Add DNA methylation, mitochondrial dysfunction, accelerated aging and oncogenicity, its persistence and latency, and its astounding capacity of reinfecting people (showing the impossibility of immunity beyond the delayed period of infection or vaccination (months, just months).
Sars2 is a beast.
Sars2 is a beast.
October 23, 2025 at 8:07 PM
Add DNA methylation, mitochondrial dysfunction, accelerated aging and oncogenicity, its persistence and latency, and its astounding capacity of reinfecting people (showing the impossibility of immunity beyond the delayed period of infection or vaccination (months, just months).
Sars2 is a beast.
Sars2 is a beast.
Anti-vax politicians in Montana introduced a bill HB 371 to ban mRNA and DNA vaccines. 🙄
Contrary to their false claims, mRNA COVID vaccines are safe, well-studied, don’t shed, don’t “integrate into the human genome”, and are not contaminated.
Contrary to their false claims, mRNA COVID vaccines are safe, well-studied, don’t shed, don’t “integrate into the human genome”, and are not contaminated.
February 7, 2025 at 3:05 AM
Anti-vax politicians in Montana introduced a bill HB 371 to ban mRNA and DNA vaccines. 🙄
Contrary to their false claims, mRNA COVID vaccines are safe, well-studied, don’t shed, don’t “integrate into the human genome”, and are not contaminated.
Contrary to their false claims, mRNA COVID vaccines are safe, well-studied, don’t shed, don’t “integrate into the human genome”, and are not contaminated.
Mardis - MCI - challenges. Now 200 tumors/month. Tumor/normal exome is the hardest to sign out. Have to evaluate data from your own study and outside resources. Variant Categorizer (VarCat) Tool. Reduce manual searching using VICC MetaKB service for somatic - using Oncogenicity. #AACR2025
April 27, 2025 at 9:42 PM
Mardis - MCI - challenges. Now 200 tumors/month. Tumor/normal exome is the hardest to sign out. Have to evaluate data from your own study and outside resources. Variant Categorizer (VarCat) Tool. Reduce manual searching using VICC MetaKB service for somatic - using Oncogenicity. #AACR2025
ok. now we have a low oncogenicity protocol developed. how to put it into a patient now?
June 11, 2025 at 4:54 AM
ok. now we have a low oncogenicity protocol developed. how to put it into a patient now?
Tyrosine aspartic acid repeat and high mobility group box DNA binding protein 1 is somehow involved in DNA repair, making it a candidate for embryonic enrichment. Frequent attempts to demonstrate its potential for oncogenicity make a case against the probative value of the concept. #proteomics
September 2, 2025 at 12:45 PM
Tyrosine aspartic acid repeat and high mobility group box DNA binding protein 1 is somehow involved in DNA repair, making it a candidate for embryonic enrichment. Frequent attempts to demonstrate its potential for oncogenicity make a case against the probative value of the concept. #proteomics
Unraveling the network signatures of oncogenicity in virus-human protein-protein interactions https://www.biorxiv.org/content/10.1101/2025.01.14.632978v1
January 15, 2025 at 6:42 PM
Unraveling the network signatures of oncogenicity in virus-human protein-protein interactions https://www.biorxiv.org/content/10.1101/2025.01.14.632978v1
A unified model for Duchenne muscular dystrophy gene involvement in cancer: context-dependent tumour suppression and oncogenicity
🔦 buff.ly/lBnkwMP
🥼 @drleemachado.bsky.social
#CancerResearch #DuchenneMuscularDystrophy
🔦 buff.ly/lBnkwMP
🥼 @drleemachado.bsky.social
#CancerResearch #DuchenneMuscularDystrophy
September 25, 2025 at 9:15 AM
A unified model for Duchenne muscular dystrophy gene involvement in cancer: context-dependent tumour suppression and oncogenicity
🔦 buff.ly/lBnkwMP
🥼 @drleemachado.bsky.social
#CancerResearch #DuchenneMuscularDystrophy
🔦 buff.ly/lBnkwMP
🥼 @drleemachado.bsky.social
#CancerResearch #DuchenneMuscularDystrophy
A preclinical study interrogates how a cytokine cocktail can invigorate cancer-fighting natural killer cells, new experiments reveal how the oncogenicity of RAS is a family affair, and more in the new issue of #ScienceSignaling. https://scim.ag/4n2QPwW
September 16, 2025 at 9:00 PM
A preclinical study interrogates how a cytokine cocktail can invigorate cancer-fighting natural killer cells, new experiments reveal how the oncogenicity of RAS is a family affair, and more in the new issue of #ScienceSignaling. https://scim.ag/4n2QPwW
->Hear from Karen Tsuchiya from Nationwide Children's Hospital as they share recommendations for gene fusion oncogenicity classification in clinical contexts. 2/7 #CGCAnnual2025
August 5, 2025 at 7:04 PM
->Hear from Karen Tsuchiya from Nationwide Children's Hospital as they share recommendations for gene fusion oncogenicity classification in clinical contexts. 2/7 #CGCAnnual2025
Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing https://www.biorxiv.org/content/10.1101/2024.02.21.581397v1
Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing https://www.biorxiv.org/content/10.1101/2024.02.21.581397v1
Effective therapies for retroperitoneal (RP) dedifferentiated liposarcoma (DDLPS) remain unavailable
www.biorxiv.org
February 23, 2024 at 4:21 AM
Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing https://www.biorxiv.org/content/10.1101/2024.02.21.581397v1
I agree with most of this. But I think that there is a long way between peer-reviewed articles pointing out the possibility of oncogenicity and tin-foil-hat conspiracy theory.
December 3, 2024 at 12:11 PM
I agree with most of this. But I think that there is a long way between peer-reviewed articles pointing out the possibility of oncogenicity and tin-foil-hat conspiracy theory.
RRID:Addgene_8454, was just reported to be used in "PAR2 Serves an Indispensable Role in Controlling PAR4 Oncogenicity: The β-Catenin–p53 Axis". We appreciate the author's support of reproducibility. #methodsmatter #methodsmatter
doi.org
April 12, 2025 at 7:01 AM
RRID:Addgene_8454, was just reported to be used in "PAR2 Serves an Indispensable Role in Controlling PAR4 Oncogenicity: The β-Catenin–p53 Axis". We appreciate the author's support of reproducibility. #methodsmatter #methodsmatter
Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing https://www.biorxiv.org/content/10.1101/2024.02.21.581397v1
Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing https://www.biorxiv.org/content/10.1101/2024.02.21.581397v1
Effective therapies for retroperitoneal (RP) dedifferentiated liposarcoma (DDLPS) remain unavailable
www.biorxiv.org
February 23, 2024 at 4:21 AM
Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing https://www.biorxiv.org/content/10.1101/2024.02.21.581397v1
-> Hear from Mark Evans from Caris Life Sciences, on new guidelines to classify oncogenicity in BCR::ABL1-like B-ALL, improving diagnostic precision. 4/5 #CGCAnnual2025
August 3, 2025 at 10:15 PM
-> Hear from Mark Evans from Caris Life Sciences, on new guidelines to classify oncogenicity in BCR::ABL1-like B-ALL, improving diagnostic precision. 4/5 #CGCAnnual2025
A preclinical study interrogates how a cytokine cocktail can invigorate cancer-fighting natural killer cells, new experiments reveal how the oncogenicity of RAS is a family affair, and more in the new issue of #ScienceSignaling.
scim.ag/3IqMdll
scim.ag/3IqMdll
Contents | Science Signaling 18, 904
scim.ag
September 17, 2025 at 2:25 PM
A preclinical study interrogates how a cytokine cocktail can invigorate cancer-fighting natural killer cells, new experiments reveal how the oncogenicity of RAS is a family affair, and more in the new issue of #ScienceSignaling.
scim.ag/3IqMdll
scim.ag/3IqMdll
Summarizing the #Epidemiology of virus-related tumors, infectivity, and #Oncogenicity mechanisms of #OncogenicViruses, with a discussion on the current therapeutic strategies for virus-related tumors.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
November 6, 2025 at 12:49 PM
Summarizing the #Epidemiology of virus-related tumors, infectivity, and #Oncogenicity mechanisms of #OncogenicViruses, with a discussion on the current therapeutic strategies for virus-related tumors.
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
...to hiding of factors as oncogenicity, neurovirulence, dementia catalyst, persistence, inmuno-depletion, and the biological processes that are harming the human body, to the deliberate negligence of implementing the most basic measures. Everywhere around us was conspiring to obscure the pandemic.
April 18, 2025 at 7:30 AM
...to hiding of factors as oncogenicity, neurovirulence, dementia catalyst, persistence, inmuno-depletion, and the biological processes that are harming the human body, to the deliberate negligence of implementing the most basic measures. Everywhere around us was conspiring to obscure the pandemic.
Unraveling the network signatures of oncogenicity in virus-human protein-protein interactions https://www.biorxiv.org/content/10.1101/2025.01.14.632978v1
January 15, 2025 at 6:42 PM
Unraveling the network signatures of oncogenicity in virus-human protein-protein interactions https://www.biorxiv.org/content/10.1101/2025.01.14.632978v1
Mark your calendar for our next expert-led webinar on HPV and the microbiome.
Learn how abnormal microbiomes can impact HPV oncogenicity, and what evidence-based strategies can help reduce the risk.
📅 Wed, 4 June
Register ➡️ bit.ly/4mi22d2
#HPV #Webinar #CancerResearch
Learn how abnormal microbiomes can impact HPV oncogenicity, and what evidence-based strategies can help reduce the risk.
📅 Wed, 4 June
Register ➡️ bit.ly/4mi22d2
#HPV #Webinar #CancerResearch
May 15, 2025 at 11:33 AM
Mark your calendar for our next expert-led webinar on HPV and the microbiome.
Learn how abnormal microbiomes can impact HPV oncogenicity, and what evidence-based strategies can help reduce the risk.
📅 Wed, 4 June
Register ➡️ bit.ly/4mi22d2
#HPV #Webinar #CancerResearch
Learn how abnormal microbiomes can impact HPV oncogenicity, and what evidence-based strategies can help reduce the risk.
📅 Wed, 4 June
Register ➡️ bit.ly/4mi22d2
#HPV #Webinar #CancerResearch
Impurities — one of the biggest drawbacks of using biological cell lines to make therapeutic proteins.
With the risk of immunogenicity and even oncogenicity, it's important to know about any host cell proteins or host cell DNA and get it out.
With the risk of immunogenicity and even oncogenicity, it's important to know about any host cell proteins or host cell DNA and get it out.
USP Chapter Covers Residual DNA Testing Practices For CHO And E. coli
<p>Industry widely uses qPCR to measure residual DNA; however, the technique lacked a standard. USP's General Chapter <509> aims to remedy that.</p>
www.bioprocessonline.com
December 4, 2024 at 3:23 PM
Impurities — one of the biggest drawbacks of using biological cell lines to make therapeutic proteins.
With the risk of immunogenicity and even oncogenicity, it's important to know about any host cell proteins or host cell DNA and get it out.
With the risk of immunogenicity and even oncogenicity, it's important to know about any host cell proteins or host cell DNA and get it out.
Meet the experts who will delve into the crucial link between the microbiome and #HPV infection.
Join them on June 4 to discover how an imbalanced microbiome can enhance HPV oncogenicity, hear about the latest evidence-based strategies to help reduce the risk and earn CME credits.
🔗 bit.ly/4mi22d2
Join them on June 4 to discover how an imbalanced microbiome can enhance HPV oncogenicity, hear about the latest evidence-based strategies to help reduce the risk and earn CME credits.
🔗 bit.ly/4mi22d2
May 28, 2025 at 9:12 AM
Meet the experts who will delve into the crucial link between the microbiome and #HPV infection.
Join them on June 4 to discover how an imbalanced microbiome can enhance HPV oncogenicity, hear about the latest evidence-based strategies to help reduce the risk and earn CME credits.
🔗 bit.ly/4mi22d2
Join them on June 4 to discover how an imbalanced microbiome can enhance HPV oncogenicity, hear about the latest evidence-based strategies to help reduce the risk and earn CME credits.
🔗 bit.ly/4mi22d2
GR: Oncogenicity: gene function, functional domains, hotspots, functional data. Clinical significance: pathology/WHO classifications (diagnostic markers), prognostic associations (prognostic markers), treatment data. #ACMGmtg24
March 15, 2024 at 8:30 PM
GR: Oncogenicity: gene function, functional domains, hotspots, functional data. Clinical significance: pathology/WHO classifications (diagnostic markers), prognostic associations (prognostic markers), treatment data. #ACMGmtg24
So many young people are dying of never-before-seen levels of aggressive cancers amidst constant reinfections of Covid. No governing body is telling the public the dangers of the oncogenicity & how it's linked
Please mask with N95 or better respirator to limit the infections you get💔
Please mask with N95 or better respirator to limit the infections you get💔
December 23, 2024 at 6:17 PM
So many young people are dying of never-before-seen levels of aggressive cancers amidst constant reinfections of Covid. No governing body is telling the public the dangers of the oncogenicity & how it's linked
Please mask with N95 or better respirator to limit the infections you get💔
Please mask with N95 or better respirator to limit the infections you get💔