Lightnews — Scholar-powered news

di Bernardo Lab @diegodibi.bsky.social · 16d

Not very surprising…

Reposted by di Bernardo Lab

Arc Institute @arcinstitute.org · 16d

The team is already working to expand the platform’s abilities, including testing in clinically relevant immune and stem cells, and engineering future versions of the system that can rearrange sequences beyond one megabase.

Learn more in the full paper: www.science.org/doi/10.1126/...

Megabase-scale human genome rearrangement with programmable bridge recombinases

Bridge recombinases are naturally occurring RNA-guided DNA recombinases that we previously demonstrated can programmably insert, excise, and invert DNA in vitro and in Escherichia coli. In this study,...

www.science.org

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Reposted by di Bernardo Lab

European Research Council (ERC) @erc.europa.eu · 20d

🧪Roman Jerala @kemijski.bsky.social developed a new method for modular protein design that allows controlled assembly and disassembly.

The work is publicly available and could support advances in synthetic biology.

👉 europa.eu/!4GrrNf

#Biochemistry #Catalysis #GeneEditing @addgene.bsky.social

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Reposted by di Bernardo Lab

Enrico Orsi @eorsi.bsky.social · Sep 12

Please repost!

Postdoc in adaptive laboratory evolution and C1 synthetic metabolism!

Location: DTU Biosustain

🦠🧬🔬

Starting in 01/2026!

Fell free to reach out if you have questions!
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...

efzu.fa.em2.oraclecloud.com

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di Bernardo Lab @diegodibi.bsky.social · Sep 10

Join our lab dibernardo.tigem.it for the #ERC-funded project DIMERCIRCUITS at @tigem.bsky.social. We are building synthetic gene circuits to power next-generation gene and cell therapies. We are looking for candidates with a PhD in #SyntheticBiology or related. Apply by email: [email protected]

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Reposted by di Bernardo Lab

Anthony Vecchiarelli @cellforganized.bsky.social · Aug 26

My MCDB dept is accepting applications for a faculty position at the Assistant Professor level!

Applications Due by October 15, 2025

We welcome applications from all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal levels.

lsa.umich.edu/mcdb/news-ev...

MCDB Opens Search for Faculty | U-M LSA Molecular, Cellular, and Developmental Biology (MCDB)

MCDB welcomes applications at the Assistant Professor level from outstanding biological scientists in all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal le...

lsa.umich.edu

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Reposted by di Bernardo Lab

Olivier Borkowski @oborkowski.bsky.social · Sep 7

Synthetic biology meets diagnostics: Engineering biosensing platforms for rapid and accurate pathogen and viral detection
doi.org/10.1016/j.bi...

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Reposted by di Bernardo Lab

Max-Planck-Gesellschaft @maxplanck.de · Sep 1

The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. www.mpg.de/en/max-planc...

Group photo of postdocs conducting research at a Max Planck Institute

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Reposted by di Bernardo Lab

Thomas Gorochowski @chofski.bsky.social · Sep 1

Come and join us at a free complementary Japan-UK Engineering Biology meeting after the main ESSL conference (essl2025.org/). A few spaces left to some see some of the up and coming superstars of #synbio in the UK!

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Reposted by di Bernardo Lab

Eric Topol @erictopol.bsky.social · Aug 28

Your DNA sequence reveals a rare mutation. Will you get the disease, i.e. penetrance? A new study using machine learning predicts this across 10 common diseases, 1,600 genomic variants
New @science.org
science.org/doi/10.1126/...

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Reposted by di Bernardo Lab

Nature Biotechnology @natbiotech.nature.com · Aug 29

A benchmarking competition improves tools that predict how regulatory regions control gene expression go.nature.com/3NnblYZ
rdcu.be/eCbmL

A community effort to optimize sequence-based deep learning models of gene regulation - Nature Biotechnology

A benchmarking competition improves tools that predict how regulatory regions control gene expression.

go.nature.com

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Reposted by di Bernardo Lab

Olivier Borkowski @oborkowski.bsky.social · Aug 29

Strategies and applications of synthetic cell communication
doi.org/10.1038/s415...

Strategies and applications of synthetic cell communication - Nature Chemical Biology

Recent advances in engineering bottom-up synthetic cells have created powerful compartmentalized biochemical reactors with cell-like abilities. To push the boundaries of the collective capabilities of...

doi.org

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Reposted by di Bernardo Lab

Manuel Thery @manuelthery.bsky.social · Jul 29

EMBL Cell Biology and Biophysics department is searching for a new director. A major position to lead this field in Europe and beyond.
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Head of the Cell Biology and Biophysics Unit

The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organisation, and one of the world’s leading research institutions. An intergovernmental organisation of 29 Member S...

embl.wd103.myworkdayjobs.com

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Reposted by di Bernardo Lab

Nature Biotechnology @natbiotech.nature.com · Jul 23

Optical pooled screening is enhanced by amplification of barcodes before in situ sequencing go.nature.com/3ZVzqOi
rdcu.be/exfh0

Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView - Nature Biotechnology

Optical pooled screening is enhanced by amplification of barcodes before in situ sequencing.

go.nature.com

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di Bernardo Lab @diegodibi.bsky.social · Jul 22

We are hiring a Bioinformatician expert in NGS for our Bioinformatics Core @tigem.bsky.social please share with anyone that may be interested.

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di Bernardo Lab @diegodibi.bsky.social · Jul 15

Today, I’m really happy to host Caleb Bashore from Rice University at Telethon Institute of Genetics and Medicine (TIGEM). He’s doing amazing workin synthetic biology so if you are in the Naples area and wants to attend his seminar today you’re welcome.

www.tigem.it/newsroom/sem...

Caleb J. Bashor, PhD - "Engineering synthetic regulatory circuits in human cells"

www.tigem.it

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di Bernardo Lab @diegodibi.bsky.social · Jul 10

and the editors of the journal were not helpful at all, and so now I will never use PrePrint any longer, unfortunately. In case you want to know more, here is a link: pubpeer.com/publications...

PubPeer - CRISPR perfect adaptation for robust control of cellular imm...

There are comments on PubPeer for publication: CRISPR perfect adaptation for robust control of cellular immune and apoptotic responses (2024)

pubpeer.com

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di Bernardo Lab @diegodibi.bsky.social · Jul 10

I have to say I have very mixed feelings for BioRxiv. Before, I was a staunch believer in preprint. But something happened to me a year back. My manuscript, while in submission, was also on BioRxiv ...and was completely plagiarized,

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Reposted by di Bernardo Lab

Addgene @addgene.bsky.social · Jul 8

Want to become a cloning wizard? 🪄
Our latest blog post is packed with hands-on tips for mastering Modular Cloning — advice on how to prepare for the process, handle reagents, high-throughput methods, and more.
Start your MoClo quest here:
https://twp.ai/4io9Rn

blog.addgene.org

Tips and Tricks for Using Golden Gate Modular Cloning (MoClo)

twp.ai

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Reposted by di Bernardo Lab

Science Magazine @science.org · Jul 3

Exclusive: A major scientific publisher, Taylor & Francis, said it has paused submissions to its journal Bioengineered so editors there can investigate some 1000 of its papers that bear signs they contain manipulated results or came from paper mills. scim.ag/4kjR4la

Journal plagued with problematic papers, likely from paper mills, pauses submissions

The halt will let Taylor & Francis focus on checking Bioengineered’s papers for fraudulent works and paid authorships

scim.ag

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Reposted by di Bernardo Lab

Tom Ellis @proftomellis.bsky.social · Jun 30

We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. imperial.ac.uk/jobs/search-...

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Reposted by di Bernardo Lab

Eddie Lee @spintheory.bsky.social · Jun 29

Are you a #postdoc in the US looking to next steps?

The Austrian Academy of Sciences is opening up 25 fellowships: www.oeaw.ac.at/en/news/25-n...

A great reason to use our visitor program at #Complexity #Science Hub @csh.ac.at and see how you would fit in: csh.ac.at/engage/resea... 🧪🦋

25 new scholarships for US researchers

Fonds Zukunft Österreich (FZÖ) is providing €10 million in funding for an academy program to bring postdocs from the USA to Austria ++ Faßmann: “The right signal in these turbulent times”

www.oeaw.ac.at

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Reposted by di Bernardo Lab

Biocontrol Seminars @bioctrl.bsky.social · Jun 18

📢 The second edition of our Workshop on Biological Control Systems is happening online on 19 Nov 2025, with sessions across Asia, Europe, and the Americas. 📢

Talks & posters abstract submissions: Aug 1 & Aug 15

Keynotes and more info on our website: www.biocontrolseminars.org/workshop-2025