Author | Lightnews

Anna Docherty @annadocherty.bsky.social · 7d

Yes, your point was not missed. Same answer for all of them.

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Anna Docherty @annadocherty.bsky.social · 7d

This is a presentation of several separate meta-analyses.

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Anna Docherty @annadocherty.bsky.social · 9d

@niamhmullins.bsky.social @itunuowoyemi.bsky.social @pgcgenetics.bsky.social @ispg.bsky.social

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Anna Docherty @annadocherty.bsky.social · 9d

The PGC Suicide Working Group will provide a symposium at #WCPG2025 🇲🇽 covering our latest multi-ancestry GWAS and CNV meta-analyses, sex-specific meta-analyses, and GxEHR analyses. 🥳

@lcstoshio.bsky.social @andreyshabalin.bsky.social @sarahcolbert.bsky.social @caina89.bsky.social

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Reposted by Anna Docherty

American Foundation for Suicide Prevention @afspnational.bsky.social · 11d

We recently launched The Upright to address the critical gaps in access, effectiveness, and cultural relevance surrounding mental health, suicide prevention, and the lived experience of communities.

Learn more about The Upright and join us for The Summit: www.addevent.com/event/MR2473...

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Reposted by Anna Docherty

Joni Coleman @jonicoleman.bsky.social · Jun 26

Fantastic to see Maria Koromina's great work out in @natneuro.nature.com!

1. A deep look at potential "causal" genetic signals in bipolar disorder
2. A systematic exploration of the analytical choices involved in fine-mapping meta-analysis

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www.nature.com/articles/s41...

Fine-mapping genomic loci refines bipolar disorder risk genes - Nature Neuroscience

This study used fine-mapping to analyze genetic regions associated with bipolar disorder, identifying specific risk genes and providing new insights into the biology of the condition that may guide fu...

www.nature.com

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Reposted by Anna Docherty

Gabriel R. Fries @friesgabriel.bsky.social · Jun 17

Latin America has experienced an increase in suicide rate, contrasting with a global decline. We review possible reasons for this here: www.sciencedirect.com/science/arti...
Led by Dr. Brenda Cabrera-Mendoza and @renatopolimanti.bsky.social, 1st publication from the LAGC Suicide Working Group.

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Reposted by Anna Docherty

Elizabeth Atkinson @egatkinson.bsky.social · Jun 9

We're excited to introduce Tractor-Mix, our new method for GWAS in admixed cohorts with relatedness, led by the fantastic @doubletaotan.bsky.social! Read the full preprint here: www.medrxiv.org/content/10.1...
Thanks to all our amazing collaborators who helped make this work possible!

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Reposted by Anna Docherty

xyxxy.bsky.social @xyxxy.bsky.social · Jun 6

The OpenMx Team is pleased to announce the release of OpenMx version 2.22!: openmx.ssri.psu.edu/node/4942

The big news in this release relates to GREML (Genomic-relatedness-matrix REstricted Maximum-Likelihood): 2 bug-fixes, a patched memory leak, and 2 new features! 1/n

OpenMx 2.22 released! | OpenMx

openmx.ssri.psu.edu

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Tuuli Lappalainen @tuuliel.bsky.social · May 20

Postdoc opportunity! At National Genomics Infrastructure in Uppsala we're looking for a postdoc in genomics R&D. Cutting-edge methods dev in an excellent, international environment at the junction between academia and infrastructure. Deadline May 23!
www.uu.se/en/about-uu/...

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform - Uppsala University

Postdoctoral Researcher, NGI Uppsala, SNP&SEQ Technology Platform, Department of Medical Sciences, Uppsala University

www.uu.se

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Reposted by Anna Docherty

Aysu Okbay @aysuo.bsky.social · May 20

PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social

bioRxivpreprint @biorxivpreprint.bsky.social · May 19

An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference https://www.biorxiv.org/content/10.1101/2025.05.14.653986v1

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Reposted by Anna Docherty

Ted Schwaba @tedmond.bsky.social · May 20

Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...

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Reposted by Anna Docherty

Adam Kucharski @adamjkucharski.bsky.social · May 7

Asked GPT to (impossibly) "write a Bluesky post 100% guaranteed to go viral"

Its suggestion: "just saw a guy confidently order a "croissantini" at the coffee shop and the barista nodded like that was a normal word. i live in a simulation."

Then I said "Make it more viral" and things got weird... 🧵

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Reposted by Anna Docherty

Tuuli Lappalainen @tuuliel.bsky.social · May 5

New preprint! My (now former) postdoc @kvastad.bsky.social led this integration of GWAS and spatial transcriptomics (ST) data to identify tissue structures with enrichment of disease-implicated genes = likely causal drivers of disease biology.
www.biorxiv.org/content/10.1...

Spatial transcriptomics and genetically implicated genes identify putative causal tissue structures for complex traits

Spatially resolved transcriptomics is transforming our understanding of cellular and molecular diversity of tissues. Here, to identify tissue structures that are enriched for putatively causal disease...

www.biorxiv.org

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Reposted by Anna Docherty

Elizabeth F Mattera @lizmattera.bsky.social · Apr 24

@sarahcolbert.bsky.social ‘s #SRS25 presentation: Genome-Wide Association Studies of Suicidal Thoughts and Behaviors in the Psychiatric Genomics Consortium

So incredible!

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Reposted by Anna Docherty

Marios Georgakis @mariosgeorgakis.bsky.social · Apr 24

Massive multi-ancestry GWAS resource for 1,167 clinical traits & diseases in 6 global biobanks (n=1,789,365)

👉29,139 locus-trait pairs
👉2,624 non-overlapping loci across the genome
👉associated with 6 traits each (median)
👉colocalization across traits for 72% of loci [1/3]

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Reposted by Anna Docherty

HiTOP @hitop-system.bsky.social · Apr 16

Please consider helping @kathleenwreardon.bsky.social with this project—and sharing it widely—to improve how we approach teaching HiTOP for a variety of groups and end users

csufull.qualtrics.com/jfe/form/SV_...

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Reposted by Anna Docherty

Amanda Mejia @mandymejia.bsky.social · Apr 7

Excited to be in Salt Lake City for our 2-week NIH training course in Advanced Statistics in Neuroimaging & Genetics! Today-tomorrow I'm teaching longitudinal & Bayesian modeling in neuroimaging to a stellar group of students. medicine.utah.edu/psychiatry/a...

Advanced Statistical Methods in Neuroimaging and Genetics

medicine.utah.edu

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Reposted by Anna Docherty

Fiona Hagenbeek @fionahagenbeek.bsky.social · Apr 6

Our new study in Molecular Psychiatry, in 1528 children and their parents (@ntrbiopsy.bsky.social) shows that indirect genetic effects—where parental genetics shape offspring traits via environmental influences (genetic nurture)—impact DNA methylation of children. doi.org/10.1038/s413... (1/5)

Intergenerational transmission of complex traits and the offspring methylome - Molecular Psychiatry

Molecular Psychiatry - Intergenerational transmission of complex traits and the offspring methylome

doi.org

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Reposted by Anna Docherty

Tim Clancy @viewfromarchstreet.com · Feb 8

On changes to #NIH indirect rates, there is a law in place that prohibits NIH from making such changes without the approval of Congress. See Division D, Title II Section 224 of The Further Consolidated Appropriations Act, 2024 (Public Law No: 118-47) grants.nih.gov/grants/guide...

NOT-OD-24-110: Notice of Legislative Mandates in Effect for FY 2024

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Legislative Mandates in Effect for FY 2024 NOT-OD-24-110. NIH

grants.nih.gov

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International Society of Psychiatric Genetics @ispg.bsky.social · Jan 29

Reminder: We hope you will join us TODAY for a timely and important Member’s Meetup regarding the federal changes and updates affecting the NIH.

📅 Wednesday, January 29
🕗 3 PM EST
📍 us06web.zoom.us/meeting/regi...

#psychiatry #psychiatricgenetics

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Reposted by Anna Docherty

International Society of Psychiatric Genetics @ispg.bsky.social · Jan 24

Unsure how recent changes in U.S. policy regarding the NIH will impact the psychiatric genetics world? You're not alone. Join ISPG for a Member’s Meetup for community discussion and support:

📅 Wednesday, January 29
🕗 3 PM EST
📍 Pre-Register: us06web.zoom.us/meeting/regi...

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Reposted by Anna Docherty

Na Cai @caina89.bsky.social · Jan 20

📢 Quantgen friends:

We will continue to accept applications for the GRC on Quantgen in Feb 2025 till 26 Jan or when we are full, so there is still time to put in an application and join us! 😁

Check out our latest program and apply now!

www.grc.org/quantitative...

2025 Quantitative Genetics and Genomics Conference GRC

The 2025 Gordon Research Conference on Quantitative Genetics and Genomics will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.

www.grc.org

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Reposted by Anna Docherty

Psychiatric Genomics Consortium (PGC) @pgcgenetics.bsky.social · Jan 14

1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in @cellpress.bsky.social.

www.cell.com/cell/fulltex...

A thread 🧵:

Article screenshot of a genome-wide association study of major depression published in the journal Cell

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Anna Docherty @annadocherty.bsky.social · Dec 18

Not sure if someone has said this already, but might be nice to also mention in a review current wrappers/tools facilitating these, eg fuma and ctg-vl?