Juan Fuxman Bass
@fuxmanlab.bsky.social
Associate professor at Boston University | systems biology, gene regulation, viral gene expression 🏳️🌈🇦🇷
It’s been a pleasure to organize the Rules of Protein-DNA Recognition meeting in Cancun. Spectacular talks and an amazing and supportive scientific community!
October 17, 2025 at 12:14 PM
It’s been a pleasure to organize the Rules of Protein-DNA Recognition meeting in Cancun. Spectacular talks and an amazing and supportive scientific community!
This is big!
Excited to share my postdoc work, out on bioRxiv today! Histones package DNA into nucleosomes to form the building blocks of chromatin, but how modular and programmable is this system? 1/9
September 11, 2025 at 8:02 PM
This is big!
Excited to share this collaborative review with @dsegre.bsky.social and @devmoy.bsky.social. We discuss common issues with context-specific genome-scale metabolic network models and provide recommendation for future model development.
Just published @cp-trendsbiotech: Flux sampling and context-specific genome-scale metabolic models for biotechnological applications: www.cell.com/trends/biote... by @devmoy, with @fuxmanlab
Flux sampling and context-specific genome-scale metabolic models for biotechnological applications
Genome-scale metabolic models are used in fields ranging from metabolic engineering
to drug discovery and microbiome design. Although these models are often used to predict
putatively optimal states, ...
www.cell.com
August 8, 2025 at 11:04 AM
Excited to share this collaborative review with @dsegre.bsky.social and @devmoy.bsky.social. We discuss common issues with context-specific genome-scale metabolic network models and provide recommendation for future model development.
Exited to share our recent work on viral cis-regulatory elements in collaboration with @tewhey.bsky.social!
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
July 24, 2025 at 7:18 PM
Exited to share our recent work on viral cis-regulatory elements in collaboration with @tewhey.bsky.social!
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
Reposted by Juan Fuxman Bass
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
April 28, 2025 at 5:20 PM
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Exited to share our recent work on TF isoforms! Amazing work by @kaiamattioli.bsky.social Luke Lambourne and Clarissa Santoso and many other collaborators.
our work on the molecular differences between transcription factor isoforms is out now in Molecular Cell!
key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity
many are "negative regulators" & misexpressed in cancer
www.sciencedirect.com/science/arti...
key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity
many are "negative regulators" & misexpressed in cancer
www.sciencedirect.com/science/arti...
March 26, 2025 at 5:37 PM
Exited to share our recent work on TF isoforms! Amazing work by @kaiamattioli.bsky.social Luke Lambourne and Clarissa Santoso and many other collaborators.
Reposted by Juan Fuxman Bass
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
March 22, 2025 at 10:44 AM
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
Reposted by Juan Fuxman Bass
Scientists are unfairly and devastatingly seeing their grants cut and careers thrown into uncertainty, yet are still working 24/7 to continue their research, treat patients, talk to journalists, advocate with elected officials, and keep the public informed about potential threats. Absolute heroes!
March 18, 2025 at 8:50 PM
Scientists are unfairly and devastatingly seeing their grants cut and careers thrown into uncertainty, yet are still working 24/7 to continue their research, treat patients, talk to journalists, advocate with elected officials, and keep the public informed about potential threats. Absolute heroes!
Reposted by Juan Fuxman Bass
There are days in life that shake you.
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
March 18, 2025 at 11:27 PM
There are days in life that shake you.
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵
Reposted by Juan Fuxman Bass
Scientists have just cured pancreatic cancer in some patients with personalized mRNA vaccines. Pancreatic cancer. And this Trump administration wants to throw it all away.
They’re throwing away a cure for cancer.
They’re throwing away a cure for cancer.
Exclusive: NIH officials have advised scientists to remove reference to mRNA vaccines from their grant applications, in expectation the Trump administration intends to abandon most research in the field.
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News
Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...
kffhealthnews.org
March 17, 2025 at 1:16 AM
Scientists have just cured pancreatic cancer in some patients with personalized mRNA vaccines. Pancreatic cancer. And this Trump administration wants to throw it all away.
They’re throwing away a cure for cancer.
They’re throwing away a cure for cancer.
Reposted by Juan Fuxman Bass
This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH
March 15, 2025 at 5:32 PM
This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH
Reposted by Juan Fuxman Bass
The Stand Up For Science protests have kicked off worldwide. Thousands of scientists demonstrated in solidarity with their US counterparts across France to defend the scientific community. (📹 @Margot_Brunet_)
#3E #FranceProtests #USprotests #March7Science #StandUpForScience #Mar7
#3E #FranceProtests #USprotests #March7Science #StandUpForScience #Mar7
March 7, 2025 at 6:02 PM
The Stand Up For Science protests have kicked off worldwide. Thousands of scientists demonstrated in solidarity with their US counterparts across France to defend the scientific community. (📹 @Margot_Brunet_)
#3E #FranceProtests #USprotests #March7Science #StandUpForScience #Mar7
#3E #FranceProtests #USprotests #March7Science #StandUpForScience #Mar7
Reposted by Juan Fuxman Bass
✊Massive turnout for STAND UP FOR SCIENCE rally in Boston #StandUpForScience
March 7, 2025 at 7:45 PM
✊Massive turnout for STAND UP FOR SCIENCE rally in Boston #StandUpForScience
Standing up for science in Boston!
March 7, 2025 at 7:02 PM
Standing up for science in Boston!
Reposted by Juan Fuxman Bass
WHERE WILL YOU BE ON MARCH 7TH!?
Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!
#standupforscience2025
Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!
#standupforscience2025
March 2, 2025 at 2:04 AM
WHERE WILL YOU BE ON MARCH 7TH!?
Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!
#standupforscience2025
Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!
#standupforscience2025
Reposted by Juan Fuxman Bass
We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country.
This Friday, where will you be?
standupforscience2025.org
This Friday, where will you be?
standupforscience2025.org
March 2, 2025 at 4:27 PM
We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country.
This Friday, where will you be?
standupforscience2025.org
This Friday, where will you be?
standupforscience2025.org
Reposted by Juan Fuxman Bass
This framing is their framing, and NYT took the bait. The correct and accurate framing is: “Deep cuts to medical research threatens progress on cancer and heart disease research, costs the economy $80B, and threatens 300,000 jobs across red and blue states”
February 8, 2025 at 7:17 PM
This framing is their framing, and NYT took the bait. The correct and accurate framing is: “Deep cuts to medical research threatens progress on cancer and heart disease research, costs the economy $80B, and threatens 300,000 jobs across red and blue states”
Reposted by Juan Fuxman Bass
Trump & Musk are making massive cuts to the National Institutes of Health.
I know there is a lot going on right now, but this is one of worst things they have done so far, will affect cancer research and trials, the search for cures, innovation and competitiveness, our universities. Your lives.
I know there is a lot going on right now, but this is one of worst things they have done so far, will affect cancer research and trials, the search for cures, innovation and competitiveness, our universities. Your lives.
February 8, 2025 at 11:16 PM
Trump & Musk are making massive cuts to the National Institutes of Health.
I know there is a lot going on right now, but this is one of worst things they have done so far, will affect cancer research and trials, the search for cures, innovation and competitiveness, our universities. Your lives.
I know there is a lot going on right now, but this is one of worst things they have done so far, will affect cancer research and trials, the search for cures, innovation and competitiveness, our universities. Your lives.
Reposted by Juan Fuxman Bass
In North Carolina
NIH FUNDING:
$2.28B
JOBS SUPPORTED:
25,081
ECONOMIC ACTIVITY SUPPORTED:
$5.39B
NIH FUNDING:
$2.28B
JOBS SUPPORTED:
25,081
ECONOMIC ACTIVITY SUPPORTED:
$5.39B
In PA:
NIH FUNDING:
$2.23B
JOBS SUPPORTED:
21,784
ECONOMIC ACTIVITY SUPPORTED:
$5.23B
NIH FUNDING:
$2.23B
JOBS SUPPORTED:
21,784
ECONOMIC ACTIVITY SUPPORTED:
$5.23B
In Connecticut -
NIH FUNDING:
$770M
JOBS SUPPORTED:
6609
ECONOMIC ACTIVITY SUPPORTED:
$1.68B
NIH FUNDING:
$770M
JOBS SUPPORTED:
6609
ECONOMIC ACTIVITY SUPPORTED:
$1.68B
February 9, 2025 at 1:49 AM
In North Carolina
NIH FUNDING:
$2.28B
JOBS SUPPORTED:
25,081
ECONOMIC ACTIVITY SUPPORTED:
$5.39B
NIH FUNDING:
$2.28B
JOBS SUPPORTED:
25,081
ECONOMIC ACTIVITY SUPPORTED:
$5.39B
Reposted by Juan Fuxman Bass
NIH doesn’t just support infectious disease research—it drives breakthroughs in cancer, childhood diseases, heart disease, diabetes & more.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
February 8, 2025 at 3:07 PM
NIH doesn’t just support infectious disease research—it drives breakthroughs in cancer, childhood diseases, heart disease, diabetes & more.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
Thanks to NIH, we have:
💉 Cancer immunotherapy
❤️ Cholesterol-lowering statins
🩸 Insulin for diabetes
Investing in NIH = investing in life-saving discoveries.
Reposted by Juan Fuxman Bass
NIH cuts billions of dollars in biomedical funding, effective immediately. The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease. www.washingtonpost.com/health/2025/...
NIH cuts billions of dollars in biomedical funding, effective immediately
The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.
www.washingtonpost.com
February 8, 2025 at 4:15 PM
NIH cuts billions of dollars in biomedical funding, effective immediately. The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease. www.washingtonpost.com/health/2025/...
Congratulations Devlin Moyer for a wonderful thesis defense! Can’t wait to see what you’ll do next.
December 18, 2024 at 7:26 AM
Congratulations Devlin Moyer for a wonderful thesis defense! Can’t wait to see what you’ll do next.
Hello Bluesky! The Fuxman Bass lab is very excited to join this growing 🦋community. We look forward to sharing our work and to connect with other scientists!
November 27, 2024 at 5:44 AM
Hello Bluesky! The Fuxman Bass lab is very excited to join this growing 🦋community. We look forward to sharing our work and to connect with other scientists!