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Reposted by James Wilson, DO, FACP, FAWM, CTropMed

TRAstonDrs @castltrastondrs.bsky.social · 7d

#Medsky🧪 #IDsky #immunosky #oncosky #publichealth While not a classic #oncogenicvirus, #SARSCoV2 might fuel #lungcancer through multiple indirect mechanisms, creating a pro-tumorigenic environment in t🫁 .

Dr David Joffe MB BS(Hons), PhD, FRACP @davidjoffe64.bsky.social · 8d

The double-edged sword: How SARS-CoV-2 might fuel lung cancer:
Investigating the potential oncogenic mechanisms of the novel coronavirus
in lung carcinogenesis

doi.org/10.1016/j.ma...

Redirecting

doi.org

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · 7d

Vibrio, Toxo, HAV, Norovirus.
Anything that can contaminate water ways and then build up in bivalves and reproduce can cause outbreaks… mussels and oysters… they just drink up the salt water nutrients, poop and all ;)

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Reposted by James Wilson, DO, FACP, FAWM, CTropMed

Pharmageddon @pharmageddon.bsky.social · 7d

Next draft Infection Card for Epipocalypse: Bug Detectives: Nocardia!

One of my favs. Doesn't get enough love. The other group of organisms causing chronic CNS + pulmonary syndromes besides TB and fungi.

#IDSky #MedSky #EpiSky any feedback or suggestions?

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Reposted by James Wilson, DO, FACP, FAWM, CTropMed

Contagion® @contagionlive.bsky.social · 9d

The Centers for Disease Control and Prevention (CDC) provided more information on a multistate outbreak and genomic testing. #IDsky #Medsky

Listeria Outbreak Update: 3 More Illnesses and 1 Death Linked to Packaged Meals

The Centers for Disease Control and Prevention (CDC) provided more information on a multistate outbreak and genomic testing.

www.contagionlive.com

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · 9d

@accpchest.bsky.social this is going to be addressed soon, right? I mean, it’s October now..?
#accp #chest #abimexams #boardprep

James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Sep 3

www.instagram.com/reel/DOJdAFk...
God…. Thank you for @glaucomflecken.bsky.social
Every IM & ICU rounds with nephrology and every time someone ordered urine chemistries and serum osmolalities…
Did it change your clinical management…? Did it? DID IT, ABIM EXAM?
#nephrosky #criticalcare #medsky

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Sep 3

#ACIP is taking public comments..!

Get yours in TODAY!

#idsky #medsky

www.regulations.gov/docket/CDC-2...

@idvilchez.bsky.social @bradspellberg.bsky.social @wwrighid.bsky.social @paulsaxmd.bsky.social @astmh.bsky.social @alt-hhs.altgov.info @idsainfo.bsky.social @idstewardship.bsky.social

Regulations.gov

www.regulations.gov

James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Sep 3

I appreciate IV APAP, but unfortunately it also leads to mutations…
But yea, stuff WORKS for pain and fevers! “Surgeons only,” such BS

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 28

Couldn’t agree more!
Don’t know how I could tell people to sit at home febrile but unable to mitigate their fevers, etc.

James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 28

Love it
Real world application is..?

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 26

Is the new @natmicrobiol.nature.com study about Cipro and NSAIDs and APAP, is this practice changing for you?
Reply:
1 yes!
2 …ehhhhh…
3 need in vivo data
4 what study..?
#idsky #medsky

Joseph Marcus @josephmarcusid.medsky.social · Aug 26

Combining ibuprofen or acetaminophen with ciprofloxacin in vitro greatly increases mutagenesis for genes leading to cipro-resistance.

(Not the case for diclofenac, furosemide, metformin, atorvastatin, tramadol, temazepam, and pseudoephedrine)

#IDSky

www.nature.com/articles/s44...

The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli - npj Antimicrobials and Resistance

npj Antimicrobials and Resistance - The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli

www.nature.com

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 26

My thoughts exactly..!

I mean… fever control with pneumonia or UTI… how OFTEN are we giving NSAIDs and APAP..?!

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 22

Another plug for #wikiguidelines @bradspellberg.bsky.social
When guidelines don’t keep up with medicine

UNMC Infectious Diseases Division @unmc-id.bsky.social · Aug 22

UNMC ID faculty Dr. Jenn Davis and 🌟 resident Dr. Gigi Green joined up to publish an interesting case in @cidjournal.bsky.social as part of the Clinical Delimmas in ID series:

"A Blurry Line: Navigating Treatment Decisions When the Guidelines Don't Fit"

#IDSky

academic.oup.com/cid/advance-...

A Blurry Line: Navigating Treatment Decisions When the Guidelines Don’t Fit

A 45-year-old female was referred to the infectious diseases (ID) clinic for interpretation of discordant human immunodeficiency virus (HIV) test results.

academic.oup.com

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 18

Re: #PLSF
#medsky #idsky

www.instagram.com/p/DNeY_yKK0E...

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 12

@accpchest.bsky.social #idcrit

Cool. Can we skip fellowship now? Just apprentice as physicians? Why do ANY medical training AT ALL?!

What is this assault on physicians? Be willing to staff appropriately. Let an IM or FP or EM PHYSICIAN take a bronch course and cover the ICU before an NPP!!

James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

@idvilchez.bsky.social @bradspellberg.bsky.social @pulmcrit.bsky.social @mbrigmon.bsky.social @fungaldoc.bsky.social @boghuma.bsky.social @dralicehan.bsky.social @vipsmdmed.bsky.social @drtoddlee.bsky.social

#idsky #medsky #pulmsky #criticalcare #FOAMed #FOAMcc #FOAMid #FOAMim #melioidosis

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

Reviews on Melioidosis:
pubmed.ncbi.nlm.nih.gov/22057702/

pubmed.ncbi.nlm.nih.gov/31129946/

pubmed.ncbi.nlm.nih.gov/32161067/

9/x

Clinical features and epidemiology of melioidosis pneumonia: results from a 21-year study and review of the literature - PubMed

Melioidosis pneumonia is often a rapidly progressive illness with high mortality, particularly among those with multilobar disease. Risk factors have been identified, and early diagnosis and treatment...

pubmed.ncbi.nlm.nih.gov

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

US outbreak:

pubmed.ncbi.nlm.nih.gov/35235727/

8/x

Multistate Outbreak of Melioidosis Associated with Imported Aromatherapy Spray - PubMed

Melioidosis, caused by the bacterium <i>Burkholderia pseudomallei,</i> is an uncommon infection that is typically associated with exposure to soil and water in tropical and subtropical environments. I...

pubmed.ncbi.nlm.nih.gov

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

Plan to continue the Doxy for three months. Bactrim is generally more noted as primary with Doxy as alternative therapy for eradication, the taxes are much more benign, chronic drug than Bactrim.

7/x

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

Ceftazidime may work for uncomplicated pneumonia, would recommend Merrem plus Doxy if concern for shock with AMS to get better CNS penetration.

6/x

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

So from that standpoint, take it with a grain of salt. But I would be concerned if you start seeing a typical pneumonia that are not responding to our typical CAP/HAP coverage.

5/x

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

If so, throw on your BDLS hats and notify those responsible in your chain. I’d be most concerned, obviously for Texas at this moment. I am not and have never been, however, a disaster response physician, or Director.

4/x

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

I bring this up so that everyone has their radar up for typical pneumonia if they suddenly show up in a cluster.

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

Yes, #melioidosis can be used as a bioterrorism option. But as I mentioned in the text messages, there was one or a small number of cases from the Midwest (Ohio?) a few years back (2021?) linked to an essential oils product out of Walmart imported from Southeast Asia.

2/x

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James Wilson, DO, FACP, FAWM, CTropMed @jameswilsondo.bsky.social · Aug 9

Hello physician community. And especially our emergency, infectious diseases, pulmonary docs.

Had a friend reach out about a case in Texas of Melioidosis (Burkholderia pseudomallei) in a patient without a travel history.

#idcrit #idsky #Pulmsky #EMsky #emcrit #pulmcrit #bioterrorism

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