This year’s Nobel Prize in Physiology or Medicine has been awarded to Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi for discovering a class of immune cells that help to prevent the body from attacking its own tissues. #medsky 🧪

“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.”
― Jane Goodall

💙 RIP to a real one. My childhood hero

Thank you, Andi😊!

Excited to share the preprint from my postdoc work @ellenberglab.bsky.social! 🌟
During mitotic exit, cells rebuild thousands of nuclear pores within minutes. How do tiny holes expand to selective channels, and how is this coordinated with the nuclear envelope remodeling? 🔗 doi.org/10.1101/2025...

Curious about RNA, aptamers, lipid membranes, molecular dynamics simulations, synthetic cells - and how these topics come together? Join @floppleton.bsky.social's talk in the unano webinar blogs.ed.ac.uk/unanowebinars

If you are thinking about the future of structural biology, we are too! Our two cents (Jürgen Plitzko and I) just got published online here: authors.elsevier.com/sd/article/S...

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

Today in @nature.com we share our back-to-back stories with Ning Zheng’s lab revealing chemical-genetic convergence between a molecular glue degrader & E3 ligase cancer mutations. 1/5

Here's how to predict binding of tens or hundreds of small molecules to protein assemblies using Boltz 2 in ChimeraX.
Accuracy depends on how similar the ligands and binding pockets are to existing experimental structures.
www.rbvi.ucsf.edu/chimerax/dat...

🧪 Open PhD or Postdoc position 🧪
The project is in collaboration with my new collegue Miha Modic. If you are interesed in RNA modification, centromeres and bioinformatics this is for you!
Miha has more positions to fill, infos on his linkedin: linkedin.com/in/miha-modic-9aa8a752.

Finally out in Nature Chem Bio:
SNAP-tag2 for faster and brighter protein labeling
www.nature.com/articles/s41...
Thank you Steffi and Veselin.

Static structures are out. A new publication from the Ellenberg lab ( @ellenberglab.bsky.social, @embl.org , @sfb1638.bsky.social ) and Andrej Sali shows how integrative spatiotemporal modeling captures molecular motion in 4D, unlocking dynamic views of nuclear pore complex assembly.

Did you know that DNA must form overlapping loops to give rise to the well-known X-shape of chromosomes? 🧬🧪

New research from EMBL's Ellenberg Group provides new insights into the process of chromosome formation.

@ellenberglab.bsky.social
@andibrunner.bsky.social

www.embl.org/news/science...

🚨 Exciting Opportunity Alert! 🚨

The Ellenberg Lab is #hiring for two incredible postdoc/research scientist positions! Join the ERC-funded MITOFOLD project! 🧬

If you’re passionate about cutting-edge research and want to make a real impact, this is your chance! 🚀

My first own project is published:

Despite major differences in chromosome shape during #interphase and #mitosis, the underlying #loop-extruder based organization is highly similar

A new data resource and new insights into human chromatin biology! 🧬🥳