Sven Klumpe
@svenklumpe.bsky.social
1.4K followers 990 following 100 posts
CryoFIB Development and In situ structural biology. NPC and TE enthusiast. Drosophilist but ready to switch to wherever biology takes us Getting to enjoy science with a group at IMBA/IMP of the Vienna BioCenter https://www.imp.ac.at/groups/sven-klumpe
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svenklumpe.bsky.social
Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @cellcellpress.bsky.social www.cell.com/cell/fulltex.... What’s new?
svenklumpe.bsky.social
So good I’m almost worried it is fake but anyhow an amazing message to start the week to 😊
kojamf.bsky.social
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
Reposted by Sven Klumpe
impvienna.bsky.social
🎉Congrats to our @vdeneke.bsky.social, postdoc in the @pauligroup.bsky.social, who has received the 2025 Life Sciences Research Award Austria from the ÖGMBT!

She's recognised for her groundbreaking work on the molecular mechanisms of fertilisation: www.imp.ac.at/news/article...
Reposted by Sven Klumpe
pauligroup.bsky.social
Congratulations to @vdeneke.bsky.social & Andreas Blaha @impvienna.bsky.social for their research on vertebrate fertilization, which was awarded this year's ÖGMBT Life Science Research Award in Austria for basic research!
impvienna.bsky.social
🎉Congrats to our @vdeneke.bsky.social, postdoc in the @pauligroup.bsky.social, who has received the 2025 Life Sciences Research Award Austria from the ÖGMBT!

She's recognised for her groundbreaking work on the molecular mechanisms of fertilisation: www.imp.ac.at/news/article...
Reposted by Sven Klumpe
olibclarke.bsky.social
Initial attempt at replicating in relion (parameters in next post). This is for Aca2-RNA, using a 100k subset of the 2D-classified particles (no prior 3D cleanup).

A 1-class ab initio in relion, then local refinement in relion (1.8deg searches+blush) gives a nominally 3.3Å map; 3.5 Å w/out blush.
Reposted by Sven Klumpe
computingcaitie.bsky.social
I am excited to share our new preprint on the CAGE complex, a mysterious hollow protein complex that I first saw years ago while surveying Tetrahymena ciliary lysate www.biorxiv.org/content/10.1... #cilia #protistsonsky 🧬🧪
Reposted by Sven Klumpe
olibclarke.bsky.social
This one is a bit of a departure from the usual and definitely a work in progress!

We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.

Read on for details... 1/x
Reposted by Sven Klumpe
cellarchlab.com
BIG NEWS!! We will be hiring a new professor with 25 years of endowed funding at the @biozentrum.unibas.ch @unibas.ch, focused on using biophysics and structural biology to explore climate-related fundamental science topics. Come start an innovative research cluster with us! 🧪🔬🧶🧬🌾🌍
unibas.ch
The University of Basel is setting up a new endowed professorship at the @biozentrum to make fundamental discoveries at the interface between biophysics and climate-relevant environmental biology. This will be made possible by the Georg H. Endress Foundation.
New endowed professorship strengthens climate research at the University of Basel
The University of Basel is setting up a new endowed professorship at the Biozentrum to make fundamental discoveries at the interface between b...
www.unibas.ch
svenklumpe.bsky.social
Yes, he definitely has a unique style :)
svenklumpe.bsky.social
JP’s an artist! :)
svenklumpe.bsky.social
Yep, JPs the artist behind it!
Reposted by Sven Klumpe
laurajohansen.bsky.social
+1 would sign - I used FlyBase *regularly* for my undergrad thesis on Drosophila genetics!
svenklumpe.bsky.social
If you are thinking about the future of structural biology, we are too! Our two cents (Jürgen Plitzko and I) just got published online here: authors.elsevier.com/sd/article/S...
svenklumpe.bsky.social
+1 would sign. @flybase.bsky.social is truly essential!
svenklumpe.bsky.social
So awesome this is out in its final form. Congrats @jennysachweh.bsky.social , @becklab.bsky.social and team. Happy I could contribute a little to the story 😊
svenklumpe.bsky.social
Extremely excited for the second version of this workshop at the MPI of Biophysics l, Frankfurt, that will happen 12-20. April 2026. Absolutely amazing lineup of speakers, I am very much looking forward to learning from everyone! Apply here: meetings.embo.org/event/26-in-...
Reposted by Sven Klumpe
thetransmitter.bsky.social
FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.

By @claudia-lopez.bsky.social

www.thetransmitter.org/community/ha...
Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
www.thetransmitter.org
svenklumpe.bsky.social
Behind the paper article by Manel Llado Santaeularia on our manuscript on the in cell structure of a transposable element with @juliusbrennecke.bsky.social. Looking forward to exciting years @viennabiocenter.bsky.social Special thanks @sramundo.bsky.social for making this interaction possible!
svenklumpe.bsky.social
Thanks, excited to be here!
Reposted by Sven Klumpe
deborahbourchis.bsky.social
Exactly two weeks left to submit your abstract to the EMBO Mobile Genome Workshop.
☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th
events.embl.org
⏰ Abstract deadline for 'The mobile genome' is 29 July!

👉 https://s.embl.org/mge25-01-bl

Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍

⭐🧑🏼‍🔬 24 talks + 15 flash talks from posters – don't miss out!

#EMBOMobileGenome
Reposted by Sven Klumpe
vbcscitraining.bsky.social
Learn more about the collaboration possibilities offered at Vienna BioCenter as Victoria Deneke shares her insights as a Postdoc at the Research Institute of Molecular Pathology.

The VIP³ PostDoc Program call is open – apply now! training.vbc.ac.at/post-docs/vi...

#VBCPostDoc
Reposted by Sven Klumpe
dodonova-sveta.bsky.social
We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social!
www.biorxiv.org/content/10.1...
#Chromatin #Asgard #Archaea #cryoEM
svenklumpe.bsky.social
Also always pins down the things one actually doesn’t know regarding an instrument, especially if you dig deeper. Love it, so I’m totally with you!
Reposted by Sven Klumpe
phaips.vd.st
Hey #TeamTomo,
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!

tomoguide.github.io

Follow the thread 1 /🧵
#CryoET #CryoEM 🔬🧪
Welcome to TomoGuide
A step-by-step Cryo-ET guide
tomoguide.github.io
svenklumpe.bsky.social
Cool stuff! Gonna be super useful in teaching, thanks for putting this together Philippe & Florent!
svenklumpe.bsky.social
You should check out drosophila’s bruchpilot 😅 fruit fly has the best names for sure :D