Lightnews — Scholar-powered news

Reposted by Adam Marblestone

Lean Focused Research Organization @lean-lang.org · 1d

💡Did you know you can run #LeanLang in your browser without installing anything? The Lean Playground provides a full environment for experimentation, learning, and for sharing code snippets with others.

Try it out! live.lean-lang.org

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Andrea Dallapè @daddea.bsky.social · 1d

Wait uh, what?? 🤩

cryoEM papers @cryoempapers.bsky.social · 2d

Ballistic Microscopy (BaM) www.biorxiv.org/content/10.1101/2025.10.07.681030v1 #cryoem

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Advanced Research + Invention Agency (ARIA) @aria-research.bsky.social · 1d

The development of new, transformative material processes has stagnated.

In our new thesis, PD Ivan Jayapurna proposes a ‘Universal Fabricator’ to rapidly discover and develop new processes for the scalable production of advanced materials. ↓

link.aria.org.uk/UF-thesis-BS

Manufacturing Abundance

Ages of human history are defined by materials that transformed societies and mark breakthroughs in mastery over matter. Rather than a single material, the next age will be defined by our ability to a...

link.aria.org.uk

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Edwin Kite @edwinkite.bsky.social · 1d

An Introduction to Mars Terraforming, 2025 Workshop Summary
arxiv.org/abs/2510.07344

An Introduction to Mars Terraforming, 2025 Workshop Summary

Terraforming Mars is an age old science fiction concept now worth revisiting through the lens of modern science and technology. This document serves as a summary of contemporary ideas about Mars terra...

arxiv.org

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Adam Marblestone @adammarblestone.bsky.social · 2d

I have never seen a better conference name

xenaproject.bsky.social @xenaproject.bsky.social · 2d

ItaLean : formal maths and AI in Italy (Bologna), Dec 2025. Lectures, hands-on tutorials, research talks from academia and industry etc. Register here pitmonticone.github.io/ItaLean2025/

ItaLean 2025

pitmonticone.github.io

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xenaproject.bsky.social @xenaproject.bsky.social · 2d

ItaLean : formal maths and AI in Italy (Bologna), Dec 2025. Lectures, hands-on tutorials, research talks from academia and industry etc. Register here pitmonticone.github.io/ItaLean2025/

ItaLean 2025

pitmonticone.github.io

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Nicole Rust @nicolecrust.bsky.social · 3d

Please spread the word! I am recruiting a PhD student this cycle (Fall 2026 start) to join my team in a new venture: the neuroscience of mood.

If you are curious to learn more, this short talk provides a good overview of why, what and how.

www.youtube.com/watch?v=gjIK...

Nicole Rust - The representation of mood in the primate insula (May 6, 2025)

YouTube video by Simons Foundation

www.youtube.com

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Derek Lowe @dereklowe.bsky.social · 3d

I don’t think I’ve ever had more fun in the lab than when I was making MOFs myself (and trying to use them for small-molecule X-ray structure determination). So let me celebrate by posting a few of the MOF crystals I prepared:

Bright green transparent metal-organic framework crystals prepared with copper and a “multipronged” carboxylic acid ligand. The crystals formed blocky roughly rectangular pieces with some very large emerald-like chunks.

Pink/red transparent metal-organic framework crystals prepared with cobalt and a “multipronged” carboxylic acid ligand. The crystals formed as a mixture of long rectangular types and aggregated chunks.

Purple transparent metal-organic framework crystals prepared with cobalt and a “multipronged” carboxylic acid ligand. The crystals formed long slightly blocky needles.

Clear transparent metal-organic framework crystals prepared with zirconium and a “multipronged” carboxylic acid ligand. The crystals formed chunky hexagons.

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Timothy Bredy @twbredy.bsky.social · 3d

Say what? 👍

Ryan Flynn @raflynn5.bsky.social · 4d

We’re excited to report work led by postdoc Jennifer Porat in the lab, finding that DNA accumulates on the surface of living cells and that the secreted extracellular protein DNASE1L3 can modulate its levels on B and T cells. With a new twist for ATAC-seq as well www.biorxiv.org/content/10.1...

DNASE1L3 surveils mitochondrial DNA on the surface of distinct mammalian cells

The extracellular space is a critical environment for discriminating self versus non-self nucleic acids and initiating the appropriate immune responses through signaling cascades to relay information ...

www.biorxiv.org

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Eugene Vinitsky 🍒 @eugenevinitsky.bsky.social · 3d

Soooooo when is bluesky deploying bridging systems
arxiv.org/abs/2301.09976

Bridging Systems: Open Problems for Countering Destructive Divisiveness across Ranking, Recommenders, and Governance

Divisiveness appears to be increasing in much of the world, leading to concern about political violence and a decreasing capacity to collaboratively address large-scale societal challenges. In this wo...

arxiv.org

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Sarah Lempriere @sarahlempriere.bsky.social · 7d

I love these new layers of complexity that people are discovering in the brain! Dendrites of different neurons can connect via nanotubes, which transport calcium and cargo such as amyloid-beta www.science.org/doi/10.1126/...

Hidden networks in the brain

Dendritic nanotubes extend brain connectivity beyond synapses

www.science.org

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Ryan Flynn @raflynn5.bsky.social · 5d

Lead by postdoc in the lab Ruiqi Ge and in collaboration with Bob Coffey’s lab, we are happy to share rPAL-seq for rapid and sensitive sequencing based profiling of glycoRNAs @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

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Greg Jefferis @jefferis.bsky.social · 6d

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Male CNS Connectome

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

www.janelia.org

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Neuroengineering @neuroengineering.bsky.social · 6d

Precision Neuroscience published their high-density ECoG in Nature Biomed. Eng.

The startup shows a 1,024-channel grid implanted through a cortical slit in pigs, and intraoperative neural recordings and stimulation in five humans at sub-mm resolution.

#neuroskyence @precisionneuro.bsky.social

Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation - Nature Biomedical Engineering

A 1,024-channel microelectrode array is delivered to the brain cortex via a minimally invasive incision in the skull and dura, and allows recording, stimulation and neural decoding across large portions of the brain in porcine models and human neurosurgical patients.

www.nature.com

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Nikolai Slavov @slavov-n.bsky.social · 8d

Earlier this year, @parallelsq.bsky.social hosted a research fest.

We began with a broad perspective:
◾️ A century of remarkable progress! Proteomics drove conceptual discoveries and medical treatments.

Listen to what's next!

Proteomics: The arc of progress
youtu.be/Sc2QLXb84XI?...

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Anders Sandberg @arenamontanus.bsky.social · 8d

Announcing ALLFED's new study in Earth System Dynamics: Even modest crop declines from nuclear war or infrastructure collapse could trigger cascading food trade disruptions. Global food systems are more fragile than we think. allfed.info/research/pub...

Food trade disruption after global catastrophes

Jehn et. al (2024) highlight the vulnerability of the global food trade system to major disruptions caused by global catastrophic risks (GCR), such as an Abrupt Sunlight Reduction Scenario (ASRS) resu...

allfed.info

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Ed Boyden @eboyden3.bsky.social · 9d

Wonderful to collaborate with, and to support as an advisor, E11 Bio - and to announce PRISM, a technology for mapping brains in a self-correcting way, by barcoding neurons followed by expansion microscopy! Thread below by E11 Bio CEO Andrew Payne, with preprint at, www.biorxiv.org/content/10.1...

Andrew Payne @andrewcpayne.bsky.social · 10d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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Joergen Kornfeld @jmrko.bsky.social · 10d

Long story short: PRISM has the potential to solve the connectomics reconstruction bottleneck for good. Fantastic collaboration with E11, MIT, and the Crick!

Andrew Payne @andrewcpayne.bsky.social · 10d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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kathleen leeper @kathleen-leeper.bsky.social · 10d

hello, we are working on brain mapping and now you can read about it! it has beautiful neurons (shout out to cell 1492), cool multiplexing tricks, and cell barcodes. there are live data links, my first addgene collection and much much more

Andrew Payne @andrewcpayne.bsky.social · 10d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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Sven Truckenbrodt @sventruckenbrodt.bsky.social · 19d

The Molecular Brain Mapping group at the MRC-LMB is hiring! 🌈🧠

I'm looking for people who are excited about developing multimodal analysis and visualization tools to capture the "hidden connectome," in a highly intersectional environment exploring ideas in meta-science.

mrc.tal.net/vx/mobile-0/...

Imaging Data Engineer - Neurobiology - Dr Sven Truckenbrodt - LMB 2697 - Medical Research Council

Location: Cambridge. Vacancy: Imaging Data Engineer - Neurobiology - Dr Sven Truckenbrodt - LMB 2697. Closing Date: 09/10/2025, 23:55

mrc.tal.net

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Sven Truckenbrodt @sventruckenbrodt.bsky.social · 10d

E11's self-correcting neuron barcoding technology PRISM is getting us closer to scalable connectomics — this will enable connectomics research we've been dreaming of for decades 🌈🧠🔬

Andrew Payne @andrewcpayne.bsky.social · 10d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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Sumner L. Norman @sumnerln.bsky.social · 10d

Our sister FRO E11 Bio is well on their way to mapping every neuron in the brain. Check out their work on PRISM out today!

Andrew Payne @andrewcpayne.bsky.social · 10d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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Reposted by Adam Marblestone

Addgene @addgene.bsky.social · 10d

New AAV tools from @e11bio.bsky.social! PRISM uses protein-tag barcodes for high-throughput reconstruction of neurons and other cell-labeling applications. https://twp.ai/4iruEB

A 3D rendering of a network of neurons from a rectangular volume. Each neuron is filled with a slightly different color, making each cell body and its projections distinct from its neighbors.

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Konrad Kording @kordinglab.bsky.social · 10d

Such a cool achievement!

Andrew Payne @andrewcpayne.bsky.social · 10d

E11 Bio is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves.

Read more: e11.bio/blog/prism

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