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Reposted by Viktoria Flore

Dominik Vonficht @dom60.bsky.social · Aug 13

Excited to share the latest publication from my PhD with @simonhaas.bsky.social at @dkfz.bsky.social, out now in Nature Methods!

A big thanks to all co-authors, especially Lea Jopp-Saile, Schayan Yousefian and @viktoriaflore.bsky.social for all their hard work.
www.nature.com/articles/s41...

Ultra-high-scale cytometry-based cellular interaction mapping - Nature Methods

Interact-omics, a high-throughput cytometry-based framework, resolves the cellular interaction landscape.

www.nature.com

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Viktoria Flore @viktoriaflore.bsky.social · Aug 10

Thank you, sure!

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Viktoria Flore @viktoriaflore.bsky.social · Aug 8

Thank you Charles!

Reposted by Viktoria Flore

Max Delbrück Center @mdc-berlin.bsky.social · Aug 7

🧬 How do immune cells talk – and what happens when they don’t?

A new technology by Simon Haas & Daniel Hübschmann maps millions of cell contacts 🔬
It shows how immune responses shift in disease & therapy.

📊 A step toward personalized medicine!

🔗 Read more: www.mdc-berlin.de/news/press/h...

Two immune cells interacting with glowing connection, illustrating cell communication.

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Reposted by Viktoria Flore

Deutsches Krebsforschungszentrum (DKFZ) @dkfz.bsky.social · Aug 7

Ein Team aus Forschenden vom BIH, @mdc-berlin.bsky.social, DKFZ, HI-STEM und @qmul.bsky.social hat eine Technologie zur Entschlüsselung der Immunzell-Kommunikation entwickelt. Damit lässt sich unter anderem ablesen, warum Immuntherapien bei manchen Menschen wirken bei anderen nicht.
t1p.de/w3v16

Wie Immunzellen kommunizieren, um Krankheiten und Krebs zu bekämpfen

Ein interdisziplinäres Team aus Wissenschaftlerinnen und Wissenschaftlern vom Berlin Institute of Health in der Charité (BIH), vom Max Delbrück Center, dem Deutschen Krebsforschungszentrum (DKFZ), dem...

t1p.de

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Reposted by Viktoria Flore

Simon Haas @simonhaas.bsky.social · Aug 7

Excited to share our latest paper @natmethods.nature.com
We present a high-throughput framework to map cellular interactions at ultra-high scale – broadly applicable from whole-organism immune response mapping to personalized therapy response prediction (1/4).
www.nature.com/articles/s41...

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Viktoria Flore @viktoriaflore.bsky.social · Aug 7

Huge thanks to my co-first authors @dom60.bsky.social, Lea Jopp-Saile, and Schayan Yousefian for the incredible teamwork, and of course to @simonhaas.bsky.social and Daniel Hübschmann for the invaluable support and guidance! (4/4)

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Viktoria Flore @viktoriaflore.bsky.social · Aug 7

The computational workflow we developed to analyze the physically interacting cells is available as an open-source R package 📦
Check it out here: github.com/agSHaas/PICtR and let me know what you think! (3/4)

GitHub - agSHaas/PICtR: Analysis of physically interacting cells (PICs) in flow cytometry data using R

Analysis of physically interacting cells (PICs) in flow cytometry data using R - agSHaas/PICtR

github.com

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Viktoria Flore @viktoriaflore.bsky.social · Aug 7

Our framework can map millions of cells and their physical interactions using flow cytometry - even in existing datasets. We show how these interaction maps can help predict responses to immunotherapies and unravel immune cell communication during infections 🦠 (2/4)

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Viktoria Flore @viktoriaflore.bsky.social · Aug 7

Did you ever wonder what insights hide in the multiplets that are usually discarded in flow cytometry? 🫧 Find out in the first publication of my PhD, now out in Nature Methods! www.nature.com/articles/s41... (1/4)

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Reposted by Viktoria Flore

Mario Livio @mariolivio.bsky.social · Jun 25

Today is June 25. On this date in 1903 Marie Curie defended her doctoral thesis on radioactive substances at Université de la Sorbonne in Paris, becoming 1st woman in France to receive a doctoral degree. Image shows the thesis cover.

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Viktoria Flore @viktoriaflore.bsky.social · Jun 13

Thank you to everyone who helps make this such a great place to do research, and to @jungeakademie.bsky.social and @volkswagenstiftung.de for the initiative to highlight the scientists and leadership behind inspiring research environments 🔬🧬👩‍🔬

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Viktoria Flore @viktoriaflore.bsky.social · Jun 13

So proud that the Single Cell Focus Area was selected as one of the winners of the "Best Research Environment 2024" award!

Max Delbrück Center @mdc-berlin.bsky.social · Jun 12

💡 Great science needs great environments. We are proud that our Single Cell Focus Area is among the ten “Best Research Environments 2024” – selected by @jungeakademie.bsky.social‬ together with the @volkswagenstiftung.de. Congratulations! 🥳

More details:
👉 www.diejungeakademie.de/en/press/bes... 👈

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Reposted by Viktoria Flore

Die Junge Akademie @jungeakademie.bsky.social · Jun 8

🏆 Die 10 Gewinnerteams des Preises „Bestes #Forschungsumfeld 2024“ stehen fest! Aus fast 300 Bewerbungen wurden sie aus einer beeindruckenden Shortlist per Los gezogen. Wir gratulieren gemeinsam mit der @volkswagenstiftung.de! 🎉
Wer gewonnen hat? 👉 www.diejungeakademie.de/de/presse/be...

Gruppenbild mit frühlichen Menschen. Foto: Die Junge Akademie/Bernd Brundert

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Viktoria Flore @viktoriaflore.bsky.social · Jun 4

Excited to see our team among the finalists for the Best Research Environment award by the Junge Akademie! Fingers crossed for the draw 🤞

Die Junge Akademie @jungeakademie.bsky.social · Jun 4

🧬Unter den Top 24 der besten Forschungsumfelder ist auch die Single #Cell Focus Area. Sie vereint die Forschung der Charité Berlin, des @bihatcharite.bsky.social, des @mdc-bimsb.bsky.social und des @mdc-berlin.bsky.social. Der Preis wird im Juni ausgelost.
👉 www.diejungeakademie.de/de/projekte/...

Das Gruppenfoto zeigt 45 Personen auf einer Holzterrasse vor einer Straße, Palmen und dem Meer.
Bildrechte bei Ashley Sanders, MDC

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Reposted by Viktoria Flore

Daniel Lipka @dblipka.bsky.social · Apr 8

Hey #HemeSky and #EpiSci folks! We are hiring!
For our Translational Cancer Epigenomics team @dkfz.bsky.social and @nct-heidelberg.bsky.social we are looking for a talented postdoc interested in research on heme malignancies and #epigenetics.
Interested?
👉See jobs.dkfz.de/en/jobs/1676... or DM me!

Postdoctoral Researcher

jobs.dkfz.de

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Viktoria Flore @viktoriaflore.bsky.social · Apr 4

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Reposted by Viktoria Flore

Cell - a Cell Press journal @cp-cell.bsky.social · Mar 31

Now online! Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

Adjusting the timing of stem cell infusion can reduce the incidence and severity of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. The rhythmic fluctuations in inflammation levels before infusion dictate subsequent T cell responses, which may be a key factor underlying outcomes based on the time of day that transplantation occurs.

dlvr.it

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Reposted by Viktoria Flore

Alexandra Witze @alexwitze.bsky.social · Mar 27

We polled Nature readers to ask if they were thinking of leaving the US for jobs abroad. Three-quarters of them (who said they were US-based scientists) said yes. 🧪

www.nature.com/articles/d41...

75% of US scientists who answered Nature poll consider leaving

More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

www.nature.com

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Roychoudhuri Lab @roychoudhurilab.bsky.social · Mar 5

Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U

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Europe PMC @europepmc.org · Mar 11

Hey #LifeScience community have you seen that @altmetric.com now includes Bluesky as attention source 🎉

Bluesky is becoming a great place to share research and engage in scientific discussions! 🔬💬

#AcademicChatter #AcademicSky #AcademicBluesky #SciComm #ECRChat #PhDSky #MedSky

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Reposted by Viktoria Flore

bioRxivpreprint @biorxivpreprint.bsky.social · Mar 11

🎉 bioRxiv & medRxiv are now managed by openRxiv, a new independent nonprofit. This transition allows for more flexibility and innovation. Our mission remains being a free service to authors ensuring rapid sharing of scientific information before peer review.
ℹ️ openrxiv.org/introducing-...

Introducing openRxiv: a new independent home for preprint sharing in the life sciences - openRxiv

We’re thrilled to announce the launch of openRxiv as an independent nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences. openRxiv ensures that r...

openrxiv.org

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Reposted by Viktoria Flore

Science Magazine @science.org · Mar 11

A special issue on #WomensHealth in #ScienceAdvances highlights a growing wave of research focusing on women’s unique biological and psychological experiences.

Learn more: scim.ag/3R59fPe (THREAD 🧵)

Science Advances’ special issue on women’s health highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Articles cover a range of studies from the interplay between menopause and Alzheimer’s risk to the menstrual cycle’s influence on the brain-heart connection. It also describes the opportunities pregnancy provides to research aspects of both physical and mental health. By prioritizing women’s unique physiological and psychological experiences, research can expand the frontiers of knowledge in ways that benefit everyone.

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Reposted by Viktoria Flore

Etienne Bucher 🌾🧬🇪🇺 @plantepigenetics.ch · Mar 2

As we can expect PubMed dysfunction more and more or to be swamped with fake journals I suggest you get acquainted to this nice alternative: europepmc.org

Europe PMCHome - Europe PMC

Europe PMC is an archive of life sciences journal literature.

europepmc.org

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Reposted by Viktoria Flore

Simon Haas @simonhaas.bsky.social · Feb 8

Great teamwork with co-lead Niels Weinhold (@HDMyeloma) and a fantastic effort led by Raphael Lutz, Alexandra Poos, Llorenç Solé Boldo, Lukas John, and many others. Grateful for such an incredible team! 👏 #TeamScience 2/2

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