Lightnews — Scholar-powered news

Reposted by Emily Bruce

Liz Miller @lizmillercu.bsky.social · 2h

Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.

www.dundee.ac.uk/work-for-us/...

Postdoctoral Research Assistant - MCDB - UOD2016

Closing date: Thursday 6 November 2025, 23:59

www.dundee.ac.uk

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Reposted by Emily Bruce

Hannah R Snyder @hannahrsnyder.bsky.social · 19h

Submitting a grant at this particular moment feels a bit like tossing a rock into the abyss, but hey, at least I am no longer carrying the rock.

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David Ho @davidho.bsky.social · 5d

Hey US scientists, the NY Times wants to hear from you if you've had your funding cut. 🌊🧪

Has Your Scientific Work Been Cut? We Want to Hear.

www.nytimes.com

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NPR @npr.org · 6d

A Cornell University researcher has been developing an artificial heart for children for more than 20 years. Now, his research is on hold and his lab is shut down. n.pr/3KIfcSn

This 4-year-old's heart is failing. A federal grant that might help him was canceled

A Cornell University researcher has been developing an artificial heart for children for more than 20 years. Now, his research is on hold and his lab is shut down.

n.pr

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Caro Goujon @carogoujon.bsky.social · 7d

After years in the making, Joe McKellar @viroscope.bsky.social’s final PhD paper is finally out today in PNAS! 🎉 🎉🎉
www.pnas.org/doi/10.1073/...

Human MX1 orchestrates the cytoplasmic sequestration of neosynthesized influenza A virus vRNPs | PNAS

Interferon-inducible Myxovirus resistance 1 (MX1) proteins are known to restrict influenza A virus (IAV) transcription/replication process. Herein,...

www.pnas.org

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Erik Van Dis @erikvandis.bsky.social · 8d

Timely piece on the importance and safety of “gain-of-function” research, from my brilliant PhD advisor Sarah Stanley www.statnews.com/2025/10/06/g...

The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all

Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.

www.statnews.com

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Reposted by Emily Bruce

Mandy Muller @mandymuller.bsky.social · 9d

🧬 Exciting news from our lab 🧬 The Swiss National Science Foundation (SNSF) has approved our project studying KSHV and RNA decay: our first grant since re-launching the lab in Switzerland 🎉 We’re now looking for a Postdoc and a PhD student to join the team (start date January 2026) - please repost!

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Joey Fishkin @fishkin.bsky.social · 10d

I thought I'd put the administration's proposed "compact" with universities in context, so I wrote the blog post below.

It's especially for journalists covering this story!

Many details about how the compact itself works and why the administration has retreated to this strategy.

Balkinization: The Art of Replacing the Law with the Deal

A group blog on constitutional law, theory, and politics

balkin.blogspot.com

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Emmanuelle Genoyer @immunuelle.bsky.social · 11d

I'm thrilled to announce I'll be joining the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026! My lab will study RNA virus-host interactions with a particular focus on the spatial regulation of viral replication and innate immune activation. genoyerlab.com

Genoyer Lab

genoyerlab.com

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Adriana Forero @adforu.bsky.social · 12d

We are currently in the process of recruiting a technician. 🥼🐭🔬

If you know anyone with enthusiasm to learn new skills and stamina to hear me go on and on about IFNs, please have them reach out to me for more details!

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Pete Buttigieg @petebuttigieg.bsky.social · 12d

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Kris Bertoglio @loadreductionleadership.com · 19d

Loved the last episode of @sciencevs.bsky.social with Ed Yong. "What is happening [to scientific infrastructure] in this country is happening because science is bad for tyrants and always has been. ... You have got to stop the tyranny, not try to make a better case for why science should exist."

How to Smell like a Dog, with Ed Yong

Spotify video

open.spotify.com

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Reposted by Emily Bruce

AZ Faust @azfaust.bsky.social · 15d

Trump cut funding for new biomedical research projects by 37%.

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Siân Culley @superresolusian.bsky.social · 16d

BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...

Bioimage Analysis Specialist | King's College London

www.kcl.ac.uk

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Michael Eisen @mbeisen.bsky.social · 19d

thescientistpapers.substack.com/p/open-lette...

Open letter to HHMI on their Immediate Access to Research Policy

The following is in response to a letter sent to the HHMI community on September 24, 2025 and refers to HHMI’s new Immediate Access to Research Policy. The original letter appears at the bottom below ...

thescientistpapers.substack.com

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Emily Bruce @brucelab.bsky.social · 22d

www.biorxiv.org/content/10.1...

Rab11B is required for binding and entry of recent H3N2, but not H1N1, influenza A isolates

As an obligate intracellular parasite, influenza A virus (IAV) depends on host proteins to complete several important functions, including trafficking viral proteins throughout the cell. Previous work...

www.biorxiv.org

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Emily Bruce @brucelab.bsky.social · 22d

journals.plos.org/plosbiology/...

Variant mutation G215C in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation

Mutations outside the spike protein in SARS-CoV-2, which are likely to impact viral properties, are currently understudied. This study shows that a nucleocapsid protein mutation in the Delta variant e...

journals.plos.org

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Emily Bruce @brucelab.bsky.social · 22d

My last two papers both came out of “weird” bands on western blots. One band that shouldn’t have been there, one band that should have been there and wasn’t.

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Emily Bruce @brucelab.bsky.social · 22d

Westerns are the best technique.

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Emily Bruce @brucelab.bsky.social · 22d

I know someone who calculated the odds of winning the lottery vs getting a NI R01 from NIAID and decided they might be better off investing the start up in the lottery😂

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Emily Bruce @brucelab.bsky.social · 22d

This is as realistic as movie studio execs telling producers to only make block busters.

Drug Monkey @drugmonkey.bsky.social · 22d

All “high risk high reward innovation!” Sounds good to the uninformed but it cannot advance the ball from discovery to clinic.

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Reposted by Emily Bruce

Lynda Coughlan @virusnerdette.bsky.social · Sep 9

I’m curious what they are doing with F awards. Very few seem to have been awarded. We have a student with a fundable F31 score well under the interim payline reviewed LAST AUGUST now waiting 4.5 months after submitting JIT docs 🤬 NIH reporter also showing negligible awards (from NIAID). Devastating

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Emily Bruce @brucelab.bsky.social · Sep 9

Even a descriptive title!

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Reposted by Emily Bruce

David Darmofal @daviddarmofal.bsky.social · Sep 8

We Are Watching a Scientific Superpower Destroy Itself

Opinion | We Are Watching a Scientific Superpower Destroy Itself

www.nytimes.com

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PLOS Biology @plosbiology.org · Sep 3

What causes viral transmission bottlenecks? This study uses barcoded virions to show that in the case of #influenza A #virus, early within-host replication dynamics (rather than a reduced inoculum population) drive loss of diversity during transmission @plosbiology.org 🧪 plos.io/4ngicDK

Population diversity declines between inoculated and exposed guinea pigs. Viral titers in nasal lavage samples are indicated by the overall height of the bar. Red lines show LOD (50 PFU/mL). Colors within the bars represent unique barcodes, and the height of each color indicates barcode frequency within the sample. Plots for individual animals are paired with those of their cage mate. Representative pairs for direct contact (top half) and aerosol (bottom half) exposure are shown from three experimental replicates. Guinea pig ID numbers are shown in the upper right corner of each plot.

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