George
@godette.bsky.social
George, a computational and molecular biologist.
Making others learn and appreciate science and how it is done. YouTube: https://youtube.com/@gmeds25
Making others learn and appreciate science and how it is done. YouTube: https://youtube.com/@gmeds25
Reposted by George
⚡⚡Excited to announce I'll be starting my lab at the Max Planck Institute of Molecular Genetics (@molgen.mpg.de) in Berlin in December! Leaving sunny California to join a fantastic environment with colleagues who do super cool work.
🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab
🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab
October 6, 2025 at 1:46 PM
⚡⚡Excited to announce I'll be starting my lab at the Max Planck Institute of Molecular Genetics (@molgen.mpg.de) in Berlin in December! Leaving sunny California to join a fantastic environment with colleagues who do super cool work.
🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab
🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab
Reposted by George
New paper by our Plaschka lab with Brennecke’s lab at IMBA!
Researchers at the Vienna BioCenter have solved a 20-year-old mystery in genome biology, revealing how PIWI proteins engage partner molecules to silence “jumping genes” that threaten genetic stability.
Researchers at the Vienna BioCenter have solved a 20-year-old mystery in genome biology, revealing how PIWI proteins engage partner molecules to silence “jumping genes” that threaten genetic stability.
How cells lock down “jumping genes”:
Researchers from IMBA and IMP identify the first protein interactions that trigger PIWI–piRNA–mediated transposon silencing, using AlphaFold predictions, genetics, biochemistry and cell biology.
Read more: www.viennabiocenter.org/about/news/t...
Researchers from IMBA and IMP identify the first protein interactions that trigger PIWI–piRNA–mediated transposon silencing, using AlphaFold predictions, genetics, biochemistry and cell biology.
Read more: www.viennabiocenter.org/about/news/t...
September 8, 2025 at 9:10 AM
New paper by our Plaschka lab with Brennecke’s lab at IMBA!
Researchers at the Vienna BioCenter have solved a 20-year-old mystery in genome biology, revealing how PIWI proteins engage partner molecules to silence “jumping genes” that threaten genetic stability.
Researchers at the Vienna BioCenter have solved a 20-year-old mystery in genome biology, revealing how PIWI proteins engage partner molecules to silence “jumping genes” that threaten genetic stability.
Reposted by George
🚀 Registration is open for BioHackathon Germany 2025! Join us 1–5 Dec in Walsrode for hands-on projects, networking, and innovation in #bioinformatics. 🧬🤝
🏨 Anders Hotel Walsrode | 🍽️ Social events | ✈️ Easy travel
🔗 Seats limited—register now! www.denbi.de/de-nbi-event...
#Hackathon
🏨 Anders Hotel Walsrode | 🍽️ Social events | ✈️ Easy travel
🔗 Seats limited—register now! www.denbi.de/de-nbi-event...
#Hackathon
September 3, 2025 at 8:55 AM
🚀 Registration is open for BioHackathon Germany 2025! Join us 1–5 Dec in Walsrode for hands-on projects, networking, and innovation in #bioinformatics. 🧬🤝
🏨 Anders Hotel Walsrode | 🍽️ Social events | ✈️ Easy travel
🔗 Seats limited—register now! www.denbi.de/de-nbi-event...
#Hackathon
🏨 Anders Hotel Walsrode | 🍽️ Social events | ✈️ Easy travel
🔗 Seats limited—register now! www.denbi.de/de-nbi-event...
#Hackathon
Reposted by George
Enroll in our Online Course Modeling of Infectious Diseases! 🌐🦠
👉 www.fun-mooc.fr/en/courses/m...
In this online MOOC, you'll gain a solid foundation in mathematical modeling with a comprehensive approach to understanding the dynamics of infectious diseases.
👉 www.fun-mooc.fr/en/courses/m...
In this online MOOC, you'll gain a solid foundation in mathematical modeling with a comprehensive approach to understanding the dynamics of infectious diseases.
September 2, 2025 at 9:10 AM
Enroll in our Online Course Modeling of Infectious Diseases! 🌐🦠
👉 www.fun-mooc.fr/en/courses/m...
In this online MOOC, you'll gain a solid foundation in mathematical modeling with a comprehensive approach to understanding the dynamics of infectious diseases.
👉 www.fun-mooc.fr/en/courses/m...
In this online MOOC, you'll gain a solid foundation in mathematical modeling with a comprehensive approach to understanding the dynamics of infectious diseases.
Reposted by George
A new review on the challenges of identifying cancer cells in single-cell data, summarizing current computational solutions as well as underexplored features of malignancy. From scientists @sib.swiss
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Identification of malignant cells in single-cell transcriptomics data - Communications Biology
This review article discusses the challenges of identifying cancer cells in single-cell data, summarizing current computational solutions as well as underexplored features of malignancy.
www.nature.com
August 25, 2025 at 7:47 PM
A new review on the challenges of identifying cancer cells in single-cell data, summarizing current computational solutions as well as underexplored features of malignancy. From scientists @sib.swiss
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by George
Next @denbi.bsky.social #training course in collaboration with @biont-training.bsky.social: 🖥️🔧 Dive into “System Administration for HPC” – a 3-day online workshop, Oct 21–23!
Perfect for junior sysadmins or Linux users aiming for #HPC!
Register here: www.denbi.de/training-cou... 🚀🔗
Perfect for junior sysadmins or Linux users aiming for #HPC!
Register here: www.denbi.de/training-cou... 🚀🔗
August 20, 2025 at 10:51 AM
Next @denbi.bsky.social #training course in collaboration with @biont-training.bsky.social: 🖥️🔧 Dive into “System Administration for HPC” – a 3-day online workshop, Oct 21–23!
Perfect for junior sysadmins or Linux users aiming for #HPC!
Register here: www.denbi.de/training-cou... 🚀🔗
Perfect for junior sysadmins or Linux users aiming for #HPC!
Register here: www.denbi.de/training-cou... 🚀🔗
Reposted by George
🍹@martenslab.bsky.social @elias-adriaenssens.bsky.social & co show that, unlike soluble, transmembrane cargo receptors initiate autophagosome biogenesis by recruiting the FIP200/ULK1 or WIPI–ATG13 complex, revealing unexpected flexibility in the selective #autophagy machinery.
bit.ly/4lpGh9P
bit.ly/4lpGh9P
Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery - Nature Cell Biology
Adriaenssens et al. show that unlike soluble cargo receptors, transmembrane cargo receptors initiate autophagosome biogenesis by recruiting the FIP200/ULK1 or WIPI–ATG13 complex, revealing unexpected ...
bit.ly
August 14, 2025 at 8:07 PM
🍹@martenslab.bsky.social @elias-adriaenssens.bsky.social & co show that, unlike soluble, transmembrane cargo receptors initiate autophagosome biogenesis by recruiting the FIP200/ULK1 or WIPI–ATG13 complex, revealing unexpected flexibility in the selective #autophagy machinery.
bit.ly/4lpGh9P
bit.ly/4lpGh9P
🔗 Snakemake for Bioinformatics – Playlist
👉 youtube.com/playlist?lis...
Been putting together a simple series on bioinformatics workflows using Bash & Snakemake. Fairly beginner-friendly.
Try it out.
#Snakemake #Bioinformatics #BashScripting #ReproducibleScience #BioinformaticsForBeginners
👉 youtube.com/playlist?lis...
Been putting together a simple series on bioinformatics workflows using Bash & Snakemake. Fairly beginner-friendly.
Try it out.
#Snakemake #Bioinformatics #BashScripting #ReproducibleScience #BioinformaticsForBeginners
Snakemake for Bioinformatics - YouTube
Here is a playlist to get you started with Snakemake for Bioinformatics. These are beginner-friendly tutorials regardless of whether you are just starting ou...
youtube.com
July 18, 2025 at 2:59 AM
🔗 Snakemake for Bioinformatics – Playlist
👉 youtube.com/playlist?lis...
Been putting together a simple series on bioinformatics workflows using Bash & Snakemake. Fairly beginner-friendly.
Try it out.
#Snakemake #Bioinformatics #BashScripting #ReproducibleScience #BioinformaticsForBeginners
👉 youtube.com/playlist?lis...
Been putting together a simple series on bioinformatics workflows using Bash & Snakemake. Fairly beginner-friendly.
Try it out.
#Snakemake #Bioinformatics #BashScripting #ReproducibleScience #BioinformaticsForBeginners
Reposted by George
SFTSV is a deadly tick-borne virus. In this study, Petit et al. used a multi-omics approach to reveal antiviral responses in SFTSV-infected tick cells
@virotick.bsky.social @brennanlab.bsky.social @cvrinfo.bsky.social
@uniofsurrey.bsky.social
@virotick.bsky.social @brennanlab.bsky.social @cvrinfo.bsky.social
@uniofsurrey.bsky.social
Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors - Nature Communications
Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) is a deadly tick-borne virus and a growing global health threat. In this study, Petit et al. used a multi-omics approach on SFTSV-infected tick cells to study its impact and reveal host antiviral responses and key restriction factors.
bit.ly
July 14, 2025 at 7:06 PM
SFTSV is a deadly tick-borne virus. In this study, Petit et al. used a multi-omics approach to reveal antiviral responses in SFTSV-infected tick cells
@virotick.bsky.social @brennanlab.bsky.social @cvrinfo.bsky.social
@uniofsurrey.bsky.social
@virotick.bsky.social @brennanlab.bsky.social @cvrinfo.bsky.social
@uniofsurrey.bsky.social
Reposted by George
In @jem.org, Yang, Yan at al. describe an inducible Ngly1 knockout mouse model, iNgly1−/−, that reveals pronounced loss of Purkinje cells in the cerebellum without neuroinflammation. Sting1 knockout or STING inhibitor VS-X4 significantly rescues iNgly1−/− disease in mice. rupress.org/jem/article/...
July 14, 2025 at 4:17 PM
In @jem.org, Yang, Yan at al. describe an inducible Ngly1 knockout mouse model, iNgly1−/−, that reveals pronounced loss of Purkinje cells in the cerebellum without neuroinflammation. Sting1 knockout or STING inhibitor VS-X4 significantly rescues iNgly1−/− disease in mice. rupress.org/jem/article/...
Reposted by George
Finally out @natcomms.nature.com
"Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses".
Great collab between @savvideslab.bsky.social (we performed #CryoEM) and Xavier Saelens Lab, spearheaded by Arne Matthys.
www.nature.com/articles/s41...
"Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses".
Great collab between @savvideslab.bsky.social (we performed #CryoEM) and Xavier Saelens Lab, spearheaded by Arne Matthys.
www.nature.com/articles/s41...
July 10, 2025 at 8:45 AM
Finally out @natcomms.nature.com
"Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses".
Great collab between @savvideslab.bsky.social (we performed #CryoEM) and Xavier Saelens Lab, spearheaded by Arne Matthys.
www.nature.com/articles/s41...
"Single-domain antibodies directed against hemagglutinin and neuraminidase protect against influenza B viruses".
Great collab between @savvideslab.bsky.social (we performed #CryoEM) and Xavier Saelens Lab, spearheaded by Arne Matthys.
www.nature.com/articles/s41...
Reposted by George
What next after RNA-Sequencing? Do a drug screen. Check my step-by-step tutorial here youtu.be/BH69_aVQe-M?...
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
Bioinformatics drug screen
YouTube video by GMeds
youtu.be
July 7, 2025 at 3:03 PM
What next after RNA-Sequencing? Do a drug screen. Check my step-by-step tutorial here youtu.be/BH69_aVQe-M?...
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
What next after RNA-Sequencing? Do a drug screen. Check my step-by-step tutorial here youtu.be/BH69_aVQe-M?...
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
Bioinformatics drug screen
YouTube video by GMeds
youtu.be
July 7, 2025 at 3:03 PM
What next after RNA-Sequencing? Do a drug screen. Check my step-by-step tutorial here youtu.be/BH69_aVQe-M?...
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
Prefer reading? Here's a medium for you medium.com/@odettegeorg...
#Bioinformatics #DrugDiscovery #RNASequencing #DataScience #Genomics #PrecisionMedicine #Biotech #ComputationalBiology
New on YouTube: Snakemake for Bioinformatics Engineering & Data Analysis
Build reproducible workflows from scratch.
▶️ youtube.com/playlist?lis...
I am making this beginner-friendly, whether you're new to Snakemake or bioinformatics.
#Snakemake #Bioinformatics #DataAnalysis #Genomics
Build reproducible workflows from scratch.
▶️ youtube.com/playlist?lis...
I am making this beginner-friendly, whether you're new to Snakemake or bioinformatics.
#Snakemake #Bioinformatics #DataAnalysis #Genomics
Snakemake for Bioinformatics - YouTube
Here is a playlist to get you started with Snakemake for Bioinformatics. These are beginner-friendly tutorials regardless of whether you are just starting ou...
youtube.com
July 5, 2025 at 8:39 PM
New on YouTube: Snakemake for Bioinformatics Engineering & Data Analysis
Build reproducible workflows from scratch.
▶️ youtube.com/playlist?lis...
I am making this beginner-friendly, whether you're new to Snakemake or bioinformatics.
#Snakemake #Bioinformatics #DataAnalysis #Genomics
Build reproducible workflows from scratch.
▶️ youtube.com/playlist?lis...
I am making this beginner-friendly, whether you're new to Snakemake or bioinformatics.
#Snakemake #Bioinformatics #DataAnalysis #Genomics
Reposted by George
Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included.
training.institut-curie.org/courses/deve...
training.institut-curie.org/courses/deve...
June 13, 2025 at 4:55 PM
Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included.
training.institut-curie.org/courses/deve...
training.institut-curie.org/courses/deve...
Reposted by George
Are you looking for homologous sequences but alignments do not seem to work? SHARK is available as a webserver: compare sequences or search against precomputed IDR datasets: bio-shark.org @narjournal.bsky.social @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
SHARK: web server for alignment-free homology assessment for intrinsically disordered and unalignable protein regions
Abstract. Whereas alignment has been fundamental to sequence-based assessments of protein homology, it is ineffective for intrinsically disordered regions
doi.org
May 28, 2025 at 9:24 PM
Are you looking for homologous sequences but alignments do not seem to work? SHARK is available as a webserver: compare sequences or search against precomputed IDR datasets: bio-shark.org @narjournal.bsky.social @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
Reposted by George
Our team is going to answer student questions about our PhD program on 3 April! Sign up here
ow.ly/ptFT50PNJV2
@univie.ac.at @impvienna.bsky.social @imbavienna.bsky.social @gmivienna.bsky.social @maxperutzlabs.bsky.social @viennabiocenter.bsky.social
ow.ly/ptFT50PNJV2
@univie.ac.at @impvienna.bsky.social @imbavienna.bsky.social @gmivienna.bsky.social @maxperutzlabs.bsky.social @viennabiocenter.bsky.social
April 2, 2025 at 11:33 AM
Our team is going to answer student questions about our PhD program on 3 April! Sign up here
ow.ly/ptFT50PNJV2
@univie.ac.at @impvienna.bsky.social @imbavienna.bsky.social @gmivienna.bsky.social @maxperutzlabs.bsky.social @viennabiocenter.bsky.social
ow.ly/ptFT50PNJV2
@univie.ac.at @impvienna.bsky.social @imbavienna.bsky.social @gmivienna.bsky.social @maxperutzlabs.bsky.social @viennabiocenter.bsky.social
Reposted by George
Announcing Evo 2: The largest publicly available, AI model for biology to date, capable of understanding and designing genetic code across all three domains of life. t.co/1Zt6gQ74SA
February 19, 2025 at 4:31 PM
Announcing Evo 2: The largest publicly available, AI model for biology to date, capable of understanding and designing genetic code across all three domains of life. t.co/1Zt6gQ74SA
Reposted by George
Our Opening Doors Internship Programme is open for applications!
With 15 roles available in the UK, US, Germany, China, and the Netherlands this year’s programme is more global than ever. #BePartOfProgress with us and explore the available positions: http://spklr.io/633202uyj
With 15 roles available in the UK, US, Germany, China, and the Netherlands this year’s programme is more global than ever. #BePartOfProgress with us and explore the available positions: http://spklr.io/633202uyj
February 13, 2025 at 2:30 PM
Our Opening Doors Internship Programme is open for applications!
With 15 roles available in the UK, US, Germany, China, and the Netherlands this year’s programme is more global than ever. #BePartOfProgress with us and explore the available positions: http://spklr.io/633202uyj
With 15 roles available in the UK, US, Germany, China, and the Netherlands this year’s programme is more global than ever. #BePartOfProgress with us and explore the available positions: http://spklr.io/633202uyj
Reposted by George
E2A SUMOylation promotes HAdV mediated inhibition of the tumor suppressor p53 during infection https://www.biorxiv.org/content/10.1101/2025.02.07.636424v1
February 8, 2025 at 1:32 PM
E2A SUMOylation promotes HAdV mediated inhibition of the tumor suppressor p53 during infection https://www.biorxiv.org/content/10.1101/2025.02.07.636424v1
Reposted by George
We have extended the deadline until Feb. 14th. Take the opportunity, funding support is avaliable! 🐸⚠️
meetings.cshl.edu/courses.aspx...
meetings.cshl.edu/courses.aspx...
February 5, 2025 at 8:51 PM
We have extended the deadline until Feb. 14th. Take the opportunity, funding support is avaliable! 🐸⚠️
meetings.cshl.edu/courses.aspx...
meetings.cshl.edu/courses.aspx...
Reposted by George
Our cell line of the week is TRF2 - illuminating the telomeres! 🧪
Our stem cell lines and plasmids are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social and @addgene.bsky.social
#CellLineOfTheWeek #FluorescenceFriday
Our stem cell lines and plasmids are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social and @addgene.bsky.social
#CellLineOfTheWeek #FluorescenceFriday
February 7, 2025 at 8:46 PM
Our cell line of the week is TRF2 - illuminating the telomeres! 🧪
Our stem cell lines and plasmids are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social and @addgene.bsky.social
#CellLineOfTheWeek #FluorescenceFriday
Our stem cell lines and plasmids are available for just the cost of shipping to support scientific discovery.
📦 Distributed by @coriellinstitute.bsky.social and @addgene.bsky.social
#CellLineOfTheWeek #FluorescenceFriday
Reposted by George
📌 Applications open on February 25 via the MonMaster platform.
📧 Contact us: [email protected]
🌐 More info: qbio.umontpellier.fr
📧 Contact us: [email protected]
🌐 More info: qbio.umontpellier.fr
February 4, 2025 at 9:10 AM
📌 Applications open on February 25 via the MonMaster platform.
📧 Contact us: [email protected]
🌐 More info: qbio.umontpellier.fr
📧 Contact us: [email protected]
🌐 More info: qbio.umontpellier.fr
Reposted by George
Sad to hear that Scott Hawley passed away. He was an amazing educator and enthusiastic scientist. Together with Michael Ashburner they led the Drosophila @cshlnews.bsky.social course which changed my scientific life. I am sure that up there they now discuss variegation and non-disjunction mechanisms
February 1, 2025 at 8:00 PM
Sad to hear that Scott Hawley passed away. He was an amazing educator and enthusiastic scientist. Together with Michael Ashburner they led the Drosophila @cshlnews.bsky.social course which changed my scientific life. I am sure that up there they now discuss variegation and non-disjunction mechanisms
Reposted by George
PRMT1-mediated stabilization of EGR1 promotes sepsis-induced acute lung injury (ALI) via GLS2, highlighting the therapeutic potential of targeting PRMT1 or EGR1 in the treatment of sepsis-induced ALI.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Arginine methyltransferase PRMT1 promotes ferroptosis through EGR1/GLS2 axis in sepsis-related acute lung injury - Communications Biology
PRMT1-mediated stabilization of EGR1 promotes sepsis-induced acute lung injury (ALI) via GLS2, highlighting the therapeutic potential of targeting PRMT1 or EGR1 in the treatment of sepsis-induced ALI.
www.nature.com
February 4, 2025 at 9:15 AM
PRMT1-mediated stabilization of EGR1 promotes sepsis-induced acute lung injury (ALI) via GLS2, highlighting the therapeutic potential of targeting PRMT1 or EGR1 in the treatment of sepsis-induced ALI.
www.nature.com/articles/s42...
www.nature.com/articles/s42...