Em testes pré-clínicos conduzidos na USP de São Carlos, compostos denominados batzelladinas foram eficazes até contra cepas de <i>Plasmodium</i> resistentes aos antimaláricos convencionais

Entrevista com professor titular do Departamento de Bioquímica do Instituto de Química da USP João Carlos Setubal .

Características de memória imune social foram observadas por pesquisadores da Unesp e colaboradores em colônias de formigas-cortadeiras expostas a quatro diferentes fungos patogênicos

Ending clinical trials with no warning can put patients at risk.

Entrevista com a bióloga molecular Mayana Zatz, coordenadora do Centro de Pesquisas sobre o Genoma Humano e Células-Tronco (CEGH-CEL) e com a biomédica Helena Nader, presidente da Academia Brasileira ...

The burden of proof is on us, as researchers, to explain why what we do is valuable to society.

The U.S. life science research mission is critical not only to human health and understanding the natural world but also to agriculture and food production, technological innovations, socioeconomic pr...

Phagocytosed bacteria can serve as an alternative nutrient source for macrophages, influencing their metabolic and immune responses through the recycling of microbial components, with the process regu...

Disruption of mucin-domain glycoprotein expression and function in the endothelial glycocalyx are associated with ageing and Alzheimer’s disease, leading to dysregulated blood–brain barrier function.

Background Less than 0.5% of people living with HIV-1 are elite controllers (ECs)—individuals who maintain undetectable plasma viremia without antiretroviral therapy, despite having replication-compet...

Qual seria o lugar com maior probabilidade de haver microrganismos especializados em quebrar a parede celular da cana-de-açúcar, descontruir a celulose, um carboidrato longo que dá rigidez às plantas ...

There are many large language models to choose from; some excel at coding, whereas others are better for synthesizing information.

EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

Tu Youyou is a Chinese pharmaceutical chemist whose unique training in the classification of medical plants and their active ingredients resulted...

YouTube video by Agência FAPESP

Jogadoras de Rugby Sevens participaram de estudo da USP sobre atividade cerebral após períodos prolongados de estresse e repetidos impactos na cabeça​

Divangahi and colleagues report that β-glucan pretreatment before influenza A virus challenge can increase survival by inducing long-term reprogramming of neutrophils, promoting disease tolerance irre...

Malaria predisposes to concomitant bacteremia, resulting in increased mortality risk. Previous studies indicated that malaria causes structural changes in the intestine, induces tolerogenic immune responses, inhibits neutrophil recruitment, suppresses innate synthesis of IFN-γ, dysregulates mast cells (MCs) and basophils, and induces Th2-type immune responses. These can reduce parasite control while increasing enteropathogenic dissemination. Moreover, there is growing evidence that Th2 immunity, while protecting the host from overwhelming inflammation, may also contribute to increased parasite transmission. This review explores the roles of the regulatory immune response in bacterial coinfections and parasite transmission in malaria.

As duas principais formas de demência – a doença de Alzheimer e a demência vascular – não atingem brancos e negros no Brasil de maneira uniforme. Em ambos os grupos, o Alzheimer é a enfermidade que co...