Our project, looking at the genetic relationships between immune diseases and psychiatric disorders, has finally been published! Now with gene expression analyses as well as additional sensitivity analyses, thanks to reviewers. Find the full article here: www.nature.com/articles/s41...

Wonderful thread about mentors. @nature.com ‘s mentorship award is open for noms now: www.nature.com/nature/award...

Why do children with Type 1 Diabetes (T1D) often have parents with autoimmune diseases?

Our new study shows parental autoimmune conditions affect offspring’s T1D risk through complex genetic factors, including both HLA and non-HLA variants.

🔗 www.cell.com/cell-genomic...

This is really cool :) I'd love to be a beta tester

The Ripke lab has worked on a new stable release of RICOPILI! Updates include compatibility with GRCh38 and imputation using Minimac4. A software tarball and YAML file are provided to help resolve dependency issues:
github.com/Ripkelab/ric...
Any feedback is highly welcome!
@pgcgenetics.bsky.social

A tour de force review of the connections between between the nervous and immune systems
www.nature.com/articles/s41...

Incredibly proud to see our latest work out in Nature Genetics: www.nature.com/articles/s41...

Here we share our FLAMES framework, which predicts the effector genes in GWAS loci with state-of-the-art precision🔥

Special thanks to @daniposthu.bsky.social

A full thread describing findings below!

impressive, superhelpful review listing 100s tools for GWAS analysis, with important focus on summary data interpretation

biodatamining.biomedcentral.com/articles/10....

We're hiring a postdoc to help shape our autism research program; please consider applying.

www.23andme.com/careers/jobs...

Congrats everyone!!!

Last work tweet of 2024 (maybe 😉): I, Ken Kendler, Brad Verhulst, @jorsmo.bsky.social and @andrewgrotzinger.bsky.social et al in the Psychiatric Genomics Consortium Cross Disorder Group (PGC-CDG) wrote a review on challenges studying cross disorder (psych) genetics: www.nature.com/articles/s41...

🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.

yes unfortunately it's just the code without documentation at the moment. The documentation can be found on this website: sites.google.com/a/broadinsti...

Really cool effort!

How about showing the MHC some love by adding HLA-TAPAS github.com/immunogenomi... and HATK github.com/WansonChoi/H...?

Although not really a post-GWAS tool: RICOPILI for QC and data processing (some much needed updates are underway): github.com/Ripkelab/ric...

Thanks for the valued colleague award @pgcgenetics.bsky.social, which traveled all the way from Singapore to Berlin!

NOW HIRING
#postdocjobs
NIH funding for a #postdoc with interest in complex genetics / computation / analysis
#GWAS #rarevariants #polygenicriskscores
in multiple research contexts:
psychiatric genomics; cognitive genomics; embryo screening...
acnp.org/wp-content/u...