Timmer, Kumar, G\"otze, Saalfrank, De Sio, Lienau: Nonadiabatic couplings drive ultrafast, mode-selective intramolecular vibrational energy redistribution in flavins https://arxiv.org/abs/2601.10273 https://arxiv.org/pdf/2601.10273 https://arxiv.org/html/2601.10273
January 16, 2026 at 6:47 AM
Timmer, Kumar, G\"otze, Saalfrank, De Sio, Lienau: Nonadiabatic couplings drive ultrafast, mode-selective intramolecular vibrational energy redistribution in flavins https://arxiv.org/abs/2601.10273 https://arxiv.org/pdf/2601.10273 https://arxiv.org/html/2601.10273
6/ These transfers happen quickly and create short-lived intermediate states that are sensitive to the local molecular environment. Flavins are known to participate in reactions that involve rapid electron motion, which is one reason GR is interesting to examine through a quantum lens.
December 18, 2025 at 3:48 AM
6/ These transfers happen quickly and create short-lived intermediate states that are sensitive to the local molecular environment. Flavins are known to participate in reactions that involve rapid electron motion, which is one reason GR is interesting to examine through a quantum lens.
Some human endogenous pigments that interfere with fluorescence-based imaging:
- lipofuscin (脂褐质),
- nicotinamide adenine dinucleotide (NAD, 烟酰胺腺嘌呤二核苷酸),
- flavins (黄素),
- hemoglobin (血红蛋白) and its breakdown products,
- bisretinoids (双视黄醇类)
pubmed.ncbi.nlm.nih.gov/40961137/
- lipofuscin (脂褐质),
- nicotinamide adenine dinucleotide (NAD, 烟酰胺腺嘌呤二核苷酸),
- flavins (黄素),
- hemoglobin (血红蛋白) and its breakdown products,
- bisretinoids (双视黄醇类)
pubmed.ncbi.nlm.nih.gov/40961137/
An open-source photobleacher for fluorescence imaging of large pigment-rich tissues - PubMed
Fluorescence imaging enables visualization of the specific molecules of interest with high contrast, and the use of multiple fluorophores in a single tissue sample allows visualization of complex relationships between biological molecules, cell types, and anatomy. The utility of fluorescence imaging …
pubmed.ncbi.nlm.nih.gov
December 3, 2025 at 7:36 AM
Some human endogenous pigments that interfere with fluorescence-based imaging:
- lipofuscin (脂褐质),
- nicotinamide adenine dinucleotide (NAD, 烟酰胺腺嘌呤二核苷酸),
- flavins (黄素),
- hemoglobin (血红蛋白) and its breakdown products,
- bisretinoids (双视黄醇类)
pubmed.ncbi.nlm.nih.gov/40961137/
- lipofuscin (脂褐质),
- nicotinamide adenine dinucleotide (NAD, 烟酰胺腺嘌呤二核苷酸),
- flavins (黄素),
- hemoglobin (血红蛋白) and its breakdown products,
- bisretinoids (双视黄醇类)
pubmed.ncbi.nlm.nih.gov/40961137/
Our latest work on bioengineering electricity production from microbes comes to life 🦠⚡️We engineer E. coli to secret flavins -- electron shuttles that transfer charge to electrodes remotely. Congratulations to Mohammed Mouhib, @m-reggente.bsky.social and team! @microbesinfo.bsky.social
New paper out: a method to further bioengineer electroactive E. coli to enhance mediated extracellular electron transfer. Led by Mohammed Mouhib, with key help from Hanxuan Wang and Charlotte Roullier and the steady support from @ardemisprime.bsky.social
Flavin Biosynthesis Enhances Extracellular Electron Transfer in Bioengineered Escherichia coli
Microbial electronics are promising for energy, sensing, environmental, and synthesis applications. E. coli are engineered with extracellular electron transfer (EET) pathways from a microbe that natu...
advanced.onlinelibrary.wiley.com
November 26, 2025 at 6:38 PM
Our latest work on bioengineering electricity production from microbes comes to life 🦠⚡️We engineer E. coli to secret flavins -- electron shuttles that transfer charge to electrodes remotely. Congratulations to Mohammed Mouhib, @m-reggente.bsky.social and team! @microbesinfo.bsky.social
New paper at @chemcomm.rsc.org with @lsalassa.bsky.social and I14 at @diamondlightsource.bsky.social
X-ray spectromicroscopy shows that conjugating flavins to PtIV prodrugs improve greatly activation efficiency, even at much lower irradiation dose!
@dipcehu.bsky.social
doi.org/10.1039/D5CC...
X-ray spectromicroscopy shows that conjugating flavins to PtIV prodrugs improve greatly activation efficiency, even at much lower irradiation dose!
@dipcehu.bsky.social
doi.org/10.1039/D5CC...
October 27, 2025 at 9:43 AM
New paper at @chemcomm.rsc.org with @lsalassa.bsky.social and I14 at @diamondlightsource.bsky.social
X-ray spectromicroscopy shows that conjugating flavins to PtIV prodrugs improve greatly activation efficiency, even at much lower irradiation dose!
@dipcehu.bsky.social
doi.org/10.1039/D5CC...
X-ray spectromicroscopy shows that conjugating flavins to PtIV prodrugs improve greatly activation efficiency, even at much lower irradiation dose!
@dipcehu.bsky.social
doi.org/10.1039/D5CC...
Our health secretary recommends a stiff shot of heroin to get into the flow. Or maybe ripping into the internal organs of your neighbor's dog, for the vital flavins depriving America's youth.
Or not, because he's stupid. The only heroin I need is my heroine "Gina Biggs".
Or not, because he's stupid. The only heroin I need is my heroine "Gina Biggs".
September 17, 2025 at 11:45 PM
Our health secretary recommends a stiff shot of heroin to get into the flow. Or maybe ripping into the internal organs of your neighbor's dog, for the vital flavins depriving America's youth.
Or not, because he's stupid. The only heroin I need is my heroine "Gina Biggs".
Or not, because he's stupid. The only heroin I need is my heroine "Gina Biggs".
A study of residents of Ferrara, Italy, where malaria was once endemic, and Huye, Rwanda, where it still is endemic, found a small proportion of people genetically deficient in flavins—a deficiency that protects red blood cells from malaria. In PNAS: www.pnas.org/doi/10.1073/...
September 17, 2025 at 7:35 PM
A study of residents of Ferrara, Italy, where malaria was once endemic, and Huye, Rwanda, where it still is endemic, found a small proportion of people genetically deficient in flavins—a deficiency that protects red blood cells from malaria. In PNAS: www.pnas.org/doi/10.1073/...
New pre-print! Flavins are essential cofactors in biology, acting as both one- and two-electron redox cofactors, yet how the protein scaffold tunes redox chemistry has been difficult to discern. Here, we examine how the N5 environment controls flavin potentials. (1/n) www.biorxiv.org/content/10.1...
Measurement and Control of Crossed Potentials in a Flavoprotein
Flavoproteins are versatile redox-active biomolecules enabling a multitude of metabolic processes. Their versatility stems from the tunability of the flavin cofactor′s one- and two-electron reduction ...
www.biorxiv.org
September 15, 2025 at 6:20 PM
New pre-print! Flavins are essential cofactors in biology, acting as both one- and two-electron redox cofactors, yet how the protein scaffold tunes redox chemistry has been difficult to discern. Here, we examine how the N5 environment controls flavin potentials. (1/n) www.biorxiv.org/content/10.1...
Flavins are light sensitive and can form stable radicals, which may allow them to be affected by magnetic fields under certain conditions. Scientists think this could be due to something called the radical pair mechanism, a possible way that magnetism affects living things at the quantum level.
August 9, 2025 at 6:35 PM
Flavins are light sensitive and can form stable radicals, which may allow them to be affected by magnetic fields under certain conditions. Scientists think this could be due to something called the radical pair mechanism, a possible way that magnetism affects living things at the quantum level.
AKA: he’s creating the instructions for bacteria to start producing proteins that QBI wants to study.
These proteins, called flavoproteins, bind a small molecule called a flavins, small molecules derived from riboflavin (vitamin B2).
These proteins, called flavoproteins, bind a small molecule called a flavins, small molecules derived from riboflavin (vitamin B2).
August 9, 2025 at 6:35 PM
AKA: he’s creating the instructions for bacteria to start producing proteins that QBI wants to study.
These proteins, called flavoproteins, bind a small molecule called a flavins, small molecules derived from riboflavin (vitamin B2).
These proteins, called flavoproteins, bind a small molecule called a flavins, small molecules derived from riboflavin (vitamin B2).
I've been thinking a lot about flavins and interested to hear @chemsky.bsky.social 's opinions here. Ingraham used a thermodynamic model and potentiometric titrations to estimate E1 (OX/SQ), E2 (SQ/HQ) and Em (OX/HQ). Em was -200 mV , and dE was 64 mV. (1/n)
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
A potentiometric study of the flavin semiquinone equilibrium
Potentiometric studies of the riboflavin and flavin mononucleotide (FMN) equilibria with reduced and semiquinone species have been performed by the cl…
www.sciencedirect.com
July 3, 2025 at 5:42 PM
I've been thinking a lot about flavins and interested to hear @chemsky.bsky.social 's opinions here. Ingraham used a thermodynamic model and potentiometric titrations to estimate E1 (OX/SQ), E2 (SQ/HQ) and Em (OX/HQ). Em was -200 mV , and dE was 64 mV. (1/n)
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
🧪 Work from Prof. Radek Cibulka’s team featured on the cover of Chemical Science!
In collaboration with Adam Mickiewicz University, the team developed a new photocatalytic reduction system based on deprotonated flavins – derivatives of vitamin B2.
In collaboration with Adam Mickiewicz University, the team developed a new photocatalytic reduction system based on deprotonated flavins – derivatives of vitamin B2.
June 26, 2025 at 11:16 AM
🧪 Work from Prof. Radek Cibulka’s team featured on the cover of Chemical Science!
In collaboration with Adam Mickiewicz University, the team developed a new photocatalytic reduction system based on deprotonated flavins – derivatives of vitamin B2.
In collaboration with Adam Mickiewicz University, the team developed a new photocatalytic reduction system based on deprotonated flavins – derivatives of vitamin B2.
Congratulations to Dr. Marika David! Marika David successfully defended her PhD thesis today. At her seminar earlier today we learned about her work in the Culotta Lab on “Iron and Flavins: Essential Nutrients in the Fungal Pathogen Candida albicans”
June 24, 2025 at 8:29 PM
Congratulations to Dr. Marika David! Marika David successfully defended her PhD thesis today. At her seminar earlier today we learned about her work in the Culotta Lab on “Iron and Flavins: Essential Nutrients in the Fungal Pathogen Candida albicans”
Upcoming PhD defense seminar! Marika David of the Culotta Lab will present “Iron and Flavins: Essential Nutrients in the Fungal Pathogen Candida albicans”
🗓️Tuesday, June 24
⏰2 p.m. ET
📍 Becton Dickinson Hall (W1020)
🔗Open to the BMB community via Zoom - DM for link by Friday June 20
🗓️Tuesday, June 24
⏰2 p.m. ET
📍 Becton Dickinson Hall (W1020)
🔗Open to the BMB community via Zoom - DM for link by Friday June 20
June 11, 2025 at 6:36 PM
Upcoming PhD defense seminar! Marika David of the Culotta Lab will present “Iron and Flavins: Essential Nutrients in the Fungal Pathogen Candida albicans”
🗓️Tuesday, June 24
⏰2 p.m. ET
📍 Becton Dickinson Hall (W1020)
🔗Open to the BMB community via Zoom - DM for link by Friday June 20
🗓️Tuesday, June 24
⏰2 p.m. ET
📍 Becton Dickinson Hall (W1020)
🔗Open to the BMB community via Zoom - DM for link by Friday June 20
Expanding the chemical space of flavins with pentacyclic architecture
->Nature | More info from EcoSearch
->Nature | More info from EcoSearch
Expanding the chemical space of flavins with pentacyclic architecture
To this end, we designed a pentacyclic scaffold to induce significant changes in the electronic structure, thereby overcoming the intrinsic limits of natural or synthetic flavins in their optical and redox properties (Fig. 1d). Specifically, we hypothesized that anchoring the...
www.nature.com
April 15, 2025 at 6:21 AM
Expanding the chemical space of flavins with pentacyclic architecture
https://www.europesays.com/1996773/
Synthesis and characterization of O-PF To this end, we designed a pentacyclic scaffold to induce significant changes in…
https://www.europesays.com/1996773/
Synthesis and characterization of O-PF To this end, we designed a pentacyclic scaffold to induce significant changes in…
Expanding the chemical space of flavins with pentacyclic architecture - EUROPE SAYS
To this end, we designed a pentacyclic scaffold to induce significant changes in the electronic structure, thereby overcoming the intrinsic limits of natural
www.europesays.com
April 15, 2025 at 6:05 AM
Expanding the chemical space of flavins with pentacyclic architecture
https://www.europesays.com/1996773/
Synthesis and characterization of O-PF To this end, we designed a pentacyclic scaffold to induce significant changes in…
https://www.europesays.com/1996773/
Synthesis and characterization of O-PF To this end, we designed a pentacyclic scaffold to induce significant changes in…
SHOW ME YOUR YESTERDAY WORDS (actually, as much as I love unicorns and stealing them, I also love when I put in a fairly obscure word and, while it’s a low %, it’s been used by a few folk already - I feel less alone in my love of words!)
February 28, 2025 at 10:14 AM
SHOW ME YOUR YESTERDAY WORDS (actually, as much as I love unicorns and stealing them, I also love when I put in a fairly obscure word and, while it’s a low %, it’s been used by a few folk already - I feel less alone in my love of words!)
The last research article of @danieleggerichs.bsky.social PhD thesis was just published, supported by wonderful collaboration with the @mattevilab.bsky.social it's part of a special collection for #flavins and #flavoproteins, and we report on a #flavin #oxidase
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Kinetic and structural investigation of the 4-allyl syringol oxidase from Streptomyces cavernae
4-Phenol oxidases are proposed to be involved in the utilization of lignin-derived aromatic compounds. While enzymes with selectivity towards 4-hydrox…
www.sciencedirect.com
January 25, 2025 at 12:11 PM
The last research article of @danieleggerichs.bsky.social PhD thesis was just published, supported by wonderful collaboration with the @mattevilab.bsky.social it's part of a special collection for #flavins and #flavoproteins, and we report on a #flavin #oxidase
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Flavins and Flavoproteins in the Neuroimmune Landscape of Stress Sensitization and Major Depressive Disorder #inflammation #neuroinflammation #depression www.tandfonline.com/doi/pdf/10.2...
www.tandfonline.com
January 19, 2025 at 3:52 AM
Flavins and Flavoproteins in the Neuroimmune Landscape of Stress Sensitization and Major Depressive Disorder #inflammation #neuroinflammation #depression www.tandfonline.com/doi/pdf/10.2...
Ribo Flavins sounds like a hobbit name.
of all the flavins ribo is my favorite
December 31, 2024 at 4:15 AM
Ribo Flavins sounds like a hobbit name.
of all the flavins ribo is my favorite
December 31, 2024 at 3:57 AM
of all the flavins ribo is my favorite
#ResearchAlert ☀️ Flavins, nature-inspired molecules like vitamin B2, are explored by Austrian, Czech and Korean researchers as metal-free photosensitizers for sustainable green hydrogen production, enhancing photocatalytic hydrogen evolution efficiency. 👉 http://go.jku.at/w24bk8
December 26, 2024 at 9:00 AM
#ResearchAlert ☀️ Flavins, nature-inspired molecules like vitamin B2, are explored by Austrian, Czech and Korean researchers as metal-free photosensitizers for sustainable green hydrogen production, enhancing photocatalytic hydrogen evolution efficiency. 👉 http://go.jku.at/w24bk8
ribo is perhaps my most favorite of all the flavins. you?
December 20, 2024 at 3:08 PM
ribo is perhaps my most favorite of all the flavins. you?
of all the flavins ribo is my favorite
June 14, 2024 at 11:52 PM
of all the flavins ribo is my favorite