Adventuring the microscopic and the real world !
First images and final checks
We finally have a working microscope 🔬
After installing the camera, we tackled hardware software communications using @micro-manager.bsky.social
Then we performed usual checks:
1) fluorescent marker
2) scale bar
3) bead solution (PSF)
Microscopes are generally costly equipment, limiting availability in remote areas
Can we make a high-quality microscope cheaply?
This paper makes that vision more real
tinyurl.com/defxwzjf
With a cost below 350 euros, it delivers single-molecule sensitivity
Microscopes are generally costly equipment, limiting availability in remote areas
Can we make a high-quality microscope cheaply?
This paper makes that vision more real
tinyurl.com/defxwzjf
With a cost below 350 euros, it delivers single-molecule sensitivity
First images and final checks
We finally have a working microscope 🔬
After installing the camera, we tackled hardware software communications using @micro-manager.bsky.social
Then we performed usual checks:
1) fluorescent marker
2) scale bar
3) bead solution (PSF)
First images and final checks
We finally have a working microscope 🔬
After installing the camera, we tackled hardware software communications using @micro-manager.bsky.social
Then we performed usual checks:
1) fluorescent marker
2) scale bar
3) bead solution (PSF)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
1) Adaptive thresholding
2)Distance map calculation
3)Watershed transformation
4)Quantification
5)3D rendering
Code : github.com/BorisLouis/S...
Paper: pubs.rsc.org/en/content/a...
#Microscopy #Optics #SciComm #ImageProcessing
1) Adaptive thresholding
2)Distance map calculation
3)Watershed transformation
4)Quantification
5)3D rendering
Code : github.com/BorisLouis/S...
Paper: pubs.rsc.org/en/content/a...
#Microscopy #Optics #SciComm #ImageProcessing
Useful checklist if you are looking to build a new optical system or currently improving one !
analyticalscience.wiley.com/content/arti...
Useful checklist if you are looking to build a new optical system or currently improving one !
analyticalscience.wiley.com/content/arti...
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Meet our latest creation @hofkenslab.bsky.social and @rochalab.bsky.social labs:
A fully custom upright microscope built entirely from scratch, with no microscope body and no commercial frame.
#Optics #SciComm #Microscopy
Meet our latest creation @hofkenslab.bsky.social and @rochalab.bsky.social labs:
A fully custom upright microscope built entirely from scratch, with no microscope body and no commercial frame.
#Optics #SciComm #Microscopy
On this Star Wars Day, I revisited Hacksmith Entertainment Ltd. impressive attempt at creating a real-life lightsaber. If you are into starwars and science, you will probably have seen it !
youtube.com/clip/UgkxTLb...
On this Star Wars Day, I revisited Hacksmith Entertainment Ltd. impressive attempt at creating a real-life lightsaber. If you are into starwars and science, you will probably have seen it !
youtube.com/clip/UgkxTLb...
Has anyone used it? Is it good? 😁
optiland.readthedocs.io/en/latest/in...
Has anyone used it? Is it good? 😁
optiland.readthedocs.io/en/latest/in...
#Microscopy #optics
#DNA-PAINT #tension #integrin #superresolution #adhesion
doi.org/10.1002/advs...
#Microscopy #optics
Chemical & Biomedical Imaging, a new journal from @acs.org, invited us for a special issue on
🔬𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐢𝐧 𝐄𝐧𝐞𝐫𝐠𝐲 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 ☀️ ⚡ 🧪
And we made the cover ! 🎊
Thanks to @alexeychizhik.bsky.social for the amazing design
#Microscopy #Optics #SciComm
Chemical & Biomedical Imaging, a new journal from @acs.org, invited us for a special issue on
🔬𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐢𝐧 𝐄𝐧𝐞𝐫𝐠𝐲 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 ☀️ ⚡ 🧪
And we made the cover ! 🎊
Thanks to @alexeychizhik.bsky.social for the amazing design
#Microscopy #Optics #SciComm
https://go.nature.com/4k0pdH6
https://go.nature.com/4k0pdH6
I’ve been invited to give a talk in San Diego (US) in August this year! 🔬
If you are attending, I would love to connect
arxiv.org/abs/2503.23839
#Microscopy #Optics #SciComm
I’ve been invited to give a talk in San Diego (US) in August this year! 🔬
If you are attending, I would love to connect
arxiv.org/abs/2503.23839
#Microscopy #Optics #SciComm
✅ First, we used the reference laser to project a perfect vertical line through the center of the objective holder. We marked a target on the ceiling for future alignments, an easy trick to save time later
#Optics #Microscopy #SciComm
✅ First, we used the reference laser to project a perfect vertical line through the center of the objective holder. We marked a target on the ceiling for future alignments, an easy trick to save time later
#Optics #Microscopy #SciComm
How do you ensure the optics are aligned straight when building a microscope?
For lasers, I often use diaphragms, but again, how do you ensure they are at the exact same height and lateral position?
#Optics #Microscopy #SciComm
How do you ensure the optics are aligned straight when building a microscope?
For lasers, I often use diaphragms, but again, how do you ensure they are at the exact same height and lateral position?
#Optics #Microscopy #SciComm
Let us know which one is your favourite microscope?
🧪 🔬
Exciting times in @rochalab.bsky.social and @hofkenslab.bsky.social Lab !🧪We're restarting to build microscopes, and I decided to guide two PhD students (Steven Huysecom and Toon Van Roy) through the process.
#Microscopy #optics #SciComm #sts
Exciting times in @rochalab.bsky.social and @hofkenslab.bsky.social Lab !🧪We're restarting to build microscopes, and I decided to guide two PhD students (Steven Huysecom and Toon Van Roy) through the process.
#Microscopy #optics #SciComm #sts
What a wild 72h from 🇧🇪 to 🇸🇬!
Grateful to the organizers who reshuffled things so I could still speak — and even more shocked (and honored!) to get a prize for young speakers. 🔬🧪
Academia is a rollercoaster😅
Singapore, you were stunning 🌿💚
What a wild 72h from 🇧🇪 to 🇸🇬!
Grateful to the organizers who reshuffled things so I could still speak — and even more shocked (and honored!) to get a prize for young speakers. 🔬🧪
Academia is a rollercoaster😅
Singapore, you were stunning 🌿💚
Published in ACS Chemical & Biomedical Imaging (@pubs.acs.org,@acs.org)
💡Read more: pubs.acs.org/doi/10.1021/...
Collaboration: Tokyo tech & KU Leuven (@kuleuvenuniversity.bsky.social)
#Perovskites #SolarCells #imaging #optics
Published in ACS Chemical & Biomedical Imaging (@pubs.acs.org,@acs.org)
💡Read more: pubs.acs.org/doi/10.1021/...
Collaboration: Tokyo tech & KU Leuven (@kuleuvenuniversity.bsky.social)
#Perovskites #SolarCells #imaging #optics
@hofkenslab.bsky.social @borislouis.bsky.social
#MSCActions #Perovskite #ThinFilms #Materials #imaging
@hofkenslab.bsky.social @borislouis.bsky.social
#MSCActions #Perovskite #ThinFilms #Materials #imaging
🔬 We performed high-res imaging of optoelectronic materials & collected 200GB+ of data!
Thanks to Oleksii Nevskyi & @nradmacher.bsky.social for their help we’ll be back! 🚀
🔬 We performed high-res imaging of optoelectronic materials & collected 200GB+ of data!
Thanks to Oleksii Nevskyi & @nradmacher.bsky.social for their help we’ll be back! 🚀
Borrowing principles of AI and super-resolution optical microscopy, 𝐂𝐋𝐈𝐌 provide structural and functional information in photo-active materials.
Read more here: doi.org/10.1002/adma...
🧐 𝐁𝐮𝐭 𝐡𝐨𝐰 𝐝𝐨𝐞𝐬 𝐢𝐭 𝐰𝐨𝐫𝐤?
Borrowing principles of AI and super-resolution optical microscopy, 𝐂𝐋𝐈𝐌 provide structural and functional information in photo-active materials.
Read more here: doi.org/10.1002/adma...
🧐 𝐁𝐮𝐭 𝐡𝐨𝐰 𝐝𝐨𝐞𝐬 𝐢𝐭 𝐰𝐨𝐫𝐤?