Lorena Oli
@olifiersl.bsky.social
PhD student at the Max Planck for Biological Intelligence & GSN-LMU | prev. at University of Manchester | looking closely at neuronal mitochondria 🔬
#nerdfighter
#nerdfighter
Check out my first @prelights.bsky.social article, based on some great work done by Dr. Tejashree Waingankar & @samlewis.bsky.social at UC Berkeley 🔬🧬🧠
prelights.biologists.com/highlights/s...
prelights.biologists.com/highlights/s...
Self-renewal of neuronal mitochondria through asymmetric division - preLights
Neurons contain “hotspots” for mitochondrial biogenesis at distal branch points
prelights.biologists.com
February 6, 2026 at 6:23 PM
Check out my first @prelights.bsky.social article, based on some great work done by Dr. Tejashree Waingankar & @samlewis.bsky.social at UC Berkeley 🔬🧬🧠
prelights.biologists.com/highlights/s...
prelights.biologists.com/highlights/s...
Reposted by Lorena Oli
The moment to celebrate a paper is when it’s shared with the world, not when it passes the arbitrary hurdle of “acceptance”
February 6, 2026 at 7:41 AM
The moment to celebrate a paper is when it’s shared with the world, not when it passes the arbitrary hurdle of “acceptance”
Reposted by Lorena Oli
Schwarz lab @bostonchildrens.bsky.social identify a mechanism coupling mitochondrial movement to energy demand. When energy levels are low, the energy-sensing kinase AMPK phosphorylates the motor/adaptor protein TRAK1, arresting #mitochondria via the #actin #cytoskeleton. rupress.org/jcb/article/...
January 30, 2026 at 5:00 PM
Schwarz lab @bostonchildrens.bsky.social identify a mechanism coupling mitochondrial movement to energy demand. When energy levels are low, the energy-sensing kinase AMPK phosphorylates the motor/adaptor protein TRAK1, arresting #mitochondria via the #actin #cytoskeleton. rupress.org/jcb/article/...
Reposted by Lorena Oli
It’s not so much that Trump & co don’t think slavery was important, they want to remove this history precisely *because* of how important it was. They don’t want people to learn about slavery because then people would understand how it continues to shape the landscape of inequality in America today.
Signs about the history of slavery in the U.S. and the 9 people George Washington enslaved are being removed right now at the President’s House Site in Philadelphia, across from Independence Hall, months after the Trump administration threatend to do so.
How far we have not come in 250 years.
How far we have not come in 250 years.
January 22, 2026 at 10:19 PM
It’s not so much that Trump & co don’t think slavery was important, they want to remove this history precisely *because* of how important it was. They don’t want people to learn about slavery because then people would understand how it continues to shape the landscape of inequality in America today.
Reposted by Lorena Oli
Research with fruit flies could unlock riddle of neurodegenerative disorders www.manchester.ac.uk/about/news/r... by @manchester.ac.uk
#Alzheimers #dementia #Parkinsons #MND #neuroscience #NeuroSkyence
#Alzheimers #dementia #Parkinsons #MND #neuroscience #NeuroSkyence
Research with fruit flies could unlock riddle of neurodegenerative disorders
A study by University of Manchester scientists using fruit flies as model has identified a mechanism which can explain aspects of neurodegeneration which have baffled scientists for decades.Scientists...
www.manchester.ac.uk
January 21, 2026 at 2:04 AM
Research with fruit flies could unlock riddle of neurodegenerative disorders www.manchester.ac.uk/about/news/r... by @manchester.ac.uk
#Alzheimers #dementia #Parkinsons #MND #neuroscience #NeuroSkyence
#Alzheimers #dementia #Parkinsons #MND #neuroscience #NeuroSkyence
Reposted by Lorena Oli
Davos, Switzerland, the World Economic Forum.
January 20, 2026 at 10:16 PM
Davos, Switzerland, the World Economic Forum.
Reposted by Lorena Oli
Loss & gain of motor protein function cause microtubule bundle damage in 🪰 axons: @currentbiology.bsky.social Biology www.cell.com/current-biol... @poppi62.bsky.social
Loss and gain of motor protein function cause microtubule bundle damage in Drosophila axons
Liew et al. show that neurodegeneration-linked mutations of different transport motor
classes cause damage to axonal microtubule bundles in the form of microtubule-curling.
Transport loss of mitochond...
www.cell.com
January 19, 2026 at 3:48 PM
Loss & gain of motor protein function cause microtubule bundle damage in 🪰 axons: @currentbiology.bsky.social Biology www.cell.com/current-biol... @poppi62.bsky.social
Reposted by Lorena Oli
My quote of the day
I must uphold my ideals, for perhaps the time will come when I shall be able to carry them out.
Anne Frank
I must uphold my ideals, for perhaps the time will come when I shall be able to carry them out.
Anne Frank
January 20, 2026 at 10:57 AM
My quote of the day
I must uphold my ideals, for perhaps the time will come when I shall be able to carry them out.
Anne Frank
I must uphold my ideals, for perhaps the time will come when I shall be able to carry them out.
Anne Frank
Reposted by Lorena Oli
New preprint from my lab!!!
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
Mitochondrial hitch-hiking of Mapt mRNA maintains Tau levels in axons
Hitch-hiking of transcripts on organelles, including mitochondria, has emerged as a common pathway to transport mRNAs into the axon to enable their local translation. However, the extent of mitochondr...
shorturl.at
January 15, 2026 at 10:17 AM
New preprint from my lab!!!
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
Reposted by Lorena Oli
🚨 REGISTRATION NOW OPEN – CAJAL CONFERENCE 2026
“Novel Insights Into Brain Energy Metabolism in Health and Disease”
📍 April 15–17, 2026 | Cádiz, Spain
🔔 SENC Fellowships available 🔔 20 slots for Oral Communications
👉🏻 Register here:
amconferences.eventsair.com/senc-cajal-c...
👇🏻 SPEAKERS
“Novel Insights Into Brain Energy Metabolism in Health and Disease”
📍 April 15–17, 2026 | Cádiz, Spain
🔔 SENC Fellowships available 🔔 20 slots for Oral Communications
👉🏻 Register here:
amconferences.eventsair.com/senc-cajal-c...
👇🏻 SPEAKERS
January 12, 2026 at 5:06 PM
🚨 REGISTRATION NOW OPEN – CAJAL CONFERENCE 2026
“Novel Insights Into Brain Energy Metabolism in Health and Disease”
📍 April 15–17, 2026 | Cádiz, Spain
🔔 SENC Fellowships available 🔔 20 slots for Oral Communications
👉🏻 Register here:
amconferences.eventsair.com/senc-cajal-c...
👇🏻 SPEAKERS
“Novel Insights Into Brain Energy Metabolism in Health and Disease”
📍 April 15–17, 2026 | Cádiz, Spain
🔔 SENC Fellowships available 🔔 20 slots for Oral Communications
👉🏻 Register here:
amconferences.eventsair.com/senc-cajal-c...
👇🏻 SPEAKERS
Reposted by Lorena Oli
How do cells assess mtDNA quality?
Local ATP and membrane-potential gradients reflect mtDNA integrity and drive intracellular purifying selection.
We introduce FAST, a scalable mtDNA QC assay in S. cerevisiae.
Great collaboration with the Schmoller Lab.
journals.plos.org/plosgenetics...
🧬⚡
Local ATP and membrane-potential gradients reflect mtDNA integrity and drive intracellular purifying selection.
We introduce FAST, a scalable mtDNA QC assay in S. cerevisiae.
Great collaboration with the Schmoller Lab.
journals.plos.org/plosgenetics...
🧬⚡
Local mitochondrial physiology defined by mtDNA quality guides purifying selection
Author summary Mitochondria are essential organelles in our cells that convert nutrients into usable cellular energy. They contain their own DNA, and mutations in this DNA can compromise mitochondrial...
journals.plos.org
January 10, 2026 at 4:00 PM
How do cells assess mtDNA quality?
Local ATP and membrane-potential gradients reflect mtDNA integrity and drive intracellular purifying selection.
We introduce FAST, a scalable mtDNA QC assay in S. cerevisiae.
Great collaboration with the Schmoller Lab.
journals.plos.org/plosgenetics...
🧬⚡
Local ATP and membrane-potential gradients reflect mtDNA integrity and drive intracellular purifying selection.
We introduce FAST, a scalable mtDNA QC assay in S. cerevisiae.
Great collaboration with the Schmoller Lab.
journals.plos.org/plosgenetics...
🧬⚡
Reposted by Lorena Oli
US-Vizepräsident JD Vance sieht vor, dass die ICE-Mitarbeiter von "Tür zu Tür" gehen sollen, um die Dokumente der Menschen zu prüfen.
Gleichzeitig genießen sie laut ihm "voll Immunität".
An was erinnert euch das?
Gleichzeitig genießen sie laut ihm "voll Immunität".
An was erinnert euch das?
January 11, 2026 at 8:28 AM
US-Vizepräsident JD Vance sieht vor, dass die ICE-Mitarbeiter von "Tür zu Tür" gehen sollen, um die Dokumente der Menschen zu prüfen.
Gleichzeitig genießen sie laut ihm "voll Immunität".
An was erinnert euch das?
Gleichzeitig genießen sie laut ihm "voll Immunität".
An was erinnert euch das?
Reposted by Lorena Oli
Reposted by Lorena Oli
🔬 🖥️ Applications are open for the CSHL course Quantitative Imaging: From Acquisition to Analysis (April 6–21, 2026)!
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
Quantitative Imaging: From Acquisition to Analysis
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
meetings.cshl.edu
January 6, 2026 at 7:18 PM
🔬 🖥️ Applications are open for the CSHL course Quantitative Imaging: From Acquisition to Analysis (April 6–21, 2026)!
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
Reposted by Lorena Oli
Medina, Chang et al. of the @nanigrotjahn.bsky.social lab introduce a new method based on the Surface Morphometrics pipeline to measure global and local thicknesses of organellar #membranes from cellular cryo-electron tomography data. rupress.org/jcb/article/...
#CryoET
#CryoET
January 5, 2026 at 8:15 PM
Medina, Chang et al. of the @nanigrotjahn.bsky.social lab introduce a new method based on the Surface Morphometrics pipeline to measure global and local thicknesses of organellar #membranes from cellular cryo-electron tomography data. rupress.org/jcb/article/...
#CryoET
#CryoET
Reposted by Lorena Oli
Hey, science community (whoever is here). Can you please help me amplify this message? Postdoc position available in Düsseldorf!
January 5, 2026 at 1:33 PM
Hey, science community (whoever is here). Can you please help me amplify this message? Postdoc position available in Düsseldorf!
who needs a CV when you have this lovely statement from when you were in 3rd grade 🥹🥹
thanks Cyrus
thanks Cyrus
January 4, 2026 at 10:55 PM
who needs a CV when you have this lovely statement from when you were in 3rd grade 🥹🥹
thanks Cyrus
thanks Cyrus
Reposted by Lorena Oli
Excited to share our new paper! 🎉
we explored foraging behavior, contaminant exposure ( #Hg & #PFAS), and mitochondrial bioenergetics, revealing how #pollution can affect cellular energy in an apex marine predator @stefi-casagrande.bsky.social
#mitochondria
pubs.acs.org/doi/full/10....
we explored foraging behavior, contaminant exposure ( #Hg & #PFAS), and mitochondrial bioenergetics, revealing how #pollution can affect cellular energy in an apex marine predator @stefi-casagrande.bsky.social
#mitochondria
pubs.acs.org/doi/full/10....
Pollutant Exposure Shapes Mitochondrial Bioenergetics in a Wild Seabird
Laboratory studies show that mercury (Hg) and per- and polyfluoroalkyl substances (PFAS) can impair mitochondrial bioenergetics, which is a vital process for cellular energy production. However, their...
pubs.acs.org
December 28, 2025 at 6:43 PM
Excited to share our new paper! 🎉
we explored foraging behavior, contaminant exposure ( #Hg & #PFAS), and mitochondrial bioenergetics, revealing how #pollution can affect cellular energy in an apex marine predator @stefi-casagrande.bsky.social
#mitochondria
pubs.acs.org/doi/full/10....
we explored foraging behavior, contaminant exposure ( #Hg & #PFAS), and mitochondrial bioenergetics, revealing how #pollution can affect cellular energy in an apex marine predator @stefi-casagrande.bsky.social
#mitochondria
pubs.acs.org/doi/full/10....
Reposted by Lorena Oli
All research is exploratory if you’re confused enough
December 19, 2025 at 8:01 AM
All research is exploratory if you’re confused enough
Reposted by Lorena Oli
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Self-renewal of neuronal mitochondria through asymmetric division
Mitochondrial ATP production is essential for life. Mitochondrial function depends on the spatio-temporal coordination of nuclear and mitochondrial genome expression, yet how this coordination occurs ...
www.biorxiv.org
December 18, 2025 at 8:36 PM
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
spotted in Munich @matthewcobb.bsky.social
December 18, 2025 at 8:09 PM
spotted in Munich @matthewcobb.bsky.social
Life is what happens in between your image acquisition sessions
Life is what happens when you’re busy trying to get your paper published
December 17, 2025 at 5:50 PM
Life is what happens in between your image acquisition sessions
Reposted by Lorena Oli
Spatial and morphological organization of mitochondria in neurons across a connectome | Science www.science.org/doi/10.1126/...
Spatial and morphological organization of mitochondria in neurons across a connectome
Neuronal function depends on mitochondria, but little is known about their organization across neurons. Using an electron microscopy Drosophila connectome, we uncovered quantitative rules governing th...
www.science.org
December 11, 2025 at 7:26 PM
Spatial and morphological organization of mitochondria in neurons across a connectome | Science www.science.org/doi/10.1126/...
Reposted by Lorena Oli
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
Visual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus - Nature Communications
How are various visual signals integrated in the vertebrate brain for navigation? Here authors show that different spatial signals are topographically organized and align to one another in the zebrafi...
www.nature.com
November 24, 2025 at 4:17 PM
(1/n) We are excited to share our new paper in Nature Communications, by Hagar Lavian (@hlavian.bsky.social) and team, revealing how the zebrafish brain integrates visual navigation signals! www.nature.com/articles/s41...
highlight of the pub quiz in a room full of neuroscientists
December 2, 2025 at 3:22 PM
highlight of the pub quiz in a room full of neuroscientists