Andrew Boyce
@andrewboyce.bsky.social
🇨🇦 Assistant Professor @UNMHSC Neurosciences
Exploring spreading depolarization during seizure & stroke using optogenetics, ephys, photometry, & microscopy.
Enthusiastic but mediocre runner & climber.
Thompson, Nägerl & Swayne lab alumnus. (he/him)
Exploring spreading depolarization during seizure & stroke using optogenetics, ephys, photometry, & microscopy.
Enthusiastic but mediocre runner & climber.
Thompson, Nägerl & Swayne lab alumnus. (he/him)
Pinned
Andrew Boyce
@andrewboyce.bsky.social
· Apr 10
Contralesional hippocampal spreading depolarization promotes functional recovery after stroke
Nature Communications - Neural mechanisms underlying deep brain strokes are not fully understood. Here authors demonstrate that spreading depolarizations occur in the intact contralesional...
rdcu.be
Excited to share the culmination of my postdoctoral work in the Thompson Lab out today in Nature Communications!
rdcu.be/ehfWU
rdcu.be/ehfWU
Extremely New Mexico view from my front porch this morning:
November 24, 2025 at 2:50 PM
Extremely New Mexico view from my front porch this morning:
Excited to share the first publication out of my lab!
www.jove.com/t/69418/simu...
We describe the approach that I developed during my postdoc in the Thompson Lab for inducing stroke in behaving mice while recording neuronal activity in the emerging core.
www.jove.com/t/69418/simu...
We describe the approach that I developed during my postdoc in the Thompson Lab for inducing stroke in behaving mice while recording neuronal activity in the emerging core.
November 21, 2025 at 10:21 PM
Excited to share the first publication out of my lab!
www.jove.com/t/69418/simu...
We describe the approach that I developed during my postdoc in the Thompson Lab for inducing stroke in behaving mice while recording neuronal activity in the emerging core.
www.jove.com/t/69418/simu...
We describe the approach that I developed during my postdoc in the Thompson Lab for inducing stroke in behaving mice while recording neuronal activity in the emerging core.
So great to have you for a visit! Looking forward to staying in touch.
Thank you @andrewboyce.bsky.social for hosting me at @unmhsc.bsky.social I had a great time with students and faculty, and learned that Albuquerque's founder was from Asturias (de Grao!), which got me really excited 😅
November 7, 2025 at 9:12 PM
So great to have you for a visit! Looking forward to staying in touch.
Reposted by Andrew Boyce
The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it!
www.fpbase.org/spectra/
www.fpbase.org/spectra/
FPbase Fluorescence Spectra Viewer
An interactive fluorescence spectra viewer to evaluate the spectral properties of fluorescent proteins, organic dyes, filters, and detectors.
www.fpbase.org
November 4, 2025 at 3:03 PM
The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it!
www.fpbase.org/spectra/
www.fpbase.org/spectra/
Reposted by Andrew Boyce
Reposted by Andrew Boyce
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice - Nature Communications
The authors present the adaptive optics system MD-FSS, which allows high-resolution brain imaging in awake mice with rapid aberrations correction against motion. It reveals differences in brain functi...
www.nature.com
October 19, 2025 at 5:49 PM
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Reposted by Andrew Boyce
Huge congrats @amygleichman.bsky.social on this phenomenal study, demonstrating regional differences in astrocyte responses to stroke and a key role for astrocytes in post-stroke angiogenesis and repair!
(see also - gorgeous astrocytes for fluorescence Friday)
www.sciencedirect.com/science/arti...
(see also - gorgeous astrocytes for fluorescence Friday)
www.sciencedirect.com/science/arti...
October 10, 2025 at 5:42 PM
Huge congrats @amygleichman.bsky.social on this phenomenal study, demonstrating regional differences in astrocyte responses to stroke and a key role for astrocytes in post-stroke angiogenesis and repair!
(see also - gorgeous astrocytes for fluorescence Friday)
www.sciencedirect.com/science/arti...
(see also - gorgeous astrocytes for fluorescence Friday)
www.sciencedirect.com/science/arti...
Experienced Albuquerque’s balloon fiesta for the first time today! Very cool.
October 4, 2025 at 2:08 PM
Experienced Albuquerque’s balloon fiesta for the first time today! Very cool.
Really fun weekend exploring Southern NM - stopped in at a roastery in Hatch (home of the chile) & camped near White Sands National Park - this state is so cool!
September 22, 2025 at 6:57 PM
Really fun weekend exploring Southern NM - stopped in at a roastery in Hatch (home of the chile) & camped near White Sands National Park - this state is so cool!
Hippocampal SD on the cover of STM! 😍
The new issue of #ScienceTranslationalMedicine is out!
A clinical study identifies people at risk of renewed COVID-19 infections after mRNA vaccination, researchers probe differences in the viral reservoir between men and women living with HIV, and more. https://scim.ag/3I301m5
A clinical study identifies people at risk of renewed COVID-19 infections after mRNA vaccination, researchers probe differences in the viral reservoir between men and women living with HIV, and more. https://scim.ag/3I301m5
September 17, 2025 at 10:12 PM
Hippocampal SD on the cover of STM! 😍
I’m in the market for a fanless solid state (DPSS) 561 nm laser & both companies I’ve purchased from in the past seem to have either vanished or aren’t replying to my inquiries & quote requests 👻 anyone have a good source?
September 4, 2025 at 9:10 PM
I’m in the market for a fanless solid state (DPSS) 561 nm laser & both companies I’ve purchased from in the past seem to have either vanished or aren’t replying to my inquiries & quote requests 👻 anyone have a good source?
Reposted by Andrew Boyce
Happy to share new paper from MSc grads Myrthe and Jenna. We asked the question, when part of the brain dies during stroke, what happens to local and distant cortical neurons that innervate the stroke site (in S1 cortex) or those that receive outputs? journals.sagepub.com/doi/10.1177/...
Retrograde and anterograde trans-synaptic viral tracing of neuronal connections reveals local and distant effects of ischemic stroke on dendritic spines - Myrthe Van Sprengel, Jenna Butterworth, Patri...
Focal stroke leads to complex neurological disturbances with variable recovery. One explanation for this variability is that stroke disrupts local and remote ne...
journals.sagepub.com
May 27, 2025 at 5:14 AM
Happy to share new paper from MSc grads Myrthe and Jenna. We asked the question, when part of the brain dies during stroke, what happens to local and distant cortical neurons that innervate the stroke site (in S1 cortex) or those that receive outputs? journals.sagepub.com/doi/10.1177/...
Reposted by Andrew Boyce
Hot off the press! We found that electroconvulsive therapy (ECT) induces a previously undescribed, second brain event after seizure, called cortical spreading depolarization (CSD), using optical neuroimaging in both a mouse model to human patients. 🧵 below!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans - Nature Communications
The underlying mechanism of electroconvulsive therapy remains not fully understood. Here, the authors use optical neuroimaging in mice and humans to show that electroconvulsive therapy elicits a secon...
doi.org
May 18, 2025 at 6:03 PM
Hot off the press! We found that electroconvulsive therapy (ECT) induces a previously undescribed, second brain event after seizure, called cortical spreading depolarization (CSD), using optical neuroimaging in both a mouse model to human patients. 🧵 below!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Andrew Boyce
As I transition over to Bluesky I have to plug our new #book. If you haven't already, check out the 2nd edition of The #Hippocampus Book!
academic.oup.com/book/59509?s...
academic.oup.com/book/59509?s...
The Hippocampus Book
Abstract. The Hippocampus Book investigates the structure, function and pathology of the hippocampus and related cortical areas. It highlights the importan
academic.oup.com
April 26, 2025 at 4:27 AM
As I transition over to Bluesky I have to plug our new #book. If you haven't already, check out the 2nd edition of The #Hippocampus Book!
academic.oup.com/book/59509?s...
academic.oup.com/book/59509?s...
Reposted by Andrew Boyce
The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory!
neurojobs.sfn.org/job/38785/po...
neurojobs.sfn.org/job/38785/po...
Postdoctoral fellow - Seizure, spreading depolarization, and memory interactions - University of New Mexico, Albuquerque job with Boyce Lab, Department of Neurosciences, University of New Mexico | 387...
Soon to graduate/recently graduated PhD? Interest in memory disruption? The Boyce lab is recruiting a postdoc! In vivo opto, photometry, ephys!
neurojobs.sfn.org
April 10, 2025 at 10:44 PM
The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory!
neurojobs.sfn.org/job/38785/po...
neurojobs.sfn.org/job/38785/po...
Reposted by Andrew Boyce
I have an opening in my lab for a postdoctoral fellow to work on projects that relate to the mechanisms of neurotransmitter release by dopamine neurons and/or on how inflammatory signals infuence the functionning of these neurons. Please share.
April 24, 2025 at 9:34 PM
I have an opening in my lab for a postdoctoral fellow to work on projects that relate to the mechanisms of neurotransmitter release by dopamine neurons and/or on how inflammatory signals infuence the functionning of these neurons. Please share.
Reposted by Andrew Boyce
mScarlet3-H (aka mYongHong), a highly stable monomeric red fluorescent protein, works well for long-term super-resolution imaging, rapid tissue clearing, and CLEM www.nature.com/articles/s41...
A highly stable monomeric red fluorescent protein for advanced microscopy - Nature Methods
The red fluorescent protein mScarlet3-H is bright, photostable and very robust to high temperature, chaotropic conditions and oxidative environments. mScarlet3-H works well in correlative light and el...
www.nature.com
April 18, 2025 at 2:10 AM
mScarlet3-H (aka mYongHong), a highly stable monomeric red fluorescent protein, works well for long-term super-resolution imaging, rapid tissue clearing, and CLEM www.nature.com/articles/s41...
Reposted by Andrew Boyce
We are very proud to announce the winner of the 2025 CAN New Investigator Award: Dr. Mark Cembrowski, Associate Professor at the University of British Columbia - Read his profile here: can-acn.org/awards/new-i...
April 15, 2025 at 3:04 PM
We are very proud to announce the winner of the 2025 CAN New Investigator Award: Dr. Mark Cembrowski, Associate Professor at the University of British Columbia - Read his profile here: can-acn.org/awards/new-i...
Reposted by Andrew Boyce
Thrilled to share new work from the lab, led by Adam Ramsaran:
authors.elsevier.com/a/1kva73QW8S...
authors.elsevier.com/a/1kva73QW8S...
authors.elsevier.com
April 10, 2025 at 4:52 PM
Thrilled to share new work from the lab, led by Adam Ramsaran:
authors.elsevier.com/a/1kva73QW8S...
authors.elsevier.com/a/1kva73QW8S...
The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory!
neurojobs.sfn.org/job/38785/po...
neurojobs.sfn.org/job/38785/po...
Postdoctoral fellow - Seizure, spreading depolarization, and memory interactions - University of New Mexico, Albuquerque job with Boyce Lab, Department of Neurosciences, University of New Mexico | 387...
Soon to graduate/recently graduated PhD? Interest in memory disruption? The Boyce lab is recruiting a postdoc! In vivo opto, photometry, ephys!
neurojobs.sfn.org
April 10, 2025 at 10:44 PM
The postdoctoral position in my lab at UNM is now posted on NeuroJobs! Check it out if you have experience in in vivo opto, ephys, and/or fiber photometry in behaving mice and an interest in seizure, SD, or memory!
neurojobs.sfn.org/job/38785/po...
neurojobs.sfn.org/job/38785/po...
Excited to share the culmination of my postdoctoral work in the Thompson Lab out today in Nature Communications!
rdcu.be/ehfWU
rdcu.be/ehfWU
Contralesional hippocampal spreading depolarization promotes functional recovery after stroke
Nature Communications - Neural mechanisms underlying deep brain strokes are not fully understood. Here authors demonstrate that spreading depolarizations occur in the intact contralesional...
rdcu.be
April 10, 2025 at 10:41 PM
Excited to share the culmination of my postdoctoral work in the Thompson Lab out today in Nature Communications!
rdcu.be/ehfWU
rdcu.be/ehfWU
Reposted by Andrew Boyce
Science
Hippocampal encoding of memories in human infants
#neuroscience
www.science.org/doi/10.1126/...
Hippocampal encoding of memories in human infants
#neuroscience
www.science.org/doi/10.1126/...
Hippocampal encoding of memories in human infants
Humans lack memories for specific events from the first few years of life. We investigated the mechanistic basis of this infantile amnesia by scanning the brains of awake infants with functional magne...
www.science.org
March 23, 2025 at 12:53 PM
Science
Hippocampal encoding of memories in human infants
#neuroscience
www.science.org/doi/10.1126/...
Hippocampal encoding of memories in human infants
#neuroscience
www.science.org/doi/10.1126/...
Please share! 👀 Postdoc opportunity in my lab at the University of New Mexico. Spreading depolarization & memory interactions.
March 18, 2025 at 8:21 PM
Please share! 👀 Postdoc opportunity in my lab at the University of New Mexico. Spreading depolarization & memory interactions.
Website for the Boyce Lab is live! I couldn't help it and included a bit of a New Mexico colour scheme.
www.boyceneurolab.com
www.boyceneurolab.com
The Boyce Lab
www.boyceneurolab.com
March 17, 2025 at 8:06 PM
Website for the Boyce Lab is live! I couldn't help it and included a bit of a New Mexico colour scheme.
www.boyceneurolab.com
www.boyceneurolab.com
Reposted by Andrew Boyce
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
www.forbes.com
March 13, 2025 at 12:55 AM
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...