Matthew Baggott
@mattbagg.bsky.social
Scientist, CEO @ Tactogen
Reposted by Matthew Baggott
This Thursday at noon. Join us (over Zoom) for the MIT Consciousness Club.
George Mashour (University of Michigan Medical School) - "Consciousness and the Dying Brain"
sites.google.com/view/mit-con...
#neuroscience
George Mashour (University of Michigan Medical School) - "Consciousness and the Dying Brain"
sites.google.com/view/mit-con...
#neuroscience
January 20, 2026 at 1:50 PM
This Thursday at noon. Join us (over Zoom) for the MIT Consciousness Club.
George Mashour (University of Michigan Medical School) - "Consciousness and the Dying Brain"
sites.google.com/view/mit-con...
#neuroscience
George Mashour (University of Michigan Medical School) - "Consciousness and the Dying Brain"
sites.google.com/view/mit-con...
#neuroscience
Reposted by Matthew Baggott
An interview by Nick Dirks from New York Academy of Science about medical anthropology and psychedelics. www.nyas.org/ideas-insigh...
Neuropsychedelia and the Decade of the Brain
Nicolas Langlitz, discusses medical anthropology, the anti-psychiatric movement, and the potential of LSD.
www.nyas.org
January 13, 2026 at 1:48 PM
An interview by Nick Dirks from New York Academy of Science about medical anthropology and psychedelics. www.nyas.org/ideas-insigh...
Reposted by Matthew Baggott
I keep repeating it because its insane to me but the idea of invading or acquiring Greenland for missile defense is insane because we already have access to it for our missile defense
January 11, 2026 at 3:47 AM
I keep repeating it because its insane to me but the idea of invading or acquiring Greenland for missile defense is insane because we already have access to it for our missile defense
Here, again, is a feed of all the Democratic members of Congress. bsky.app/profile/did:...
January 3, 2026 at 3:26 PM
Here, again, is a feed of all the Democratic members of Congress. bsky.app/profile/did:...
Reposted by Matthew Baggott
I’m facilitating the rehoming of two sweet cats who belonged to a friend who recently passed unexpectedly. They deserve a stable place to land. 2-3 year old bonded pair, one male one female. Please send me a DM if you have the interest and ability to care for these sweet voids. Located in Oakland.
December 30, 2025 at 4:12 AM
I’m facilitating the rehoming of two sweet cats who belonged to a friend who recently passed unexpectedly. They deserve a stable place to land. 2-3 year old bonded pair, one male one female. Please send me a DM if you have the interest and ability to care for these sweet voids. Located in Oakland.
Reposted by Matthew Baggott
IT FINALLY HAPPENED I AM ON A PLANE WITH A BABY WHO SAYS “HI” TO EVERYONE AS HE GOES DOWN THE AISLE
December 24, 2025 at 8:31 PM
IT FINALLY HAPPENED I AM ON A PLANE WITH A BABY WHO SAYS “HI” TO EVERYONE AS HE GOES DOWN THE AISLE
One third of SF without power rn pgealerts.alerts.pge.com/outage-tools...
December 21, 2025 at 2:01 AM
One third of SF without power rn pgealerts.alerts.pge.com/outage-tools...
Trump just officially signed off on moving cannabis to Schedule III
December 18, 2025 at 8:02 PM
Trump just officially signed off on moving cannabis to Schedule III
Reposted by Matthew Baggott
For those looking for a new browser, I'm happy with Vivaldi. vivaldi.com/for-a-better...
December 17, 2025 at 1:42 AM
For those looking for a new browser, I'm happy with Vivaldi. vivaldi.com/for-a-better...
For those looking for a new browser, I'm happy with Vivaldi. vivaldi.com/for-a-better...
December 17, 2025 at 1:42 AM
For those looking for a new browser, I'm happy with Vivaldi. vivaldi.com/for-a-better...
Reposted by Matthew Baggott
I'm not sure if people realize the murder strikes are taking place across a large region. It's quite staggering.
www.newsweek.com/map-us-strik...
www.newsweek.com/map-us-strik...
December 16, 2025 at 4:00 PM
I'm not sure if people realize the murder strikes are taking place across a large region. It's quite staggering.
www.newsweek.com/map-us-strik...
www.newsweek.com/map-us-strik...
Reposted by Matthew Baggott
Have any of my academic friends applied for the ARPA-H EVIDENT program?
If so, I’d love to chat with you for a story I’m working on about how it could impact the industry.
Feel free to DM or reply to this post!
If so, I’d love to chat with you for a story I’m working on about how it could impact the industry.
Feel free to DM or reply to this post!
December 16, 2025 at 3:51 AM
Have any of my academic friends applied for the ARPA-H EVIDENT program?
If so, I’d love to chat with you for a story I’m working on about how it could impact the industry.
Feel free to DM or reply to this post!
If so, I’d love to chat with you for a story I’m working on about how it could impact the industry.
Feel free to DM or reply to this post!
Reposted by Matthew Baggott
🐁 Very concerning finding: Psilocybin promotes brain tumour growth
Authors caution against use of 5-HT2A agonists like psilocybin in patients with glioma, "given the profound and sustained tumor growth-promoting effects observed."
Extends to other serotonergic drugs like LSD.
Authors caution against use of 5-HT2A agonists like psilocybin in patients with glioma, "given the profound and sustained tumor growth-promoting effects observed."
Extends to other serotonergic drugs like LSD.
December 15, 2025 at 3:47 PM
🐁 Very concerning finding: Psilocybin promotes brain tumour growth
Authors caution against use of 5-HT2A agonists like psilocybin in patients with glioma, "given the profound and sustained tumor growth-promoting effects observed."
Extends to other serotonergic drugs like LSD.
Authors caution against use of 5-HT2A agonists like psilocybin in patients with glioma, "given the profound and sustained tumor growth-promoting effects observed."
Extends to other serotonergic drugs like LSD.
Reposted by Matthew Baggott
Bluntly, Section 230 is almost literally the law that the entire internet rests upon, it makes it possible for user generated content to exist on the internet, it’s incredibly important, and genuinely we must defend it at all costs. This place literally would not exist without it.
December 14, 2025 at 6:05 AM
Bluntly, Section 230 is almost literally the law that the entire internet rests upon, it makes it possible for user generated content to exist on the internet, it’s incredibly important, and genuinely we must defend it at all costs. This place literally would not exist without it.
Reposted by Matthew Baggott
New study challenges the idea of a unified decision network: Neuropixel recordings in primate OFC showed robust encoding during value-based choices but near-silence during perceptual decisions, even when rewards are at stake. #RewardSignals #neuroskyence www.biorxiv.org/content/10.1...
Selective engagement of the primate orbitofrontal cortex during value-based but not perceptual decisions
A fundamental question in neuroscience is whether the brain uses specialized sub-systems for different types of decisions or relies on a unified decision-making network. The orbitofrontal cortex (OFC)...
www.biorxiv.org
December 12, 2025 at 9:12 PM
New study challenges the idea of a unified decision network: Neuropixel recordings in primate OFC showed robust encoding during value-based choices but near-silence during perceptual decisions, even when rewards are at stake. #RewardSignals #neuroskyence www.biorxiv.org/content/10.1...
Reposted by Matthew Baggott
Asking for some help.
I'm working with someone who is designing a pilot to study the uptake of PFAS chemicals by mushrooms for purposes of remediation.
Does ANYONE have a contact for a mycologist or someone who knows about mushrooms? If so, can you point them my way? Many thanks.
I'm working with someone who is designing a pilot to study the uptake of PFAS chemicals by mushrooms for purposes of remediation.
Does ANYONE have a contact for a mycologist or someone who knows about mushrooms? If so, can you point them my way? Many thanks.
December 11, 2025 at 9:08 PM
Asking for some help.
I'm working with someone who is designing a pilot to study the uptake of PFAS chemicals by mushrooms for purposes of remediation.
Does ANYONE have a contact for a mycologist or someone who knows about mushrooms? If so, can you point them my way? Many thanks.
I'm working with someone who is designing a pilot to study the uptake of PFAS chemicals by mushrooms for purposes of remediation.
Does ANYONE have a contact for a mycologist or someone who knows about mushrooms? If so, can you point them my way? Many thanks.
Reposted by Matthew Baggott
The Psychedelic Practitioner Issue 2: Preparation
We explore the science and practice of psychedelic preparation through interviews, research reviews, and practitioner insights.
Read now: psychedelicalpha.com/news/the-psy...
We explore the science and practice of psychedelic preparation through interviews, research reviews, and practitioner insights.
Read now: psychedelicalpha.com/news/the-psy...
December 11, 2025 at 4:40 PM
The Psychedelic Practitioner Issue 2: Preparation
We explore the science and practice of psychedelic preparation through interviews, research reviews, and practitioner insights.
Read now: psychedelicalpha.com/news/the-psy...
We explore the science and practice of psychedelic preparation through interviews, research reviews, and practitioner insights.
Read now: psychedelicalpha.com/news/the-psy...
Reposted by Matthew Baggott
Check out this awesome new preprint which assessed mental health outcomes over four years (!) in groups of adult and adolescent cannabis users (and non-using controls):
osf.io/preprints/ps...
osf.io/preprints/ps...
OSF
osf.io
December 11, 2025 at 12:50 PM
Check out this awesome new preprint which assessed mental health outcomes over four years (!) in groups of adult and adolescent cannabis users (and non-using controls):
osf.io/preprints/ps...
osf.io/preprints/ps...
Reposted by Matthew Baggott
A lot of interest in PET imaging of synaptic markers in humans after psychedelics.
This preprint from Knudsen lab may be the first. People treated in therapeutic-like setting had more intense experiences and greater increases in synaptic density than those dosed in MRI scanner. tinyurl.com/36vv6a9v
This preprint from Knudsen lab may be the first. People treated in therapeutic-like setting had more intense experiences and greater increases in synaptic density than those dosed in MRI scanner. tinyurl.com/36vv6a9v
December 9, 2025 at 7:17 PM
A lot of interest in PET imaging of synaptic markers in humans after psychedelics.
This preprint from Knudsen lab may be the first. People treated in therapeutic-like setting had more intense experiences and greater increases in synaptic density than those dosed in MRI scanner. tinyurl.com/36vv6a9v
This preprint from Knudsen lab may be the first. People treated in therapeutic-like setting had more intense experiences and greater increases in synaptic density than those dosed in MRI scanner. tinyurl.com/36vv6a9v
(all of us)
he’s only mad because he doesn’t know he has perfect little snowflakes on his sweet little head
December 5, 2025 at 4:12 PM
(all of us)
Reposted by Matthew Baggott
New on the Archive:
Simons, Massimiliano (2026) What is the history of philosophy of experimentation a history of? The cases of Hugo Dingler and Gaston Bachelard. HOPOS: The Journal of the International Society for the History of Philosophy of Science.
https://philsci-archive.pitt.edu/27380/
Simons, Massimiliano (2026) What is the history of philosophy of experimentation a history of? The cases of Hugo Dingler and Gaston Bachelard. HOPOS: The Journal of the International Society for the History of Philosophy of Science.
https://philsci-archive.pitt.edu/27380/
December 5, 2025 at 2:16 PM
New on the Archive:
Simons, Massimiliano (2026) What is the history of philosophy of experimentation a history of? The cases of Hugo Dingler and Gaston Bachelard. HOPOS: The Journal of the International Society for the History of Philosophy of Science.
https://philsci-archive.pitt.edu/27380/
Simons, Massimiliano (2026) What is the history of philosophy of experimentation a history of? The cases of Hugo Dingler and Gaston Bachelard. HOPOS: The Journal of the International Society for the History of Philosophy of Science.
https://philsci-archive.pitt.edu/27380/
Reposted by Matthew Baggott
Check out a new article out now from DDRU Director, M. Baumann & colleagues regarding transporter activities of prolintanes.
"Prolintane analogs as hybrid monoamine transporter ligands: Structural determinants and species differences"
www.sciencedirect.com/science/arti...
"Prolintane analogs as hybrid monoamine transporter ligands: Structural determinants and species differences"
www.sciencedirect.com/science/arti...
December 4, 2025 at 4:25 PM
Check out a new article out now from DDRU Director, M. Baumann & colleagues regarding transporter activities of prolintanes.
"Prolintane analogs as hybrid monoamine transporter ligands: Structural determinants and species differences"
www.sciencedirect.com/science/arti...
"Prolintane analogs as hybrid monoamine transporter ligands: Structural determinants and species differences"
www.sciencedirect.com/science/arti...
The great Erik Davis on the War on Empathy
substack.com/app-link/pos...
substack.com/app-link/pos...
December 3, 2025 at 4:27 PM
The great Erik Davis on the War on Empathy
substack.com/app-link/pos...
substack.com/app-link/pos...