Daniel Castranova
@zebrafish007.bsky.social
1.7K followers 1.7K following 53 posts
Zebrafish, blood and lymphatic vessels, microscopes, imaging, aquaculture, cavefish, 3D printing, science. views my own.
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zebrafish007.bsky.social
The first 22 hours of #Zebrafish development. Blood vessels labeled in green #WeinsteinLab 🔬🧪
Reposted by Daniel Castranova
retof.bsky.social
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
Reposted by Daniel Castranova
solomonrdavid.bsky.social
You’re not ready for gar slime:
Reposted by Daniel Castranova
scadsai.bsky.social
@scadsai.bsky.social training coordinator @haesleinhuepf.bsky.social provided insights into his professional career in the podcast series “The Microscopists.”
If you want to know why he'll never ask biologists for better images again, click here:
🍍 themicroscopists.bitesizebio.com/episodes/rob...
Reposted by Daniel Castranova
dev-journal.bsky.social
Wrong place, right time: Eda drives ectopic teeth formation in fish
This Research Highlight showcases the work from Tyler Square and colleagues: journals.biologists.com/dev/article/...
Eda overexpression causes precocious tooth differentiation in sticklebacks. (A,B) at 9 dpf, Eda OE fish (n=9) demonstrated precocious oral tooth germs relative to control fish (n=10). Images show eGFP from the dlx2b tooth reporter and mCherry from the OE transgene. A’ and B’ show the fish indicated in A and B in greater detail. Black arrowheads indicate pioneer tooth germs. (C) at 12 dpf in WT, pairs of germs are observed on the premaxilla and dentary (black arrowheads), similar to the condition seen in the 9 dpf Eda OE fish, suggesting these represent accelerated endogenous teeth. Sale bars=100 μm.
Reposted by Daniel Castranova
akankshi.bsky.social
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
Reposted by Daniel Castranova
pedroprocha.bsky.social
🚨🚨🚨 Please repost
We are looking for postdocs to join our lab at NIH.
Apply:
www.nichd.nih.gov/research/atNICHD/Investigators/rocha/apply
Learn more about training at NIH :
www.training.nih.gov/research-tra...
Job add showing the lab logo and the following text: 
WHAT WE OFFER
Fully-funded fellowships up to five years  Opportunity to start your own research program or lead ongoing projects.
Large, diverse and extraordinary scientific network at the NIH/Bethesda campus. 

Working at NIH offers the possibility of living in a diverse, liberal and vibrant city: Washington DC
Or in a calm residential area with great schools and good affordable housing: Bethesda and Rockville.
 
WHO YOU ARE
You share our enthusiasm for epigenetics, gene regulation, nuclear organization and mouse development. You have PhD-experience in one or more of the following: mouse development, mouse genetics, epigenetics, or computational biology.
Reposted by Daniel Castranova
whitefishlab.bsky.social
Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2
Reposted by Daniel Castranova
karinayaniv.bsky.social
Happy to see our work, led by @ivanbassi.bsky.social, out today in @jem.org! #Zebrafish help us find new treatments for a #rare_disease affecting #lymphatic vessels! Congrats to all authors and thanks to #MDBRide4Rare, #ODC_UPenn, @erc.europa.eu for support @weizmanninstitute.bsky.social
jem.org
Bassi et al. @karinayaniv.bsky.social @weizmanninstitute.bsky.social use #zebrafish to help identify new treatments for a severe lymphatic malformation. rupress.org/jem/article/...

#CardiovascularBiology #HumanDiseaseGenetics
Reposted by Daniel Castranova
daniellebeckman.bsky.social
Check this neuron infected with #SARSCoV2 being attacked by a microglia. Is this process beneficial or detrimental? Do we want therapies to inhibit microglia activation/neuroinflammation, but what if it means more neurons infecting other neurons? Neurovirology is fascinating! #FluorescenceFriday
zebrafish007.bsky.social
💯
ritastrack.bsky.social
Microscopy most especially. To be the first human to ever lay eyes on something. What a feeling.
redpenblackpen.bsky.social
Really just had something like this feeling this afternoon. It’s the high that keeps you coming back for more
Reposted by Daniel Castranova
hankgreen.bsky.social
mRNA tech is some of the coolest, most powerful, most promising scifi shit humans are currently doing. They are being investigated to help with cancers, autoimmune diseases, M.S., stroke recovery, heart disease, diabetes, arthritis, and high cholesterol.
Reposted by Daniel Castranova
fsantoriello.bsky.social
New short story from my postdoc in the Bassler lab is up on bioRxiv!

Turns out our favorite quorum sensing responsive phage VP882 is a member of a larger family of phages that is distributed across multiple bacterial species and can eavesdrop on a universally conserved autoinducer.

#PhageSky 🦠🧫
biorxiv-microbiol.bsky.social
A family of linear plasmid phages that detect a quorum-sensing autoinducer exists in multiple bacterial species https://www.biorxiv.org/content/10.1101/2025.07.30.667625v1
Reposted by Daniel Castranova
jeffreyafarrell.bsky.social
Hey friends - Daniocell is experiencing a temporary outage right now. The NICHD server it is hosted on got dropped from the NIH’s firewall list & so currently can’t be accessed outside the NIH. The relevant IT teams are working to resolve it. Sorry for any inconvenience. It’ll be back soon!!
Reposted by Daniel Castranova
hankgreen.bsky.social
I doubt that there is a single family in America that hasn’t benefitted directly from the NIH.
Reposted by Daniel Castranova
goetzjacky.bsky.social
💥 Paper accepted (in principle) #cellfie 🤩
A long wait, a beautiful project, some amazing collaborations.
Stay tuned for more !
ALT : how cells (and cell-like beads) are deformed in constraining vessels
Reposted by Daniel Castranova
currentbiology.bsky.social
Our latest issue is now live! On the cover is a species of Asian noodlefish characterized by their transparency due to the absence of red blood cells, slender bodies and scaleless skins, and a poorly ossified skeleton. www.cell.com/current-biol...
Reposted by Daniel Castranova
daniellebeckman.bsky.social
I might be a bit obsessed with blood vessels in the brain 🤓! Aren't they pretty? And check the red blood cells inside the small ones!
Is it okay if I keep advertising our call for papers using more images of blood vessels in the brain? 😜🔬
#dementia #WomenInStem
With @natureportfolio.nature.com
Microscopy image of blood vessels in the brain
Reposted by Daniel Castranova
zebrafishrock.bsky.social
Galaxy of microtubules in the embryonic zebrafish eye. Credit to @zebrafish007.bsky.social. #ZebrafishZunday 🧪
Confocal image of a transgenic zebrafish embryo. The transgene is Tg(XlEef1a1:dclk2-GFP)io008, made by the Mione Lab, labels microtubules.
Reposted by Daniel Castranova
gauthamsankara.bsky.social
The cell looks like Inkay Pokémon🔬 — yellow glowing arms, pink heart.
Under attack by cyan bacteria🦠, but it’s just vibing on the glass, dancing🪩, unaware of the aftermath☠️. #FluorescenceFriday #Microscopy #CellBiology #mechanobiology @pasteuredu.bsky.social #hostpathogeninteraction @pasteur.fr
Reposted by Daniel Castranova
zebrafishrock.bsky.social
Development of a transgenic zebrafish embryo. Credit to Dr. Mario Mendieta-Serrano. #ZebrafishZunday 🧪
Reposted by Daniel Castranova
chrmosimann.bsky.social
Why wait for #FluorescenceFriday if you can have a neat #zebrafish right now.
(pic credit Amanda Garfield @cudevbio.bsky.social) #devbio