Alexa Sadier
@aigverte.bsky.social
CNRS PI at Institut des Sciences de l'Evolution de Montpellier | Evo-devo - Bats - Teeth - Dev Constraints - Adaptation | Evolution on Earth and beyond | ERC NOVELTEETH |
Co-host @podcastscience | Cham steepskier
website: alexasadier.com
Co-host @podcastscience | Cham steepskier
website: alexasadier.com
Pinned
Alexa Sadier
@aigverte.bsky.social
· Sep 24
Comme il y a beaucoup de nouveaux arrivants, c'est le moment d'une nouvelle présentation ! Je suis chercheuse en biologie évolutive du développement et dans mon équipe, nous essayons de comprendre comment et par quels mécanismes les espèces (et surtout les chiroptères !! 🦇) se diversifient 👇🧵
Reposted by Alexa Sadier
By studying #primates and closely related species, this new #RSOS study examines the evolution of the #cochlea, the mammalian hearing organ: royalsocietypublishing.org/doi/10.1098/...
November 22, 2025 at 10:01 AM
By studying #primates and closely related species, this new #RSOS study examines the evolution of the #cochlea, the mammalian hearing organ: royalsocietypublishing.org/doi/10.1098/...
Reposted by Alexa Sadier
Les universités françaises sont sommées d’à la fois concurrencer Oxford et le MIT et fournir les services
d’un community college auprès de publics en difficulté, le tout à bon marché et avec une bureaucratie
paralysante. Ensuite, on reproche aux universitaires de ne pas y parvenir.
d’un community college auprès de publics en difficulté, le tout à bon marché et avec une bureaucratie
paralysante. Ensuite, on reproche aux universitaires de ne pas y parvenir.
November 21, 2025 at 11:57 AM
Les universités françaises sont sommées d’à la fois concurrencer Oxford et le MIT et fournir les services
d’un community college auprès de publics en difficulté, le tout à bon marché et avec une bureaucratie
paralysante. Ensuite, on reproche aux universitaires de ne pas y parvenir.
d’un community college auprès de publics en difficulté, le tout à bon marché et avec une bureaucratie
paralysante. Ensuite, on reproche aux universitaires de ne pas y parvenir.
Reposted by Alexa Sadier
Wisconsin Evolution is accepting applications for our Seminar Series' Early Career Scientist Award. Come share your evolution research and visit UW-Madison's evolution community. Open to grad students and postdocs (<5 yrs post PhD) from outside UW-Madison.
Apply by Dec 15th here: shorturl.at/4a4O6
Apply by Dec 15th here: shorturl.at/4a4O6
Early Career Scientist Awards 2026
Application to the UW-Madison Evolution Seminar Series - Early Career Scientist Awards.
urldefense.com
November 19, 2025 at 8:55 PM
Wisconsin Evolution is accepting applications for our Seminar Series' Early Career Scientist Award. Come share your evolution research and visit UW-Madison's evolution community. Open to grad students and postdocs (<5 yrs post PhD) from outside UW-Madison.
Apply by Dec 15th here: shorturl.at/4a4O6
Apply by Dec 15th here: shorturl.at/4a4O6
Reposted by Alexa Sadier
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics
Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.
www.nature.com
November 18, 2025 at 12:00 PM
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Reposted by Alexa Sadier
@elizabethsibert.bsky.social & @garethjfraser.bsky.social & Rubin et al's latest IOB paper has incredible figures!
Be sure to read
"Quantifying the Denticle Multiverse..."
doi.org/10.1093/iob/...
our latest #morphology work involving #Elasmobranch #Denticles
#science #sharks #biologists
Be sure to read
"Quantifying the Denticle Multiverse..."
doi.org/10.1093/iob/...
our latest #morphology work involving #Elasmobranch #Denticles
#science #sharks #biologists
November 18, 2025 at 12:39 PM
@elizabethsibert.bsky.social & @garethjfraser.bsky.social & Rubin et al's latest IOB paper has incredible figures!
Be sure to read
"Quantifying the Denticle Multiverse..."
doi.org/10.1093/iob/...
our latest #morphology work involving #Elasmobranch #Denticles
#science #sharks #biologists
Be sure to read
"Quantifying the Denticle Multiverse..."
doi.org/10.1093/iob/...
our latest #morphology work involving #Elasmobranch #Denticles
#science #sharks #biologists
Reposted by Alexa Sadier
Hi, I’m David Brückner @davidbrueckner.bsky.social.
I’ll take you through how cells in a tissue can use information distributed by biochemical gradients to make decisions, and how we can measure such positional information.
buff.ly/RFxVeHh
I’ll take you through how cells in a tissue can use information distributed by biochemical gradients to make decisions, and how we can measure such positional information.
buff.ly/RFxVeHh
November 15, 2025 at 8:00 AM
Hi, I’m David Brückner @davidbrueckner.bsky.social.
I’ll take you through how cells in a tissue can use information distributed by biochemical gradients to make decisions, and how we can measure such positional information.
buff.ly/RFxVeHh
I’ll take you through how cells in a tissue can use information distributed by biochemical gradients to make decisions, and how we can measure such positional information.
buff.ly/RFxVeHh
Reposted by Alexa Sadier
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
November 14, 2025 at 4:08 PM
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
Reposted by Alexa Sadier
Still looking for our perfect doctoral candidate as part of @evomg-dn.bsky.social - come and join us to work on the evolutionary pressures that shape gene expression and disease in the uterus!
Please RT (or is it RB? not sure how our lingo has changed!)
Please RT (or is it RB? not sure how our lingo has changed!)
🚨 15 days left to apply!
Be part of EvoMG-DN and advance your PhD career in evolutionary genomics.
👉 www.evomg-dn.eu
#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope #EUResearch #ResearchOpportunities #PhDPositions
Be part of EvoMG-DN and advance your PhD career in evolutionary genomics.
👉 www.evomg-dn.eu
#PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope #EUResearch #ResearchOpportunities #PhDPositions
November 14, 2025 at 10:22 AM
Still looking for our perfect doctoral candidate as part of @evomg-dn.bsky.social - come and join us to work on the evolutionary pressures that shape gene expression and disease in the uterus!
Please RT (or is it RB? not sure how our lingo has changed!)
Please RT (or is it RB? not sure how our lingo has changed!)
Reposted by Alexa Sadier
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
November 13, 2025 at 8:34 PM
NEW pub in @science.org 🥳
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?
For over 15 years, #phylogenomic studies have been divided.
We provide new evidence suggesting that...
🔗: www.science.org/doi/10.1126/...
Reposted by Alexa Sadier
Nature research paper: Convergent genome evolution shaped the emergence of terrestrial animals
go.nature.com/4i0i61w
go.nature.com/4i0i61w
Convergent genome evolution shaped the emergence of terrestrial animals - Nature
Comparisons of 154 genomes from 21 animal phyla and outgroups have been used to reconstruct ancestral adaptation to life on land across 11 distinct terrestrialization events, revealing strong evidence for convergent genomic evolution across the animal kingdom and recurring periods of terrestrial colonization.
go.nature.com
November 13, 2025 at 9:18 AM
Nature research paper: Convergent genome evolution shaped the emergence of terrestrial animals
go.nature.com/4i0i61w
go.nature.com/4i0i61w
Reposted by Alexa Sadier
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
November 12, 2025 at 4:49 AM
Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.
(Please repost to reach a broad audience.)
(Please repost to reach a broad audience.)
Reposted by Alexa Sadier
[ #VeilleESR #LRU ] « On va dans le mur » : des présidents d’université dénoncent un sous-financement chronique
par @cberthelemy.bsky.social
Très intéressant : CY Université est dans la même panade, malgré des indicateurs hors normes, montrant un grand respect des injonctions politiques.
par @cberthelemy.bsky.social
Très intéressant : CY Université est dans la même panade, malgré des indicateurs hors normes, montrant un grand respect des injonctions politiques.
« On va dans le mur » : des présidents d’université dénoncent un sous-financement chronique
Conditions d’études dégradées, risque de fermeture de formation, manque de titulaires pour coordonner les parcours... Les universités manque
www.leparisien.fr
November 11, 2025 at 12:26 PM
[ #VeilleESR #LRU ] « On va dans le mur » : des présidents d’université dénoncent un sous-financement chronique
par @cberthelemy.bsky.social
Très intéressant : CY Université est dans la même panade, malgré des indicateurs hors normes, montrant un grand respect des injonctions politiques.
par @cberthelemy.bsky.social
Très intéressant : CY Université est dans la même panade, malgré des indicateurs hors normes, montrant un grand respect des injonctions politiques.
Reposted by Alexa Sadier
My book 'The Tree of Life' is published in the USA and Canada today.
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
November 11, 2025 at 12:01 PM
My book 'The Tree of Life' is published in the USA and Canada today.
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
Available as book, on kindle and as audio.
I would be really grateful for reposts.
www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
Reposted by Alexa Sadier
Conrad Hal Waddington was born OTD in 1905.
His “epigenetic landscape” is a diagrammatic representation of the constraints influencing embryonic development.
On his 50th birthday, his colleagues gave him a pinball machine on the model of the epigenetic landscape.
🧪 🦫🦋 🌱🐋 #HistSTM #philsci #evobio
His “epigenetic landscape” is a diagrammatic representation of the constraints influencing embryonic development.
On his 50th birthday, his colleagues gave him a pinball machine on the model of the epigenetic landscape.
🧪 🦫🦋 🌱🐋 #HistSTM #philsci #evobio
November 8, 2025 at 4:03 PM
Reposted by Alexa Sadier
🦇 #NameThatBat ! Help us choose collective nouns for bats this autumn: www.bats.org.uk/news/2025/11... .
Halloween may be over — but we still need your help to #NameThatBat! Join in and vote in Bat Conservation Trust's first bat naming competition.
Halloween may be over — but we still need your help to #NameThatBat! Join in and vote in Bat Conservation Trust's first bat naming competition.
November 6, 2025 at 9:26 AM
🦇 #NameThatBat ! Help us choose collective nouns for bats this autumn: www.bats.org.uk/news/2025/11... .
Halloween may be over — but we still need your help to #NameThatBat! Join in and vote in Bat Conservation Trust's first bat naming competition.
Halloween may be over — but we still need your help to #NameThatBat! Join in and vote in Bat Conservation Trust's first bat naming competition.
Reposted by Alexa Sadier
[ #VeilleESR #PLF2026 ] Audition du ministre de l'enseignement supérieur
Retranscription : seafile.unistra.fr/f/be9b46d765...
Je viens de faire un thread de ouatemille posts, qui a foiré et j'ai tour perdu. J'y bosse depuis 4 heures, donc je vais pas refaire. Les principaux trucs.
Retranscription : seafile.unistra.fr/f/be9b46d765...
Je viens de faire un thread de ouatemille posts, qui a foiré et j'ai tour perdu. J'y bosse depuis 4 heures, donc je vais pas refaire. Les principaux trucs.
Audition de M. Philippe Baptiste, ministre de l’enseignement supérieur, de la recherche et de l’espace, sur le projet de loi de finances pour 2026 - Pierre OUZOULIAS
29 octobre 2025
videos.senat.fr
November 5, 2025 at 11:59 AM
[ #VeilleESR #PLF2026 ] Audition du ministre de l'enseignement supérieur
Retranscription : seafile.unistra.fr/f/be9b46d765...
Je viens de faire un thread de ouatemille posts, qui a foiré et j'ai tour perdu. J'y bosse depuis 4 heures, donc je vais pas refaire. Les principaux trucs.
Retranscription : seafile.unistra.fr/f/be9b46d765...
Je viens de faire un thread de ouatemille posts, qui a foiré et j'ai tour perdu. J'y bosse depuis 4 heures, donc je vais pas refaire. Les principaux trucs.
Reposted by Alexa Sadier
Finally out in Elife @elife.bsky.social : well done @joledamoisel.bsky.social ! Convergent iridescence and divergent chemical signals in sympatric sister-species of Amazonian butterflies doi.org/10.7554/eLif...
November 6, 2025 at 9:47 AM
Finally out in Elife @elife.bsky.social : well done @joledamoisel.bsky.social ! Convergent iridescence and divergent chemical signals in sympatric sister-species of Amazonian butterflies doi.org/10.7554/eLif...
Reposted by Alexa Sadier
Very excited to share this collaboration with @pbeldade.bsky.social! We explore how the interaction between immune function and developmental processes shapes morphological plasticity in response to temperature.
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
November 4, 2025 at 4:39 PM
Very excited to share this collaboration with @pbeldade.bsky.social! We explore how the interaction between immune function and developmental processes shapes morphological plasticity in response to temperature.
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
Reposted by Alexa Sadier
#Evolution of complex adaptations can involve changes in multiple traits that lack standalone function. @benitoexplains.bsky.social &co show that leaf masquerade in #katydids evolved via concurrent modification in wing colour & shape, driven by evolutionary synergy @plosbiology.org 🧪 plos.io/4oUE741
November 4, 2025 at 1:55 PM
#Evolution of complex adaptations can involve changes in multiple traits that lack standalone function. @benitoexplains.bsky.social &co show that leaf masquerade in #katydids evolved via concurrent modification in wing colour & shape, driven by evolutionary synergy @plosbiology.org 🧪 plos.io/4oUE741
Reposted by Alexa Sadier
@lucianomartelotto, not on Bluesky, on a new Spatial RNA imaging method, PRISM. www.nature.com/articles/s41... Now added to #SingleCell #Spatial #Method bit.ly/scmethodstable
High-plex spatial RNA imaging in one round with conventional microscopes using color-intensity barcodes - Nature Biotechnology
The 64-plex fluorescence imaging of RNA in tissues is achieved in one imaging cycle
www.nature.com
October 31, 2025 at 10:08 AM
@lucianomartelotto, not on Bluesky, on a new Spatial RNA imaging method, PRISM. www.nature.com/articles/s41... Now added to #SingleCell #Spatial #Method bit.ly/scmethodstable
Hallucinant. C'est inacceptable. J'ai une ERC, que rétrospectivement j'ai eu la chance de rédiger à l'étranger avec un dispositif bien meilleur que ceux qui sont proposés en France et SURTOUT avec de quoi produire des résultats préliminaires que ce soit en terme de mentiring ou de moyens #esr
Quand notre ministre de tutelle nous insulte devant la représentation nationale. "Bande de nuls" "complètement à la ramasse".
Nous reprocher des taux de réussite faible à Horizon Europe et ERC, quand manquent les moyens pour assurer nos missions de service public. Surtout changez rien!👌
Nous reprocher des taux de réussite faible à Horizon Europe et ERC, quand manquent les moyens pour assurer nos missions de service public. Surtout changez rien!👌
October 31, 2025 at 10:29 AM
Hallucinant. C'est inacceptable. J'ai une ERC, que rétrospectivement j'ai eu la chance de rédiger à l'étranger avec un dispositif bien meilleur que ceux qui sont proposés en France et SURTOUT avec de quoi produire des résultats préliminaires que ce soit en terme de mentiring ou de moyens #esr
Reposted by Alexa Sadier
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
October 30, 2025 at 5:50 PM
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
Reposted by Alexa Sadier
ICB's spotlight on
@aigverte.bsky.social co author on
doi.org/10.1093/icb/...
for #BatWeek
connect (@)explorabats Insta
alexasadier.com/index.php/fi...
& check out the trailer for the doc Sadier is part of
with the people of Trinidad (and our research of course)
alexasadier.com/index.php/sc...
@aigverte.bsky.social co author on
doi.org/10.1093/icb/...
for #BatWeek
connect (@)explorabats Insta
alexasadier.com/index.php/fi...
& check out the trailer for the doc Sadier is part of
with the people of Trinidad (and our research of course)
alexasadier.com/index.php/sc...
October 29, 2025 at 11:54 AM
ICB's spotlight on
@aigverte.bsky.social co author on
doi.org/10.1093/icb/...
for #BatWeek
connect (@)explorabats Insta
alexasadier.com/index.php/fi...
& check out the trailer for the doc Sadier is part of
with the people of Trinidad (and our research of course)
alexasadier.com/index.php/sc...
@aigverte.bsky.social co author on
doi.org/10.1093/icb/...
for #BatWeek
connect (@)explorabats Insta
alexasadier.com/index.php/fi...
& check out the trailer for the doc Sadier is part of
with the people of Trinidad (and our research of course)
alexasadier.com/index.php/sc...
Reposted by Alexa Sadier
Les extrêmes mettent en danger notre démocratie mais aussi la science et la santé. J’ai cosigné une tribune publiée dans Le Monde aujourd’hui pour dénoncer les amendements LFI/RN visant à taxer l’expérimentation animale car ils constituent une menace pour la recherche et les découvertes médicales 🔬
Budget 2026 : « La taxation des expérimentations animales mettrait en péril la recherche en France »
TRIBUNE. Dans une tribune au « Monde », des représentants de sociétés savantes, de fondations, d’associations et de réseaux scientifiques mettent en garde contre le dépôt d’amendements au projet de lo...
www.lemonde.fr
October 28, 2025 at 5:55 PM
Les extrêmes mettent en danger notre démocratie mais aussi la science et la santé. J’ai cosigné une tribune publiée dans Le Monde aujourd’hui pour dénoncer les amendements LFI/RN visant à taxer l’expérimentation animale car ils constituent une menace pour la recherche et les découvertes médicales 🔬
Reposted by Alexa Sadier
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social