(((Dr Hannah Wirtshafter))) 🔬
@aheadofthenerve.bsky.social
Proud scientist. BRAIN K99/R00. HPC experimental & computational systems neuro. Ephys4life.
Postdoc @NUFeinbergMed w @Disterhoftlab & @SaraASolla.
PhD @MITbiology w/ Matt Wilson
🔬🧠🐀🌈
Postdoc @NUFeinbergMed w @Disterhoftlab & @SaraASolla.
PhD @MITbiology w/ Matt Wilson
🔬🧠🐀🌈
Pinned
A universal hippocampal memory code across animals and environments
How learning is affected by context is a fundamental question of neuroscience, as the ability to generalize learning to different contexts is necessary for navigating the world. An example of swift co...
www.biorxiv.org
🚨 New #Blueprint🚨 Ever wondered how the HPC supports learning across different contexts? My newest, a combo of experimental and comp neuro, w @SaraASolla & @DisterhoftLab, uncovers a 'universal' memory code in the HPC—consistent across animals and environments! 🧵👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!
www.cam.ac.uk/jobs/univers...
www.cam.ac.uk/jobs/univers...
University Assistant/Associate Professor in Control Theory and Systems Biology
Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group
www.cam.ac.uk
December 3, 2025 at 12:19 PM
We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!
www.cam.ac.uk/jobs/univers...
www.cam.ac.uk/jobs/univers...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Joint modelling of brain and behaviour dynamics with artificial intelligence
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Joint modelling of brain and behaviour dynamics with artificial intelligence - Nature Reviews Neuroscience
Artificial intelligence is rapidly advancing our mechanistic understanding of the shared structure between the brain and higher-order behaviours. In this Review, Mathis and Mathis synthesize state-of-...
www.nature.com
December 3, 2025 at 4:59 PM
Joint modelling of brain and behaviour dynamics with artificial intelligence
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
0/10 Thanks for the interest in our preprint. Some takes say it negates or fully supports the “manifold hypothesis”, neither quite right. Our results show that if you only focus on the manifold capturing most of task-related variance, you could miss important dynamics that actually drive behavior.
“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”
Neural dynamics outside task-coding dimensions drive decision trajectories through transient amplification
Most behaviors involve neural dynamics in high-dimensional activity spaces. A common approach is to extract dimensions that capture task-related variability, such as those separating stimuli or choice...
www.biorxiv.org
December 2, 2025 at 7:48 AM
0/10 Thanks for the interest in our preprint. Some takes say it negates or fully supports the “manifold hypothesis”, neither quite right. Our results show that if you only focus on the manifold capturing most of task-related variance, you could miss important dynamics that actually drive behavior.
Reposted by (((Dr Hannah Wirtshafter))) 🔬
excited to embark on a new era @nsb-mbl.bsky.social w directors Lauren O'Connell (Stanford) + Bruce Carlson (WashU), new 6-week format for graduate students, postdocs & investigators. learn state-of-the-art methods & approach towards neural systems of behavior. deadline Feb 2. tinyurl.com/57476k4v
December 2, 2025 at 10:29 AM
excited to embark on a new era @nsb-mbl.bsky.social w directors Lauren O'Connell (Stanford) + Bruce Carlson (WashU), new 6-week format for graduate students, postdocs & investigators. learn state-of-the-art methods & approach towards neural systems of behavior. deadline Feb 2. tinyurl.com/57476k4v
Reposted by (((Dr Hannah Wirtshafter))) 🔬
@aatishb.bsky.social got me on the record. “My colleagues did an outstanding job to work their butts off to approve things.” I swear it's true. It's still true at #NIH.
The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
www.nytimes.com
December 2, 2025 at 1:25 PM
@aatishb.bsky.social got me on the record. “My colleagues did an outstanding job to work their butts off to approve things.” I swear it's true. It's still true at #NIH.
Reposted by (((Dr Hannah Wirtshafter))) 🔬
"Neuroscientists need better training in computational methods."
We got you.
Join us in July: neuromatch.io/courses/
Our #ComputationalNeuroscience course is the perfect way to gain practical experience and build a strong foundation in this field.
We got you.
Join us in July: neuromatch.io/courses/
Our #ComputationalNeuroscience course is the perfect way to gain practical experience and build a strong foundation in this field.
As neuroscience expands, @thetransmitter.bsky.social asks, how can neuroscience training programs best meet the needs of students and the field? See what survey respondents had to say: www.thetransmitter.org/training/how...
#neuroskyence #StateOfNeuroscience
#neuroskyence #StateOfNeuroscience
Survey: How will neuroscience training need to change?
Training in computational neuroscience, data science and statistics is needed but must be balanced with grounding in the scientific method, say respondents.
www.thetransmitter.org
December 1, 2025 at 2:51 PM
"Neuroscientists need better training in computational methods."
We got you.
Join us in July: neuromatch.io/courses/
Our #ComputationalNeuroscience course is the perfect way to gain practical experience and build a strong foundation in this field.
We got you.
Join us in July: neuromatch.io/courses/
Our #ComputationalNeuroscience course is the perfect way to gain practical experience and build a strong foundation in this field.
"The inevitability and superfluousness of cell types in spatial cognition". Intuitive cell types are found in random artificial networks using the same selection criteria neuroscientists use with actual data. elifesciences.org/reviewed-pre... 1/2
elifesciences.org
November 25, 2025 at 7:53 PM
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Applications due December 1st!
Come work with us!
Come work with us!
Two weeks left to apply! MIT's Department of Brain and Cognitive Sciences is seeking a tenure-track Assistant Professor, working with nonhuman animals in some way. Application deadline is Dec. 1. Full posting: academicjobsonline.org/ajo/jobs/30586
Massachusetts Institute of Technology, Department of Brain & Cognitive Sciences
Job #AJO30586, Assistant Professor level or higher, Department of Brain & Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, US
academicjobsonline.org
November 24, 2025 at 9:41 PM
Applications due December 1st!
Come work with us!
Come work with us!
Reposted by (((Dr Hannah Wirtshafter))) 🔬
NIH announces 16% more proposals will be considered for funding! drugmonkey.wordpress.com/2025/11/24/n...
NIH announces 16% more proposals will be considered for funding!
Dudes! It’s good news. LOL. A recent NIH Notice (NOT-OD-26-012) includes the first formal announcement of an expanded triage rate that will be used for the next two rounds (at least) of study…
drugmonkey.wordpress.com
November 24, 2025 at 9:11 PM
NIH announces 16% more proposals will be considered for funding! drugmonkey.wordpress.com/2025/11/24/n...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
It feels like the converastion about manifold dimensionality is back, so I thought I'd share a paper that explains nicely why measuring the "embedding dimensionality" of a manifold (e.g., counting PCs) can be very different from its actual "intrinsic dimensionality (DoFs)
doi.org/10.1016/j.co...
doi.org/10.1016/j.co...
Redirecting
doi.org
November 24, 2025 at 2:29 AM
It feels like the converastion about manifold dimensionality is back, so I thought I'd share a paper that explains nicely why measuring the "embedding dimensionality" of a manifold (e.g., counting PCs) can be very different from its actual "intrinsic dimensionality (DoFs)
doi.org/10.1016/j.co...
doi.org/10.1016/j.co...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Foraging as an ethological framework for neuroscience
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
Foraging as an ethological framework for neuroscience
The study of foraging is central to a renewed interest in naturalistic behavior in neuroscience. Applying a foraging framework grounded in behavioral …
www.sciencedirect.com
November 14, 2025 at 9:23 AM
Foraging as an ethological framework for neuroscience
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
From the amazing @lauragrima.bsky.social and colleagues - definitely looking forward to reading this!
#neuroskyence #psychscisky #cognition
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Want to help shape the SCENE collaboration?! Join us as an executive director: www.cam.ac.uk/jobs/scene-m...
SCENE Manager
The Simons Collaboration on Ecological Neuroscience (SCENE): SCENE is an international consortium of 20 leading researchers in the fields of Computational, Systems and Cognitive Neuroscience, and
www.cam.ac.uk
November 13, 2025 at 5:32 PM
Want to help shape the SCENE collaboration?! Join us as an executive director: www.cam.ac.uk/jobs/scene-m...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Our new paper in @natcomms.nature.com introduces improv, a flexible software platform that integrates models with experiments in real-time. Traditional experiments collect all data first, then analyze it later. With improv, models analyze data as it streams in and actively guide what to do next.
November 13, 2025 at 3:45 PM
Our new paper in @natcomms.nature.com introduces improv, a flexible software platform that integrates models with experiments in real-time. Traditional experiments collect all data first, then analyze it later. With improv, models analyze data as it streams in and actively guide what to do next.
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Tomorrow: Samuel Muscinelli, assistant professor of Neurobiology at the University of Chicago, joins us for the NITMB Seminar Series!
You can participate in-person at NITMB or virtually tomorrow at 10am CT
www.nitmb.org/nitmb-semina...
You can participate in-person at NITMB or virtually tomorrow at 10am CT
www.nitmb.org/nitmb-semina...
November 13, 2025 at 3:04 PM
Tomorrow: Samuel Muscinelli, assistant professor of Neurobiology at the University of Chicago, joins us for the NITMB Seminar Series!
You can participate in-person at NITMB or virtually tomorrow at 10am CT
www.nitmb.org/nitmb-semina...
You can participate in-person at NITMB or virtually tomorrow at 10am CT
www.nitmb.org/nitmb-semina...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Alert for scientists: NIH institute director vacancies are posted! Please apply so we get actual scientists in these positions instead of just political appointees!!!!
More new NIH institute and center director positions posted
with a closing date of 11/26/25.
hr.nih.gov/careers/open...
These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ...
1/3
with a closing date of 11/26/25.
hr.nih.gov/careers/open...
These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ...
1/3
hr.nih.gov
November 13, 2025 at 3:06 PM
Alert for scientists: NIH institute director vacancies are posted! Please apply so we get actual scientists in these positions instead of just political appointees!!!!
Reposted by (((Dr Hannah Wirtshafter))) 🔬
#CNS2026 | Satellite - International Sleep Replay Workshop
Friday, March 6, 2026, 8:00 am - 6:00 pm, Salon F
The workshop is open to all: experience with sleep research is not required. Register here: isrw.bio.uci.edu Registration Deadline, February 15th
@cogneuronews.bsky.social #SleepRelay
Friday, March 6, 2026, 8:00 am - 6:00 pm, Salon F
The workshop is open to all: experience with sleep research is not required. Register here: isrw.bio.uci.edu Registration Deadline, February 15th
@cogneuronews.bsky.social #SleepRelay
Workshops, Socials & Special Events - Cognitive Neuroscience Society
March 7 – 10, 2026 CNS Account CNS 2026 | Workshops, Socials & Special Events SESSION DATE TIME LOCATION Satellite – International Sleep Replay Workshop Friday, March 6 8:00 am – 6:00 pm Salon F Wor...
www.cogneurosociety.org
November 13, 2025 at 4:21 PM
#CNS2026 | Satellite - International Sleep Replay Workshop
Friday, March 6, 2026, 8:00 am - 6:00 pm, Salon F
The workshop is open to all: experience with sleep research is not required. Register here: isrw.bio.uci.edu Registration Deadline, February 15th
@cogneuronews.bsky.social #SleepRelay
Friday, March 6, 2026, 8:00 am - 6:00 pm, Salon F
The workshop is open to all: experience with sleep research is not required. Register here: isrw.bio.uci.edu Registration Deadline, February 15th
@cogneuronews.bsky.social #SleepRelay
Reposted by (((Dr Hannah Wirtshafter))) 🔬
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
2026 Lake Conference
Join the Allen Institute for Cell Science and Circuit Neuroscience Basel in Seattle, Washington, April 20–22, 2026, for a 3 day conference, Modeling...
alleninstitute.org
November 13, 2025 at 4:51 PM
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
This is the reality for many grantees at Cornell and elsewhere with frozen grants: after a certain amount of time the loss (in money, research time, or personnel) is unrecoverable.
Paying $60 million doesn't get that all back.
Paying $60 million doesn't get that all back.
Both stop work orders on my two grants have now been released. Unfortunately, the agency for one grant reallocated the funds, so likely those won't come back.
This has gone on for seven months now, and there was no clear point to any of it. I am grateful to colleagues for stepping in to help out.
This has gone on for seven months now, and there was no clear point to any of it. I am grateful to colleagues for stepping in to help out.
November 7, 2025 at 8:51 PM
This is the reality for many grantees at Cornell and elsewhere with frozen grants: after a certain amount of time the loss (in money, research time, or personnel) is unrecoverable.
Paying $60 million doesn't get that all back.
Paying $60 million doesn't get that all back.
Reposted by (((Dr Hannah Wirtshafter))) 🔬
I wrote a thing on episodic memory and systems consolidation. I hope you all enjoy it and/or find it interesting.
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
Episodic memories are highly dynamic and change in nonlinear ways over time. This dynamism is not captured by existing systems consolidation theories …
www.sciencedirect.com
November 3, 2025 at 12:56 PM
I wrote a thing on episodic memory and systems consolidation. I hope you all enjoy it and/or find it interesting.
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Statistical Learning in the Wild: Rethinking Discovery in the AI and Data Era
Thank you for joining us at today's NITMB Seminar, featuring @jsb-ucla.bsky.social, Professor and Program Head of the Biostatistics Program at @fredhutch.org!
🎥 Talk recording 🔗 in reply ⬇️
Thank you for joining us at today's NITMB Seminar, featuring @jsb-ucla.bsky.social, Professor and Program Head of the Biostatistics Program at @fredhutch.org!
🎥 Talk recording 🔗 in reply ⬇️
November 7, 2025 at 6:28 PM
Statistical Learning in the Wild: Rethinking Discovery in the AI and Data Era
Thank you for joining us at today's NITMB Seminar, featuring @jsb-ucla.bsky.social, Professor and Program Head of the Biostatistics Program at @fredhutch.org!
🎥 Talk recording 🔗 in reply ⬇️
Thank you for joining us at today's NITMB Seminar, featuring @jsb-ucla.bsky.social, Professor and Program Head of the Biostatistics Program at @fredhutch.org!
🎥 Talk recording 🔗 in reply ⬇️
can someone say if this is actually setting a precedent for other schools or is a one off/not applicable to other schools?
Woaw, big news. Good news.
Thanks @sthilaire.bsky.social for the Intel
@wesa.fm
www.wesa.fm/health-scien...
Thanks @sthilaire.bsky.social for the Intel
@wesa.fm
www.wesa.fm/health-scien...
NIH under Trump wanted to slash indirect research costs to 15%. Pitt just signed an agreement at 59%
Pitt and the Department of Health and Human Services have agreed to maintain the school’s current 59% reimbursement rate for ancillary research costs through 2029.
www.wesa.fm
November 7, 2025 at 4:50 PM
can someone say if this is actually setting a precedent for other schools or is a one off/not applicable to other schools?
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Reposted by (((Dr Hannah Wirtshafter))) 🔬
Are you a mathematician or biologist curious about the intersection of mathematics in biology?
Our upcoming workshop, Expanding the Palette of Mathematics in Biology, is your opportunity to discover mathematical biology and explore your work in new theoretical ways!
www.nitmb.org/expanding-pa...
Our upcoming workshop, Expanding the Palette of Mathematics in Biology, is your opportunity to discover mathematical biology and explore your work in new theoretical ways!
www.nitmb.org/expanding-pa...
November 6, 2025 at 8:30 PM
Are you a mathematician or biologist curious about the intersection of mathematics in biology?
Our upcoming workshop, Expanding the Palette of Mathematics in Biology, is your opportunity to discover mathematical biology and explore your work in new theoretical ways!
www.nitmb.org/expanding-pa...
Our upcoming workshop, Expanding the Palette of Mathematics in Biology, is your opportunity to discover mathematical biology and explore your work in new theoretical ways!
www.nitmb.org/expanding-pa...
Reposted by (((Dr Hannah Wirtshafter))) 🔬
New data showing massive increase in forward funding obligations to R01s as of this summer
More context about the why & disastrous implications here:
www.forbes.com/sites/brucel...
bsky.app/profile/drug...
More context about the why & disastrous implications here:
www.forbes.com/sites/brucel...
bsky.app/profile/drug...
November 5, 2025 at 6:35 PM
New data showing massive increase in forward funding obligations to R01s as of this summer
More context about the why & disastrous implications here:
www.forbes.com/sites/brucel...
bsky.app/profile/drug...
More context about the why & disastrous implications here:
www.forbes.com/sites/brucel...
bsky.app/profile/drug...