Marc Lensink
@marclensink.bsky.social
CNRS scientist computational molecular biology. Mostly talking about life, travel, science and board games, unless it's something else.
Pinned
Marc Lensink
@marclensink.bsky.social
· Nov 17
Lots of influx & new followers, so time for a short introduction. I put molecules together and make them wiggle, although I would like them not to. #structuralbiology #bioinformatics #capri #proteininteraction #evolution. May also post about my travels, board games, and various other topics.
Visiting Utrecht University
November 23, 2025 at 11:22 PM
Visiting Utrecht University
Reposted by Marc Lensink
It’s widely known (and, I think, pretty uncontroversial) that learning requires effort — specifically, if you don’t have to work at getting the knowledge, it won’t stick.
Even if an LLM could be trusted to give you correct information 100% of the time, it would be an inferior method of learning it.
Even if an LLM could be trusted to give you correct information 100% of the time, it would be an inferior method of learning it.
Relying on ChatGPT to teach you about a topic leaves you with shallower knowledge than Googling and reading about it, according to new research that compared what more than 10,000 people knew after using one method or the other.
Shared by @gizmodo.com: buff.ly/yAAHtHq
Shared by @gizmodo.com: buff.ly/yAAHtHq
November 21, 2025 at 12:49 PM
It’s widely known (and, I think, pretty uncontroversial) that learning requires effort — specifically, if you don’t have to work at getting the knowledge, it won’t stick.
Even if an LLM could be trusted to give you correct information 100% of the time, it would be an inferior method of learning it.
Even if an LLM could be trusted to give you correct information 100% of the time, it would be an inferior method of learning it.
Reposted by Marc Lensink
Unsurprisingly, Grok is a piece of crap designed to glorify Musk and his neo-Nazi ideology.
The most worrying thing is that tens of thousands of people use this crap every day to get information.
The most worrying thing is that tens of thousands of people use this crap every day to get information.
November 20, 2025 at 3:25 PM
Unsurprisingly, Grok is a piece of crap designed to glorify Musk and his neo-Nazi ideology.
The most worrying thing is that tens of thousands of people use this crap every day to get information.
The most worrying thing is that tens of thousands of people use this crap every day to get information.
Reposted by Marc Lensink
Did you know you can find over 1 million preprints on Europe PMC?
With a single search, you can explore preprints from 34 servers, including #PsyArXiv, alongside peer reviewed journal articles.
One platform making over 47 million research outputs searchable in one place!
#Preprints #OpenScience
With a single search, you can explore preprints from 34 servers, including #PsyArXiv, alongside peer reviewed journal articles.
One platform making over 47 million research outputs searchable in one place!
#Preprints #OpenScience
When you share a preprint on #PsyArXiv, it becomes discoverable through
Google Scholar,
@europepmc.org
OpenAlex
@dimensions.ai
OSF Preprints
@crossref.bsky.social Metadata Search
@orcid.org
and more!
blog.psyarxiv.com/2025/11/10/d... by Andrea Schuler
#AcademicSky #OpenScience
@improvingpsych.org
Google Scholar,
@europepmc.org
OpenAlex
@dimensions.ai
OSF Preprints
@crossref.bsky.social Metadata Search
@orcid.org
and more!
blog.psyarxiv.com/2025/11/10/d... by Andrea Schuler
#AcademicSky #OpenScience
@improvingpsych.org
Discovering research from PsyArXiv – PsyArXiv Blog
When you share a preprint in PsyArXiv it becomes available for a worldwide audience to read, share, and cite. Readers may access your work via its DOI, by searching the PsyArXiv site, or by discoverin...
blog.psyarxiv.com
November 20, 2025 at 3:01 PM
Did you know you can find over 1 million preprints on Europe PMC?
With a single search, you can explore preprints from 34 servers, including #PsyArXiv, alongside peer reviewed journal articles.
One platform making over 47 million research outputs searchable in one place!
#Preprints #OpenScience
With a single search, you can explore preprints from 34 servers, including #PsyArXiv, alongside peer reviewed journal articles.
One platform making over 47 million research outputs searchable in one place!
#Preprints #OpenScience
Reposted by Marc Lensink
Helpful reminder that both Kyiv and its European partners can safely ignore Trump's pushes for a bad peace deal.
Keep in mind that since this year, it is us Europeans who pay for all the aid to Ukraine. Nothing comes from the U.S since Trump became president. We even pay for the American weapons bought for Ukraine.
November 20, 2025 at 11:33 AM
Helpful reminder that both Kyiv and its European partners can safely ignore Trump's pushes for a bad peace deal.
Reposted by Marc Lensink
We are thrilled to now be on BlueSky!
We prioritize studies addressing critical health challenges—from major diseases to health equity—that bridge scientific rigor with real-world impact, connecting researchers, clinicians, and policymakers to advance global health 🧬🧪
#OpenScience #MedSky
We prioritize studies addressing critical health challenges—from major diseases to health equity—that bridge scientific rigor with real-world impact, connecting researchers, clinicians, and policymakers to advance global health 🧬🧪
#OpenScience #MedSky
November 20, 2025 at 2:31 PM
We are thrilled to now be on BlueSky!
We prioritize studies addressing critical health challenges—from major diseases to health equity—that bridge scientific rigor with real-world impact, connecting researchers, clinicians, and policymakers to advance global health 🧬🧪
#OpenScience #MedSky
We prioritize studies addressing critical health challenges—from major diseases to health equity—that bridge scientific rigor with real-world impact, connecting researchers, clinicians, and policymakers to advance global health 🧬🧪
#OpenScience #MedSky
Reposted by Marc Lensink
Check the list of confirmed speakers for the MDDB Conference and apply to be part of this excellent lineup ➡️ mddbr.eu/conference/
Present your work, connect with leading experts from the community, and be part of the discussions shaping the future of MD research!
#MDDB #FAIRdata
Present your work, connect with leading experts from the community, and be part of the discussions shaping the future of MD research!
#MDDB #FAIRdata
November 20, 2025 at 10:43 AM
Check the list of confirmed speakers for the MDDB Conference and apply to be part of this excellent lineup ➡️ mddbr.eu/conference/
Present your work, connect with leading experts from the community, and be part of the discussions shaping the future of MD research!
#MDDB #FAIRdata
Present your work, connect with leading experts from the community, and be part of the discussions shaping the future of MD research!
#MDDB #FAIRdata
Reposted by Marc Lensink
Dang, hard disagree. The best papers to write and read are works of art, not merely a list of data and statements.
Don’t let LLMs take this away too, for gods sake.
Don’t let LLMs take this away too, for gods sake.
I honestly think we would all be a lot more productive if papers were bullet points with plots.
November 14, 2025 at 10:22 PM
Dang, hard disagree. The best papers to write and read are works of art, not merely a list of data and statements.
Don’t let LLMs take this away too, for gods sake.
Don’t let LLMs take this away too, for gods sake.
Reposted by Marc Lensink
Open AI loses copyright case in Germany.
Judge Elke Schwager summarized the case saying that if you want to build something and need components, "then you purchase them and do not use the property of others."
Judge Elke Schwager summarized the case saying that if you want to build something and need components, "then you purchase them and do not use the property of others."
Blow for OpenAI in Germany as court rules song lyrics used illegally
A German court ruled on Tuesday that OpenAI violated copyright on nine popular songs in a lawsuit that marked another attempt to prevent the free use of artists' content online. The Munich Regional Co...
www.yahoo.com
November 14, 2025 at 2:49 PM
Open AI loses copyright case in Germany.
Judge Elke Schwager summarized the case saying that if you want to build something and need components, "then you purchase them and do not use the property of others."
Judge Elke Schwager summarized the case saying that if you want to build something and need components, "then you purchase them and do not use the property of others."
Reposted by Marc Lensink
Donetsk Oblast.
The military arrived to get people out, but there was no one left, only ruins.
russia exiles people from their homes, by destroying entire cities.
Let’s not let them:
u24.gov.ua/nafo-dark-ni...
The military arrived to get people out, but there was no one left, only ruins.
russia exiles people from their homes, by destroying entire cities.
Let’s not let them:
u24.gov.ua/nafo-dark-ni...
November 8, 2025 at 7:55 PM
Donetsk Oblast.
The military arrived to get people out, but there was no one left, only ruins.
russia exiles people from their homes, by destroying entire cities.
Let’s not let them:
u24.gov.ua/nafo-dark-ni...
The military arrived to get people out, but there was no one left, only ruins.
russia exiles people from their homes, by destroying entire cities.
Let’s not let them:
u24.gov.ua/nafo-dark-ni...
Reposted by Marc Lensink
Mariupol, Bakhmut, Vovchansk, Toretsk, Chasiv Yar, Vuhledar, Velyka Novosilka, Avdiivka, Pokrovsk, Kupyansk, Myrnohrad - and many, many more. City after city, annihilated by Russia. #Ukraine
This is what Myrnohrad looks like now.
As of January 1, 2022, Myrnohrad had a population of over 47 thousand people. Today, the Russians have destroyed this town.
As of January 1, 2022, Myrnohrad had a population of over 47 thousand people. Today, the Russians have destroyed this town.
November 8, 2025 at 6:47 PM
Mariupol, Bakhmut, Vovchansk, Toretsk, Chasiv Yar, Vuhledar, Velyka Novosilka, Avdiivka, Pokrovsk, Kupyansk, Myrnohrad - and many, many more. City after city, annihilated by Russia. #Ukraine
Reposted by Marc Lensink
Vandaag pas geleerd: voor 3 euro koop je in een Belgische kaartautomaat voor een maand Rail+ en je reist per direct met 40% korting in daluren of voor 24 euro voor een heel jaar dalkorting met de trein in België. Praktisch
November 8, 2025 at 9:14 AM
Vandaag pas geleerd: voor 3 euro koop je in een Belgische kaartautomaat voor een maand Rail+ en je reist per direct met 40% korting in daluren of voor 24 euro voor een heel jaar dalkorting met de trein in België. Praktisch
Reposted by Marc Lensink
Some still praise James Watson despite his racism. Same with colleagues who won’t condemn Elon Musk’s politics, hiding behind “scientists shouldn’t mix science and politics.”
November 8, 2025 at 12:36 PM
Some still praise James Watson despite his racism. Same with colleagues who won’t condemn Elon Musk’s politics, hiding behind “scientists shouldn’t mix science and politics.”
Reposted by Marc Lensink
Reposted by Marc Lensink
6. The integrity measures used to contain systematic scientific fraud are dwarfed in scale by the problem itself.
August 4, 2025 at 8:47 PM
6. The integrity measures used to contain systematic scientific fraud are dwarfed in scale by the problem itself.
Reposted by Marc Lensink
This is what a New Era looks like.
November 5, 2025 at 11:57 PM
This is what a New Era looks like.
Pour ceux qui s'intéresseraient au paysage politique néerlandais fragmenté
Les chrétiens démocrates semblent ressusciter leur électorat classique. Ils récupèrent ainsi bon nombre du NSC. On voit aussi des voix du VVD, probablement leur aile modérée (mais pas urbaine) qui a peu apprécié le chaos gouvernemental."
CDA anti-chaos partij. open.substack.com/pub/voltphre...
CDA anti-chaos partij. open.substack.com/pub/voltphre...
Petit détour aux Pays Bas
Et son paysage partisan si particulier
open.substack.com
November 3, 2025 at 7:27 PM
Pour ceux qui s'intéresseraient au paysage politique néerlandais fragmenté
Reposted by Marc Lensink
Bonjour! Masters students in France 🇫🇷, we’ve got an internship for you, in collaboration with the French Embassy in London.
Aimed at students of computer science, statistics or bioinformatics.
Deadline: 7 December 2025
Find out more and apply:
www.ebi.ac.uk/about/jobs/i...
Aimed at students of computer science, statistics or bioinformatics.
Deadline: 7 December 2025
Find out more and apply:
www.ebi.ac.uk/about/jobs/i...
November 3, 2025 at 11:00 AM
Bonjour! Masters students in France 🇫🇷, we’ve got an internship for you, in collaboration with the French Embassy in London.
Aimed at students of computer science, statistics or bioinformatics.
Deadline: 7 December 2025
Find out more and apply:
www.ebi.ac.uk/about/jobs/i...
Aimed at students of computer science, statistics or bioinformatics.
Deadline: 7 December 2025
Find out more and apply:
www.ebi.ac.uk/about/jobs/i...
Reposted by Marc Lensink
This is quite a story: the US employed every strongarm tactic available, including personal threats against delegates and their families, to derail an agreement on reducing shipping emissions that was almost finalized. on.ft.com/47lq3dZ
November 3, 2025 at 2:11 PM
This is quite a story: the US employed every strongarm tactic available, including personal threats against delegates and their families, to derail an agreement on reducing shipping emissions that was almost finalized. on.ft.com/47lq3dZ
Reposted by Marc Lensink
Nighttime walks in the rain. Brussels. October 2025.
October 31, 2025 at 11:56 PM
Nighttime walks in the rain. Brussels. October 2025.
Reposted by Marc Lensink
Can't overstate how fucked up it is that unraveling what is arguably the greatest achievement in the history of humanity is now a motivating issue of one of the two dominant parties in the U.S.
FL is moving forward w/ plan to end all childhood vaccine mandates. Starting with hepatitis B, chickenpox, and the bacteria causing meningitis and pneumonia. Then next year GOP FL legislature is expected to revisit 1977 law re: whooping cough, measles, polio, rubella, mumps, diphtheria, and tetanus.
October 31, 2025 at 4:13 AM
Can't overstate how fucked up it is that unraveling what is arguably the greatest achievement in the history of humanity is now a motivating issue of one of the two dominant parties in the U.S.
Reposted by Marc Lensink
ladies and gentlemen...we got him
October 30, 2025 at 7:10 PM
ladies and gentlemen...we got him
Saw him talk once pre-Nobel. You don't want to miss this
Join us for an extraordinary evening with Nobel Laureate Svante Pääbo!
Prof Pääbo will present a FREE public talk titled “Of Neanderthals and Denisovans, and how they live on in many of us” at the @crick.ac.uk.
Register here: genetics.org.uk/events/of-ne...
Prof Pääbo will present a FREE public talk titled “Of Neanderthals and Denisovans, and how they live on in many of us” at the @crick.ac.uk.
Register here: genetics.org.uk/events/of-ne...
October 29, 2025 at 12:02 AM
Saw him talk once pre-Nobel. You don't want to miss this
Reposted by Marc Lensink
Just because this came up a few times recently
If you need to compare two or more ensembles (like RMSD for structures) we developed algorithms and code (ENCORE) to do just that
Similarity Measures for Protein Ensembles
journals.plos.org/plosone/arti...
ENCORE
journals.plos.org/ploscompbiol...
If you need to compare two or more ensembles (like RMSD for structures) we developed algorithms and code (ENCORE) to do just that
Similarity Measures for Protein Ensembles
journals.plos.org/plosone/arti...
ENCORE
journals.plos.org/ploscompbiol...
October 27, 2025 at 8:00 AM
Just because this came up a few times recently
If you need to compare two or more ensembles (like RMSD for structures) we developed algorithms and code (ENCORE) to do just that
Similarity Measures for Protein Ensembles
journals.plos.org/plosone/arti...
ENCORE
journals.plos.org/ploscompbiol...
If you need to compare two or more ensembles (like RMSD for structures) we developed algorithms and code (ENCORE) to do just that
Similarity Measures for Protein Ensembles
journals.plos.org/plosone/arti...
ENCORE
journals.plos.org/ploscompbiol...
Reposted by Marc Lensink
After two chaotic years, this Dutch anti-populist's message of decency, stability and trust is suddenly resonating with voters.
Make boring great again: Dutch anti-populist’s plan to beat Wilders
‘I’m not ordered to be the funniest or to make the craziest remarks,’ said Christian Democrat Henri Bontenbal.
www.politico.eu
October 27, 2025 at 12:16 PM
After two chaotic years, this Dutch anti-populist's message of decency, stability and trust is suddenly resonating with voters.