Amir, PharmD
@theamirimani.bsky.social
I talk about drugs, diseases, drugs, misinformation, and drugs. Opinions mine and not particularly good.
Pinned
Amir, PharmD
@theamirimani.bsky.social
· Nov 18
Reposted by Amir, PharmD
Reposted by Amir, PharmD
We've seen some remarkable outcomes in people with advanced, refractory cancers, including pancreatic, melanoma, and renal, with personalized neoantigen mRNA vaccines.
But this work is now endangered.
www.scientificamerican.com/article/pers...
But this work is now endangered.
www.scientificamerican.com/article/pers...
November 18, 2025 at 7:16 PM
We've seen some remarkable outcomes in people with advanced, refractory cancers, including pancreatic, melanoma, and renal, with personalized neoantigen mRNA vaccines.
But this work is now endangered.
www.scientificamerican.com/article/pers...
But this work is now endangered.
www.scientificamerican.com/article/pers...
Reposted by Amir, PharmD
He had a whatnow?
November 13, 2025 at 6:50 PM
He had a whatnow?
Reposted by Amir, PharmD
Ottawa! Next week! 👇
This is a critical time. A knowledge crisis. How did we get here & what can we do?
How to Escape the Fake: Making Good Policy in the Age of Misinformation : irpp.org/irpp-event/f... via @irpp.org @cmadocs.bsky.social
Hope to see there!
This is a critical time. A knowledge crisis. How did we get here & what can we do?
How to Escape the Fake: Making Good Policy in the Age of Misinformation : irpp.org/irpp-event/f... via @irpp.org @cmadocs.bsky.social
Hope to see there!
How to Escape the Fake: Making Good Policy in the Age of Misinformation - IRPP
Join us for an evening of dialogue and networking with Canada’s dynamic public policy community. This year’s IRPP fall lecture will feature Canadian author and scholar Timothy Caulfield, one of Nort...
irpp.org
November 12, 2025 at 3:24 PM
Ottawa! Next week! 👇
This is a critical time. A knowledge crisis. How did we get here & what can we do?
How to Escape the Fake: Making Good Policy in the Age of Misinformation : irpp.org/irpp-event/f... via @irpp.org @cmadocs.bsky.social
Hope to see there!
This is a critical time. A knowledge crisis. How did we get here & what can we do?
How to Escape the Fake: Making Good Policy in the Age of Misinformation : irpp.org/irpp-event/f... via @irpp.org @cmadocs.bsky.social
Hope to see there!
How's the OB-GYN presence here #MedSky?
Been thinking about about the tynelol/autism fiasco and interested in seeing how colleagues in those fields are doing
Been thinking about about the tynelol/autism fiasco and interested in seeing how colleagues in those fields are doing
November 12, 2025 at 1:28 PM
How's the OB-GYN presence here #MedSky?
Been thinking about about the tynelol/autism fiasco and interested in seeing how colleagues in those fields are doing
Been thinking about about the tynelol/autism fiasco and interested in seeing how colleagues in those fields are doing
Reposted by Amir, PharmD
Love it when the newspaper publishes a photo of me with the caption, "Embarrassing and sad."
November 10, 2025 at 9:08 PM
Love it when the newspaper publishes a photo of me with the caption, "Embarrassing and sad."
I don't understand
It's a natural supplement with a natural yellow dye. What do you mean it can - *checks notes*
Cause convulsions, diarrhea, and coma?
www.cspi.org/cspi-news/fd...
#MedSky #RxSky
It's a natural supplement with a natural yellow dye. What do you mean it can - *checks notes*
Cause convulsions, diarrhea, and coma?
www.cspi.org/cspi-news/fd...
#MedSky #RxSky
FDA update: These supplements contain toxic yellow oleander
Nov. 3, 2025: FDA completes list of tejocote root supplements that may contain toxic yellow oleander, which causes severe health risks and may be fatal.
www.cspi.org
November 7, 2025 at 1:10 AM
I don't understand
It's a natural supplement with a natural yellow dye. What do you mean it can - *checks notes*
Cause convulsions, diarrhea, and coma?
www.cspi.org/cspi-news/fd...
#MedSky #RxSky
It's a natural supplement with a natural yellow dye. What do you mean it can - *checks notes*
Cause convulsions, diarrhea, and coma?
www.cspi.org/cspi-news/fd...
#MedSky #RxSky
Reposted by Amir, PharmD
Fewer toddlers developed peanut allergies after guidelines recommended introducing peanut products in infancy, a large primary care registry study showed. 🥜⬇️
October 20, 2025 at 8:17 PM
Fewer toddlers developed peanut allergies after guidelines recommended introducing peanut products in infancy, a large primary care registry study showed. 🥜⬇️
Happy to see the tradition of "robbing the Louvre in the most basic way possible" return.
October 21, 2025 at 12:38 AM
Happy to see the tradition of "robbing the Louvre in the most basic way possible" return.
*Looking over at the US*
"Damn that's fucked up"
*Get email from Ontario grad student union*
"Hey wait a minute"
"Damn that's fucked up"
*Get email from Ontario grad student union*
"Hey wait a minute"
October 17, 2025 at 1:10 PM
*Looking over at the US*
"Damn that's fucked up"
*Get email from Ontario grad student union*
"Hey wait a minute"
"Damn that's fucked up"
*Get email from Ontario grad student union*
"Hey wait a minute"
There's another lesson in polio too. Humor me a bit:
❓What percentage of kids with polio actually went on to develope paralytic poliomyelitis?
A) 5%
B) 12%
C) 0.5%
D) 3%
❓What percentage of kids with polio actually went on to develope paralytic poliomyelitis?
A) 5%
B) 12%
C) 0.5%
D) 3%
September 7, 2025 at 12:08 PM
There's another lesson in polio too. Humor me a bit:
❓What percentage of kids with polio actually went on to develope paralytic poliomyelitis?
A) 5%
B) 12%
C) 0.5%
D) 3%
❓What percentage of kids with polio actually went on to develope paralytic poliomyelitis?
A) 5%
B) 12%
C) 0.5%
D) 3%
In case there's interest: Here's a study on turmeric for OA that's got ok methodology (small though).
I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper.
#Medsky
www.acpjournals.org/doi/10.7326/...
I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper.
#Medsky
www.acpjournals.org/doi/10.7326/...
Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee Osteoarthritis: A Randomized Trial: Annals of Internal Medicine: Vol 173, No 11
Background: Current pharmacologic therapies for patients with osteoarthritis are suboptimal. Objective: To determine the efficacy of Curcuma longa extract (CL) for reducing knee symptoms and effusion–...
www.acpjournals.org
July 16, 2025 at 2:58 PM
In case there's interest: Here's a study on turmeric for OA that's got ok methodology (small though).
I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper.
#Medsky
www.acpjournals.org/doi/10.7326/...
I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper.
#Medsky
www.acpjournals.org/doi/10.7326/...
Reposted by Amir, PharmD
Confessions of a former naturopath.
July 11, 2025 at 12:02 PM
Confessions of a former naturopath.
My version of "don't make me tap the sign"
Interesting to see so much news about measles outbreaks and hospitalization that doesn't even mention its effect on the immune system.
It's not good guys
#MedSky #PharmSky
www.bbc.com/future/artic...
It's not good guys
#MedSky #PharmSky
www.bbc.com/future/artic...
Measles: The race to understand 'immune amnesia'
Scientists have known for years that measles can alter the immune system – but the latest evidence suggests it's less of a mild tweaking, and more of a total reset.
www.bbc.com
June 24, 2025 at 2:43 AM
My version of "don't make me tap the sign"
"That suppository made me bleed out the butt"
"Oh that's terrible I'm sorry. Just to confirm: You took off the foil wrapping before inserting it, right?"
"..."
"Oh that's terrible I'm sorry. Just to confirm: You took off the foil wrapping before inserting it, right?"
"..."
But also the people who answer the phones for the phone numbers on the back of the toothpastes that say “don’t put inside your genitals” (I think they actual say for dental use only) still get calls from people who put toothpaste inside their genitals so fair play I guess
June 18, 2025 at 1:05 PM
"That suppository made me bleed out the butt"
"Oh that's terrible I'm sorry. Just to confirm: You took off the foil wrapping before inserting it, right?"
"..."
"Oh that's terrible I'm sorry. Just to confirm: You took off the foil wrapping before inserting it, right?"
"..."
Reposted by Amir, PharmD
New from The Strain Team:
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
Spinger Nature Discovers MDPI – The Strain on Scientific Publishing
Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro
the-strain-on-scientific-publishing.github.io
June 10, 2025 at 5:49 AM
New from The Strain Team:
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
🎊 Springer Nature Discovers MDPI 🎊
Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).
Gross! 😀 1/n
#ResearchIntegrity #SciPub #AcademicSky
Reposted by Amir, PharmD
The ideal cutoff for adequate time-to-antibiotic delivery in septic shock is being discussed again 🤦♂️
Should we be required to give antibiotics in 1 hr? 3 hr? 15 minutes? 3.14159 minutes?
This is worth a short thread on the background of this topic
Buckle up, it's a mess... #EMIMCC #IDsky #1/6
Should we be required to give antibiotics in 1 hr? 3 hr? 15 minutes? 3.14159 minutes?
This is worth a short thread on the background of this topic
Buckle up, it's a mess... #EMIMCC #IDsky #1/6
a man with a surprised look on his face and the words how did this happen below him
ALT: a man with a surprised look on his face and the words how did this happen below him
media.tenor.com
June 9, 2025 at 12:04 PM
My favorite farsi insult: Namak-nashnaz
Approximate translation: Ungrateful, unappreciative.
Literal translation: One who does not recognize salt 🧂
Devastating in the culinary scene, I'm sure. You're welcome.
Approximate translation: Ungrateful, unappreciative.
Literal translation: One who does not recognize salt 🧂
Devastating in the culinary scene, I'm sure. You're welcome.
June 8, 2025 at 7:48 PM
My favorite farsi insult: Namak-nashnaz
Approximate translation: Ungrateful, unappreciative.
Literal translation: One who does not recognize salt 🧂
Devastating in the culinary scene, I'm sure. You're welcome.
Approximate translation: Ungrateful, unappreciative.
Literal translation: One who does not recognize salt 🧂
Devastating in the culinary scene, I'm sure. You're welcome.
"These things are the ideal way to help people quit smoking!"
⬇️
"Ok there are apparently more kids who use vapes than would have every smoked cigarettes"
⬇️
"Researchers are looking at using smoking cessation drugs to help kids quit vaping"
jamanetwork.com/journals/jam...
Medsky / RxSky
⬇️
"Ok there are apparently more kids who use vapes than would have every smoked cigarettes"
⬇️
"Researchers are looking at using smoking cessation drugs to help kids quit vaping"
jamanetwork.com/journals/jam...
Medsky / RxSky
Varenicline for Youth Nicotine Vaping Cessation
This randomized clinical trial evaluates the efficacy of varenicline plus behavioral counseling, compared with placebo plus behavioral counseling or with enhanced usual care (behavioral counseling alo...
jamanetwork.com
June 4, 2025 at 7:11 AM
"These things are the ideal way to help people quit smoking!"
⬇️
"Ok there are apparently more kids who use vapes than would have every smoked cigarettes"
⬇️
"Researchers are looking at using smoking cessation drugs to help kids quit vaping"
jamanetwork.com/journals/jam...
Medsky / RxSky
⬇️
"Ok there are apparently more kids who use vapes than would have every smoked cigarettes"
⬇️
"Researchers are looking at using smoking cessation drugs to help kids quit vaping"
jamanetwork.com/journals/jam...
Medsky / RxSky
Reposted by Amir, PharmD
Following attacks on humanitarians in Gaza and Sudan, including on Doctors Without Borders staff, the silence is deafening.
No outrage.
No accountability.
@chrislockyear.msf.org, our Secretary General, speaks of the cost for killing humanitarians.
www.doctorswithoutborders.ca/what-is-the-...
No outrage.
No accountability.
@chrislockyear.msf.org, our Secretary General, speaks of the cost for killing humanitarians.
www.doctorswithoutborders.ca/what-is-the-...
What is the cost for killing humanitarians? | Doctors Without Borders / Médecins Sans Frontières (MSF ...
By Christopher Lockyear, secretary general, MSF. Originally published on swissinfo on May 26, 2025. On Saturday, May 3, we at Doctors Without Borders/Médecins Sans Frontières (MSF) woke to shock, gr...
www.doctorswithoutborders.ca
June 2, 2025 at 3:14 PM
Following attacks on humanitarians in Gaza and Sudan, including on Doctors Without Borders staff, the silence is deafening.
No outrage.
No accountability.
@chrislockyear.msf.org, our Secretary General, speaks of the cost for killing humanitarians.
www.doctorswithoutborders.ca/what-is-the-...
No outrage.
No accountability.
@chrislockyear.msf.org, our Secretary General, speaks of the cost for killing humanitarians.
www.doctorswithoutborders.ca/what-is-the-...
Not to be mean but I can't even humour the usual "Why don't you move to the states? You'd make so much more money there!" conversations anymore.
June 1, 2025 at 12:14 AM
Not to be mean but I can't even humour the usual "Why don't you move to the states? You'd make so much more money there!" conversations anymore.
If I can teach one thing to regular folks: Treat supplements with the same caution you treat prescription drugs.
RxSky MedSky
newzsquare.com/rates-of-liv...
RxSky MedSky
newzsquare.com/rates-of-liv...
Rates Of Liver Injuries Rise In The U.S. As Supplements Grow In Popularity
It started with nausea and loss of appetite.
newzsquare.com
May 28, 2025 at 12:17 PM
If I can teach one thing to regular folks: Treat supplements with the same caution you treat prescription drugs.
RxSky MedSky
newzsquare.com/rates-of-liv...
RxSky MedSky
newzsquare.com/rates-of-liv...