Cadwell Lab
@cadwelllab.bsky.social
We investigate the interface between the immune system and diverse infectious agents ranging from friendly gut microbes and viruses to disease-causing parasites
Our Lab: https://www.med.upenn.edu/cadwell-lab/
Our Lab: https://www.med.upenn.edu/cadwell-lab/
Reposted by Cadwell Lab
Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
August 18, 2025 at 2:31 PM
Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
Congratulations @christinviral.bsky.social and team for publishing this super cool discovery 😎 www.nature.com/articles/s41.... Here’s a quick summary of our cool findings about how stress due to simple mouse husbandry drives clearance of persistent enteric viral infection 🦠🐭 1/5
Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology
Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...
www.nature.com
June 27, 2025 at 12:23 AM
Congratulations @christinviral.bsky.social and team for publishing this super cool discovery 😎 www.nature.com/articles/s41.... Here’s a quick summary of our cool findings about how stress due to simple mouse husbandry drives clearance of persistent enteric viral infection 🦠🐭 1/5
Reposted by Cadwell Lab
Review @natimmunol.nature.com @cadwelllab.bsky.social
Gene–environment interactions shape the host–microbial interface in inflammatory bowel disease
www.nature.com/articles/s41...
Gene–environment interactions shape the host–microbial interface in inflammatory bowel disease
www.nature.com/articles/s41...
June 17, 2025 at 4:12 PM
Review @natimmunol.nature.com @cadwelllab.bsky.social
Gene–environment interactions shape the host–microbial interface in inflammatory bowel disease
www.nature.com/articles/s41...
Gene–environment interactions shape the host–microbial interface in inflammatory bowel disease
www.nature.com/articles/s41...
Thanks for highlighting our paper @lozanzi.bsky.social 🙏
#ToStressOrNotToStress! @christinviral.bsky.social @cadwelllab.bsky.social show @naturemicrobiol.nature.com that stress drives #interferon stimulated genes to protect against an enteric virus! After immune suppression by stress-induced glucorticoids, CD8 T cells get activated protecting the host!
Environmental stress drives clearance of a persistent enteric virus in mice - Nature Microbiology
Cage change of mice with persistent murine astrovirus infection triggers stress responses marked by corticosterone fluctuation, which is followed by CD8 T cell activation and induction of epithelial a...
www.nature.com
June 26, 2025 at 12:12 PM
Thanks for highlighting our paper @lozanzi.bsky.social 🙏
Reposted by Cadwell Lab
Reposted by Cadwell Lab
Chris Hunter @kingofpathogens.bsky.social and colleagues review parasite and host immune factors that impact the development of a mucosal vaccine for #Cryptosporidium : www.mucosalimmunology.org/article/S193...
May 28, 2025 at 2:53 PM
Chris Hunter @kingofpathogens.bsky.social and colleagues review parasite and host immune factors that impact the development of a mucosal vaccine for #Cryptosporidium : www.mucosalimmunology.org/article/S193...
Congratulations Xiaomin Yao and Eugene Rudensky for publishing this story @cp-immunity.bsky.social! Big thank you to NIH for making this work possible. Here’s a brief summary of this 🤯 finding about a gene variant that YOU 🫵 most likely have 1/n
kwnsfk27.r.eu-west-1.awstrack.me
May 17, 2025 at 10:25 PM
Congratulations Xiaomin Yao and Eugene Rudensky for publishing this story @cp-immunity.bsky.social! Big thank you to NIH for making this work possible. Here’s a brief summary of this 🤯 finding about a gene variant that YOU 🫵 most likely have 1/n
Reposted by Cadwell Lab
Congratulations to Susan Weiss (@PennMicro), Dennis Discher, Cherie Kagan (@pennengineering.bsky.social), Michael Jones-Correa & Sophia Rosenfeld (@PennSAS) on their election to the American Academy of Arts & Sciences! tinyurl.com/rtdecs92
May 12, 2025 at 7:18 PM
Congratulations to Susan Weiss (@PennMicro), Dennis Discher, Cherie Kagan (@pennengineering.bsky.social), Michael Jones-Correa & Sophia Rosenfeld (@PennSAS) on their election to the American Academy of Arts & Sciences! tinyurl.com/rtdecs92
Reposted by Cadwell Lab
Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.
April 10, 2025 at 1:38 PM
Your yearly reminder to acknowledge the core facilities you use and their staff scientists in your papers. These scientists are a crucial part of the scientific ecosystem and to continue to exist they need tangible credit for their work. Plus their associated expertise adds credibility to your work.
Reposted by Cadwell Lab
In other airborne news, here's a fabulous visual explanation of what measles does once it floats into your body. Gift link: www.nytimes.com/interactive/...
How Measles Attacks an Unvaccinated Child (Gift Article)
With falling vaccination rates and outbreaks that have caused more than 580 U.S. cases and at least one death, health experts expect hundreds or even thousands more to be infected in the coming months...
www.nytimes.com
April 5, 2025 at 7:41 PM
In other airborne news, here's a fabulous visual explanation of what measles does once it floats into your body. Gift link: www.nytimes.com/interactive/...
Reposted by Cadwell Lab
For those still interested in infection and the brain - here is a nice mix of math and pathogens - that tests the function of latency and how the immune system deals with a neuronal infection. Lots going on here to dissect - but turns out latency benefits host and parasite.
rdcu.be/efknc
rdcu.be/efknc
Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii
Nature Microbiology - In vivo and in silico analyses suggest that bradyzoite-directed immunity contributes to control of cyst numbers, tissue damage and mortality in mice.
rdcu.be
March 27, 2025 at 11:14 AM
For those still interested in infection and the brain - here is a nice mix of math and pathogens - that tests the function of latency and how the immune system deals with a neuronal infection. Lots going on here to dissect - but turns out latency benefits host and parasite.
rdcu.be/efknc
rdcu.be/efknc
Reposted by Cadwell Lab
What is up Bluesky!
I'm an Associate Editor working at #PLOSBiology with everything related with #Microbiology and #Immunology
Looking forward to all #science posts!
Also, if you wanna book a meet-the-editor zoom meeting with me and talk about your work, just click scheduler.zoom.us/melissa-vazq...!
I'm an Associate Editor working at #PLOSBiology with everything related with #Microbiology and #Immunology
Looking forward to all #science posts!
Also, if you wanna book a meet-the-editor zoom meeting with me and talk about your work, just click scheduler.zoom.us/melissa-vazq...!
Zoom Scheduler
Zoom external booking management
scheduler.zoom.us
March 24, 2025 at 6:35 PM
What is up Bluesky!
I'm an Associate Editor working at #PLOSBiology with everything related with #Microbiology and #Immunology
Looking forward to all #science posts!
Also, if you wanna book a meet-the-editor zoom meeting with me and talk about your work, just click scheduler.zoom.us/melissa-vazq...!
I'm an Associate Editor working at #PLOSBiology with everything related with #Microbiology and #Immunology
Looking forward to all #science posts!
Also, if you wanna book a meet-the-editor zoom meeting with me and talk about your work, just click scheduler.zoom.us/melissa-vazq...!
Reposted by Cadwell Lab
@cadwelllab.bsky.social has already posted about it, but we do have a new paper out about rewilding the immune system! This one is led by Ying-Han Chen (then NYU, now Academia Sinica) and Kimberly Zaldana (NYU), and it dives into the world of B cells.
www.science.org/doi/full/10....
www.science.org/doi/full/10....
Rewilding catalyzes maturation of the humoral immune system
Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.
www.science.org
March 16, 2025 at 8:37 PM
@cadwelllab.bsky.social has already posted about it, but we do have a new paper out about rewilding the immune system! This one is led by Ying-Han Chen (then NYU, now Academia Sinica) and Kimberly Zaldana (NYU), and it dives into the world of B cells.
www.science.org/doi/full/10....
www.science.org/doi/full/10....
Reposted by Cadwell Lab
There's more exciting work to come from the rewilding experiments, so please do stay tuned for work from @grahammunology.bsky.social @cadwelllab.bsky.social et al.
March 16, 2025 at 8:37 PM
There's more exciting work to come from the rewilding experiments, so please do stay tuned for work from @grahammunology.bsky.social @cadwelllab.bsky.social et al.
Reposted by Cadwell Lab
Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
First authors Madeline Churchill and Ankit Pandeya @nkeet50.bsky.social from @rauchlab.bsky.social show that tuft cells, known for their role in anti-parasite defenses, can also contribute to anti-bacterial responses in the small intestine. rupress.org/jem/article/...
#InfectiousDisease
#InfectiousDisease
March 13, 2025 at 4:31 PM
Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!
Congratulations Ying-Han Chen and Kim Zaldana for showing how B cells are altered when lab mice 🐭 are released outdoors! www.science.org/doi/10.1126/...
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Rewilding catalyzes maturation of the humoral immune system
Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.
www.science.org
March 8, 2025 at 2:40 PM
Congratulations Ying-Han Chen and Kim Zaldana for showing how B cells are altered when lab mice 🐭 are released outdoors! www.science.org/doi/10.1126/...
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Here’s some context for the paper followed by how gov’t 💰 + other sources combine to make these types of studies possible 1/n
Reposted by Cadwell Lab
1/2 New publication from the lab from the talented postdoc Dr. Andy Perrault in collaboration with Dr. Alejandro Pironti! pubmed.ncbi.nlm.nih.gov/39977318/
Enterobacter hormaechei replaces virulence with carbapenem resistance via porin loss - PubMed
Pathogenic <i>Enterobacter</i> species are of increasing clinical concern due to the multidrug-resistant nature of these bacteria, including resistance to carbapenem antibiotics. Our understanding of ...
pubmed.ncbi.nlm.nih.gov
February 22, 2025 at 3:42 PM
1/2 New publication from the lab from the talented postdoc Dr. Andy Perrault in collaboration with Dr. Alejandro Pironti! pubmed.ncbi.nlm.nih.gov/39977318/
Reposted by Cadwell Lab
Congratulations Yasmine!! Fantastic news and well deserved!
🎖️ Proud of our Managing Director, Yasmine Belkaid, named Chevalier de la Légion d'Honneur!
A well-deserved honor for her pioneering work in immunology, microbiota & nutrition.
Her research embodies the Pasteurian spirit of science for humanity! 👏 #Science #Immunology
A well-deserved honor for her pioneering work in immunology, microbiota & nutrition.
Her research embodies the Pasteurian spirit of science for humanity! 👏 #Science #Immunology
February 14, 2025 at 12:10 PM
Congratulations Yasmine!! Fantastic news and well deserved!
Reposted by Cadwell Lab
Petition to Reverse the NIH Indirect Cost Cap initiated by Tom Maniatis. Please amplify
Sign the Petition: chng.it/kK2HMP5pGk
"Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."
Sign the Petition: chng.it/kK2HMP5pGk
"Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."
Sign the Petition
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
chng.it
February 10, 2025 at 5:49 PM
Petition to Reverse the NIH Indirect Cost Cap initiated by Tom Maniatis. Please amplify
Sign the Petition: chng.it/kK2HMP5pGk
"Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."
Sign the Petition: chng.it/kK2HMP5pGk
"Share with Leadership & Faculty. Reach out to professional societies, biotech and pharma leaders, and philanthropic organizations to raise awareness and mobilize support."
Reposted by Cadwell Lab
@solvingforsci.bsky.social (@maxkrummel.bsky.social and others)came up with an alternative (I think, transformative) peer-review system (still in its pilot phase). Contribute by submitting (or reviewing) @biorxiv-immuno.bsky.social studies to solvingfor.org/discovery-st...
solvingfor.org
February 2, 2025 at 5:45 PM
@solvingforsci.bsky.social (@maxkrummel.bsky.social and others)came up with an alternative (I think, transformative) peer-review system (still in its pilot phase). Contribute by submitting (or reviewing) @biorxiv-immuno.bsky.social studies to solvingfor.org/discovery-st...
Reposted by Cadwell Lab
Fundamental research led to the discovery of #Remicade, the first biologic drug that has saved millions of people from suffering. The Vilceks have channeled their fortunes into supporting #immigrants. Please check out various opps on the website!
⭐️ Hello, @bsky.app! For those of us who don't know us: The Vilcek Foundation was founded by Jan and Marica Vilcek in the year 2000 to raise awareness of immigrant contributions in the U.S., and to foster appreciation for the arts and sciences. #Nonprofit #Philanthropy #Immigrants #Arts #NYC
The Vilcek Foundation: Origins & Establishment
YouTube video by The Vilcek Foundation
www.youtube.com
December 31, 2024 at 10:35 AM
Fundamental research led to the discovery of #Remicade, the first biologic drug that has saved millions of people from suffering. The Vilceks have channeled their fortunes into supporting #immigrants. Please check out various opps on the website!
Reposted by Cadwell Lab
We're hiring! Funded postdoctoral position available in the Moltke Lab. 79k starting salary and access to a fellowship program in the Institute for Translational Immunology that offers both academic and industry training tracks. Details here: jobrxiv.org/job/universi...
Postdoctoral Fellow - Moltke Lab
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
jobrxiv.org
December 17, 2024 at 11:58 PM
We're hiring! Funded postdoctoral position available in the Moltke Lab. 79k starting salary and access to a fellowship program in the Institute for Translational Immunology that offers both academic and industry training tracks. Details here: jobrxiv.org/job/universi...
Reposted by Cadwell Lab
Recently finished your PhD or plan to in early 2025 and love #Tcell biology, particularly #gdTcells? We're recruiting a #NIDDK-funded #postdoc @sinaiimmuno.bsky.social! We'd love to have an #immunologist with expertise in #GIsky or #IBDsky join our team. bit.ly/4izpZLj #Immunosky
Postdoctoral Fellow-MSH-20093-049 in New York, NY | Mount Sinai Health Systems
Mount Sinai is hiring a Postdoctoral Fellow-MSH-20093-049 in New York, NY. Review all of the job details and apply today!
bit.ly
December 17, 2024 at 9:17 PM
Recently finished your PhD or plan to in early 2025 and love #Tcell biology, particularly #gdTcells? We're recruiting a #NIDDK-funded #postdoc @sinaiimmuno.bsky.social! We'd love to have an #immunologist with expertise in #GIsky or #IBDsky join our team. bit.ly/4izpZLj #Immunosky
Reposted by Cadwell Lab
I'm very happy to note that the @plosbiology.org journal Bluesky account is now active. Do follow it if you'd like to hear about the exciting research and comment that we publish!
December 16, 2024 at 5:43 PM
I'm very happy to note that the @plosbiology.org journal Bluesky account is now active. Do follow it if you'd like to hear about the exciting research and comment that we publish!