra Levin @redrockcity.bsky.social · 26d
The last publication (he says!) from Rich Losick, my PhD advisor.

Historical in nature it focuses on a seminal paper in molecular biology, the study revealing the genetic code to be triplet in nature. Come for the science, appreciate the clear prose!

www.sciencedirect.com/science/arti...
Revisiting a Breathtaking Publication in the History of Molecular Biology
www.sciencedirect.com
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Reposted by Souvik Bhattacharyya
eswaralab.bsky.social
Prahathees Eswara @eswaralab.bsky.social · 26d
We are hiring! Please share the news.

Tenure Track Assistant Professor in Bacterial Pathogenesis

See link below for details.

We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴

Job Ad: tinyurl.com/USF-Microbio...
Assistant Professor - Molecular Biosciences
Department Name / Number: Molecular Biosciences / 0-1210-000 College: College of Arts and Sciences Hiring Salary: Negotiable Appointment Start Date: August 7, 2026 The Department of Molecular Bioscien...
tinyurl.com
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redrockcity.bsky.social
Petra Levin @redrockcity.bsky.social · 26d
So great to see Lucy Shapiro — a scientific hero of mine both for her pioneering work and for her incredible communication skills —honored today www.nytimes.com/2025/09/11/h...
Major Medical Prizes Given to Cell Biology and Cystic Fibrosis Pioneers
www.nytimes.com
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Reposted by Souvik Bhattacharyya
zaminiqbal.bsky.social
Zamin Iqbal @zaminiqbal.bsky.social · 28d
Sometimes you meet absolutely incredible bioinfo-magicians.
It was a huge privilege when @shenwei356.bsky.social
joined our group for a year on an @embl.org sabbatical.
While here, he developed a new way of aligning to
millions of bacteria, called LexicMap 1/n
www.nature.com/articles/s41...
Efficient sequence alignment against millions of prokaryotic genomes with LexicMap - Nature Biotechnology
LexicMap uses a fixed set of probes to efficiently query gene sequences for fast and low-memory alignment.
www.nature.com
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Reposted by Souvik Bhattacharyya
relenski.bsky.social
Richard Lenski @relenski.bsky.social · 27d
With Jeff Barrick's return to #MSU, the #LTEE was restarted today after a short pause (frozen) for the move.

Today was daily transfer 12,301. With ~6.6 generations per day, they are now at ~82,007 generations.

100,000 generations is fast approaching! Are you ready, #Spartans?

@msumgi.bsky.social
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Reposted by Souvik Bhattacharyya
geiselbiofilm.bsky.social
George O'Toole (he/him/his) @geiselbiofilm.bsky.social · Sep 8
New in JB: Kuchma, Geiger, O'Toole et al. use genetic to probe flagellar-mediated surface sensing by P. aeruginosa. (always fun to advertise my own JB papers!)
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
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tiffzarrella.bsky.social
Tiffany Zarrella @tiffzarrella.bsky.social · Sep 6
Pseudomonas aeruginosa senses exopolysaccharide trails using type IV pili and adhesins during biofilm formation by O'Toole, Parsek, & Wong groups www.nature.com/articles/s41...
Pseudomonas aeruginosa senses exopolysaccharide trails using type IV pili and adhesins during biofilm formation - Nature Microbiology
Opposing forces generated by exopolysaccharide trail binding versus type IV pilus retraction generate a high cyclic diGMP–high cyclic AMP state in Pseudomonas aeruginosa that promotes social motility.
www.nature.com
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Reposted by Souvik Bhattacharyya
kranzuschlab.bsky.social
Kranzusch Lab @kranzuschlab.bsky.social · Sep 5
How can we understand the earliest events in evolution of eukaryotic immunity? @yao-li.bsky.social reports incredible molecular fossils of complete bacterial-like operons in eukaryotes that illuminate how animal immunity was first acquired from anti-phage defense

www.biorxiv.org/content/10.1...
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Reposted by Souvik Bhattacharyya
bacteriophile.bsky.social
Animalcules @bacteriophile.bsky.social · Sep 4
www.science.org/doi/10.1126/...

#MicroSky
BioFuse: A programmable timer switch of gene expression
BioFuse offers a flexible approach to precisely timing gene expression and metabolic activities.
www.science.org
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