Melania D'Angiolo
@melaniadangiolo.bsky.social
Postdoc in Jurg Bahler's lab at UCL. Former PhD student in Gianni Liti's lab. Interested in genomics, evolution, systems biology and telomeres. Fission and budding yeasts enthusiast.
Communications & Engagement manager for @yeast-journal.bsky.social
Communications & Engagement manager for @yeast-journal.bsky.social
Pinned
The adaptive molecular landscape of reprogrammed telomeric sequences
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...
www.biorxiv.org
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Melania D'Angiolo
🚨 PhD opportunity in Strasbourg! 🚨
We’re looking for a motivated PhD student to join the @haploteam within the IMCBio program (PhD-2026-17).
🔗 imcbio-phdprogram.unistra.fr
Please spread the word or contact me if you’re interested!
We’re looking for a motivated PhD student to join the @haploteam within the IMCBio program (PhD-2026-17).
🔗 imcbio-phdprogram.unistra.fr
Please spread the word or contact me if you’re interested!
IMCBio International PhD Program
IMCBio International PhD Program - Application form
imcbio-phdprogram.unistra.fr
November 27, 2025 at 6:17 AM
🚨 PhD opportunity in Strasbourg! 🚨
We’re looking for a motivated PhD student to join the @haploteam within the IMCBio program (PhD-2026-17).
🔗 imcbio-phdprogram.unistra.fr
Please spread the word or contact me if you’re interested!
We’re looking for a motivated PhD student to join the @haploteam within the IMCBio program (PhD-2026-17).
🔗 imcbio-phdprogram.unistra.fr
Please spread the word or contact me if you’re interested!
Reposted by Melania D'Angiolo
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
November 24, 2025 at 4:57 PM
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
Reposted by Melania D'Angiolo
We are looking for PhD applicants! ‼️Interested in genomics, ecophysiology and adaptation? Look at our TREES DLA project:
www.trees-dla.ac.uk/projects/und...
We also offer more projects via ROUTE2. Get in touch and let’s have a chat 💬
www.trees-dla.ac.uk/projects/und...
We also offer more projects via ROUTE2. Get in touch and let’s have a chat 💬
Understanding the role of metabolism in adaptation & evolution | TREES DLA
In an era of rapid environmental change, understanding how species adapt to shifting conditions is critical for conservation biology. At the heart of adaptation lies metabolism, the process that fuels...
www.trees-dla.ac.uk
November 25, 2025 at 9:21 AM
We are looking for PhD applicants! ‼️Interested in genomics, ecophysiology and adaptation? Look at our TREES DLA project:
www.trees-dla.ac.uk/projects/und...
We also offer more projects via ROUTE2. Get in touch and let’s have a chat 💬
www.trees-dla.ac.uk/projects/und...
We also offer more projects via ROUTE2. Get in touch and let’s have a chat 💬
Reposted by Melania D'Angiolo
In this #Yeast review article, Jose Ribamar Ferreira-Junior, Vittoria de Lima Camandona & Mario H. Barros show how Saccharomyces cerevisiae can be used as a model to study the cellular processes underlying #neurodegenerative disorders and to test new drugs 💊
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
From Yeast to Therapeutics: Modeling Neurodegenerative Diseases in Saccharomyces cerevisiae
Yeast plasmids expressing human Aβ-42, α-syn, htt, and TDP-43. Their fate includes an equilibrium between the endocytic pathway and aggregates that potentially disrupt endocytosis, vesicular transpor...
onlinelibrary.wiley.com
November 25, 2025 at 10:49 AM
In this #Yeast review article, Jose Ribamar Ferreira-Junior, Vittoria de Lima Camandona & Mario H. Barros show how Saccharomyces cerevisiae can be used as a model to study the cellular processes underlying #neurodegenerative disorders and to test new drugs 💊
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Melania D'Angiolo
Our annual PhD call is closing at the end of this week on 30 November. If you're interested in carrying out world-class scientific research in Barcelona, you still have a few days left to submit your application! www.crg.eu/en/content/t...
November 25, 2025 at 7:43 AM
Our annual PhD call is closing at the end of this week on 30 November. If you're interested in carrying out world-class scientific research in Barcelona, you still have a few days left to submit your application! www.crg.eu/en/content/t...
Reposted by Melania D'Angiolo
My lab is recruiting a post-doc ! please share ! emploi.cnrs.fr/Offres/CDD/U...
November 14, 2025 at 2:27 PM
My lab is recruiting a post-doc ! please share ! emploi.cnrs.fr/Offres/CDD/U...
Reposted by Melania D'Angiolo
🧬 PomBase needs you! 🧬
If you PomBase on a regular basis, now it’s the time to show your support to the team behind this incredibly useful resource (and help them secure funding to keep up the amazing work). Fill out their short user survey, which they will use to support their grant application.
If you PomBase on a regular basis, now it’s the time to show your support to the team behind this incredibly useful resource (and help them secure funding to keep up the amazing work). Fill out their short user survey, which they will use to support their grant application.
If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey www.surveymonkey.com/r/7GXJL6X
November 12, 2025 at 8:55 PM
🧬 PomBase needs you! 🧬
If you PomBase on a regular basis, now it’s the time to show your support to the team behind this incredibly useful resource (and help them secure funding to keep up the amazing work). Fill out their short user survey, which they will use to support their grant application.
If you PomBase on a regular basis, now it’s the time to show your support to the team behind this incredibly useful resource (and help them secure funding to keep up the amazing work). Fill out their short user survey, which they will use to support their grant application.
Reposted by Melania D'Angiolo
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Reposted by Melania D'Angiolo
In the latest #Yeast research article, Miguel A. Rocha, Gowda Bhavani and Jacob Fleischmann investigate the role of exonuclease-resistant ribosomal RNAs in Saccharomyces cerevisiae, their relationship with nutritional status and the TOR signalling pathway.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
18S and 25S Exonuclease Resistant Ribosomal RNA Molecules Are Produced by 5′‐End Modification During TOR Inhibition.
Saccharomyces cerevisiae produces exonuclease-resistant rRNA molecules upon TOR inhibition. This phenomenon occurs when cells enter the diauxic phase, upon addition of rapamycin to the culture, or wh...
onlinelibrary.wiley.com
November 10, 2025 at 2:10 PM
In the latest #Yeast research article, Miguel A. Rocha, Gowda Bhavani and Jacob Fleischmann investigate the role of exonuclease-resistant ribosomal RNAs in Saccharomyces cerevisiae, their relationship with nutritional status and the TOR signalling pathway.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Melania D'Angiolo
If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey www.surveymonkey.com/r/7GXJL6X
October 30, 2025 at 11:44 AM
If you use PomBase, please help us to demonstrate our value, and make improvements by completing our user survey www.surveymonkey.com/r/7GXJL6X
Reposted by Melania D'Angiolo
🆕 Vacancy! We're looking for a Research Scientist to work on novel platforms for sustainable myco-food production and precision fermentation.
💷 £37,500 to £40,240
🗓️ Apply by 30 November 2025
➡️ buff.ly/6LKIB1y
💷 £37,500 to £40,240
🗓️ Apply by 30 November 2025
➡️ buff.ly/6LKIB1y
November 7, 2025 at 3:00 PM
🆕 Vacancy! We're looking for a Research Scientist to work on novel platforms for sustainable myco-food production and precision fermentation.
💷 £37,500 to £40,240
🗓️ Apply by 30 November 2025
➡️ buff.ly/6LKIB1y
💷 £37,500 to £40,240
🗓️ Apply by 30 November 2025
➡️ buff.ly/6LKIB1y
Reposted by Melania D'Angiolo
Applications are open for our 2026 #PhD programme at the Earlham Institute.
Discover the projects available across crop and fungi #genomics, cell biology, human health, and #engineeringbiology.
👉 buff.ly/YdDXoSd
Discover the projects available across crop and fungi #genomics, cell biology, human health, and #engineeringbiology.
👉 buff.ly/YdDXoSd
November 7, 2025 at 12:01 PM
Applications are open for our 2026 #PhD programme at the Earlham Institute.
Discover the projects available across crop and fungi #genomics, cell biology, human health, and #engineeringbiology.
👉 buff.ly/YdDXoSd
Discover the projects available across crop and fungi #genomics, cell biology, human health, and #engineeringbiology.
👉 buff.ly/YdDXoSd
Reposted by Melania D'Angiolo
The new issue of #Yeast of 2025 (Volume 42, Issue 11, November 2025) is out! It includes papers about new yeast genomes, the biodiversity of yeasts in dough, polyphosphate accumulation and even a new #FantasticYeasts species 😃
You can browse it at this link:
onlinelibrary.wiley.com/toc/10970061...
You can browse it at this link:
onlinelibrary.wiley.com/toc/10970061...
Happy 40th birthday Yeast: Yeast: Vol 42, No 11
Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.
onlinelibrary.wiley.com
November 5, 2025 at 3:59 PM
The new issue of #Yeast of 2025 (Volume 42, Issue 11, November 2025) is out! It includes papers about new yeast genomes, the biodiversity of yeasts in dough, polyphosphate accumulation and even a new #FantasticYeasts species 😃
You can browse it at this link:
onlinelibrary.wiley.com/toc/10970061...
You can browse it at this link:
onlinelibrary.wiley.com/toc/10970061...
Reposted by Melania D'Angiolo
In the latest #Yeast research article, Alexander Deitert, Lars M. Blank and team investigated the effect of zinc and inositol in polyphosphate accumulation in Saccharomyces cerevisiae, revealing their role in energy metabolism and phosphate signalling.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Polyphosphate Accumulation Is Determined by Zinc and Inositol in Saccharomyces cerevisiae
Zinc and inositol supplementation during phosphate starvation significantly enhances final polyphosphate levels in S. cerevisiae.
onlinelibrary.wiley.com
October 29, 2025 at 11:19 AM
In the latest #Yeast research article, Alexander Deitert, Lars M. Blank and team investigated the effect of zinc and inositol in polyphosphate accumulation in Saccharomyces cerevisiae, revealing their role in energy metabolism and phosphate signalling.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Melania D'Angiolo
In this new #Yeast research article Yueting Zheng, Wei Yang, Wei Zhang & teams developed a new expression vector system to produce exogenous proteins in Kluyveromyces marxianus, and they successfully expressed the cap gene of porcine circovirus type 3 (PCV3).
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Characterization of Vector Elements and Soluble Expression of Pcv3 Cap Protein in Kluyveromyces Marxianus
We engineered a vector system that was suitable for Kluyveromyces marxianus-based recombinant protein expression. Endogenous promoter PDC1 with high expression strength was used in this vector system...
onlinelibrary.wiley.com
October 27, 2025 at 12:40 PM
In this new #Yeast research article Yueting Zheng, Wei Yang, Wei Zhang & teams developed a new expression vector system to produce exogenous proteins in Kluyveromyces marxianus, and they successfully expressed the cap gene of porcine circovirus type 3 (PCV3).
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Melania D'Angiolo
Nature research paper: From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes
go.nature.com/4nVsl9z
go.nature.com/4nVsl9z
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes - Nature
A newly compiled atlas of species-wide structural variants and gene-based and graph pangenomes derived from highly complete assemblies of genomes from 1,086 natural isolates enable integrative genome-scale studies of Saccharomyces cerevisiae.
go.nature.com
October 20, 2025 at 6:19 PM
Nature research paper: From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes
go.nature.com/4nVsl9z
go.nature.com/4nVsl9z
Reposted by Melania D'Angiolo
Pleased to share our latest #AEM publication showing that #yeast Rhodotorula toruloides’ sense and response mechanism for nitrogen can be deployed for exopolysaccharide #biopolymer production (h/t @asm.org). A brief thread 🧵
Illustration credit: Dr. Stefania Vaga (h/t @cofactor.bsky.social)
Illustration credit: Dr. Stefania Vaga (h/t @cofactor.bsky.social)
October 24, 2025 at 2:08 PM
Pleased to share our latest #AEM publication showing that #yeast Rhodotorula toruloides’ sense and response mechanism for nitrogen can be deployed for exopolysaccharide #biopolymer production (h/t @asm.org). A brief thread 🧵
Illustration credit: Dr. Stefania Vaga (h/t @cofactor.bsky.social)
Illustration credit: Dr. Stefania Vaga (h/t @cofactor.bsky.social)
Reposted by Melania D'Angiolo
www.embopress.org/doi/full/10....
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
For the love of frontier research, or why Elon’s rockets keep blowing up | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
October 25, 2025 at 4:48 PM
www.embopress.org/doi/full/10....
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
Here's an important and topical perspective from Nektarios Tavernarakis. Wise words!
Reposted by Melania D'Angiolo
NEW GENOME ALERT 👇: in this new #Yeast research article
@dmattanovich.bsky.social , Brigitte Gasser, Alexandra B. Graf and team published the complete and annotated genome sequence of the Komagataella phaffii type strain, revealing new genes and SNPs.
onlinelibrary.wiley.com/doi/10.1002/...
@dmattanovich.bsky.social , Brigitte Gasser, Alexandra B. Graf and team published the complete and annotated genome sequence of the Komagataella phaffii type strain, revealing new genes and SNPs.
onlinelibrary.wiley.com/doi/10.1002/...
October 22, 2025 at 2:53 PM
NEW GENOME ALERT 👇: in this new #Yeast research article
@dmattanovich.bsky.social , Brigitte Gasser, Alexandra B. Graf and team published the complete and annotated genome sequence of the Komagataella phaffii type strain, revealing new genes and SNPs.
onlinelibrary.wiley.com/doi/10.1002/...
@dmattanovich.bsky.social , Brigitte Gasser, Alexandra B. Graf and team published the complete and annotated genome sequence of the Komagataella phaffii type strain, revealing new genes and SNPs.
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Melania D'Angiolo
Ever wondered what is in your Tarhana dough? In the latest #Yeast research article, Burcu Ozel, Bilal Agirman, Omer Simsek and Huseyin Erten investigated the effects of backslopping on the yeast and volatile aroma compound diversity of tarhana.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
October 20, 2025 at 3:15 PM
Ever wondered what is in your Tarhana dough? In the latest #Yeast research article, Burcu Ozel, Bilal Agirman, Omer Simsek and Huseyin Erten investigated the effects of backslopping on the yeast and volatile aroma compound diversity of tarhana.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Melania D'Angiolo
In this issue (Volume 42, Issue 8-10, September 2025) you will find papers about the genetic modification and characterization of multiple yeast species (S. cerevisiae, O. polymorpha and K. phaffii) to produce useful compounds, as well as new insights into the TORC1 signalling pathway.
October 15, 2025 at 8:15 AM
In this issue (Volume 42, Issue 8-10, September 2025) you will find papers about the genetic modification and characterization of multiple yeast species (S. cerevisiae, O. polymorpha and K. phaffii) to produce useful compounds, as well as new insights into the TORC1 signalling pathway.
Reposted by Melania D'Angiolo
The new issue of #Yeast is out ... with a surprise 😄! This issue marks the 40th anniversary of the creation of our journal, in 1985. To celebrate this achievement, we made a brand new cover with the most beautiful #Yeast front pages 😍
Happy birthday Yeast!!!
onlinelibrary.wiley.com/toc/10970061...
Happy birthday Yeast!!!
onlinelibrary.wiley.com/toc/10970061...
Happy 40th birthday Yeast: Yeast: Vol 42, No 8-10
Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.
onlinelibrary.wiley.com
October 15, 2025 at 8:03 AM
The new issue of #Yeast is out ... with a surprise 😄! This issue marks the 40th anniversary of the creation of our journal, in 1985. To celebrate this achievement, we made a brand new cover with the most beautiful #Yeast front pages 😍
Happy birthday Yeast!!!
onlinelibrary.wiley.com/toc/10970061...
Happy birthday Yeast!!!
onlinelibrary.wiley.com/toc/10970061...
Reposted by Melania D'Angiolo
Big congratulations to Dilanaz Arisan (@rquatrini.bsky.social 's lab) and Pablo Quintrel (@fcocubillosr.bsky.social 's lab) for winning the best posters awards sponsored by the #Yeast journal at the @smbe-chile2025.bsky.social conference in Puerto Varas 🎉🎉🎉
October 13, 2025 at 9:06 AM
Big congratulations to Dilanaz Arisan (@rquatrini.bsky.social 's lab) and Pablo Quintrel (@fcocubillosr.bsky.social 's lab) for winning the best posters awards sponsored by the #Yeast journal at the @smbe-chile2025.bsky.social conference in Puerto Varas 🎉🎉🎉
Reposted by Melania D'Angiolo
REMINDER: only two weeks left to submit papers to the special issue of "Yeast in microbiomes". There will be no further extensions.
The deadline for submissions to the special issue "Yeast in Microbiomes" has been extended to 15 October. We accept manuscripts exploring yeast diversity, interactions, and adaptations in diverse host environments. Hurry up and don't miss this opportunity!!!
onlinelibrary.wiley.com/page/journal...
onlinelibrary.wiley.com/page/journal...
Yeast Call for Papers: Yeast in Microbiomes
Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.
onlinelibrary.wiley.com
October 3, 2025 at 7:38 AM
REMINDER: only two weeks left to submit papers to the special issue of "Yeast in microbiomes". There will be no further extensions.
Reposted by Melania D'Angiolo
In the latest #Yeast research article, Somsak Likhitrattanapisal, Niran Roongsawang and team investigated the genome of Ogataea polymorpha and its transcriptomic response during growth in sucrose-supplemented medium.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Sucrose‐Induced Transcriptomic Response in Ogataea polymorpha TBRC 4839 Reveals its Potential for Recombinant Protein Production
Sucrose induction in Ogataea polymorpha triggers a metabolic shift, enhancing carbohydrate metabolism while suppressing amino acid biosynthesis, stress signaling, and cell division. This adaptation o....
onlinelibrary.wiley.com
October 1, 2025 at 11:20 AM
In the latest #Yeast research article, Somsak Likhitrattanapisal, Niran Roongsawang and team investigated the genome of Ogataea polymorpha and its transcriptomic response during growth in sucrose-supplemented medium.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...