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Reposted by Tim Petzold

Chase Bolt @chasebolt.bsky.social · 21d

Our work exploring a new explanation for the regulation of Hoxd genes and the #fin-to-limb transition. 🧪

It was an absolute joy working on this w/ @aurhin.bsky.social and @homeobox.bsky.social @denisduboule.bsky.social @neilshubin.bsky.social

#evo-devo #InHoxWeTrust

How Did Hands Evolve? The Answer Is Behind You.

www.nytimes.com

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Anders Sejr Hansen @andersshansen.bsky.social · 21d

Very interesting new @wbickmor.bsky.social commentary on the mechanistic mystery that is very distal enhancer-promoter interactions www.nature.com/articles/s41...

Is enhancer-driven gene regulation all wrapped up? - Nature Reviews Genetics

In this Comment, Wendy Bickmore discusses mechanistic models of how 3D genome organization facilitates communication between distant enhancers and their target promoters to regulate gene expression.

www.nature.com

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Nature Portfolio @natureportfolio.nature.com · Sep 7

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

This is figure 2, which shows M. ibericus queens lay males from two different species.

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Tim Petzold @timpetzold.bsky.social · Sep 3

Our humble gata2b in situ hybridization image made it onto the cover of @biologyopen.bsky.social!

If you'd like to check out the story behind the image, the link to our new paper is:

journals.biologists.com/bio/article/...

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Tim Petzold @timpetzold.bsky.social · Sep 1

Excited to share that the final version of our work on Connexin 41.8 in HSPC specification is out now in @biologyopen.bsky.social!

If you're curious about how a connexin helps turn endothelial cells into blood stem cells, please have a read!

journals.biologists.com/bio/article/...

Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification

Summary: Cx41.8 is necessary to launch the haemogenic program and induce HSPC formation at the correct time during zebrafish development via a ROS-Hif-Notch-Gata2b pathway.

journals.biologists.com

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Biomedical Picture of the Day BPoD @bpodaily.bsky.social · Aug 18

How the functional architecture of the zebrafish heart is shaped during development

📹 @tobyandrews.bsky.social et al @rashmi-priya.bsky.social
lab @crick.ac.uk in @cellpress.bsky.social Developmental Cell

➡️ bpod.org.uk/archive/2025...

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Toby Andrews @tobyandrews.bsky.social · Aug 6

Thrilled to bits to see our latest work online in Dev Cell! 🥳

We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n

tinyurl.com/cell-stretch

Mechanochemical coupling of cell shape and organ function optimizes heart size and contractile efficiency in zebrafish

Andrews et al. demonstrate that multiscale feedback between mechanical and chemical cues builds a functional heart to support zebrafish embryonic life. Cell recruitment and organ-scale forces drive tr...

tinyurl.com

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Jonathan Eisen @phylogenomics.bsky.social · Aug 8

Got this really cool, ghostly picture by accident the other day in Dillon Beach, CA. It is a Heermann's gull with both it's shadow and reflection.

#birds

Juvenile Heermann's gull (very dark all over) in flight, flying over very very shallow water. Flying to the right maybe two feet off the ground. It's shadow is to the right. Just below the shadow is a reflection on the sheen of water.

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Development @dev-journal.bsky.social · Aug 5

Issue 14 is complete!

On the cover: Drosophila eye imaginal discs stained for the pan-neuronal marker Elav (red or blue) and cell fate-specific markers to investigate basic cell-biological processes such as cell proliferation and morphogenesis during development. See:
doi.org/10.1242/dev.204373

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Nick @gardenwizard.bsky.social · Jul 30

This is my first time seeing a Monarch on our property! I literally just purchased milkweed seeds and began preparing the area I’m going to plant in this fall. That’s quite the synchronicity. #gardening #bugsky #bloomscrolling #photography

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Tim Petzold @timpetzold.bsky.social · Jul 29

Beautiful work using lineage-tracing, transplantation experiments and fate mapping to show that somites give rise to nephron progenitors

www.nature.com/articles/s41...

Somites are a source of nephron progenitors in zebrafish - Nature Communications

This study reveals that cells of the zebrafish kidney can originate from the somites, structures traditionally held as precursors to the skeletal muscle, challenging a century-old paradigm and prompti...

www.nature.com

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Society for Developmental Biology @socdevbio.bsky.social · Jul 25

🐌💫 Snail embryos never looked so fabulous!
Tubulin (white), phospho-histone H3 (pink), and F-Actin (cyan) light up this early stage like a cytoskeletal disco ball.
Image from Clemens Cabernard & Adam von Barnau Sythoff 🪩🧬 #FluorescenceFriday

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JLRay @jlray.bsky.social · Jul 25

Wow. Scientists have edited mosquito DNA to prevent the spread of malaria to humans "while supporting essential physiological functions... and negligible fitness costs" to the mosquito population.

Potentially ending the mosquito-born spread of malaria to humans.

www.nature.com/articles/s41...

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Anna A Monaco @annaamonaco.bsky.social · Jun 23

Mustering the courage to share my latest scicomm endeavour: I channelled my love for writing into a blog where I can hopefully bring the marvels of evolutionary biology and non-coding DNA to all Science lovers!

darkgenomevo.wordpress.com/2025/06/22/i...

It just takes one change

Here, I run though three examples of evolutionary novelty driven by single non-coding DNA changes: limb loss in snakes, gliding in sugar gliders, and coat coloration in African striped mice. These …

darkgenomevo.wordpress.com

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Reposted by Tim Petzold

Axel Visel @axelvisel.bsky.social · Jul 16

No new genes needed to fly - just rewire what you have! 🦇🧬

Great new paper from the labs of @fany-real.bsky.social @stemundi.bsky.social @dariloops.bsky.social

doi.org/10.1038/s415...

#EvoDevo #SingleCell #BatWings

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Journal of Experimental Biology @jexpbiol.bsky.social · Jun 26

In her Perspective, Emilie Snell-Rood discusses the value of basic science, using the Morpho butterfly as an example of how this type of research has driven later innovation & highlights the value of government and institutional support for basic research

journals.biologists.com/jeb/article/...

A photo of six butterflies which depicts the many different colours and patterns of butterflies in the genus Morpho. The top left is Morpho menelaus, the top middle is Morpho helenor, the top right is Morpho cypris. On the bottom left is Morpho rhetenor, the bottom middle is Morpho sulkowskyi, and the bottom right is Morpho hecuba. Photo credit: Emilie Snell-Rood.

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Daniel Castranova @zebrafish007.bsky.social · Nov 11

The first 22 hours of #Zebrafish development. Blood vessels labeled in green #WeinsteinLab 🔬🧪

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Rory Cooper @rorylcooper.bsky.social · Jun 4

Excited to share our new research in @cp-iscience.bsky.social! We reveal that tortoise head scales are sculpted through two distinct developmental processes - chemical signalling and mechanical folding 🐢🔬🧪
@lanevol.bsky.social @genevunige.bsky.social

www.cell.com/iscience/ful...

Chemical and mechanical patterning of tortoise skin scales occur in different regions of the head

Biological sciences; Zoology; Evolutionary biology

www.cell.com

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Antoine Zalc @antoinezalc.bsky.social · Jun 4

www.nature.com/articles/s41...

Dev bio is amazing !!

Maternal iron deficiency causes male-to-female sex reversal in mouse embryos - Nature

Iron-deficient conditions in pregnant mice can cause XY mouse embryos to develop female rather than male genitalia, revealing that iron metabolism has a role in determining male sex in mice.

www.nature.com

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Arnau Sebé-Pedrós @arnausebe.bsky.social · May 7

Check out our latest work on the evolution of animal genome regulation out today in @nature.com. Nicely summarized below by @ianakim.bsky.social.
www.nature.com/articles/s41...

This is a major output from our ERC-StG project Evocellmap @erc.europa.eu at @crg.eu

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Communications Biology @commsbio.nature.com · May 15

A review emphasizes the advantages of using zebrafish in research, outlines key differences in experimental approaches, and offers guidelines for designing studies in a way that enhances experimental rigor and reproducibility. www.nature.com/articles/s42...

Zebrafishology, study design guidelines for rigorous and reproducible data using zebrafish - Communications Biology

A review emphasizes the advantages of using zebrafish in research, outlines key differences in experimental approaches, and offers guidelines for designing studies in a way that enhances experimental ...

www.nature.com

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Shane Herbert @shaneherbert.bsky.social · May 6

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...

Interphase cell morphology defines the mode, symmetry, and outcome of mitosis

During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...

www.science.org

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Zebrafish Rock! @zebrafishrock.bsky.social · Apr 24

Look familiar? This beautiful video of #zebrafish embryogenesis was used for a 'one-frame per page' flipbook in the December 1996 edition of @dev-journal.bsky.social. Credit to Rolf Karlstrom and Don Kane. #ZebrafishFunFacts 🧪

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Arnaud Martin @evolvwing.bsky.social · Apr 14

Awesome new paper by @lucalivraghi.bsky.social et al.
doi.org/10.1016/j.cu...
in @currentbiology.bsky.social
on the evo-devo of a butterfly color variation

enjoy the show!

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Rory Cooper @rorylcooper.bsky.social · Apr 9

Thrilled that our image was selected for the cover of @royalsocietypublishing.org's Open Biology! We experimentally induced a developmental shift from normal footpad scales to mechanically-driven folding on chicken embryo digits 🐣🔬. Stay tuned—the full article is coming soon! 🧪 #DevBio

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