Lightnews — Scholar-powered news

Reposted by Raymundo D Hernandez, PhD

Wendy Xin @droligo.bsky.social · 2d

Huge congrats @amygleichman.bsky.social on this phenomenal study, demonstrating regional differences in astrocyte responses to stroke and a key role for astrocytes in post-stroke angiogenesis and repair!

(see also - gorgeous astrocytes for fluorescence Friday)

www.sciencedirect.com/science/arti...

Fluorescently labeled astrocytes at varying distances from cortical or white matter stroke infarct border

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Reposted by Raymundo D Hernandez, PhD

Salk Institute @salkinstitute.bsky.social · 2d

Congratulations to Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi on winning the 2025 Nobel Prize in Physiology or Medicine for uncovering regulatory T cells — the immune system’s peacekeepers that protect our bodies from attacking themselves.

A thread:

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Reposted by Raymundo D Hernandez, PhD

Nature Portfolio @natureportfolio.nature.com · 2d

Glioblastoma — the deadliest form of brain cancer — alters the calvarial bone and its marrow components, pushing it toward producing more myeloid cells and contributing to an immunosuppressive environment, according to a paper in Nature Neuroscience. go.nature.com/3IDmuXb #medsky 🧪

This is figure 1, which shows GBM induces calvarial bone abnormality and OC activity in several anatomical regions of the calvarium delineating osteogenic edges adjacent to the skull sutures.

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Reposted by Raymundo D Hernandez, PhD

Society for Neuroscience @sfn.org · 3d

Find the mentorship you need!

Gain access to a support network and professional development resources aimed at helping you navigate your neuroscience career with confidence.

Submit your application for the Neuroscience Scholars Program today!

🔗 vist.ly/49vx4

#neurosky

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Reposted by Raymundo D Hernandez, PhD

Nature @nature.com · 3d

How to pause and restart your science career: Funding crises, bereavement and a supervisor’s relocation can derail your career path, but you can overcome them.

go.nature.com/4odnP66

How to pause and restart your science career

Funding crises, bereavement and a supervisor’s relocation can derail your career path, but you can overcome them.

go.nature.com

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Reposted by Raymundo D Hernandez, PhD

Your Local Epidemiologist @ylepidemiologist.bsky.social · 5d

1/ We’re almost a week into the #governmentshutdown. Beyond the headlines, it's triggering a slow-moving breakdown in public health systems services —impacting food programs, disease tracking, and potentially your insurance bill. The longer it goes, the more it will impact public health and you.

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Reposted by Raymundo D Hernandez, PhD

World Women in Neuroscience @worldwomenneuro.bsky.social · 6d

#WorldWomenNeuro is excited to host a Professional Development Workshop, ' Leadership at Every Step of the Journey', at this year’s Society for Neuroscience Annual Meeting in San Diego!

See you at #SfN2025 on Nov 17, 3:00–5:00 PM EST

👉 Learn more: https://shorturl.at/cSJ7R

#WWNevents

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Reposted by Raymundo D Hernandez, PhD

Richard Sever @richardsever.bsky.social · 6d

Diana Bianchi out at NICHHD. Hard to see a good reason for letting such a talented individual go www.science.org/content/arti...

After months in limbo, four NIH institute directors fired

Two leaders removed by Trump administration had hoped to stay at agency as in-house investigators

www.science.org

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Reposted by Raymundo D Hernandez, PhD

PLOS Biology @plosbiology.org · 6d

Astrocytes help control #sleep & arousal. @ashleyingiosi.bsky.social explores a @plosbiology.org study showing that wake-promoting #histamine affects how #astrocytes respond to other signals, reducing awake time via astroglial histamine-1-receptors 🧪 Paper: plos.io/4gRj9Ap Primer: plos.io/47at1Sj

Astroglial H1Rs influence neuromodulatory integration and arousal.

How histamine modulates arousal via astrocytes was investigated in brain slices and mice with (left; green) and without (right; purple) histamine-1-receptor (H1R) expression in astrocytes of the primary visual cortex (V1). Panels below depict, from left to right, that H1R expression in V1 astrocytes: (1) attenuates astroglial calcium (Ca²⁺) responses to norepinephrine (NE) in brain slices; (2) suppresses astroglial Ca²⁺ events during wakefulness; (3) restricts the dynamic range of extracellular adenosine (Ado) around rapid eye movement (REM) sleep transitions (N, non-rapid eye movement sleep; W, wakefulness); and (4) reduces time spent in wakefulness.

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Reposted by Raymundo D Hernandez, PhD

Society for Neuroscience @sfn.org · 6d

Happening tomorrow!

#neurosky #neuroskyence

Society for Neuroscience @sfn.org · 13d

Are you presenting at #SfN25?

Attend this upcoming webinar to learn where to start, how to visualize your ideas using text and figures, present to different audiences, and more.

Register now!

🔗 vist.ly/48mkn

#neurosky #neuroskyence

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Reposted by Raymundo D Hernandez, PhD

Sam Wang @samwang.bsky.social · 6d

Congratulations to Dr. Brunkow, to Princeton, and to her graduate adviser, who based on the published record appears to be Shirley Tilghman!

Princeton University @princeton.edu · 6d

Princeton University alumna Mary Brunkow *91 receives the 2025 Nobel Prize in Physiology or Medicine "for groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.”

Princeton alumna Mary Brunkow *91 receives Nobel Prize in Physiology or Medicine

Brunkow received her Ph.D. from Princeton in 1991 in molecular biology. She shares the award with Fred Ramsdell and Shimon Sakaguchi “for groundbreaking discoveries concerning peripheral immune tolera...

www.princeton.edu

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Reposted by Raymundo D Hernandez, PhD

Alt-NIHscience4ALL @alt-nihscience4all.altgov.info · 11d

NIH staff are wrapping up their orderly shutdown tasks. Which were actually quite chaotic.

Most staff are not allowed to deal with any work-related issues unless excepted/exempt due to patient safety issues.

Review meetings and PI communications with staff are not allowed. Travel is canceled.

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Reposted by Raymundo D Hernandez, PhD

Dan Jagger @auditorynerves.bsky.social · 11d

Open access link to new study in Nature:

Polygenic and developmental profiles of autism differ by age at diagnosis.

🧪🧠 #medsky #neuroskyence
www.nature.com/articles/s41...

Polygenic and developmental profiles of autism differ by age at diagnosis - Nature

A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

www.nature.com

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Reposted by Raymundo D Hernandez, PhD

Elizabeth Sypek @elizabethis.bsky.social · 11d

grants.nih.gov/grants/guide...

NOT-OD-26-004: Information for the NIH Extramural Community During the Lapse of Federal Government Funding

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Information for the NIH Extramural Community During the Lapse of Federal Government Funding NOT-OD-26-004. NIH

grants.nih.gov

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Reposted by Raymundo D Hernandez, PhD

Dr. David Miller 🏳️‍🌈 @davidimiller.bsky.social · 11d

📣 Calling 2nd-year grad students and their mentors:

You just abruptly lost the ability to apply for the NSF grad research fellowship.

Join ~900 others (and growing!) in signing @omfishient.bsky.social's petition to reverse that.

[Or reshare this petition if you're not directly impacted]

Petition to NSF to Restore Eligibility for the 2026 Graduate Research Fellowship Program Competition

laurenkuehne.github.io

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Reposted by Raymundo D Hernandez, PhD

Anita Devineni @anitadevineni.bsky.social · 12d

My department at Emory is a hiring a tenure-track neuroscientist!

Anyone who's talked to me in the last 4 years knows I cannot say enough good things about my dept and the neuroscience community here. My colleagues are so wonderfully supportive. Postdocs, please apply!

apply.interfolio.com/174371

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Reposted by Raymundo D Hernandez, PhD

Science Magazine @science.org · 11d

For the third time in a dozen years, the U.S. scientific community is digging in for a potentially lengthy partial federal government shutdown that promises to disrupt research and funding programs. https://scim.ag/4pQ9y0K

U.S. scientists gird for yet another government shutdown

Political impasse to hobble research agencies—and perhaps enable layoffs

scim.ag

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Reposted by Raymundo D Hernandez, PhD

Dr. David Miller 🏳️‍🌈 @davidimiller.bsky.social · 12d

Needed to take a bit of a social media break for personal reasons, but hopping back on say:

At awe of the civil servants at NSF, NIH, etc.

While Vought uses their jobs/livelihood as a political pawn re: shutdown, their first instinct has remained: how do I support the communities of scientists?

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Reposted by Raymundo D Hernandez, PhD

Cientifico Latino, Inc. @cientificolatino.com · 12d

🎓 Graduate Student Panel on Admissions⁠

Hear from current grad students about:⁠
💡 What admissions committees look for⁠
📝 Tips for writing a strong application⁠
🙋🏽‍♀️ Their experiences applying

📅 Date: Tuesday, 10/7 at 9am ET⁠
🌐 Register: www.eventbrite.com/e/graduate-s...

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Reposted by Raymundo D Hernandez, PhD

Eric Topol @erictopol.bsky.social · 12d

A person's genetics has a role in susceptibility to many diseases (Figure), but has little correlation with how the disease may progress or lead to a fatal outcome.
nature.com/articles/s4158

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Reposted by Raymundo D Hernandez, PhD

DrArchivalGenomics @ehekkala.bsky.social · 12d

🧪🧬🌎❄️🌨️💔

Mother Jones @motherjones.com · 12d

The US is hurtling towards a potential government shutdown if Congress does not pass a budget or short-term funding bill by the end of the month.

The fate of the federal government’s Earth and climate science programs may hang in the balance.

Trump and his minions are eyeing “wholesale destruction” of environmental science

And they may seek to use a government shutdown as the pretext.

www.motherjones.com

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Reposted by Raymundo D Hernandez, PhD

Dave Levitan @davelevitan.bsky.social · 17d

This is interesting — in a paper out today, researchers created an alternate history to estimate what Trump's desired cuts to NIH would look like. Of 557 drugs approved 2000-2023, *more than half* are at least partially linked to NIH research that would have not happened under a 40% reduction.

What if NIH had been 40% smaller?

Replaying history with less NIH funding shows widespread impacts on drug-linked research

www.science.org

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Reposted by Raymundo D Hernandez, PhD

Nature Portfolio @natureportfolio.nature.com · 17d

Why do we still know so little about pregnancy? Claire Richards and Lana McClements write about their Nature Communications paper, explaining why sampling early placental tissue is risky, and how the world’s first bioprinted placenta organoids can help. #Academicsky 🧪

Designer homes for mini-placentas: A bioprinted solution

Mini placentas can be grown in the lab to study pregnancy and complications like preeclampsia. Using 3D printing technology, we have bioprinted the first placental organoids and studied the impact of their environment on cell behaviour.

go.nature.com

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Raymundo D Hernandez, PhD @rhernandezphd.bsky.social · 17d

At its best, science operates to understand truth.

When groups seek to control what is allowed and considered truth, science has lost its inherent value and meaning.

This is a dangerous, slippery slope for us all.

#science #research #epidemiology #censorship

Public Citizen @publiccitizen.bsky.social · 17d

The Trump admin is LITERALLY deleting public information that doesn't align with their warped agenda.

The report said that far-right extremists have killed more Americans than other domestic terrorist groups.

And now - that study is gone.

They're trying to censor reality.

Reposted by Raymundo D Hernandez, PhD

Albert Vilella, PhD. @albertvilella.bsky.social · 17d

A reminder that #biotech is still down since this US administration took office.

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