RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
@aribio.bsky.social
In Ribosome we Trust!!!
Ferreira-Cerca group at the Structural Biology of the Cell laboratory (BIOC) @CNRS / @École polytechnique
More information available at https://ferreiracercalab.com/
#archaea #Ribosome #RNA
Ferreira-Cerca group at the Structural Biology of the Cell laboratory (BIOC) @CNRS / @École polytechnique
More information available at https://ferreiracercalab.com/
#archaea #Ribosome #RNA
Pinned
RNase W, a conserved ribonuclease family with a novel active site
Abstract. Ribosome biogenesis is a complex process requiring multiple precursor ribosomal RNA (rRNA) cleavage steps. In archaea, the full set of ribonuclea
academic.oup.com
Check out our latest publication: academic.oup.com/nar/advance-...
#archaea #ribosome #RNA #Ribonuclease
#archaea #ribosome #RNA #Ribonuclease
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life url: academic.oup.com/nar/article/...
Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life
Abstract. Archaea, a domain of microorganisms found in diverse environments, including the human microbiome, represent the closest known prokaryotic relati
academic.oup.com
February 5, 2026 at 6:53 PM
Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life url: academic.oup.com/nar/article/...
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
#Communiqué 🗞️ Une équipe de chercheurs a identifié le plus ancien vomi fossile terrestre connu à ce jour. Daté d’environ 290 millions d’années (Permien inférieur), soit plusieurs dizaines de millions d’années avant l’apparition des dinosaures.
👉 www.cnrs.fr/fr/presse/un...
👉 www.cnrs.fr/fr/presse/un...
January 30, 2026 at 10:58 AM
#Communiqué 🗞️ Une équipe de chercheurs a identifié le plus ancien vomi fossile terrestre connu à ce jour. Daté d’environ 290 millions d’années (Permien inférieur), soit plusieurs dizaines de millions d’années avant l’apparition des dinosaures.
👉 www.cnrs.fr/fr/presse/un...
👉 www.cnrs.fr/fr/presse/un...
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Online Now: Signaling to make human ribosomes: Connections between the cytoplasm and the nucleolus Online now:
Signaling to make human ribosomes: Connections between the cytoplasm and the nucleolus
Lawrence et al. examine how ribosome production in the eukaryotic nucleolus is coordinated by cytoplasmic processes to maintain appropriate ribosome numbers. The authors highlight regulatory inputs from cytoplasmic signaling, mitosis, and cytoplasmic organelles that converge on nucleolar function, and they discuss how disruption of these pathways contributes to human disease.
dlvr.it
January 28, 2026 at 11:57 PM
Online Now: Signaling to make human ribosomes: Connections between the cytoplasm and the nucleolus Online now:
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism
Thermococcales, archaea from hydrothermal vents, promote iron sulfide precipitation, enabling survival in iron-rich environments. Some cells become encrusted in pyrite and do not survive mineralizati...
enviromicro-journals.onlinelibrary.wiley.com
January 26, 2026 at 5:10 AM
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.
We extend our deepest condolences to his family, friends, and colleagues.
www.embl.org/news/people-...
We extend our deepest condolences to his family, friends, and colleagues.
www.embl.org/news/people-...
January 22, 2026 at 7:40 AM
EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.
We extend our deepest condolences to his family, friends, and colleagues.
www.embl.org/news/people-...
We extend our deepest condolences to his family, friends, and colleagues.
www.embl.org/news/people-...
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
"Use it or lose it." This is great advice for exercise, but when cells need to slow down or go dormant, they need to store ribosomes to recover growth in the future. They use hibernation factors to do this. Here is our latest story on how archaea hibernate ribosomes (1/7):
doi.org/10.64898/202...
doi.org/10.64898/202...
doi.org
January 20, 2026 at 3:53 PM
"Use it or lose it." This is great advice for exercise, but when cells need to slow down or go dormant, they need to store ribosomes to recover growth in the future. They use hibernation factors to do this. Here is our latest story on how archaea hibernate ribosomes (1/7):
doi.org/10.64898/202...
doi.org/10.64898/202...
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Archaeal ribosome hibernation factors on the roll lately, check out the SriA, C; SirB, D with distinct ribosome binding #ribosome #RNASky
A family of archaeal hibernation factors that bind in tandem and protect ribosomes in dormant cells https://www.biorxiv.org/content/10.64898/2026.01.19.700200v1
January 19, 2026 at 9:48 PM
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
A dual-factor complex governs archaeal ribosome hibernation by sensing energy status https://www.biorxiv.org/content/10.64898/2026.01.19.700304v1
January 19, 2026 at 8:45 PM
A dual-factor complex governs archaeal ribosome hibernation by sensing energy status https://www.biorxiv.org/content/10.64898/2026.01.19.700304v1
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
#ResultatScientifique🔎| Quand Candida albicans réduit ses ribosomes, ses cellules deviennent plus fluides, ce qui l’aide à changer de forme et à mieux infecter l’organisme 🍄
✍️ Robert Arkowitz
📕 @natmicrobiol.nature.com | buff.ly/zPSLael
✍️ Robert Arkowitz
📕 @natmicrobiol.nature.com | buff.ly/zPSLael
Fluidité intracellulaire et pouvoir infectieux du champignon Candida albicans
Dans un article publié dans la revue Nature Microbiology, des scientifiques mettent en évidence un mécanisme jusque-là inconnu chez Candida albic
www.insb.cnrs.fr
January 9, 2026 at 1:00 PM
#ResultatScientifique🔎| Quand Candida albicans réduit ses ribosomes, ses cellules deviennent plus fluides, ce qui l’aide à changer de forme et à mieux infecter l’organisme 🍄
✍️ Robert Arkowitz
📕 @natmicrobiol.nature.com | buff.ly/zPSLael
✍️ Robert Arkowitz
📕 @natmicrobiol.nature.com | buff.ly/zPSLael
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Evolution of the ribosomal exit tunnel through the eyes of the nascent chain https://www.biorxiv.org/content/10.64898/2025.12.25.696519v1
December 29, 2025 at 12:46 PM
Evolution of the ribosomal exit tunnel through the eyes of the nascent chain https://www.biorxiv.org/content/10.64898/2025.12.25.696519v1
Lehrstühle an Universitäten: Schafft die Lehrstühle ab! | DIE ZEIT share.google/IJOmJmSPit8Q...
Lehrstühle an Universitäten: Schafft die Lehrstühle ab!
Hierarchien an den Unis sind starr und ungerecht. Manche Hochschulen machen es längst besser.
share.google
December 19, 2025 at 5:22 PM
Lehrstühle an Universitäten: Schafft die Lehrstühle ab! | DIE ZEIT share.google/IJOmJmSPit8Q...
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Delighted to share our new preprint: www.biorxiv.org/content/10.6...
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
Localised activity of reverse gyrase at gene regulatory elements
DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...
www.biorxiv.org
December 11, 2025 at 1:15 PM
Delighted to share our new preprint: www.biorxiv.org/content/10.6...
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Evolutionary Flexibility of Ribosome Biogenesis in Bacteria | Molecular Biology and Evolution | Oxford Academic https://academic.oup.com/mbe/article/42/11/msaf288/8340222?login=false
Evolutionary Flexibility of Ribosome Biogenesis in Bacteria
Abstract. Ribosomes are essential for protein synthesis and require ribosome biogenesis factors for assembly. To uncover the evolutionary diversity of ribo
dx.doi.org
November 24, 2025 at 10:45 AM
Evolutionary Flexibility of Ribosome Biogenesis in Bacteria | Molecular Biology and Evolution | Oxford Academic https://academic.oup.com/mbe/article/42/11/msaf288/8340222?login=false
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Our paper is out! Analysis of 30K+ genomes revealed that CPR bacteria assemble their ribosomes in unconventional ways, and that these assembly processes appear to have co-evolved with ribosome structure. doi.org/10.1093/molb... #Ribosome #Evolution #Patescibacteria #MBE
November 24, 2025 at 1:15 PM
Our paper is out! Analysis of 30K+ genomes revealed that CPR bacteria assemble their ribosomes in unconventional ways, and that these assembly processes appear to have co-evolved with ribosome structure. doi.org/10.1093/molb... #Ribosome #Evolution #Patescibacteria #MBE
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Histones and nucleoid-associated proteins in Methanosarcina acetivorans mediate recovery from stress and stasis https://www.biorxiv.org/content/10.1101/2025.11.24.690127v1
November 25, 2025 at 3:17 AM
Histones and nucleoid-associated proteins in Methanosarcina acetivorans mediate recovery from stress and stasis https://www.biorxiv.org/content/10.1101/2025.11.24.690127v1
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Computational design of cysteine proteases https://www.biorxiv.org/content/10.1101/2025.11.21.689808v1
November 22, 2025 at 2:45 PM
Computational design of cysteine proteases https://www.biorxiv.org/content/10.1101/2025.11.21.689808v1
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Our study on ribonucleotides incorporation the genomes of Haloferax volcanii and Thermococcus barophilus is new published in #NAR #ribonucleasesH
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Validate User
academic.oup.com
November 22, 2025 at 11:01 AM
Our study on ribonucleotides incorporation the genomes of Haloferax volcanii and Thermococcus barophilus is new published in #NAR #ribonucleasesH
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 21, 2025 at 4:20 PM
An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Finally out in @nature.com! We uncovered a mechanistic framework for a general and conserved mRNA nuclear export pathway. www.nature.com/articles/s41.... 1/
November 19, 2025 at 11:22 PM
Finally out in @nature.com! We uncovered a mechanistic framework for a general and conserved mRNA nuclear export pathway. www.nature.com/articles/s41.... 1/
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Hundred-Picolitre Droplet on Demand Tape Drive and XES Prototypes for Time-Resolved Serial Crystallography at VMXi, Diamond Light Source https://www.biorxiv.org/content/10.1101/2025.11.19.689295v1
November 20, 2025 at 3:53 PM
Hundred-Picolitre Droplet on Demand Tape Drive and XES Prototypes for Time-Resolved Serial Crystallography at VMXi, Diamond Light Source https://www.biorxiv.org/content/10.1101/2025.11.19.689295v1
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1
November 19, 2025 at 4:18 PM
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases www.science.org/doi/abs/10.1... #jcampubs
Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases
Although metagenomic sequencing has revealed a rich microbial biodiversity in the mammalian gut, methods to genetically alter specific species in the microbiome are highly limited. Here, we introduce ...
www.science.org
November 13, 2025 at 8:58 PM
Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases www.science.org/doi/abs/10.1... #jcampubs
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Thermophiles don’t just survive heat, they thrive in it. 🔥
They provide heat-stable enzymes, insights into early Earth, and tools for biotech.
Our new thematic issue in #FEMSMicrobiolEcol captures how diverse this field is. Explore the collection👉 buff.ly/kD8fmOL
They provide heat-stable enzymes, insights into early Earth, and tools for biotech.
Our new thematic issue in #FEMSMicrobiolEcol captures how diverse this field is. Explore the collection👉 buff.ly/kD8fmOL
November 14, 2025 at 7:00 AM
Thermophiles don’t just survive heat, they thrive in it. 🔥
They provide heat-stable enzymes, insights into early Earth, and tools for biotech.
Our new thematic issue in #FEMSMicrobiolEcol captures how diverse this field is. Explore the collection👉 buff.ly/kD8fmOL
They provide heat-stable enzymes, insights into early Earth, and tools for biotech.
Our new thematic issue in #FEMSMicrobiolEcol captures how diverse this field is. Explore the collection👉 buff.ly/kD8fmOL
Reposted by RNA & Ribosome Homeostasis Lab @École Polytechnique / @CNRS
Phylogenetic reconciliation supports a methanogenic ancestor of the Archaea and a derived origin for host-associated lineages https://www.biorxiv.org/content/10.1101/2025.11.11.687807v1
November 12, 2025 at 11:32 PM
Phylogenetic reconciliation supports a methanogenic ancestor of the Archaea and a derived origin for host-associated lineages https://www.biorxiv.org/content/10.1101/2025.11.11.687807v1