Agree flozins are generally low-risk, but without real, proven efficacy data am I just causing financial toxicity in an already strapped population? #NephJC
February 11, 2026 at 2:46 PM
Agree flozins are generally low-risk, but without real, proven efficacy data am I just causing financial toxicity in an already strapped population? #NephJC
I know everything is crazy but let's celebrate some wins. I diagnosed a patient with new onset diabetes and heart failure last June, initial A1c 14% EF 21%
As of last week, EF has improved to 35% A1c is 6.2% (!!!!) and patient has lost about 40lbs to a near normal BMI. (Tirzepatide + flozins!)
As of last week, EF has improved to 35% A1c is 6.2% (!!!!) and patient has lost about 40lbs to a near normal BMI. (Tirzepatide + flozins!)
February 11, 2026 at 12:58 PM
I know everything is crazy but let's celebrate some wins. I diagnosed a patient with new onset diabetes and heart failure last June, initial A1c 14% EF 21%
As of last week, EF has improved to 35% A1c is 6.2% (!!!!) and patient has lost about 40lbs to a near normal BMI. (Tirzepatide + flozins!)
As of last week, EF has improved to 35% A1c is 6.2% (!!!!) and patient has lost about 40lbs to a near normal BMI. (Tirzepatide + flozins!)
Bluesky's Top 10 Trending Words (past 60min):
💨x1* - epstein 🔓
💨x1* - democracy 🔓
💨x1* - gaza 🔓
💨x100 - 힐말고
💨x100 - 컨버스였어
💨x88 - maquiagem
💨x1* - ukraine 🔓
💨x61 - derretendo
💨x50 - tumbler
💨x47 - falso
*🔓 = Unlocked Emergency Words (see img)
#FreePalestine 🇵🇸
(Something not right? Reply!)
![Emoji Legend
💨x# | "Increased Trending Rate" for a Word (meaningful value; "💨x8 - burger" will mean "burger" is trending at 8 times its own normal rate for this time of day)
🔓 | "Unlocked" Ongoing Emergency Word (such words are not weighted down by their own previous usage; their *ongoing* increased usage--weeks, months, years--would otherwise move them down the list.)
[PREVIOUSLY USED]
⚠️💨# | "Trend Strength Rating"
⚠️🌀💨 | "Trend Strength Rating" (see above)
⚠️🌀 CAT. # | [same; "CAT." = Category, like hurricane]
💬# | 10min Post Count
🆎# | 10min Word Count
🙂# | 10min Emoji Count](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:k43ha6nlknmdw4owymqnvcat/bafkreigp6bgag3jzkool6uxrujpcrwtn6zkd7cbfrmevhaxaqhhewgolmu@jpeg)
February 11, 2026 at 3:02 AM
February 11, 2026 at 2:38 AM
February 11, 2026 at 2:20 AM
Bluesky's Top 10 Trending Words (past 10min):
💨x1* - epstein 🔓
💨x62 - respeita
💨x41 - tumbler
💨x40 - comemorar
💨x33 - indict
💨x32 - trindade
💨x31 - pirro
💨x1* - democracy 🔓
💨x25 - 힐말고
💨x25 - 컨버스였어
*🔓 = Unlocked Emergency Words (see img)
#ListenToBlackVoices
(Something not right? Reply!)
![Emoji Legend
💨x# | "Increased Trending Rate" for a Word (meaningful value; "💨x8 - burger" will mean "burger" is trending at 8 times its own normal rate for this time of day)
🔓 | "Unlocked" Ongoing Emergency Word (such words are not weighted down by their own previous usage; their *ongoing* increased usage--weeks, months, years--would otherwise move them down the list.)
[PREVIOUSLY USED]
⚠️💨# | "Trend Strength Rating"
⚠️🌀💨 | "Trend Strength Rating" (see above)
⚠️🌀 CAT. # | [same; "CAT." = Category, like hurricane]
💬# | 10min Post Count
🆎# | 10min Word Count
🙂# | 10min Emoji Count](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:mcb6n67plnrlx4lg35natk2b/bafkreigp6bgag3jzkool6uxrujpcrwtn6zkd7cbfrmevhaxaqhhewgolmu@jpeg)
February 11, 2026 at 2:20 AM
February 11, 2026 at 2:11 AM
February 11, 2026 at 2:05 AM
#NephJC
Jeyakumar Meyyappan from Lucknow, India . No COI
Infections are a concern in kidney transplant patients. Wondering if Flozins are worth even a micro minimal risk . Good topic to be discussed
Jeyakumar Meyyappan from Lucknow, India . No COI
Infections are a concern in kidney transplant patients. Wondering if Flozins are worth even a micro minimal risk . Good topic to be discussed
February 11, 2026 at 2:05 AM
#NephJC
Jeyakumar Meyyappan from Lucknow, India . No COI
Infections are a concern in kidney transplant patients. Wondering if Flozins are worth even a micro minimal risk . Good topic to be discussed
Jeyakumar Meyyappan from Lucknow, India . No COI
Infections are a concern in kidney transplant patients. Wondering if Flozins are worth even a micro minimal risk . Good topic to be discussed
⏰30 min before the #NephJC chat
There has been limited research on SGLT2i in renal transplant recipients till date, and this is the compilation of currently available data. #NephJC
Are you pumped to know how and how well #Flozins work in transplanted patients?
Let's deep dive in a few minutes!
There has been limited research on SGLT2i in renal transplant recipients till date, and this is the compilation of currently available data. #NephJC
Are you pumped to know how and how well #Flozins work in transplanted patients?
Let's deep dive in a few minutes!
February 11, 2026 at 1:30 AM
The Effect of SGLT2 Inhibitors aka #Flozins on Blood Pressure in Relation to Baseline Kidney Function: A Systematic Literature Review and Data Analysis
🔗 academic.oup.com/ajh/article-... 🔒
🔗 academic.oup.com/ajh/article-... 🔒
The Effect of SGLT2 Inhibitors on Blood Pressure in Relation to Baseline Kidney Function: A Systematic Literature Review and Data Analysis
AbstractBACKGROUND. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce both systolic blood pressure (SBP) and diastolic blood pressure (DBP). The gl
academic.oup.com
February 10, 2026 at 12:01 PM
The Effect of SGLT2 Inhibitors aka #Flozins on Blood Pressure in Relation to Baseline Kidney Function: A Systematic Literature Review and Data Analysis
🔗 academic.oup.com/ajh/article-... 🔒
🔗 academic.oup.com/ajh/article-... 🔒
Here is the VA for the INFINITI study of SGLT2i in transplant patients by @glomerican.bsky.social #NephSky #Flozins #Flozination
www.nephjc.com/news/2026/2/8/infiniti-the-visual-abstract
www.nephjc.com/news/2026/2/8/infiniti-the-visual-abstract
INFINITI: The Visual Abstract — NephJC
SGLT2i have reshaped cardiorenal care, but kidney transplant recipients have mostly been left out of the story. INFINITI starts to close that gap, testing the safety and physiology of dapagliflozin in...
www.nephjc.com
February 9, 2026 at 12:40 PM
Here is the VA for the INFINITI study of SGLT2i in transplant patients by @glomerican.bsky.social #NephSky #Flozins #Flozination
www.nephjc.com/news/2026/2/8/infiniti-the-visual-abstract
www.nephjc.com/news/2026/2/8/infiniti-the-visual-abstract
Hey #NephSky
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
To INFINITI and Beyond: SGLT2 Inhibitors in Kidney Transplant Patients — NephJC
This week, we aim for an INFINITe allograft lifespan. or flozination in kidney transplant.
www.nephjc.com
February 8, 2026 at 11:25 PM
Hey #NephSky
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
2/10/26 at 9 pm EST we'll discuss
#Flozinating into the Future & Beyond...
SGLT2i in kidney transplant recipients.
What's the latest evidence of risk/benefit?
Do #Flozins act mechanistically the same in de-innervated kidneys?
Come chat.
www.nephjc.com/news/inifinti-flozins-transplant
My clinic recently got an embedded pharmacist. She's made it her mission to get as many folks off sulfonylureas and on to flozins and GLP1s simply for the morbidity/mortality benefit alone. She also helps manage our tough HTN and HF patients. She's been a god send for chronic disease management
One of the keys to expanding the scope of primary care is inclusion of really-good pharmacists.
January 29, 2026 at 5:01 PM
My clinic recently got an embedded pharmacist. She's made it her mission to get as many folks off sulfonylureas and on to flozins and GLP1s simply for the morbidity/mortality benefit alone. She also helps manage our tough HTN and HF patients. She's been a god send for chronic disease management
As a PCP I've more or less taken over care of my CKD/DKD patients as my local nephros don't seem to do a great job of managing unless they're approaching dialysis.
We have all the tools now. ARB, flozins, GLP1, MRA etc that it's not that difficult to manage most of them
We have all the tools now. ARB, flozins, GLP1, MRA etc that it's not that difficult to manage most of them
CKD care needs to improve and we have options now to do so!
DKD care could be done by primary care with our help/guidance in tricky situations
GN diagnosis (esp IgA, APOL1) needs to increase since we have (or will have)!options to treat these
@christosargyrop.bsky.social @kidneyboy.bsky.social
DKD care could be done by primary care with our help/guidance in tricky situations
GN diagnosis (esp IgA, APOL1) needs to increase since we have (or will have)!options to treat these
@christosargyrop.bsky.social @kidneyboy.bsky.social
January 20, 2026 at 2:00 AM
As a PCP I've more or less taken over care of my CKD/DKD patients as my local nephros don't seem to do a great job of managing unless they're approaching dialysis.
We have all the tools now. ARB, flozins, GLP1, MRA etc that it's not that difficult to manage most of them
We have all the tools now. ARB, flozins, GLP1, MRA etc that it's not that difficult to manage most of them
But, the vast majority of our best medicines are rooted in nature. From clot busters to cardiac meds.
The Gliptins are the penicillin of this generation. They are fascinating
Every so often humanity gets one right. Statins, Flozins, vaccines for kids...
The Gliptins are the penicillin of this generation. They are fascinating
Every so often humanity gets one right. Statins, Flozins, vaccines for kids...
January 17, 2026 at 1:04 PM
But, the vast majority of our best medicines are rooted in nature. From clot busters to cardiac meds.
The Gliptins are the penicillin of this generation. They are fascinating
Every so often humanity gets one right. Statins, Flozins, vaccines for kids...
The Gliptins are the penicillin of this generation. They are fascinating
Every so often humanity gets one right. Statins, Flozins, vaccines for kids...