Apical vs Basolateral secretion of #ExtracellularVesicle of #EndothelialCell
IL-1β modifies miRNA+protein cargoes differentially for Apical vs Basolateral EVs
Apical EV⏬monocyte apoptosis &⏫proinflamm cytokines
Basal EV predicted to impact SMCs
#CircRes 2024
www.ahajournals.org/doi/10.1161/...
IL-1β modifies miRNA+protein cargoes differentially for Apical vs Basolateral EVs
Apical EV⏬monocyte apoptosis &⏫proinflamm cytokines
Basal EV predicted to impact SMCs
#CircRes 2024
www.ahajournals.org/doi/10.1161/...
February 16, 2024 at 8:19 PM
Apical vs Basolateral secretion of #ExtracellularVesicle of #EndothelialCell
IL-1β modifies miRNA+protein cargoes differentially for Apical vs Basolateral EVs
Apical EV⏬monocyte apoptosis &⏫proinflamm cytokines
Basal EV predicted to impact SMCs
#CircRes 2024
www.ahajournals.org/doi/10.1161/...
IL-1β modifies miRNA+protein cargoes differentially for Apical vs Basolateral EVs
Apical EV⏬monocyte apoptosis &⏫proinflamm cytokines
Basal EV predicted to impact SMCs
#CircRes 2024
www.ahajournals.org/doi/10.1161/...
EVs! The morning #worm25 cell bio session kicked off with @inikon.bsky.social talking about proximity labeling to define #cilia #extracellularvesicle subtypes followed by @ahnaskop.bsky.social speaking on the #midbody - a ginormous RNA translating EV🤯 #celegans
July 1, 2025 at 6:33 PM
EVs! The morning #worm25 cell bio session kicked off with @inikon.bsky.social talking about proximity labeling to define #cilia #extracellularvesicle subtypes followed by @ahnaskop.bsky.social speaking on the #midbody - a ginormous RNA translating EV🤯 #celegans
📢 Upcoming mini-symposium: Foundations of EV Therapeutics!
Whether you’re experienced in #ExtracellularVesicle therapy or interested in learning more about this exciting field, this back-to-basics event is not to be missed!
🗓️ April 9th, 1pm AEST
🔗 Register at uni-sydney.zoom.us/meeting/regi...
Whether you’re experienced in #ExtracellularVesicle therapy or interested in learning more about this exciting field, this back-to-basics event is not to be missed!
🗓️ April 9th, 1pm AEST
🔗 Register at uni-sydney.zoom.us/meeting/regi...
March 21, 2025 at 2:41 AM
📢 Upcoming mini-symposium: Foundations of EV Therapeutics!
Whether you’re experienced in #ExtracellularVesicle therapy or interested in learning more about this exciting field, this back-to-basics event is not to be missed!
🗓️ April 9th, 1pm AEST
🔗 Register at uni-sydney.zoom.us/meeting/regi...
Whether you’re experienced in #ExtracellularVesicle therapy or interested in learning more about this exciting field, this back-to-basics event is not to be missed!
🗓️ April 9th, 1pm AEST
🔗 Register at uni-sydney.zoom.us/meeting/regi...
#Extracellularvesicle people: Don't forget, Late Breaking Abstract submission for #ISEV2025 opens 13th of January, until 2nd of February.
🐤 ..and Early Bird registration fees last until 3rd of March
buff.ly/4cYmiKW
🐤 ..and Early Bird registration fees last until 3rd of March
buff.ly/4cYmiKW
International Society for Extracellular Vesicles
buff.ly
January 10, 2025 at 9:27 AM
#Extracellularvesicle people: Don't forget, Late Breaking Abstract submission for #ISEV2025 opens 13th of January, until 2nd of February.
🐤 ..and Early Bird registration fees last until 3rd of March
buff.ly/4cYmiKW
🐤 ..and Early Bird registration fees last until 3rd of March
buff.ly/4cYmiKW
🔬Who is joining our #LiveFromTheLab?
Our #dSTORM training is happening tomorrow and we hope you have your #TrainingKit ready! But wait! Did you know that we also offer new sessions for #ExtracellularVesicle #imaging? The first session is on March 26. 🧬
t.co/IdmYm7Lo0z t.co/ngCMU5qcim
Our #dSTORM training is happening tomorrow and we hope you have your #TrainingKit ready! But wait! Did you know that we also offer new sessions for #ExtracellularVesicle #imaging? The first session is on March 26. 🧬
t.co/IdmYm7Lo0z t.co/ngCMU5qcim
March 19, 2025 at 10:14 AM
🔬Who is joining our #LiveFromTheLab?
Our #dSTORM training is happening tomorrow and we hope you have your #TrainingKit ready! But wait! Did you know that we also offer new sessions for #ExtracellularVesicle #imaging? The first session is on March 26. 🧬
t.co/IdmYm7Lo0z t.co/ngCMU5qcim
Our #dSTORM training is happening tomorrow and we hope you have your #TrainingKit ready! But wait! Did you know that we also offer new sessions for #ExtracellularVesicle #imaging? The first session is on March 26. 🧬
t.co/IdmYm7Lo0z t.co/ngCMU5qcim
Your input matters! Help shape the future of the @gsevorg.bsky.social by sharing what you value and what’s missing. Your feedback will guide us in advancing collaborative German #extracellularvesicle research in 2025. Take 2-3 minutes to complete our survey: docs.google.com/forms/d/1zA8...
GSEV Survey 2025
It's feedback time! Please take 2-3 minutes to fill this survey and take the opportunity to shape GSEV according to your needs. The results will be presented on the next GSEV member's meeting on March...
docs.google.com
January 26, 2025 at 12:09 PM
Your input matters! Help shape the future of the @gsevorg.bsky.social by sharing what you value and what’s missing. Your feedback will guide us in advancing collaborative German #extracellularvesicle research in 2025. Take 2-3 minutes to complete our survey: docs.google.com/forms/d/1zA8...
#Vesiclepedia2024
3533 #ExtracellularVesicle studies
56 organisms
17k mRNAs
5k miRNAs
46k proteins...
microvesicles.org/index.html
Exosomal FGF9 in tumor-endothelial crosstalk👈a paper I missed👍
#NucleicAcidRes 2023
academic.oup.com/nar/advance-...
3533 #ExtracellularVesicle studies
56 organisms
17k mRNAs
5k miRNAs
46k proteins...
microvesicles.org/index.html
Exosomal FGF9 in tumor-endothelial crosstalk👈a paper I missed👍
#NucleicAcidRes 2023
academic.oup.com/nar/advance-...
November 26, 2023 at 7:48 PM
#Vesiclepedia2024
3533 #ExtracellularVesicle studies
56 organisms
17k mRNAs
5k miRNAs
46k proteins...
microvesicles.org/index.html
Exosomal FGF9 in tumor-endothelial crosstalk👈a paper I missed👍
#NucleicAcidRes 2023
academic.oup.com/nar/advance-...
3533 #ExtracellularVesicle studies
56 organisms
17k mRNAs
5k miRNAs
46k proteins...
microvesicles.org/index.html
Exosomal FGF9 in tumor-endothelial crosstalk👈a paper I missed👍
#NucleicAcidRes 2023
academic.oup.com/nar/advance-...
Excited to share that TeLEV is now live! Our preprint introduces a new method to track #extracellularvesicle (EV) proteomes in single cells using advanced techniques. TeLEV reveals insights into an interleukin receptor triad and immune remodeling. Huge thanks to all collaborators! Preprint here:
Single recipient cell tracking of tellurium-labeled extracellular vesicle proteomes (TeLEV) identifies EV-driven immunomodulation
Extracellular vesicles (EVs) mediate tumor-immune cell communication by carrying protein cargo that can immediately modulate signaling and antigen presentation. Yet mapping the uptake of primary EV pr...
www.biorxiv.org
November 4, 2025 at 6:56 AM
Excited to share that TeLEV is now live! Our preprint introduces a new method to track #extracellularvesicle (EV) proteomes in single cells using advanced techniques. TeLEV reveals insights into an interleukin receptor triad and immune remodeling. Huge thanks to all collaborators! Preprint here:
#SpatialTranscriptomics 🐭 #Stroke
Stroke▶️
⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️
⏫remyelination
⏫neurobehavioral performance
Post-stroke benefits of LGALS9-expressing #ExtracellularVesicle
#ScienceTM 2024
www.science.org/doi/10.1126/...
Stroke▶️
⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️
⏫remyelination
⏫neurobehavioral performance
Post-stroke benefits of LGALS9-expressing #ExtracellularVesicle
#ScienceTM 2024
www.science.org/doi/10.1126/...
September 15, 2025 at 7:00 PM
#SpatialTranscriptomics 🐭 #Stroke
Stroke▶️
⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️
⏫remyelination
⏫neurobehavioral performance
Post-stroke benefits of LGALS9-expressing #ExtracellularVesicle
#ScienceTM 2024
www.science.org/doi/10.1126/...
Stroke▶️
⏫Microglia/Macrophage Galectin-1/3/9➡️ Astrocyte/Oligodendrocyte CD44 at peri-infarct zone▶️
⏫remyelination
⏫neurobehavioral performance
Post-stroke benefits of LGALS9-expressing #ExtracellularVesicle
#ScienceTM 2024
www.science.org/doi/10.1126/...
#SmoothMuscleCell-secreted small #ExtracellularVesicle/#Migrasome
⏫by Fibronectin-β1 integrin outside-in signal
⏫its migration velocity + modestly directionality
FN-immobilized sEV can't be uptaken by SMC🤓
Dr. Catherine Shanahan lab bioRxiv 2023
www.biorxiv.org/content/10.1...
⏫by Fibronectin-β1 integrin outside-in signal
⏫its migration velocity + modestly directionality
FN-immobilized sEV can't be uptaken by SMC🤓
Dr. Catherine Shanahan lab bioRxiv 2023
www.biorxiv.org/content/10.1...
October 2, 2023 at 7:20 PM
#SmoothMuscleCell-secreted small #ExtracellularVesicle/#Migrasome
⏫by Fibronectin-β1 integrin outside-in signal
⏫its migration velocity + modestly directionality
FN-immobilized sEV can't be uptaken by SMC🤓
Dr. Catherine Shanahan lab bioRxiv 2023
www.biorxiv.org/content/10.1...
⏫by Fibronectin-β1 integrin outside-in signal
⏫its migration velocity + modestly directionality
FN-immobilized sEV can't be uptaken by SMC🤓
Dr. Catherine Shanahan lab bioRxiv 2023
www.biorxiv.org/content/10.1...
Liver-to-Aorta communication😎
#Atheroasclerosis #MAFLD #MedialArterialCalcification
Steatotic Liver-derived #ExtracellularVesicle
⏫atherosclerotic lesion +calcification
⏫MAFLD-associated arterial calcification
⏫Osteogenesis of #SmoothMuscleCell
#AdvSci 2024
onlinelibrary.wiley.com/doi/10.1002/...
#Atheroasclerosis #MAFLD #MedialArterialCalcification
Steatotic Liver-derived #ExtracellularVesicle
⏫atherosclerotic lesion +calcification
⏫MAFLD-associated arterial calcification
⏫Osteogenesis of #SmoothMuscleCell
#AdvSci 2024
onlinelibrary.wiley.com/doi/10.1002/...
January 1, 2025 at 4:13 PM
Liver-to-Aorta communication😎
#Atheroasclerosis #MAFLD #MedialArterialCalcification
Steatotic Liver-derived #ExtracellularVesicle
⏫atherosclerotic lesion +calcification
⏫MAFLD-associated arterial calcification
⏫Osteogenesis of #SmoothMuscleCell
#AdvSci 2024
onlinelibrary.wiley.com/doi/10.1002/...
#Atheroasclerosis #MAFLD #MedialArterialCalcification
Steatotic Liver-derived #ExtracellularVesicle
⏫atherosclerotic lesion +calcification
⏫MAFLD-associated arterial calcification
⏫Osteogenesis of #SmoothMuscleCell
#AdvSci 2024
onlinelibrary.wiley.com/doi/10.1002/...
OsteoImmune Surveillance
⏬in #Aging
⏫by #Sirt6
Sirt6 in apoptotic osteoblast⏬CD47 (Don't eat me signal)+release of apoptotic #ExtracellularVesicle to attract Mφ
Sirt6 in Mφ⏫SIRPα+#Efferocytosis ability
J Cheng, H Jiang labs #AdvSci 2023
onlinelibrary.wiley.com/doi/10.1002/...
⏬in #Aging
⏫by #Sirt6
Sirt6 in apoptotic osteoblast⏬CD47 (Don't eat me signal)+release of apoptotic #ExtracellularVesicle to attract Mφ
Sirt6 in Mφ⏫SIRPα+#Efferocytosis ability
J Cheng, H Jiang labs #AdvSci 2023
onlinelibrary.wiley.com/doi/10.1002/...
November 23, 2023 at 7:42 PM
OsteoImmune Surveillance
⏬in #Aging
⏫by #Sirt6
Sirt6 in apoptotic osteoblast⏬CD47 (Don't eat me signal)+release of apoptotic #ExtracellularVesicle to attract Mφ
Sirt6 in Mφ⏫SIRPα+#Efferocytosis ability
J Cheng, H Jiang labs #AdvSci 2023
onlinelibrary.wiley.com/doi/10.1002/...
⏬in #Aging
⏫by #Sirt6
Sirt6 in apoptotic osteoblast⏬CD47 (Don't eat me signal)+release of apoptotic #ExtracellularVesicle to attract Mφ
Sirt6 in Mφ⏫SIRPα+#Efferocytosis ability
J Cheng, H Jiang labs #AdvSci 2023
onlinelibrary.wiley.com/doi/10.1002/...
Here’s an #extracellularvesicle start pack #research #cancer #intercellular #interactions #cellbiology #liquidbiopsy
November 17, 2024 at 5:48 PM
Here’s an #extracellularvesicle start pack #research #cancer #intercellular #interactions #cellbiology #liquidbiopsy
This study shows that #Peritoneal #AdiposeDerivedStemCells orchestrate #disease progression and #Metastasis in #OvarianCancer through #ExtracellularVesicle-mediated, long-range modulation of #EGFR and #NFκB signaling pathways. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
#OpenAccess: www.sciencedirect.com/science/arti...
November 14, 2025 at 1:41 AM
This study shows that #Peritoneal #AdiposeDerivedStemCells orchestrate #disease progression and #Metastasis in #OvarianCancer through #ExtracellularVesicle-mediated, long-range modulation of #EGFR and #NFκB signaling pathways. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
#OpenAccess: www.sciencedirect.com/science/arti...
A #bioengineered #ExtracellularVesicle therapy with #PDL1 and #miR27a3p reprograms T‑cell immunity in #InflammatoryBowelDisease by suppressing Th17 #bioenergetics, expanding #Tregs, reducing inflammation, and preserving gut epithelial integrity.
#STTT: doi.org/10.1038/s413...
#STTT: doi.org/10.1038/s413...
Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease
doi.org
December 30, 2025 at 8:00 PM
A #bioengineered #ExtracellularVesicle therapy with #PDL1 and #miR27a3p reprograms T‑cell immunity in #InflammatoryBowelDisease by suppressing Th17 #bioenergetics, expanding #Tregs, reducing inflammation, and preserving gut epithelial integrity.
#STTT: doi.org/10.1038/s413...
#STTT: doi.org/10.1038/s413...
Presentation EV 2025 - IT Biologie cellulaire, reproduction, développement et évolution
itbcde.inserm.fr
February 7, 2025 at 9:53 PM
📢Publication Alert🌶️! Researchers from #LJMU used #Mag_Net_SAX to identify potential #ExtracellularVesicle plasma proteome markers for professional #RugbyPlayers, identifying protein risk markers with potential for monitoring and guiding treatment! onlinelibrary.wiley.com/doi/10.1002/...
December 2, 2025 at 10:04 AM
📢Publication Alert🌶️! Researchers from #LJMU used #Mag_Net_SAX to identify potential #ExtracellularVesicle plasma proteome markers for professional #RugbyPlayers, identifying protein risk markers with potential for monitoring and guiding treatment! onlinelibrary.wiley.com/doi/10.1002/...
This week #JournalClub @labsoap.bsky.social #gasdermin #pyroptosis #extracellularvesicle #DNAPaint @cellpress.bsky.social www.cell.com/cell/abstrac...
Transplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cells
Expanding the consequences of pyroptosis, this study reveals that GSDMD pore-laden
pyroptotic EVs transplant GSDMD pores on neighboring cell surfaces and propagate cell
death to bystander cells.
www.cell.com
January 13, 2025 at 5:48 PM
In recent years, we have developed tools to gain deeper insights into #extracellularvesicle immune cell interactions in B-cell malignancies. We have learned a lot and want to share our perspective: doi.org/10.1002/1873...
FEBS Press
Click on the article title to read more.
doi.org
July 4, 2025 at 5:45 PM
In recent years, we have developed tools to gain deeper insights into #extracellularvesicle immune cell interactions in B-cell malignancies. We have learned a lot and want to share our perspective: doi.org/10.1002/1873...
#Research
MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors doi.org/10.1186/s435...
#MITF #ChIPseq #Autophagy #ExtracellularVesicle #GIST
MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors doi.org/10.1186/s435...
#MITF #ChIPseq #Autophagy #ExtracellularVesicle #GIST
MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors - Molecular Biomedicine
The role of Microphthalmia-associated Transcription Factor (MITF) in gastrointestinal stromal tumors (GISTs) remains unclear, although previous studies suggest it contributes to tumor growth regulatio...
doi.org
November 7, 2025 at 8:41 AM
#Research
MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors doi.org/10.1186/s435...
#MITF #ChIPseq #Autophagy #ExtracellularVesicle #GIST
MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors doi.org/10.1186/s435...
#MITF #ChIPseq #Autophagy #ExtracellularVesicle #GIST
Check out the brand new @gsevorg.bsky.social
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
January 24, 2025 at 6:32 PM
Check out the brand new @gsevorg.bsky.social
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
January 2025 Newsletter! Explore EV research updates, upcoming events in 2025 (IGLD/GSEV Spring Meeting, GSEV Autumn Meeting, new calls for MOVE scholarships), and more. Join us in advancing #extracellularvesicle research.
➡️http://gsev.org
#ExtraCellularMatrix #ArterialAging Sox9
#SmoothMuscleCell Sox9➡️#ExtracellularVesicle (PLOD3)➡️ECM Stiffness➡️SMC #Senescence & likely #ArterialStiffening
Senescent #SmoothMuscleCell, seeded on ECM deposited by Sox9-KD SMCs, can proliferate again!
#CircRes 2024
www.ahajournals.org/doi/abs/10.1...
#SmoothMuscleCell Sox9➡️#ExtracellularVesicle (PLOD3)➡️ECM Stiffness➡️SMC #Senescence & likely #ArterialStiffening
Senescent #SmoothMuscleCell, seeded on ECM deposited by Sox9-KD SMCs, can proliferate again!
#CircRes 2024
www.ahajournals.org/doi/abs/10.1...
April 2, 2024 at 7:35 PM
#ExtraCellularMatrix #ArterialAging Sox9
#SmoothMuscleCell Sox9➡️#ExtracellularVesicle (PLOD3)➡️ECM Stiffness➡️SMC #Senescence & likely #ArterialStiffening
Senescent #SmoothMuscleCell, seeded on ECM deposited by Sox9-KD SMCs, can proliferate again!
#CircRes 2024
www.ahajournals.org/doi/abs/10.1...
#SmoothMuscleCell Sox9➡️#ExtracellularVesicle (PLOD3)➡️ECM Stiffness➡️SMC #Senescence & likely #ArterialStiffening
Senescent #SmoothMuscleCell, seeded on ECM deposited by Sox9-KD SMCs, can proliferate again!
#CircRes 2024
www.ahajournals.org/doi/abs/10.1...
Our EV #webinar is now available on demand 🎥
Catch the session to see how AI-driven automation is transforming #extracellularvesicle characterization, and be among the first to preview ONI's Axis Tools 2.0.
Watch it here: zurl.co/Ca5Fd
#EVs #evresearch #automation
Catch the session to see how AI-driven automation is transforming #extracellularvesicle characterization, and be among the first to preview ONI's Axis Tools 2.0.
Watch it here: zurl.co/Ca5Fd
#EVs #evresearch #automation
December 10, 2025 at 7:24 AM
Our EV #webinar is now available on demand 🎥
Catch the session to see how AI-driven automation is transforming #extracellularvesicle characterization, and be among the first to preview ONI's Axis Tools 2.0.
Watch it here: zurl.co/Ca5Fd
#EVs #evresearch #automation
Catch the session to see how AI-driven automation is transforming #extracellularvesicle characterization, and be among the first to preview ONI's Axis Tools 2.0.
Watch it here: zurl.co/Ca5Fd
#EVs #evresearch #automation
Here is a starter pack of #extracellularvesicle scientist working in the field of #cancer:
go.bsky.app/Cjt6Ks3
Hope you will find it useful.
go.bsky.app/Cjt6Ks3
Hope you will find it useful.
November 23, 2024 at 1:56 PM
Here is a starter pack of #extracellularvesicle scientist working in the field of #cancer:
go.bsky.app/Cjt6Ks3
Hope you will find it useful.
go.bsky.app/Cjt6Ks3
Hope you will find it useful.
🌿 The #NutriEV team participated at the 3rd #MOVESymposium2025 in Tartu to share advances in #ExtracellularVesicle research.
Prof. Seppo Vainio presented work on excreted EVs as diagnostic tools, and Dr Gabriella Pocsfalvi highlighted plant-derived nanovesicles
🔗 Read more: t.ly/DT2F5
#Nutrition
Prof. Seppo Vainio presented work on excreted EVs as diagnostic tools, and Dr Gabriella Pocsfalvi highlighted plant-derived nanovesicles
🔗 Read more: t.ly/DT2F5
#Nutrition
November 10, 2025 at 9:57 AM
🌿 The #NutriEV team participated at the 3rd #MOVESymposium2025 in Tartu to share advances in #ExtracellularVesicle research.
Prof. Seppo Vainio presented work on excreted EVs as diagnostic tools, and Dr Gabriella Pocsfalvi highlighted plant-derived nanovesicles
🔗 Read more: t.ly/DT2F5
#Nutrition
Prof. Seppo Vainio presented work on excreted EVs as diagnostic tools, and Dr Gabriella Pocsfalvi highlighted plant-derived nanovesicles
🔗 Read more: t.ly/DT2F5
#Nutrition