Greifflab
@victorgreiff.bsky.social
2.7K followers 860 following 18 posts
Professor of Computational and Systems Immunology @UniOslo. Cofounder & Director of Computational Immunology @imprintlabs.bsky.social
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victorgreiff.bsky.social
Extremely pleased to share our new work in collaboration with the @bruskolab.bsky.social lab, where we leveraged one of the largest TCRbeta sequencing datasets to identify T1D-associated TCR-based signatures. Paper link and 🧵 are below. Incredible work led by @puneet021192.bsky.social.
puneet021192.bsky.social
Happy to share our new collaborative work! 🚨 We analyzed 2250 TCR repertoires to uncover how HLA risk alleles shape immune autoreactivity in T1D. T1D-specific HLA-motifs were also validated in pancreatic lymph nodes (pLN) & spleen. 🧬🧵 #T1D #Immunology #TCR 1/9
victorgreiff.bsky.social
We’re recruiting a PhD Fellow in Computational Systems Immunology. Work on large-scale immune receptor datasets and develop computational models in close collaboration with experimental labs. Apply here: www.jobbnorge.no/en/available...
PhD Fellowship in Computational Systems Immunology (286608) | University of Oslo
Job title: PhD Fellowship in Computational Systems Immunology (286608), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025
www.jobbnorge.no
Reposted by Greifflab
amelierocks.bsky.social
Deadline extended - last chance, second edition!
amelierocks.bsky.social
Last chance to register for the 2025 European RosettaCon - we had a blast last year, and @ajasjaljubetic.bsky.social is putting together a great program. With Easter eggs 🥚 in the submission system!
A very literal and nerdy illustration of protein walkers: alpha helices on the bottom, AT-ATs walking on them
Reposted by Greifflab
imprintlabs.bsky.social
Earlier this year, Imprint came out of stealth on the TED Mainstage to share our vision:

What if the immune system holds the key to curing chronic diseases—and we just need the tools to read it?

We’re building those tools.
Our TED talk is now live 👉 go.ted.com/beckbrachman
go.ted.com
Reposted by Greifflab
typaslab.bsky.social
EMBL is back on hiring faculty! Check out the multiple open positions:

3 PIs- 2 in Heidelberg incl. our Molecular Systems Biology Unit, 1 in Grenoble
1 Head of Unit (Cell Biology & Biophysics, Heidelberg).

Closing deadlines in Sep!
+3 more positions to come out then, stay tuned...
@embl.org
embl.org
EMBL @embl.org · Aug 7
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠

Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.

Take a look at these four open positions 👇
victorgreiff.bsky.social
Excited to co-found and help lead @imprintlabs.bsky.social —a focused effort to decode the immune system’s memory through cutting-edge computation and experimentation. Grateful to be on this journey with an exceptional team.
imprintlabs.bsky.social
🧵 Today, IMPRINT, a pioneering new nonprofit initiative, is announcing $15 million in philanthropic funding to advance our work to decode the body's immune memory and uncover the causes of chronic diseases.

#Immunology #Biotech #BiotechResearch
Press Release May 2025 — Imprint FRO
Imprint FRO launches with $15M in funding
www.imprint.org
Reposted by Greifflab
immunebjorn.bsky.social
We have available a 3-year postdoc position in Bioinformatics in our lab at the University of Oslo focusing on the adaptive immune response in rheumatoid arthritis. Please see details here
lds.easycruit.com/vacancy/3490...
Lovisenberg Diakonale Sykehus
Postdoctoral research fellowship in Bioinformatics and Immunology (3-year, full-time)
lds.easycruit.com
Reposted by Greifflab
imprintlabs.bsky.social
Looking for a job in immunology or biotech research?
✨IMPRINT is #hiring! ✨

Join us to help revolutionize how we decode the body’s immune memory, uncover the causes of chronic diseases, and drive breakthroughs in autoimmunity and neuropsychiatric research.

#BiotechJobs #Immunology #sciencejobs
Jobs — Imprint FRO
Join our team—current openings at Imprint
www.imprint.org
Reposted by Greifflab
franknoe.bsky.social
The BioEmu-1 model and inference code are now public under MIT license!!!

Please go ahead, play with it and let us know if there are issues.

github.com/microsoft/bi...
Reposted by Greifflab
baym.lol
This paper has been a long time coming: We looked at the genomes of historical bacterial samples over a century to look for trends of antibiotic resistance genes, finding multiple instances of them in infections before the age of antibiotics, but an increase in both frequency and mobility after
biorxiv-microbiol.bsky.social
Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics https://www.biorxiv.org/content/10.1101/2025.01.16.633422v1
Reposted by Greifflab
elisarosix.bsky.social
1/10 Small pre-Christmas #bluetorial on the workshop held by the T-cell Receptor (TR) and Immunoglobulin (IG) Nomenclature Sub-Committee of @iuis-online.bsky.social on policies and procedures for TR/IG gene annotation and nomenclature #immunerepertoire #immunogenetics
Reposted by Greifflab
lindorfflarsen.bsky.social
A periodic reminder that biologically meaningful conformational changes do not have to be large

While textbooks may indicate that relevant motions are large, even the original paper on alternating access makes it clear that atoms just need to move a bit to have an effect. doi.org/10.1038/2119... 🧬🧶
Figure from the paper describing the alternating access model and text that says that relevant motions can be exceedingly subtle
victorgreiff.bsky.social
Extremely pleased to share our new work in collaboration with the @bruskolab.bsky.social lab, where we leveraged one of the largest TCRbeta sequencing datasets to identify T1D-associated TCR-based signatures. Paper link and 🧵 are below. Incredible work led by @puneet021192.bsky.social.
puneet021192.bsky.social
Happy to share our new collaborative work! 🚨 We analyzed 2250 TCR repertoires to uncover how HLA risk alleles shape immune autoreactivity in T1D. T1D-specific HLA-motifs were also validated in pancreatic lymph nodes (pLN) & spleen. 🧬🧵 #T1D #Immunology #TCR 1/9
Reposted by Greifflab
puneet021192.bsky.social
Happy to share our new collaborative work! 🚨 We analyzed 2250 TCR repertoires to uncover how HLA risk alleles shape immune autoreactivity in T1D. T1D-specific HLA-motifs were also validated in pancreatic lymph nodes (pLN) & spleen. 🧬🧵 #T1D #Immunology #TCR 1/9
Reposted by Greifflab
pmeysman.bsky.social
Our massive effort to recontextualize #single #T-cell data is now out in Science Advances! We developed a new system, STEGO, to do a TCR-first analysis, and reanalyzed 12 studies and more than 500 000 individual T-cells.
Supported by @cziscience.bsky.social !
doi.org/10.1126/scia...
T cell receptor–centric perspective to multimodal single-cell data analysis
T cell receptor–centric perspective improves single-cell analysis.
doi.org
Reposted by Greifflab
helenajambor.bsky.social
Hey academics, what is happening with the preprint sites? 🧪 help..

@bioarxiv : reject (no biological data, no surprise)
@arxiv_bio: 3 weeks turnaround!
OSF preprint: 1 week, no approval yet 😮 - do they need help?