Ulad Litvin
@ulad-litvin.bsky.social
92 followers
140 following
7 posts
PhD student (MRC-UofG CVR)
🏰 antiviral defence | 🧬 evolution | 🔮 protein structure prediction
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Reposted by Ulad Litvin
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Reposted by Ulad Litvin
Reposted by Ulad Litvin
Reposted by Ulad Litvin
Joe Grove
@grovearmada.bsky.social
· Aug 26
Jon Mifsud
@jonathonmifsud.bsky.social
· Aug 25
Recent advances in the inference of deep viral evolutionary history | Journal of Virology
Phylogenetic studies examining the origins, emergence, and spread of viruses have arguably been one of the most active and successful areas of evolutionary biology and form the bedrock of the flourishing field of genomic epidemiology. This, in part, reflects the ability of viruses, particularly those with RNA genomes, to evolve at rates much greater than their cellular counterparts (1). The rapid rate at which viruses evolve and accumulate mutations enables evolutionary signals to be identified through comparative genomics at short timescales relevant for outbreak investigation and response. The integration of phylogenetics and epidemiology, known as phylodynamics, has become a vital tool in response to numerous viral outbreaks, epidemics, and pandemics, including Ebola (2), Zika (3), and, more recently, COVID-19 (4) and mpox (5).
journals.asm.org
Reposted by Ulad Litvin
Reposted by Ulad Litvin
Nate Corley
@ncorley.bsky.social
· Aug 15
Accelerating Biomolecular Modeling with AtomWorks and RF3
Deep learning methods trained on protein structure databases have revolutionized biomolecular structure prediction, but developing and training new models remains a considerable challenge. To facilita...
www.biorxiv.org
Reposted by Ulad Litvin
Reposted by Ulad Litvin
Franklin Nobrega
@fnobrega.bsky.social
· Jul 28
Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites
Zhang, Todeschini, and Wu et al. show that the bacterial defense system Kiwa senses
phage attachment at the membrane and assembles a transmembrane complex that halts
infection by blocking phage DNA re...
www.cell.com
Reposted by Ulad Litvin
Reposted by Ulad Litvin
Frank Noe
@franknoe.bsky.social
· Jul 10
Reposted by Ulad Litvin
Reposted by Ulad Litvin