Because the thing about vascular tone,
Is not just more or less vasoconstriction,
When tone is reduced,
This is often produced,
By the active process of vasodilatation.
Is not just more or less vasoconstriction,
When tone is reduced,
This is often produced,
By the active process of vasodilatation.
December 15, 2025 at 8:43 AM
Because the thing about vascular tone,
Is not just more or less vasoconstriction,
When tone is reduced,
This is often produced,
By the active process of vasodilatation.
Is not just more or less vasoconstriction,
When tone is reduced,
This is often produced,
By the active process of vasodilatation.
GM 🩸
Being cold increases your blood pressure.
Vasoconstriction reduces blood flow to the skin, so pressure rises in the core.
🧪 Source: Hypertension Journal, 2016
Being cold increases your blood pressure.
Vasoconstriction reduces blood flow to the skin, so pressure rises in the core.
🧪 Source: Hypertension Journal, 2016
December 13, 2025 at 12:07 PM
GM 🩸
Being cold increases your blood pressure.
Vasoconstriction reduces blood flow to the skin, so pressure rises in the core.
🧪 Source: Hypertension Journal, 2016
Being cold increases your blood pressure.
Vasoconstriction reduces blood flow to the skin, so pressure rises in the core.
🧪 Source: Hypertension Journal, 2016
Winter’s Impact on the Body and Biofield
When the temperature falls, the body prioritizes warmth for vital organs through vasoconstriction, redirecting blood flow from the extremities to the core.
When the temperature falls, the body prioritizes warmth for vital organs through vasoconstriction, redirecting blood flow from the extremities to the core.
December 12, 2025 at 9:44 AM
Winter’s Impact on the Body and Biofield
When the temperature falls, the body prioritizes warmth for vital organs through vasoconstriction, redirecting blood flow from the extremities to the core.
When the temperature falls, the body prioritizes warmth for vital organs through vasoconstriction, redirecting blood flow from the extremities to the core.
in addition to low-key medicating ADHD, nicotine (also a favorite of schizophrenic folks) and caffeine also anecdotally help some people with POTS due to vasoconstriction. and POTS is a common component of Long COVID.
Oh boy oh boy oh boy, I can't wait for a whole new generation of folks who insist that they're very normal and neurotypical and not different at all who suddenly fall apart when they lose their stimulant that helps regulate them without being given an acceptable alternative. Just like smoking.
December 11, 2025 at 8:51 AM
in addition to low-key medicating ADHD, nicotine (also a favorite of schizophrenic folks) and caffeine also anecdotally help some people with POTS due to vasoconstriction. and POTS is a common component of Long COVID.
écoute-nous : l'eau trop froide cause de la vasoconstriction, ce qui permet à la brûlure de s'étendre. les 3x15, c'est ce qu'on apprend en école d'infirmière et aux premiers secours
December 7, 2025 at 5:55 PM
écoute-nous : l'eau trop froide cause de la vasoconstriction, ce qui permet à la brûlure de s'étendre. les 3x15, c'est ce qu'on apprend en école d'infirmière et aux premiers secours
BE SAFE! Why cold weather can be harder on dialysis patients.. Vasoconstriction (narrowing of blood vessels), Higher blood pressure risk, Weaker immune system + more infections, Dry skin and poor circulation, ransportation issues, Heart strain..
December 7, 2025 at 5:32 PM
BE SAFE! Why cold weather can be harder on dialysis patients.. Vasoconstriction (narrowing of blood vessels), Higher blood pressure risk, Weaker immune system + more infections, Dry skin and poor circulation, ransportation issues, Heart strain..
This is apparently why women faint more easily than men. They're not weak or squeamish -- they're just experiencing less vasoconstriction when their stress hormones amp up.
December 5, 2025 at 8:37 AM
This is apparently why women faint more easily than men. They're not weak or squeamish -- they're just experiencing less vasoconstriction when their stress hormones amp up.
it’s VERY high intensity cardio, the cold may keep you from realizing you’re getting overheated AND your blood pressure can go up in the cold (vasoconstriction), and the action of throwing a heavy load over your shoulder (above your heart) increases risk of a cardiac event. Be careful!!
November 30, 2025 at 9:22 PM
it’s VERY high intensity cardio, the cold may keep you from realizing you’re getting overheated AND your blood pressure can go up in the cold (vasoconstriction), and the action of throwing a heavy load over your shoulder (above your heart) increases risk of a cardiac event. Be careful!!
i think part of it for me at least is my nervous system just gets triggered at the drop of a hat, so i'm assuming there's so sort of vasoconstriction/dilation nonsense going on whenever i experience A Big Emotion
November 26, 2025 at 1:06 AM
i think part of it for me at least is my nervous system just gets triggered at the drop of a hat, so i'm assuming there's so sort of vasoconstriction/dilation nonsense going on whenever i experience A Big Emotion
- Dysfunction of capillaries leading to hypoperfusion, especially in the brain and muscle, is proposed as a mechanism for fatigue. Endothelial damage & dysfunction, as well as sympathetic vasoconstriction, may create conditions for reduced blood flow and oxygen delivery to neural tissues
November 25, 2025 at 7:24 AM
- Dysfunction of capillaries leading to hypoperfusion, especially in the brain and muscle, is proposed as a mechanism for fatigue. Endothelial damage & dysfunction, as well as sympathetic vasoconstriction, may create conditions for reduced blood flow and oxygen delivery to neural tissues
SuPAR causes renal vasoconstriction and may cause AKI? pubmed.ncbi.nlm.nih.gov/41187619/ what do you say @christosargyrop.bsky.social
#TopNephrology
#TopNephrology
Soluble urokinase receptor is a kidney-specific vasoconstrictor - PubMed
Supported by the National Institutes of Health, University of Southern Denmark, Region of Southern Denmark PhD Fund, OUH-RH Joint Research Fund, Danish Kidney Association's Research Fund, Odense University Hospital Research Fund, Goldsmith A. L. Rasmussen Memorial Fund, Dept. of Anaesthesiology-Inte …
pubmed.ncbi.nlm.nih.gov
November 24, 2025 at 10:27 PM
SuPAR causes renal vasoconstriction and may cause AKI? pubmed.ncbi.nlm.nih.gov/41187619/ what do you say @christosargyrop.bsky.social
#TopNephrology
#TopNephrology
Nope, pressure cause vasoconstriction and lowers the pulse rate, but the co2 absolutely sucks still
November 24, 2025 at 8:08 PM
Nope, pressure cause vasoconstriction and lowers the pulse rate, but the co2 absolutely sucks still
I'm really bummed. I was trying Guanfacine recently too and I had SO much energy and motivation to go OUT and DO THINGS and I was feeling SO GOOD and suddenly it started giving me chest pain too and weird sharp twisty pains all over my torso and arms that my psych thinks was vasoconstriction?
November 24, 2025 at 8:05 AM
I'm really bummed. I was trying Guanfacine recently too and I had SO much energy and motivation to go OUT and DO THINGS and I was feeling SO GOOD and suddenly it started giving me chest pain too and weird sharp twisty pains all over my torso and arms that my psych thinks was vasoconstriction?
Sertraline I’ve had mixed experiences with, while bupropion makes me feel… “tight”… and causes bad vasoconstriction.
November 23, 2025 at 11:03 PM
Sertraline I’ve had mixed experiences with, while bupropion makes me feel… “tight”… and causes bad vasoconstriction.
Agree, much prefer the bit of inotropy and precapillary pulmonary vasoconstriction from NE.
journals.lww.com/cjasn/fullte...
journals.lww.com/cjasn/fullte...
journals.lww.com
November 23, 2025 at 2:26 AM
Agree, much prefer the bit of inotropy and precapillary pulmonary vasoconstriction from NE.
journals.lww.com/cjasn/fullte...
journals.lww.com/cjasn/fullte...
Will also note that dropping more vasoconstriction on top of a regimen of adhd stimulants which are also vasoconstrictors is probably not great
November 22, 2025 at 4:08 PM
Will also note that dropping more vasoconstriction on top of a regimen of adhd stimulants which are also vasoconstrictors is probably not great
vasodilator drugs “potentially worsen oxygenation in conditions where hypoxic pulmonary vasoconstriction has evolved such as pneumonia”https://pubmed.ncbi.nlm.nih.gov/33732460/
November 18, 2025 at 1:58 AM
vasodilator drugs “potentially worsen oxygenation in conditions where hypoxic pulmonary vasoconstriction has evolved such as pneumonia”https://pubmed.ncbi.nlm.nih.gov/33732460/
"Vasoconstriction & adenosine receptors" suggests you rank well above average on medical stuff!
I got as far as "you chew it, it's a stimulant, I think it helps with altitude sickness?"
I got as far as "you chew it, it's a stimulant, I think it helps with altitude sickness?"
November 17, 2025 at 9:54 PM
"Vasoconstriction & adenosine receptors" suggests you rank well above average on medical stuff!
I got as far as "you chew it, it's a stimulant, I think it helps with altitude sickness?"
I got as far as "you chew it, it's a stimulant, I think it helps with altitude sickness?"
Don’t know where I rank among average, but I assume it works similarly to nicotine, you chew on a leaf, and the stimulant is absorbed into the bloodstream via the skin of the gums. From there it probably has effects ranging from vasoconstriction to blocking adenosine receptors.
November 17, 2025 at 9:43 PM
Don’t know where I rank among average, but I assume it works similarly to nicotine, you chew on a leaf, and the stimulant is absorbed into the bloodstream via the skin of the gums. From there it probably has effects ranging from vasoconstriction to blocking adenosine receptors.
Do you mean that there is a separate effect from the obliteration of hypoxic vasoconstriction, mediated through increased CO?
November 17, 2025 at 9:54 AM
Do you mean that there is a separate effect from the obliteration of hypoxic vasoconstriction, mediated through increased CO?
I often wonder when you see patients whose hypoxaemia appears disproportionate to their parenchymal pathology, if impaired pulmonary vasoconstriction due to antihypertensives plays a role. You see some CTs where the consolidated/atelectaric lung looks just so well vascularised 🧐
November 16, 2025 at 7:44 PM
I often wonder when you see patients whose hypoxaemia appears disproportionate to their parenchymal pathology, if impaired pulmonary vasoconstriction due to antihypertensives plays a role. You see some CTs where the consolidated/atelectaric lung looks just so well vascularised 🧐
So do chronically hypercapnic patients have permanently dilated vessels on their heads? Or do they somehow get used to the hypercapnia, and have normal calibre vessels at raised pCO2? If that were the case, then shooting for a normal CO2 would lead to vasoconstriction?
November 14, 2025 at 11:12 AM
So do chronically hypercapnic patients have permanently dilated vessels on their heads? Or do they somehow get used to the hypercapnia, and have normal calibre vessels at raised pCO2? If that were the case, then shooting for a normal CO2 would lead to vasoconstriction?
I think most septic patients at least benefit from noradrenaline’s balance between vasoconstriction and smal ino/chronotropic effect. If you add vaso then deboutamine because CO falls and the LV looks poorer then why not just lore noradrenaline instead.
November 13, 2025 at 7:39 PM
I think most septic patients at least benefit from noradrenaline’s balance between vasoconstriction and smal ino/chronotropic effect. If you add vaso then deboutamine because CO falls and the LV looks poorer then why not just lore noradrenaline instead.
Your body habituates to cold the longer it’s exposed.
Over repeated cold exposure, your shivering and vasoconstriction responses can blunt.
That means your “cold tolerance” can shift.
Source: “Human cold habituation: Physiology, timeline, and modifiers”
Over repeated cold exposure, your shivering and vasoconstriction responses can blunt.
That means your “cold tolerance” can shift.
Source: “Human cold habituation: Physiology, timeline, and modifiers”
November 13, 2025 at 5:12 PM
Your body habituates to cold the longer it’s exposed.
Over repeated cold exposure, your shivering and vasoconstriction responses can blunt.
That means your “cold tolerance” can shift.
Source: “Human cold habituation: Physiology, timeline, and modifiers”
Over repeated cold exposure, your shivering and vasoconstriction responses can blunt.
That means your “cold tolerance” can shift.
Source: “Human cold habituation: Physiology, timeline, and modifiers”
yeah the chronic vasoconstriction isnt worth the positive effects at all
November 13, 2025 at 1:59 AM
yeah the chronic vasoconstriction isnt worth the positive effects at all