I am proud to share that our work of 4+ years has finally been published. We wondered if there are distinct behaviors that mark sleep in 🪰, where sleep has been defined as prolonged immobility.
🔗 www.science.org/doi/10.1126/...

Bringing some more ExM to #FluorescenceFriday with what appears to be a frustrated cell division in fibroblasts.

More details in Alt-text.

The brain is incredibly densely connected. Human cerebral cortex may have as many as *one trillion* connections.

Most of those cortical connections are recurrent, inside each area. What do they do?

New paper from me in Annual Reviews: 🧪 🧠📈 1/

www.annualreviews.org/content/jour...

🚨Our preprint is online!🚨

www.biorxiv.org/content/10.1...

How do #dopamine neurons perform the key calculations in reinforcement #learning?

Read on to find out more! 🧵

Congrats!🎉🎉🎉

A far-red dopamine sensor unlocks multiplex views of in vivo neuromodulation — a Tools of the Trade article by Yu Zheng

#neuroscience #neuroskyence

www.nature.com/articles/s41...

Finding correlates of the same signal in different brain areas is not evidence against specialisation, it is evidence for interconnection.

When I flush my toilet, the level in the tank and the flow rate in the supply pipe become perfectly correlated. Yet these toilet areas have distinct functions.

super cool. another crack in the genome-centric paradigm,& a great example of Alfonso Martinez Arias’s argument in “The Master Builder." I look forward to anything @philipcball.bsky.social might write about this!

(Disclaimer: all posts represent personal views only)

www.nature.com/articles/s41...

We order ours from Alomone and they have it in stock right now

When neurons change, but behavior doesn’t: Excitability changes driving representational drift

New preprint of work with Christian Machens: www.biorxiv.org/content/10.1...

Check out the latest volume of the Annual Review of Neuroscience 🧠 Take a look at the table of contents arevie.ws/44K8QJZ

1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social
@wellcometrust.bsky.social

Children are incredible language learning machines. But how do they do it? Our latest paper, just published in TICS, synthesizes decades of evidence to propose four components that must be built into any theory of how children learn language. 1/
www.cell.com/trends/cogni... @mpi-nl.bsky.social

🚨 New opinion piece written with Tara Keck

𝘐𝘯𝘵𝘦𝘳𝘢𝘤𝘵𝘪𝘰𝘯𝘴 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 𝘩𝘰𝘮𝘦𝘰𝘴𝘵𝘢𝘵𝘪𝘤 𝘱𝘭𝘢𝘴𝘵𝘪𝘤𝘪𝘵𝘺 𝘢𝘯𝘥 𝘴𝘵𝘢𝘵𝘪𝘴𝘵𝘪𝘤𝘢𝘭 𝘭𝘦𝘢𝘳𝘯𝘪𝘯𝘨: 𝘈 𝘳𝘰𝘭𝘦 𝘧𝘰𝘳 𝘪𝘯𝘩𝘪𝘣𝘪𝘵𝘪𝘰𝘯
rb.gy/m862ik

It's part of a special issue born from an unforgettable science extravaganza hosted by @kitp-ucsb.bsky.social in Santa Barbara🌴🧠
1/🧵

I read about embryonic patch clamp this morning and I'm still thinking about and being amazed by that work🤯

We began a pilot experiment. Lots of sciencey excitement! Then, (pole)catastrophe. Something weaseled into the barn and started killing mice. It kept coming back until it was caught and ID'd: a polecat with a rude demeanor, an appetite for small mammals, and exceptionally bad scientific timing

8/11

The phenomenon you're seeing here is sometimes called a "fire rainbow", which is a misnomer, but beautifully descriptive of a cloud on fire with color.

This is actually the result of light passing through flat, hexagonal plates of ice suspended in clouds.

Let's talk about circumhorizontal arcs.

Why is brainstorming always so much more fun than actually writing up research strategies (I should call it a day since I just spelled "homeostatic" wrong the third time🤦‍♀️

#neuroskyence folks: as my postdoc grant is running out soon, I am looking for new opportunities in systems neuroscience!

Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.

Sharing appreciated, and happy #FluorescenceFriday !

Genetic material shed by tumors can be detected in the bloodstream three years before cancer diagnosis, according to a study led by investigators at Johns Hopkins University.

That study was made possible with federal funding. Now, many studies like this are canceled. hub.jhu.edu/2025/06/04/...

Live a little, comfort a little, cheer thyself a little.

Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...

Feels nice when authors have addressed my comments exactly how I would've done! (Also making the re-review much easier to write haha)

Thank you! Actually a future direction for this project is to collaborate with a computational lab to see how circuits coordinate the control signals for these two mechanisms😉