Our paper on ovarian cancer #LGSC is out in @Cancer_Cell. Using deep visual proteomics #DVP and spatial transcriptomics, we mapped how non-invasive tumors become deadly ovarian disease, and found a promising new treatment combination.
www.cell.com/cancer-cell/...

Thrilled to share that our manuscript mapping proteomic & phosphoproteomic signatures of NGT, T2D, males & females — before and after hyperinsulinemic-euglycemic clamp — is now accepted in Cell.

@annakrook.bsky.social @juleenrzierath.bsky.social
@cbmr.science

doi.org/10.1016/j.ce...

There a lot of use of NAD+ supplements out there, without evidence of anti-aging effects in people. Here's some new data that detracts from NAD's role in modulating the aging process
www.cell.com/cell-metabol...

On becoming an autocracy @newyorker.com
www.newyorker.com/magazine/202...

My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...

After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.

Our paper is out in Nature today! We use Deep Visual Proteomics (DVP) to dissect α1-antitrypsin deficiency (AATD) in human liver at single-cell resolution.
Let us take a tour through proteotoxic stress in intact human tissue — one hepatocyte at a time.
www.nature.com/articles/s41...

I am a professor at Columbia University. All of the student NIH training grants have been canceled and now there are reports that ALL funding will be frozen. Why are Universities not banding together and speaking out publicly and forcibly about governmental attacks on biomedical research?

😢 this is not normal. And we should not turn away from this illegal BS!

“It is up to all of us to fix this. It’s not going to be because somebody comes and saves you.” - President Obama yesterday

We must organize the pro-democracy majority to reclaim its power. Join an event near you for tomorrow’s nationwide day of action: handsoff2025.com?SQF_SOURCE=i...

Eine freie Wissenschaft gehört zum Kern liberaler, demokratischer Gesellschaften.

Es ist in höchstem Maße besorgniserregend, dass die Freiheit der Wissenschaft in verschiedenen Regionen der Welt zunehmend unter Druck gerät.

With everything happening in the US right now, how safe are scientific conferences for foreign participants in the US? I think this is something we have to discuss as a scientific community. I am hesitating to register for US meetings due to the unpredictable situation. Others who feel the same?

Beautiful, powerful letter

I have been asked by Harvard colleagues if they should keep quiet so as not put the larger Harvard community at risk with their words

Took me a while to ruminate

My response:

Harvard is its people and their voices

If we are silent then there is no Harvard to save

While, in a nice collaboration with the Carvalho lab and @joanavferreira.bsky.social, PhD student Yara Ahmed used MD simulations to characterize the binding mechanism of the Dysferlin domain of Pex30 to phosphatidic acid. Anyone interested in a novel PA-sensor? (2/2)
www.biorxiv.org/content/10.1...

It is important at this pivotal moment to @standupforscience.bsky.social. Looking forward to sharing my thoughts on why this should be a national priority at tomorrow’s rally in SF:

Time to fight !

@moiradonegan.bsky.social: „Now, the Democrats seem less like a resistance than an acquiescence. They are not mounting any meaningful opposition to Trump’s aggressive, sadistic mission. Instead they’re rolling over, like a submissive dog showing its belly, …“ www.theguardian.com/commentisfre...

Congratulations!

Seeing in real time the same event unfolding as 1933 in Germany and most institutions are compliant....where are democrats, church, science organizations like HHMI or NAS, economy? Pubmed might not be the biggest problem right now

One week left to register! Registration possible until the 28th of February. Do not miss this chance! 🔥

The self censorship and appeasement by *National Academies of science* is really disturbing.
How do you stand for science and freedom of academic research when you self censor terms such as “health equity”?
It really takes you back to dark, dark days…

Our new fashion collection for future mass spectrometrists 🤩 designed by Eva Trautmann

A great resource for the field of adipose tissue biology! Check it out

#Adiposetissue.org: New Knowledge Portal Enhances Obesity and Metabolism Research

👉 Discover more about the platform in our news: t1p.de/cogg2

@ki.se #HelmholtzMunich

#ObesityResearch #Metabolism #Bioinformatics #AdiposeTissue #Obesity #Diabetes #HI_MAGLeipzig #metabolism